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Items: 1 to 50 of 106

1.

Evaluation of Abicipar Pegol (an Anti-VEGF DARPin Therapeutic) in Patients With Neovascular Age-Related Macular Degeneration: Studies in Japan and the United States.

Kunimoto D, Ohji M, Maturi RK, Sekiryu T, Wang Y, Pan G, Li XY, Schneider S; BAMBOO and CYPRESS Study Groups.

Ophthalmic Surg Lasers Imaging Retina. 2019 Feb 1;50(2):e10-e22. doi: 10.3928/23258160-20190129-13.

PMID:
30768224
3.

Double-Masked, Randomized, Phase 2 Evaluation of Abicipar Pegol (an Anti-VEGF DARPin Therapeutic) in Neovascular Age-Related Macular Degeneration.

Callanan D, Kunimoto D, Maturi RK, Patel SS, Staurenghi G, Wolf S, Cheetham JK, Hohman TC, Kim K, López FJ, Schneider S.

J Ocul Pharmacol Ther. 2018 Nov 9. doi: 10.1089/jop.2018.0062. [Epub ahead of print]

4.

Future Path Toward TB Vaccine Development: Boosting BCG or Re-educating by a New Subunit Vaccine.

Gupta N, Garg S, Vedi S, Kunimoto DY, Kumar R, Agrawal B.

Front Immunol. 2018 Oct 16;9:2371. doi: 10.3389/fimmu.2018.02371. eCollection 2018.

5.

Characterization of immune responses of human PBMCs infected with Mycobacterium tuberculosis H37Ra: Impact of donor declared BCG vaccination history on immune responses and M. tuberculosis growth.

Bhavanam S, Rayat GR, Keelan M, Kunimoto D, Drews SJ.

PLoS One. 2018 Sep 11;13(9):e0203822. doi: 10.1371/journal.pone.0203822. eCollection 2018.

6.

Towards the elimination of paediatric tuberculosis in high-income, immigrant-receiving countries: a 25-year conventional and molecular epidemiological case study.

Dhawan V, Bown J, Lau A, Langlois-Klassen D, Kunimoto D, Bhargava R, Chui L, Collin SM, Long R.

ERJ Open Res. 2018 May 8;4(2). pii: 00131-2017. doi: 10.1183/23120541.00131-2017. eCollection 2018 Apr.

7.

Mycobacterium chimaera Infection After Aortic Valve Replacement Presenting With Aortic Dissection and Pseudoaneurysm.

O'Neil CR, Taylor G, Smith S, Joffe AM, Antonation K, Shafran S, Kunimoto D.

Open Forum Infect Dis. 2018 Jan 24;5(2):ofy018. doi: 10.1093/ofid/ofy018. eCollection 2018 Feb.

8.

Tuberculosis transmission in the Indigenous peoples of the Canadian prairies.

Patel S, Paulsen C, Heffernan C, Saunders D, Sharma M, King M, Hoeppner V, Orr P, Kunimoto D, Menzies D, Christianson S, Wolfe J, Boffa J, McMullin K, Lopez-Hille C, Senthilselvan A, Long R.

PLoS One. 2017 Nov 14;12(11):e0188189. doi: 10.1371/journal.pone.0188189. eCollection 2017.

9.

Effect of Bevacizumab vs Aflibercept on Visual Acuity Among Patients With Macular Edema Due to Central Retinal Vein Occlusion: The SCORE2 Randomized Clinical Trial.

Scott IU, VanVeldhuisen PC, Ip MS, Blodi BA, Oden NL, Awh CC, Kunimoto DY, Marcus DM, Wroblewski JJ, King J; SCORE2 Investigator Group.

JAMA. 2017 May 23;317(20):2072-2087. doi: 10.1001/jama.2017.4568.

10.

Novel lipopeptides of ESAT-6 induce strong protective immunity against Mycobacterium tuberculosis: Routes of immunization and TLR agonists critically impact vaccine's efficacy.

Gupta N, Vedi S, Kunimoto DY, Agrawal B, Kumar R.

Vaccine. 2016 Nov 4;34(46):5677-5688. doi: 10.1016/j.vaccine.2016.08.075. Epub 2016 Sep 29.

PMID:
27693020
11.

Investigation of C-5 alkynyl (alkynyloxy or hydroxymethyl) and/or N-3 propynyl substituted pyrimidine nucleoside analogs as a new class of antimicrobial agents.

Garg S, Shakya N, Srivastav NC, Agrawal B, Kunimoto DY, Kumar R.

Bioorg Med Chem. 2016 Nov 1;24(21):5521-5533. doi: 10.1016/j.bmc.2016.09.008. Epub 2016 Sep 12.

PMID:
27665179
12.

Understanding the pathophysiology of the human TB lung granuloma using in vitro granuloma models.

Bhavanam S, Rayat GR, Keelan M, Kunimoto D, Drews SJ.

Future Microbiol. 2016 Aug;11:1073-89. doi: 10.2217/fmb-2016-0005. Epub 2016 Aug 9. Review.

PMID:
27501829
13.

Serum drug concentrations of INH and RMP predict 2-month sputum culture results in tuberculosis patients.

Mah A, Kharrat H, Ahmed R, Gao Z, Der E, Hansen E, Long R, Kunimoto D, Cooper R.

Int J Tuberc Lung Dis. 2015 Feb;19(2):210-5. doi: 10.5588/ijtld.14.0405.

PMID:
25574921
14.

Factors associated with noncompletion of latent tuberculosis infection treatment in an inner-city population in Edmonton, Alberta.

Malejczyk K, Gratrix J, Beckon A, Moreau D, Williams G, Kunimoto D, Ahmed R.

Can J Infect Dis Med Microbiol. 2014 Sep;25(5):281-4.

15.

Changing epidemiology of tuberculosis detected by an 8-year retrospective laboratory study in a tertiary teaching hospital in central Saudi Arabia.

Somily AM, Naeem T, Habib HA, Sarwar MS, Kunimoto DY, Kambal AM.

Saudi Med J. 2014 Jul;35(7):691-8.

PMID:
25028225
16.

Assessment of linezolid efficacy, safety and tolerability in the treatment of tuberculosis: A retrospective case review.

Tse-Chang A, Kunimoto D, Der E, Ahmed R.

Can J Infect Dis Med Microbiol. 2013 Fall;24(3):e50-2.

17.

Marked disparity in the epidemiology of tuberculosis among Aboriginal peoples on the Canadian prairies: the challenges and opportunities.

Long R, Hoeppner V, Orr P, Ainslie M, King M, Abonyi S, Mayan M, Kunimoto D, Langlois-Klassen D, Heffernan C, Lau A, Menzies D.

Can Respir J. 2013 Jul-Aug;20(4):223-30. Epub 2013 May 28.

18.

Transmission of Mycobacterium tuberculosis Beijing Strains, Alberta, Canada, 1991-2007.

Langlois-Klassen D, Senthilselvan A, Chui L, Kunimoto D, Saunders LD, Menzies D, Long R.

Emerg Infect Dis. 2013 May;19(5):701-11. doi: 10.3201/eid1905.121578.

19.

A shelter-associated tuberculosis outbreak: a novel strain introduced through foreign-born populations.

Moreau D, Gratrix J, Kunimoto D, Beckon A, Der E, Hansen E, Chui L, Ahmed R.

Can J Public Health. 2012 Nov 6;103(6):e408-12.

PMID:
23618017
20.

Factors associated with reduced antituberculous serum drug concentrations in patients with HIV-TB coinfection.

Ahmed R, Cooper R, Foisy M, Der E, Kunimoto D.

J Int Assoc Physicians AIDS Care (Chic). 2012 Sep-Oct;11(5):273-6. Epub 2012 Aug 8.

PMID:
22875581
21.

A population-based cohort study of Mycobacterium tuberculosis Beijing strains: an emerging public health threat in an immigrant-receiving country?

Langlois-Klassen D, Kunimoto D, Saunders LD, Chui L, Boffa J, Menzies D, Long R.

PLoS One. 2012;7(6):e38431. doi: 10.1371/journal.pone.0038431. Epub 2012 Jun 5.

22.

Discovery of novel 5-(ethyl or hydroxymethyl) analogs of 2'-'up' fluoro (or hydroxyl) pyrimidine nucleosides as a new class of Mycobacterium tuberculosis, Mycobacterium bovis and Mycobacterium avium inhibitors.

Shakya N, Srivastav NC, Bhavanam S, Tse C, Desroches N, Agrawal B, Kunimoto DY, Kumar R.

Bioorg Med Chem. 2012 Jul 1;20(13):4088-97. doi: 10.1016/j.bmc.2012.05.004. Epub 2012 May 15.

PMID:
22664188
23.

Antimycobacterial activities of 5-alkyl (or halo)-3'-substituted pyrimidine nucleoside analogs.

Srivastav NC, Shakya N, Bhavanam S, Agrawal A, Tse C, Desroches N, Kunimoto DY, Kumar R.

Bioorg Med Chem Lett. 2012 Jan 15;22(2):1091-4. doi: 10.1016/j.bmcl.2011.11.114. Epub 2011 Dec 4.

PMID:
22178557
24.

The tuberculin skin test is unreliable in school children BCG-vaccinated in infancy and at low risk of tuberculosis infection.

Jacobs S, Warman A, Richardson R, Yacoub W, Lau A, Whittaker D, Cockburn S, Verma G, Boffa J, Tyrrell G, Kunimoto D, Manfreda J, Langlois-Klassen D, Long R.

Pediatr Infect Dis J. 2011 Sep;30(9):754-8. doi: 10.1097/INF.0b013e31821b8f54.

PMID:
21487326
25.

Induced sputum for the diagnosis of pulmonary tuberculosis: Is it useful in clinical practice?

Olsen SR, Long R, Tyrrell G, Kunimoto D.

Can Respir J. 2010 Jul-Aug;17(4):e81-4.

26.

Sustained intra- and inter-jurisdictional transmission of tuberculosis within a mobile, multi-ethnic social network: lessons for tuberculosis elimination.

Aspler A, Chong H, Kunimoto D, Chui L, Der E, Boffa J, Long R.

Can J Public Health. 2010 May-Jun;101(3):205-9.

PMID:
20737810
27.

Inhibition of mycobacterial replication by pyrimidines possessing various C-5 functionalities and related 2'-deoxynucleoside analogues using in vitro and in vivo models.

Srivastav NC, Rai D, Tse C, Agrawal B, Kunimoto DY, Kumar R.

J Med Chem. 2010 Aug 26;53(16):6180-7. doi: 10.1021/jm100568q.

PMID:
20718497
28.

Antimycobacterial screening of traditional medicinal plants using the microplate resazurin assay.

Webster D, Lee TD, Moore J, Manning T, Kunimoto D, LeBlanc D, Johnson JA, Gray CA.

Can J Microbiol. 2010 Jun;56(6):487-94. doi: 10.1139/w10-035.

PMID:
20657619
29.

3'-bromo analogues of pyrimidine nucleosides as a new class of potent inhibitors of Mycobacterium tuberculosis.

Shakya N, Srivastav NC, Desroches N, Agrawal B, Kunimoto DY, Kumar R.

J Med Chem. 2010 May 27;53(10):4130-40. doi: 10.1021/jm100165w.

PMID:
20420370
30.

Pneumococcal pneumonia: potential for diagnosis through a urinary metabolic profile.

Slupsky CM, Rankin KN, Fu H, Chang D, Rowe BH, Charles PG, McGeer A, Low D, Long R, Kunimoto D, Sawyer MB, Fedorak RN, Adamko DJ, Saude EJ, Shah SL, Marrie TJ.

J Proteome Res. 2009 Dec;8(12):5550-8. doi: 10.1021/pr9006427.

PMID:
19817432
31.

Improving access to care by allowing self-referral to a hepatitis C clinic.

Doucette KE, Robson V, Shafran S, Kunimoto D.

Can J Gastroenterol. 2009 Jun;23(6):421-4.

32.

Use of the QuantiFERON-TB Gold test to confirm latent tuberculosis infection in a Canadian tuberculosis clinic.

Kunimoto D, Der E, Beckon A, Thomas L, Egedahl M, Beatch A, Williams G, Tyrrell G, Ahmed R, Brown N, Long R.

Int J Tuberc Lung Dis. 2009 Jun;13(6):726-30.

PMID:
19460248
33.

Acute multifocal posterior placoid pigment epitheliopathy (AMPPPE) mimicking migraine with aura.

Spencer BR Jr, Kunimoto DY, Patel DR, Dodick DW.

Cephalalgia. 2009 Jun;29(6):694-8. doi: 10.1111/j.1468-2982.2008.01797.x. Epub 2009 Feb 10. No abstract available.

PMID:
19220303
34.

Metallic intraocular foreign bodies: characteristics, interventions, and prognostic factors for visual outcome and globe survival.

Ehlers JP, Kunimoto DY, Ittoop S, Maguire JI, Ho AC, Regillo CD.

Am J Ophthalmol. 2008 Sep;146(3):427-433. doi: 10.1016/j.ajo.2008.05.021. Epub 2008 Jul 9.

PMID:
18614135
35.

Incidence of endophthalmitis after 20- and 25-gauge vitrectomy.

Kunimoto DY, Kaiser RS; Wills Eye Retina Service.

Ophthalmology. 2007 Dec;114(12):2133-7. Epub 2007 Oct 4.

PMID:
17916378
36.

Inhibition of Mycobacterium tuberculosis, Mycobacterium bovis, and Mycobacterium avium by novel dideoxy nucleosides.

Rai D, Johar M, Srivastav NC, Manning T, Agrawal B, Kunimoto DY, Kumar R.

J Med Chem. 2007 Sep 20;50(19):4766-74. Epub 2007 Aug 16.

PMID:
17696514
37.

Candidemia complicated by endophthalmitis: a prospective analysis.

Kannangara S, Shindler D, Kunimoto DY, Sell B, DeSimone JA.

Eur J Clin Microbiol Infect Dis. 2007 Nov;26(11):839-41. No abstract available.

PMID:
17668252
38.
39.

Studies on acyclic pyrimidines as inhibitors of mycobacteria.

Srivastav NC, Manning T, Kunimoto DY, Kumar R.

Bioorg Med Chem. 2007 Mar 1;15(5):2045-53. Epub 2006 Dec 23.

PMID:
17218105
40.

Endophthalmitis after open globe injury: microbiologic spectrum and susceptibilities of isolates.

Chhabra S, Kunimoto DY, Kazi L, Regillo CD, Ho AC, Belmont J, Maguire J, Vander J, Brown GC.

Am J Ophthalmol. 2006 Nov;142(5):852-4.

PMID:
17056367
42.

Design and studies of novel 5-substituted alkynylpyrimidine nucleosides as potent inhibitors of mycobacteria.

Rai D, Johar M, Manning T, Agrawal B, Kunimoto DY, Kumar R.

J Med Chem. 2005 Nov 3;48(22):7012-7.

PMID:
16250660
43.

Synthesis and in vitro anti-mycobacterial activity of 5-substituted pyrimidine nucleosides.

Johar M, Manning T, Kunimoto DY, Kumar R.

Bioorg Med Chem. 2005 Dec 15;13(24):6663-71. Epub 2005 Sep 1.

PMID:
16140016
44.

The lack of association between bacille Calmette-Guerin vaccination and clustering of Aboriginals with tuberculosis in western Canada.

Cook VJ, Hernández-Garduño E, Kunimoto D, Hershfield ES, Fanning EA, Hoeppner VH, Elwood RK, FitzGerald JM; Canadian Molecular Epidemiology of Tuberculosis Study Group.

Can Respir J. 2005 Apr;12(3):134-8.

45.

Relationship between clinical presentation and visual outcome in postoperative and posttraumatic endophthalmitis in south central India.

Das T, Kunimoto DY, Sharma S, Jalali S, Majji AB, Nagaraja Rao T, Gopinathan U, Athmanathan S; Endophthalmitis Research Group.

Indian J Ophthalmol. 2005 Mar;53(1):5-16.

46.

An infant with central nervous system complications of disseminated tuberculosis.

Mah JK, Kellner JD, Kunimoto D, Kaura D, Mah MW.

Can J Neurol Sci. 2005 Feb;32(1):112-4. No abstract available.

PMID:
15825557
47.

Tuberculosis: still overlooked as a cause of community-acquired pneumonia--how not to miss it.

Kunimoto D, Long R.

Respir Care Clin N Am. 2005 Mar;11(1):25-34. Review.

PMID:
15763219
48.

Transmission characteristics of tuberculosis in the foreign-born and the Canadian-born populations of Alberta, Canada.

Kunimoto D, Sutherland K, Wooldrage K, Fanning A, Chui L, Manfreda J, Long R.

Int J Tuberc Lung Dis. 2004 Oct;8(10):1213-20.

PMID:
15527153
49.

Transplantation in the face of severe donor sepsis: pushing the boundaries?

Pauly RP, Rayner D, Murray AG, Gilmour SM, Kunimoto DY.

Am J Kidney Dis. 2004 Oct;44(4):e64-7.

PMID:
15384036
50.

Pediatric tuberculosis in Alberta First Nations (1991-2000): outbreaks and the protective effect of bacille Calmette-Guérin (BCG) vaccine.

Long R, Whittaker D, Russell K, Kunimoto D, Reid R, Fanning A, Nobert E, Melenka L, Yacoub W, Bhargava R.

Can J Public Health. 2004 Jul-Aug;95(4):249-55.

PMID:
15362464

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