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Items: 29

1.

A novel, orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production, and goblet cell hyperplasia in animal models of pulmonary inflammation.

Chapman RW, Minnicozzi M, Celly CS, Phillips JE, Kung TT, Hipkin RW, Fan X, Rindgen D, Deno G, Bond R, Gonsiorek W, Billah MM, Fine JS, Hey JA.

J Pharmacol Exp Ther. 2007 Aug;322(2):486-93. Epub 2007 May 11.

PMID:
17496165
2.

A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo.

Lunn CA, Fine JS, Rojas-Triana A, Jackson JV, Fan X, Kung TT, Gonsiorek W, Schwarz MA, Lavey B, Kozlowski JA, Narula SK, Lundell DJ, Hipkin RW, Bober LA.

J Pharmacol Exp Ther. 2006 Feb;316(2):780-8. Epub 2005 Oct 28.

PMID:
16258021
3.

Tachykinin NK3-receptor deficiency does not inhibit pulmonary eosinophilia in allergic mice.

Kung TT, Crawley Y, Jones H, Luo B, Gilchrest H, Greenfeder S, Anthes JC, Lira S, Wiekowski M, Cook DN, Hey JA, Egan RW, Chapman RW.

Pharmacol Res. 2004 Dec;50(6):611-5.

PMID:
15501700
4.

Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor.

Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung TT, Crawley Y, Egan RW, Billah MM.

Biochem J. 2004 Jun 1;380(Pt 2):425-33.

5.

New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25.

Hurst SD, Muchamuel T, Gorman DM, Gilbert JM, Clifford T, Kwan S, Menon S, Seymour B, Jackson C, Kung TT, Brieland JK, Zurawski SM, Chapman RW, Zurawski G, Coffman RL.

J Immunol. 2002 Jul 1;169(1):443-53.

6.

Effect of anti-mIL-9 antibody on the development of pulmonary inflammation and airway hyperresponsiveness in allergic mice.

Kung TT, Luo B, Crawley Y, Garlisi CG, Devito K, Minnicozzi M, Egan RW, Kreutner W, Chapman RW.

Am J Respir Cell Mol Biol. 2001 Nov;25(5):600-5.

PMID:
11713102
7.

Comparison of PDE 4 inhibitors, rolipram and SB 207499 (ariflo), in a rat model of pulmonary neutrophilia.

Spond J, Chapman R, Fine J, Jones H, Kreutner W, Kung TT, Minnicozzi M.

Pulm Pharmacol Ther. 2001;14(2):157-64.

PMID:
11273798
8.
9.

Effect of Sch 55700, a humanized monoclonal antibody to human interleukin-5, on eosinophilic responses and bronchial hyperreactivity.

Egan RW, Athwal D, Bodmer MW, Carter JM, Chapman RW, Chou CC, Cox MA, Emtage JS, Fernandez X, Genatt N, Indelicato SR, Jenh CH, Kreutner W, Kung TT, Mauser PJ, Minnicozzi M, Murgolo NJ, Narula SK, Petro ME, Schilling A, Sehring S, Stelts D, Stephens S, Taremi SS, Zurcher J, et al.

Arzneimittelforschung. 1999 Sep;49(9):779-90.

PMID:
10514907
10.

Effects of cyclosporin A and dinactin on T-cell proliferation, interleukin-5 production, and murine pulmonary inflammation.

Umland SP, Shah H, Jakway JP, Shortall J, Razac S, Garlisi CG, Falcone A, Kung TT, Stelts D, Hegde V, Patel M, Motasim Billah M, Egan RW.

Am J Respir Cell Mol Biol. 1999 Mar;20(3):481-92.

PMID:
10030847
11.

Effects of chronic anti-interleukin-5 monoclonal antibody treatment in a murine model of pulmonary inflammation.

Garlisi CG, Kung TT, Wang P, Minnicozzi M, Umland SP, Chapman RW, Stelts D, Crawley Y, Falcone A, Myers JG, Jones H, Billah MM, Kreutner W, Egan RW.

Am J Respir Cell Mol Biol. 1999 Feb;20(2):248-55.

PMID:
9922215
12.

Anti-inflammatory activity of inhaled mometasone furoate in allergic mice.

Chapman RW, Sehring SJ, Garlisi CG, Falcone A, Kung TT, Stelts D, Minnicozzi M, Jones H, Umland S, Egan RW, Kreutner W.

Arzneimittelforschung. 1998 Apr;48(4):384-91.

PMID:
9608881
13.

Eosinophils retain their granule major basic protein in a murine model of allergic pulmonary inflammation.

Stelts D, Egan RW, Falcone A, Garlisi CG, Gleich GJ, Kreutner W, Kung TT, Nahrebne DK, Chapman RW, Minnicozzi M.

Am J Respir Cell Mol Biol. 1998 Apr;18(4):463-70.

PMID:
9533933
14.

Pulmonary eosinophilia and inflammation in allergic mice.

Kung TT.

Lab Anim Sci. 1998 Feb;48(1):61-3. No abstract available.

PMID:
9517892
15.

Role of nitric oxide on eosinophilic lung inflammation in allergic mice.

Feder LS, Stelts D, Chapman RW, Manfra D, Crawley Y, Jones H, Minnicozzi M, Fernandez X, Paster T, Egan RW, Kreutner W, Kung TT.

Am J Respir Cell Mol Biol. 1997 Oct;17(4):436-42.

PMID:
9376118
16.

Pulmonary biology of anti-interleukin 5 antibodies.

Egan RW, Athwahl D, Chou CC, Chapman RW, Emtage S, Jenh CH, Kung TT, Mauser PJ, Murgolo NJ, Bodmer MW.

Mem Inst Oswaldo Cruz. 1997;92 Suppl 2:69-73.

17.

Involvement of IL-5 in a murine model of allergic pulmonary inflammation: prophylactic and therapeutic effect of an anti-IL-5 antibody.

Kung TT, Stelts DM, Zurcher JA, Adams GK 3rd, Egan RW, Kreutner W, Watnick AS, Jones H, Chapman RW.

Am J Respir Cell Mol Biol. 1995 Sep;13(3):360-5.

PMID:
7654390
18.

Interferon-gamma and antibodies to interleukin-5 and interleukin-4 inhibit the pulmonary eosinophilia in allergic mice.

Kung TT, Stelts DM, Zurcher JA, Jones H, Umland SP, Egan RW, Kreutner W, Chapman RW.

Inflamm Res. 1995 Aug;44 Suppl 2:S185-6. No abstract available.

PMID:
8548389
19.

Inhibition of pulmonary eosinophilia and hyperreactivity by antibodies to interleukin-5.

Egan RW, Athwahl D, Chou CC, Emtage S, Jehn CH, Kung TT, Mauser PJ, Murgolo NJ, Bodmer MW.

Int Arch Allergy Immunol. 1995 May-Jun;107(1-3):321-2. Review.

20.

Mast cells modulate allergic pulmonary eosinophilia in mice.

Kung TT, Stelts D, Zurcher JA, Jones H, Umland SP, Kreutner W, Egan RW, Chapman RW.

Am J Respir Cell Mol Biol. 1995 Apr;12(4):404-9.

PMID:
7695919
21.

T cells are necessary for Th2 cytokine production and eosinophil accumulation in airways of antigen-challenged allergic mice.

Garlisi CG, Falcone A, Kung TT, Stelts D, Pennline KJ, Beavis AJ, Smith SR, Egan RW, Umland SP.

Clin Immunol Immunopathol. 1995 Apr;75(1):75-83.

PMID:
7533686
22.

Mechanisms of allergic pulmonary eosinophilia in the mouse.

Kung TT, Stelts D, Zurcher JA, Watnick AS, Jones H, Mauser PJ, Fernandez X, Umland S, Kreutner W, Chapman RW, et al.

J Allergy Clin Immunol. 1994 Dec;94(6 Pt 2):1217-24. No abstract available.

PMID:
7798563
23.

Characterization of a murine model of allergic pulmonary inflammation.

Kung TT, Jones H, Adams GK 3rd, Umland SP, Kreutner W, Egan RW, Chapman RW, Watnick AS.

Int Arch Allergy Immunol. 1994 Sep;105(1):83-90.

PMID:
8086833
24.
25.

Structure-activity relationships of a series of novel topical corticosteroids.

Popper TL, Gentles MJ, Kung TT, Berkenkopf J, Lutsky BN, Watnick AS, Shapiro EL.

J Steroid Biochem. 1987;27(4-6):837-43.

PMID:
3695507
26.

Novel 17 alpha-chloro-17 beta-sulfinyl steroids as specific inhibitors of sebaceous gland activity: potential antiacne agents.

Green MJ, Tiberi R, Draper RW, Carlon FE, Neri RO, Kung TT, McPhail AT, Onan KD.

J Med Chem. 1983 Jan;26(1):78-85.

PMID:
6219222
27.
28.

Effect of progesteroids on the cellular response to inflammation in the monkey.

Kung TT, Munroe JS.

J Reticuloendothel Soc. 1973 Jul;14(1):59-67. No abstract available.

PMID:
4200704
29.

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