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Items: 1 to 50 of 147

1.

The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis.

Singh S, Kumar M, Kumar S, Sen S, Upadhyay P, Bhattacharjee S, M N, Tomar VS, Roy S, Dutt A, Kundu TK.

J Biol Chem. 2019 Sep 20;294(38):14081-14095. doi: 10.1074/jbc.RA118.007265. Epub 2019 Jul 31.

PMID:
31366730
2.

Tumor Suppressor p53-Mediated Structural Reorganization of the Transcriptional Coactivator p300.

Ghosh R, Kaypee S, Shasmal M, Kundu TK, Roy S, Sengupta J.

Biochemistry. 2019 Aug 13;58(32):3434-3443. doi: 10.1021/acs.biochem.9b00333. Epub 2019 Jul 31.

PMID:
31314496
3.

Multifunctional transcriptional coactivator PC4 is a global co-regulator of p53-dependent stress response and gene regulation.

Mondal P, Saleem S, Sikder S, Kundu TK, Biswas SC, Roy S.

J Biochem. 2019 Jun 24. pii: mvz050. doi: 10.1093/jb/mvz050. [Epub ahead of print]

PMID:
31236588
4.

Functional interplay between YY1 and CARM1 promotes oral carcinogenesis.

Behera AK, Kumar M, Shanmugam MK, Bhattacharya A, Rao VJ, Bhat A, Vasudevan M, Gopinath KS, Mohiyuddin A, Chatterjee A, Sethi G, Kundu TK.

Oncotarget. 2019 Jun 4;10(38):3709-3724. doi: 10.18632/oncotarget.26984. eCollection 2019 Jun 4.

5.

Nonhistone human chromatin protein PC4 is critical for genomic integrity and negatively regulates autophagy.

Sikder S, Kumari S, Mustafi P, Ramdas N, Padhi S, Saha A, Bhaduri U, Banerjee B, Manjithaya R, Kundu TK.

FEBS J. 2019 Jun 6. doi: 10.1111/febs.14952. [Epub ahead of print]

PMID:
31169983
6.

Corrigendum: The Dietary Flavonoid, Luteolin, Negatively Affects Neuronal Differentiation.

Swaminathan A, Basu M, Bekri A, Drapeau P, Kundu TK.

Front Mol Neurosci. 2019 May 15;12:122. doi: 10.3389/fnmol.2019.00122. eCollection 2019.

7.

Nonbonding interaction analyses on PVDF/[BMIM][BF4] complex system in gas and solution phase.

Sarkar R, Kundu TK.

J Mol Model. 2019 Apr 25;25(5):131. doi: 10.1007/s00894-019-4020-9.

PMID:
31025122
8.

Allosteric Regulation of Cyclin-B Binding by the Charge State of Catalytic Lysine in CDK1 Is Essential for Cell-Cycle Progression.

Deota S, Rathnachalam S, Namrata K, Boob M, Fulzele A, Radhika S, Ganguli S, Balaji C, Kaypee S, Vishwakarma KK, Kundu TK, Bhandari R, Gonzalez de Peredo A, Mishra M, Venkatramani R, Kolthur-Seetharam U.

J Mol Biol. 2019 May 17;431(11):2127-2142. doi: 10.1016/j.jmb.2019.04.005. Epub 2019 Apr 9.

PMID:
30974121
9.

Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models.

Hutson TH, Kathe C, Palmisano I, Bartholdi K, Hervera A, De Virgiliis F, McLachlan E, Zhou L, Kong G, Barraud Q, Danzi MC, Medrano-Fernandez A, Lopez-Atalaya JP, Boutillier AL, Sinha SH, Singh AK, Chaturbedy P, Moon LDF, Kundu TK, Bixby JL, Lemmon VP, Barco A, Courtine G, Di Giovanni S.

Sci Transl Med. 2019 Apr 10;11(487). pii: eaaw2064. doi: 10.1126/scitranslmed.aaw2064.

10.

The Dietary Flavonoid, Luteolin, Negatively Affects Neuronal Differentiation.

Swaminathan A, Basu M, Bekri A, Drapeau P, Kundu TK.

Front Mol Neurosci. 2019 Mar 8;12:41. doi: 10.3389/fnmol.2019.00041. eCollection 2019. Erratum in: Front Mol Neurosci. 2019 May 15;12:122.

11.

Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator.

Chatterjee S, Cassel R, Schneider-Anthony A, Merienne K, Cosquer B, Tzeplaeff L, Halder Sinha S, Kumar M, Chaturbedy P, Eswaramoorthy M, Le Gras S, Keime C, Bousiges O, Dutar P, Petsophonsakul P, Rampon C, Cassel JC, Buée L, Blum D, Kundu TK, Boutillier AL.

EMBO Mol Med. 2018 Nov;10(11). pii: e8587. doi: 10.15252/emmm.201708587.

12.

Mutant and Wild-Type Tumor Suppressor p53 Induces p300 Autoacetylation.

Kaypee S, Sahadevan SA, Patil S, Ghosh P, Roy NS, Roy S, Kundu TK.

iScience. 2018 Jun 29;4:260-272. doi: 10.1016/j.isci.2018.06.002. Epub 2018 Jun 7.

13.

Oncogene c-fos and mutant R175H p53 regulate expression of Nucleophosmin implicating cancer manifestation.

Senapati P, Dey S, Sudarshan D, Das S, Kumar M, Kaypee S, Mohiyuddin A, Kodaganur GS, Kundu TK.

FEBS J. 2018 Sep;285(18):3503-3524. doi: 10.1111/febs.14625. Epub 2018 Aug 24.

14.

Unraveling the role of aurora A beyond centrosomes and spindle assembly: implications in muscle differentiation.

Dhanasekaran K, Bose A, Rao VJ, Boopathi R, Shankar SR, Rao VK, Swaminathan A, Vasudevan M, Taneja R, Kundu TK.

FASEB J. 2019 Jan;33(1):219-230. doi: 10.1096/fj.201800997. Epub 2018 Jul 11.

PMID:
29995440
15.

Evolution of genome organization and epigenetic machineries.

Kundu TK, Sikder S.

J Biosci. 2018 Jun;43(2):239-242. No abstract available.

16.

Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation.

Kaypee S, Sahadevan SA, Sudarshan D, Halder Sinha S, Patil S, Senapati P, Kodaganur GS, Mohiyuddin A, Dasgupta D, Kundu TK.

Biochim Biophys Acta Gen Subj. 2018 Aug;1862(8):1729-1741. doi: 10.1016/j.bbagen.2018.05.003. Epub 2018 May 8.

PMID:
29746960
17.

Epigenetic modulation by small molecule compounds for neurodegenerative disorders.

Singh AK, Halder-Sinha S, Clement JP, Kundu TK.

Pharmacol Res. 2018 Jun;132:135-148. doi: 10.1016/j.phrs.2018.04.014. Epub 2018 Apr 20. Review.

PMID:
29684672
18.

p53 mediated regulation of coactivator associated arginine methyltransferase 1 (CARM1) expression is critical for suppression of adipogenesis.

Behera AK, Bhattacharya A, Vasudevan M, Kundu TK.

FEBS J. 2018 May;285(9):1730-1744. doi: 10.1111/febs.14440. Epub 2018 Apr 17.

19.

Chemical and genetic rescue of an ep300 knockdown model for Rubinstein Taybi Syndrome in zebrafish.

Babu A, Kamaraj M, Basu M, Mukherjee D, Kapoor S, Ranjan S, Swamy MM, Kaypee S, Scaria V, Kundu TK, Sachidanandan C.

Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt A):1203-1215. doi: 10.1016/j.bbadis.2018.01.029. Epub 2018 Jan 31.

20.

An Exploratory Study of Autonomic Function Investigations in Hemophiliacs on Homoeopathy Medications Using Impedance Plethysmography.

Kundu TK, Barde PB, Jindal GD, Motiwala FF.

J Evid Based Complementary Altern Med. 2017 Oct;22(4):760-764. doi: 10.1177/2156587217718750. Epub 2017 Jul 18.

21.

Inhibition of histone/lysine acetyltransferase activity kills CoCl2-treated and hypoxia-exposed gastric cancer cells and reduces their invasiveness.

Rath S, Das L, Kokate SB, Ghosh N, Dixit P, Rout N, Singh SP, Chattopadhyay S, Ashktorab H, Smoot DT, Swamy MM, Kundu TK, Crowe SE, Bhattacharyya A.

Int J Biochem Cell Biol. 2017 Jan;82:28-40. doi: 10.1016/j.biocel.2016.11.014. Epub 2016 Nov 23.

22.

P/CAF mediates PAX3-FOXO1-dependent oncogenesis in alveolar rhabdomyosarcoma.

Bharathy N, Suriyamurthy S, Rao VK, Ow JR, Lim HJ, Chakraborty P, Vasudevan M, Dhamne CA, Chang KT, Min VL, Kundu TK, Taneja R.

J Pathol. 2016 Nov;240(3):269-281. doi: 10.1002/path.4773. Epub 2016 Sep 27.

PMID:
27453350
23.

Garcinol and Its Role in Chronic Diseases.

Behera AK, Swamy MM, Natesh N, Kundu TK.

Adv Exp Med Biol. 2016;928:435-452. Review.

PMID:
27671827
24.

Transcriptional Coactivator and Chromatin Protein PC4 Is Involved in Hippocampal Neurogenesis and Spatial Memory Extinction.

Swaminathan A, Delage H, Chatterjee S, Belgarbi-Dutron L, Cassel R, Martinez N, Cosquer B, Kumari S, Mongelard F, Lannes B, Cassel JC, Boutillier AL, Bouvet P, Kundu TK.

J Biol Chem. 2016 Sep 23;291(39):20303-14. doi: 10.1074/jbc.M116.744169. Epub 2016 Jul 28.

25.

14-3-3γ Prevents Centrosome Amplification and Neoplastic Progression.

Mukhopadhyay A, Sehgal L, Bose A, Gulvady A, Senapati P, Thorat R, Basu S, Bhatt K, Hosing AS, Balyan R, Borde L, Kundu TK, Dalal SN.

Sci Rep. 2016 Jun 2;6:26580. doi: 10.1038/srep26580.

26.

Functional Incompatibility between the Generic NF-κB Motif and a Subtype-Specific Sp1III Element Drives the Formation of the HIV-1 Subtype C Viral Promoter.

Verma A, Rajagopalan P, Lotke R, Varghese R, Selvam D, Kundu TK, Ranga U.

J Virol. 2016 Jul 27;90(16):7046-7065. doi: 10.1128/JVI.00308-16. Print 2016 Aug 15.

27.

A Dual Non-ATP Analogue Inhibitor of Aurora Kinases A and B, Derived from Resorcinol with a Mixed Mode of Inhibition.

Karthigeyan D, Surabhi S, Mizar P, Soumik S, Banerjee A, Sinha SH, Dasgupta D, Narayana C, Kundu TK.

Chem Biol Drug Des. 2016 Jun;87(6):958-67. doi: 10.1111/cbdd.12728. Epub 2016 Mar 21.

PMID:
26808391
28.

Aberrant lysine acetylation in tumorigenesis: Implications in the development of therapeutics.

Kaypee S, Sudarshan D, Shanmugam MK, Mukherjee D, Sethi G, Kundu TK.

Pharmacol Ther. 2016 Jun;162:98-119. doi: 10.1016/j.pharmthera.2016.01.011. Epub 2016 Jan 22. Review.

PMID:
26808162
29.

Multifunctional human transcriptional coactivator protein PC4 is a substrate of Aurora kinases and activates the Aurora enzymes.

Dhanasekaran K, Kumari S, Boopathi R, Shima H, Swaminathan A, Bachu M, Ranga U, Igarashi K, Kundu TK.

FEBS J. 2016 Mar;283(6):968-85. doi: 10.1111/febs.13653. Epub 2016 Feb 15.

30.

Roles for Transcription Factors Sp1, NF-κB, IRF3, and IRF7 in Expression of the Human IFNL4 Gene.

Chinnaswamy S, Bhushan A, Behera AK, Ghosh S, Rampurkar V, Chandra V, Pandit B, Kundu TK.

Viral Immunol. 2016 Jan-Feb;29(1):49-63. doi: 10.1089/vim.2015.0076. Epub 2015 Dec 18.

PMID:
26684959
31.

Inhibition of p300 lysine acetyltransferase activity by luteolin reduces tumor growth in head and neck squamous cell carcinoma (HNSCC) xenograft mouse model.

Selvi RB, Swaminathan A, Chatterjee S, Shanmugam MK, Li F, Ramakrishnan GB, Siveen KS, Chinnathambi A, Zayed ME, Alharbi SA, Basha J, Bhat A, Vasudevan M, Dharmarajan A, Sethi G, Kundu TK.

Oncotarget. 2015 Dec 22;6(41):43806-18. doi: 10.18632/oncotarget.6245.

32.

Shape-directed compartmentalized delivery of a nanoparticle-conjugated small-molecule activator of an epigenetic enzyme in the brain.

Chaturbedy P, Kumar M, Salikolimi K, Das S, Sinha SH, Chatterjee S, Suma BS, Kundu TK, Eswaramoorthy M.

J Control Release. 2015 Nov 10;217:151-9. doi: 10.1016/j.jconrel.2015.08.043. Epub 2015 Aug 29.

PMID:
26325406
33.

Methods to study histone chaperone function in nucleosome assembly and chromatin transcription.

Senapati P, Sudarshan D, Gadad SS, Shandilya J, Swaminathan V, Kundu TK.

Methods Mol Biol. 2015;1288:375-94. doi: 10.1007/978-1-4939-2474-5_22.

PMID:
25827892
34.

Identification and characterization of nonhistone chromatin proteins: human positive coactivator 4 as a candidate.

Kumari S, Das C, Sikder S, Kumar M, Bachu M, Ranga U, Kundu TK.

Methods Mol Biol. 2015;1288:245-72. doi: 10.1007/978-1-4939-2474-5_14.

PMID:
25827884
35.

A Constrained Helical Peptide Against S100A4 Inhibits Cell Motility in Tumor Cells.

Naiya G, Kaypee S, Kundu TK, Roy S.

Chem Biol Drug Des. 2015 Oct;86(4):945-50. doi: 10.1111/cbdd.12553. Epub 2015 Apr 15.

PMID:
25763457
36.

Hydrazinobenzoylcurcumin inhibits androgen receptor activity and growth of castration-resistant prostate cancer in mice.

Wu M, Kim SH, Datta I, Levin A, Dyson G, Li J, Kaypee S, Swamy MM, Gupta N, Kwon HJ, Menon M, Kundu TK, Reddy GP.

Oncotarget. 2015 Mar 20;6(8):6136-50.

37.

CARM1 regulates astroglial lineage through transcriptional regulation of Nanog and posttranscriptional regulation by miR92a.

Selvi BR, Swaminathan A, Maheshwari U, Nagabhushana A, Mishra RK, Kundu TK.

Mol Biol Cell. 2015 Jan 15;26(2):316-26. doi: 10.1091/mbc.E14-01-0019. Epub 2014 Nov 12.

38.

A thiazole coumarin (TC) turn-on fluorescence probe for AT-base pair detection and multipurpose applications in different biological systems.

Narayanaswamy N, Kumar M, Das S, Sharma R, Samanta PK, Pati SK, Dhar SK, Kundu TK, Govindaraju T.

Sci Rep. 2014 Sep 25;4:6476. doi: 10.1038/srep06476.

39.

Histone H3K9 acetylation level modulates gene expression and may affect parasite growth in human malaria parasite Plasmodium falciparum.

Srivastava S, Bhowmick K, Chatterjee S, Basha J, Kundu TK, Dhar SK.

FEBS J. 2014 Dec;281(23):5265-78. doi: 10.1111/febs.13067. Epub 2014 Oct 13.

40.

Modulation of neurogenesis by targeting epigenetic enzymes using small molecules: an overview.

Swaminathan A, Kumar M, Halder Sinha S, Schneider-Anthony A, Boutillier AL, Kundu TK.

ACS Chem Neurosci. 2014 Dec 17;5(12):1164-77. doi: 10.1021/cn500117a. Epub 2014 Oct 10. Review.

PMID:
25250644
41.

Promoter-proximal transcription factor binding is transcriptionally active when coupled with nucleosome repositioning in immediate vicinity.

Yadav VK, Thakur RK, Eckloff B, Baral A, Singh A, Halder R, Kumar A, Alam MP, Kundu TK, Pandita R, Pandita TK, Wieben ED, Chowdhury S.

Nucleic Acids Res. 2014 Sep;42(15):9602-11. doi: 10.1093/nar/gku596. Epub 2014 Jul 31.

42.

Epigenetic response in mice mastitis: Role of histone H3 acetylation and microRNA(s) in the regulation of host inflammatory gene expression during Staphylococcus aureus infection.

Modak R, Das Mitra S, Vasudevan M, Krishnamoorthy P, Kumar M, Bhat AV, Bhuvana M, Ghosh SK, Shome BR, Kundu TK.

Clin Epigenetics. 2014 Jun 30;6(1):12. doi: 10.1186/1868-7083-6-12. eCollection 2014.

43.

High-glucose-induced CARM1 expression regulates apoptosis of human retinal pigment epithelial cells via histone 3 arginine 17 dimethylation: role in diabetic retinopathy.

Kim DI, Park MJ, Lim SK, Choi JH, Kim JC, Han HJ, Kundu TK, Park JI, Yoon KC, Park SW, Park JS, Heo YR, Park SH.

Arch Biochem Biophys. 2014 Oct 15;560:36-43. doi: 10.1016/j.abb.2014.07.021. Epub 2014 Jul 27.

PMID:
25072916
44.

Drug discovery research in India: current state and future prospects.

Balganesh T, Kundu TK, Chakraborty TK, Roy S.

ACS Med Chem Lett. 2014 May 23;5(7):724-6. doi: 10.1021/ml500183c. eCollection 2014 Jul 10.

45.

SERS and MD simulation studies of a kinase inhibitor demonstrate the emergence of a potential drug discovery tool.

Karthigeyan D, Siddhanta S, Kishore AH, Perumal SS, Ågren H, Sudevan S, Bhat AV, Balasubramanyam K, Subbegowda RK, Kundu TK, Narayana C.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10416-21. doi: 10.1073/pnas.1402695111. Epub 2014 Jun 27.

46.

Phosphorylation of multifunctional nucleolar protein nucleophosmin (NPM1) by aurora kinase B is critical for mitotic progression.

Shandilya J, Senapati P, Dhanasekaran K, Bangalore SS, Kumar M, Kishore AH, Bhat A, Kodaganur GS, Kundu TK.

FEBS Lett. 2014 Jun 27;588(14):2198-205. doi: 10.1016/j.febslet.2014.05.014. Epub 2014 May 21.

47.

Centromeric histone variant CENP-A represses acetylation-dependent chromatin transcription that is relieved by histone chaperone NPM1.

Shandilya J, Senapati P, Hans F, Menoni H, Bouvet P, Dimitrov S, Angelov D, Kundu TK.

J Biochem. 2014 Oct;156(4):221-7. doi: 10.1093/jb/mvu034. Epub 2014 May 16.

PMID:
24839294
48.

Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo.

Sethi G, Chatterjee S, Rajendran P, Li F, Shanmugam MK, Wong KF, Kumar AP, Senapati P, Behera AK, Hui KM, Basha J, Natesh N, Luk JM, Kundu TK.

Mol Cancer. 2014 Mar 21;13:66. doi: 10.1186/1476-4598-13-66.

49.

Gene regulatory networks and epigenetic modifications in cell differentiation.

Roy S, Kundu TK.

IUBMB Life. 2014 Feb;66(2):100-9. doi: 10.1002/iub.1249. Epub 2014 Feb 27. Review.

50.

Naphthoquinone-mediated inhibition of lysine acetyltransferase KAT3B/p300, basis for non-toxic inhibitor synthesis.

Vasudevarao MD, Mizar P, Kumari S, Mandal S, Siddhanta S, Swamy MM, Kaypee S, Kodihalli RC, Banerjee A, Naryana C, Dasgupta D, Kundu TK.

J Biol Chem. 2014 Mar 14;289(11):7702-17. doi: 10.1074/jbc.M113.486522. Epub 2014 Jan 27.

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