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Items: 1 to 50 of 137

1.

Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator.

Chatterjee S, Cassel R, Schneider-Anthony A, Merienne K, Cosquer B, Tzeplaeff L, Halder Sinha S, Kumar M, Chaturbedy P, Eswaramoorthy M, Le Gras S, Keime C, Bousiges O, Dutar P, Petsophonsakul P, Rampon C, Cassel JC, Buée L, Blum D, Kundu TK, Boutillier AL.

EMBO Mol Med. 2018 Oct 1. pii: e8587. doi: 10.15252/emmm.201708587. [Epub ahead of print]

2.

Mutant and Wild-Type Tumor Suppressor p53 Induces p300 Autoacetylation.

Kaypee S, Sahadevan SA, Patil S, Ghosh P, Roy NS, Roy S, Kundu TK.

iScience. 2018 Jun 29;4:260-272. doi: 10.1016/j.isci.2018.06.002. Epub 2018 Jun 7.

3.

Oncogene c-fos and mutant R175H p53 regulate expression of Nucleophosmin implicating cancer manifestation.

Senapati P, Dey S, Sudarshan D, Das S, Kumar M, Kaypee S, Mohiyuddin A, Kodaganur GS, Kundu TK.

FEBS J. 2018 Sep;285(18):3503-3524. doi: 10.1111/febs.14625. Epub 2018 Aug 24.

PMID:
30085406
4.

Unraveling the role of aurora A beyond centrosomes and spindle assembly: implications in muscle differentiation.

Dhanasekaran K, Bose A, Rao VJ, Boopathi R, Shankar SR, Rao VK, Swaminathan A, Vasudevan M, Taneja R, Kundu TK.

FASEB J. 2018 Jul 11:fj201800997. doi: 10.1096/fj.201800997. [Epub ahead of print]

PMID:
29995440
5.

Evolution of genome organization and epigenetic machineries.

Kundu TK, Sikder S.

J Biosci. 2018 Jun;43(2):239-242. No abstract available.

6.

Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation.

Kaypee S, Sahadevan SA, Sudarshan D, Halder Sinha S, Patil S, Senapati P, Kodaganur GS, Mohiyuddin A, Dasgupta D, Kundu TK.

Biochim Biophys Acta Gen Subj. 2018 Aug;1862(8):1729-1741. doi: 10.1016/j.bbagen.2018.05.003. Epub 2018 May 8.

PMID:
29746960
7.

Epigenetic modulation by small molecule compounds for neurodegenerative disorders.

Singh AK, Halder-Sinha S, Clement JP, Kundu TK.

Pharmacol Res. 2018 Jun;132:135-148. doi: 10.1016/j.phrs.2018.04.014. Epub 2018 Apr 20. Review.

PMID:
29684672
8.

p53 mediated regulation of coactivator associated arginine methyltransferase 1 (CARM1) expression is critical for suppression of adipogenesis.

Behera AK, Bhattacharya A, Vasudevan M, Kundu TK.

FEBS J. 2018 May;285(9):1730-1744. doi: 10.1111/febs.14440. Epub 2018 Apr 17.

PMID:
29575726
9.

Chemical and genetic rescue of an ep300 knockdown model for Rubinstein Taybi Syndrome in zebrafish.

Babu A, Kamaraj M, Basu M, Mukherjee D, Kapoor S, Ranjan S, Swamy MM, Kaypee S, Scaria V, Kundu TK, Sachidanandan C.

Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt A):1203-1215. doi: 10.1016/j.bbadis.2018.01.029. Epub 2018 Jan 31.

PMID:
29409755
10.

An Exploratory Study of Autonomic Function Investigations in Hemophiliacs on Homoeopathy Medications Using Impedance Plethysmography.

Kundu TK, Barde PB, Jindal GD, Motiwala FF.

J Evid Based Complementary Altern Med. 2017 Oct;22(4):760-764. doi: 10.1177/2156587217718750. Epub 2017 Jul 18.

11.

Inhibition of histone/lysine acetyltransferase activity kills CoCl2-treated and hypoxia-exposed gastric cancer cells and reduces their invasiveness.

Rath S, Das L, Kokate SB, Ghosh N, Dixit P, Rout N, Singh SP, Chattopadhyay S, Ashktorab H, Smoot DT, Swamy MM, Kundu TK, Crowe SE, Bhattacharyya A.

Int J Biochem Cell Biol. 2017 Jan;82:28-40. doi: 10.1016/j.biocel.2016.11.014. Epub 2016 Nov 23.

12.

P/CAF mediates PAX3-FOXO1-dependent oncogenesis in alveolar rhabdomyosarcoma.

Bharathy N, Suriyamurthy S, Rao VK, Ow JR, Lim HJ, Chakraborty P, Vasudevan M, Dhamne CA, Chang KT, Min VL, Kundu TK, Taneja R.

J Pathol. 2016 Nov;240(3):269-281. doi: 10.1002/path.4773. Epub 2016 Sep 27.

PMID:
27453350
13.

Garcinol and Its Role in Chronic Diseases.

Behera AK, Swamy MM, Natesh N, Kundu TK.

Adv Exp Med Biol. 2016;928:435-452. Review.

PMID:
27671827
14.

Transcriptional Coactivator and Chromatin Protein PC4 Is Involved in Hippocampal Neurogenesis and Spatial Memory Extinction.

Swaminathan A, Delage H, Chatterjee S, Belgarbi-Dutron L, Cassel R, Martinez N, Cosquer B, Kumari S, Mongelard F, Lannes B, Cassel JC, Boutillier AL, Bouvet P, Kundu TK.

J Biol Chem. 2016 Sep 23;291(39):20303-14. doi: 10.1074/jbc.M116.744169. Epub 2016 Jul 28.

15.

14-3-3γ Prevents Centrosome Amplification and Neoplastic Progression.

Mukhopadhyay A, Sehgal L, Bose A, Gulvady A, Senapati P, Thorat R, Basu S, Bhatt K, Hosing AS, Balyan R, Borde L, Kundu TK, Dalal SN.

Sci Rep. 2016 Jun 2;6:26580. doi: 10.1038/srep26580.

16.

Functional Incompatibility between the Generic NF-κB Motif and a Subtype-Specific Sp1III Element Drives the Formation of the HIV-1 Subtype C Viral Promoter.

Verma A, Rajagopalan P, Lotke R, Varghese R, Selvam D, Kundu TK, Ranga U.

J Virol. 2016 Jul 27;90(16):7046-7065. doi: 10.1128/JVI.00308-16. Print 2016 Aug 15.

17.

A Dual Non-ATP Analogue Inhibitor of Aurora Kinases A and B, Derived from Resorcinol with a Mixed Mode of Inhibition.

Karthigeyan D, Surabhi S, Mizar P, Soumik S, Banerjee A, Sinha SH, Dasgupta D, Narayana C, Kundu TK.

Chem Biol Drug Des. 2016 Jun;87(6):958-67. doi: 10.1111/cbdd.12728. Epub 2016 Mar 21.

PMID:
26808391
18.

Aberrant lysine acetylation in tumorigenesis: Implications in the development of therapeutics.

Kaypee S, Sudarshan D, Shanmugam MK, Mukherjee D, Sethi G, Kundu TK.

Pharmacol Ther. 2016 Jun;162:98-119. doi: 10.1016/j.pharmthera.2016.01.011. Epub 2016 Jan 22. Review.

PMID:
26808162
19.

Multifunctional human transcriptional coactivator protein PC4 is a substrate of Aurora kinases and activates the Aurora enzymes.

Dhanasekaran K, Kumari S, Boopathi R, Shima H, Swaminathan A, Bachu M, Ranga U, Igarashi K, Kundu TK.

FEBS J. 2016 Mar;283(6):968-85. doi: 10.1111/febs.13653. Epub 2016 Feb 15.

20.

Roles for Transcription Factors Sp1, NF-κB, IRF3, and IRF7 in Expression of the Human IFNL4 Gene.

Chinnaswamy S, Bhushan A, Behera AK, Ghosh S, Rampurkar V, Chandra V, Pandit B, Kundu TK.

Viral Immunol. 2016 Jan-Feb;29(1):49-63. doi: 10.1089/vim.2015.0076. Epub 2015 Dec 18.

PMID:
26684959
21.

Inhibition of p300 lysine acetyltransferase activity by luteolin reduces tumor growth in head and neck squamous cell carcinoma (HNSCC) xenograft mouse model.

Selvi RB, Swaminathan A, Chatterjee S, Shanmugam MK, Li F, Ramakrishnan GB, Siveen KS, Chinnathambi A, Zayed ME, Alharbi SA, Basha J, Bhat A, Vasudevan M, Dharmarajan A, Sethi G, Kundu TK.

Oncotarget. 2015 Dec 22;6(41):43806-18. doi: 10.18632/oncotarget.6245.

22.

Shape-directed compartmentalized delivery of a nanoparticle-conjugated small-molecule activator of an epigenetic enzyme in the brain.

Chaturbedy P, Kumar M, Salikolimi K, Das S, Sinha SH, Chatterjee S, Suma BS, Kundu TK, Eswaramoorthy M.

J Control Release. 2015 Nov 10;217:151-9. doi: 10.1016/j.jconrel.2015.08.043. Epub 2015 Aug 29.

PMID:
26325406
23.

Methods to study histone chaperone function in nucleosome assembly and chromatin transcription.

Senapati P, Sudarshan D, Gadad SS, Shandilya J, Swaminathan V, Kundu TK.

Methods Mol Biol. 2015;1288:375-94. doi: 10.1007/978-1-4939-2474-5_22.

PMID:
25827892
24.

Identification and characterization of nonhistone chromatin proteins: human positive coactivator 4 as a candidate.

Kumari S, Das C, Sikder S, Kumar M, Bachu M, Ranga U, Kundu TK.

Methods Mol Biol. 2015;1288:245-72. doi: 10.1007/978-1-4939-2474-5_14.

PMID:
25827884
25.

A Constrained Helical Peptide Against S100A4 Inhibits Cell Motility in Tumor Cells.

Naiya G, Kaypee S, Kundu TK, Roy S.

Chem Biol Drug Des. 2015 Oct;86(4):945-50. doi: 10.1111/cbdd.12553. Epub 2015 Apr 15.

PMID:
25763457
26.

Hydrazinobenzoylcurcumin inhibits androgen receptor activity and growth of castration-resistant prostate cancer in mice.

Wu M, Kim SH, Datta I, Levin A, Dyson G, Li J, Kaypee S, Swamy MM, Gupta N, Kwon HJ, Menon M, Kundu TK, Reddy GP.

Oncotarget. 2015 Mar 20;6(8):6136-50.

27.

CARM1 regulates astroglial lineage through transcriptional regulation of Nanog and posttranscriptional regulation by miR92a.

Selvi BR, Swaminathan A, Maheshwari U, Nagabhushana A, Mishra RK, Kundu TK.

Mol Biol Cell. 2015 Jan 15;26(2):316-26. doi: 10.1091/mbc.E14-01-0019. Epub 2014 Nov 12.

28.

A thiazole coumarin (TC) turn-on fluorescence probe for AT-base pair detection and multipurpose applications in different biological systems.

Narayanaswamy N, Kumar M, Das S, Sharma R, Samanta PK, Pati SK, Dhar SK, Kundu TK, Govindaraju T.

Sci Rep. 2014 Sep 25;4:6476. doi: 10.1038/srep06476.

29.

Histone H3K9 acetylation level modulates gene expression and may affect parasite growth in human malaria parasite Plasmodium falciparum.

Srivastava S, Bhowmick K, Chatterjee S, Basha J, Kundu TK, Dhar SK.

FEBS J. 2014 Dec;281(23):5265-78. doi: 10.1111/febs.13067. Epub 2014 Oct 13.

30.

Modulation of neurogenesis by targeting epigenetic enzymes using small molecules: an overview.

Swaminathan A, Kumar M, Halder Sinha S, Schneider-Anthony A, Boutillier AL, Kundu TK.

ACS Chem Neurosci. 2014 Dec 17;5(12):1164-77. doi: 10.1021/cn500117a. Epub 2014 Oct 10. Review.

PMID:
25250644
31.

Promoter-proximal transcription factor binding is transcriptionally active when coupled with nucleosome repositioning in immediate vicinity.

Yadav VK, Thakur RK, Eckloff B, Baral A, Singh A, Halder R, Kumar A, Alam MP, Kundu TK, Pandita R, Pandita TK, Wieben ED, Chowdhury S.

Nucleic Acids Res. 2014 Sep;42(15):9602-11. doi: 10.1093/nar/gku596. Epub 2014 Jul 31.

32.

Epigenetic response in mice mastitis: Role of histone H3 acetylation and microRNA(s) in the regulation of host inflammatory gene expression during Staphylococcus aureus infection.

Modak R, Das Mitra S, Vasudevan M, Krishnamoorthy P, Kumar M, Bhat AV, Bhuvana M, Ghosh SK, Shome BR, Kundu TK.

Clin Epigenetics. 2014 Jun 30;6(1):12. doi: 10.1186/1868-7083-6-12. eCollection 2014.

33.

High-glucose-induced CARM1 expression regulates apoptosis of human retinal pigment epithelial cells via histone 3 arginine 17 dimethylation: role in diabetic retinopathy.

Kim DI, Park MJ, Lim SK, Choi JH, Kim JC, Han HJ, Kundu TK, Park JI, Yoon KC, Park SW, Park JS, Heo YR, Park SH.

Arch Biochem Biophys. 2014 Oct 15;560:36-43. doi: 10.1016/j.abb.2014.07.021. Epub 2014 Jul 27.

PMID:
25072916
34.

Drug discovery research in India: current state and future prospects.

Balganesh T, Kundu TK, Chakraborty TK, Roy S.

ACS Med Chem Lett. 2014 May 23;5(7):724-6. doi: 10.1021/ml500183c. eCollection 2014 Jul 10.

35.

SERS and MD simulation studies of a kinase inhibitor demonstrate the emergence of a potential drug discovery tool.

Karthigeyan D, Siddhanta S, Kishore AH, Perumal SS, Ågren H, Sudevan S, Bhat AV, Balasubramanyam K, Subbegowda RK, Kundu TK, Narayana C.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10416-21. doi: 10.1073/pnas.1402695111. Epub 2014 Jun 27.

36.

Phosphorylation of multifunctional nucleolar protein nucleophosmin (NPM1) by aurora kinase B is critical for mitotic progression.

Shandilya J, Senapati P, Dhanasekaran K, Bangalore SS, Kumar M, Kishore AH, Bhat A, Kodaganur GS, Kundu TK.

FEBS Lett. 2014 Jun 27;588(14):2198-205. doi: 10.1016/j.febslet.2014.05.014. Epub 2014 May 21.

37.

Centromeric histone variant CENP-A represses acetylation-dependent chromatin transcription that is relieved by histone chaperone NPM1.

Shandilya J, Senapati P, Hans F, Menoni H, Bouvet P, Dimitrov S, Angelov D, Kundu TK.

J Biochem. 2014 Oct;156(4):221-7. doi: 10.1093/jb/mvu034. Epub 2014 May 16.

PMID:
24839294
38.

Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo.

Sethi G, Chatterjee S, Rajendran P, Li F, Shanmugam MK, Wong KF, Kumar AP, Senapati P, Behera AK, Hui KM, Basha J, Natesh N, Luk JM, Kundu TK.

Mol Cancer. 2014 Mar 21;13:66. doi: 10.1186/1476-4598-13-66.

39.

Gene regulatory networks and epigenetic modifications in cell differentiation.

Roy S, Kundu TK.

IUBMB Life. 2014 Feb;66(2):100-9. doi: 10.1002/iub.1249. Epub 2014 Feb 27. Review.

40.

Naphthoquinone-mediated inhibition of lysine acetyltransferase KAT3B/p300, basis for non-toxic inhibitor synthesis.

Vasudevarao MD, Mizar P, Kumari S, Mandal S, Siddhanta S, Swamy MM, Kaypee S, Kodihalli RC, Banerjee A, Naryana C, Dasgupta D, Kundu TK.

J Biol Chem. 2014 Mar 14;289(11):7702-17. doi: 10.1074/jbc.M113.486522. Epub 2014 Jan 27.

41.

A single nucleotide polymorphism associated with hepatitis C virus infections located in the distal region of the IL28B promoter influences NF-κB-mediated gene transcription.

Chinnaswamy S, Chatterjee S, Boopathi R, Mukherjee S, Bhattacharjee S, Kundu TK.

PLoS One. 2013 Oct 8;8(10):e75495. doi: 10.1371/journal.pone.0075495. eCollection 2013.

42.

Acetyltransferases (HATs) as targets for neurological therapeutics.

Schneider A, Chatterjee S, Bousiges O, Selvi BR, Swaminathan A, Cassel R, Blanc F, Kundu TK, Boutillier AL.

Neurotherapeutics. 2013 Oct;10(4):568-88. doi: 10.1007/s13311-013-0204-7. Review.

43.

Evident stabilization of the clinical profile in HIV/AIDS as evaluated in an open label clinical trial using a polyherbal formulation.

Asokan M, Lone IN, Mukthey AB, Siddhartha P, Mariappa G, Kotehal PK, Satish B, Wilson E, Sahayam S, Velayutham G, Perumal R, Baskaran K, Rengarajan D, Muthusamy R, Philip M, Ravindra KC, Basha JN, Mizar P, Kaur G, Mehra NK, Kundu TK, Subbakrishna DK, Satish KS, Ranga U.

Indian J Med Res. 2013 Jun;137(6):1128-44.

44.

A novel activator of CBP/p300 acetyltransferases promotes neurogenesis and extends memory duration in adult mice.

Chatterjee S, Mizar P, Cassel R, Neidl R, Selvi BR, Mohankrishna DV, Vedamurthy BM, Schneider A, Bousiges O, Mathis C, Cassel JC, Eswaramoorthy M, Kundu TK, Boutillier AL.

J Neurosci. 2013 Jun 26;33(26):10698-712. doi: 10.1523/JNEUROSCI.5772-12.2013.

45.

Garcinol, a polyisoprenylated benzophenone modulates multiple proinflammatory signaling cascades leading to the suppression of growth and survival of head and neck carcinoma.

Li F, Shanmugam MK, Chen L, Chatterjee S, Basha J, Kumar AP, Kundu TK, Sethi G.

Cancer Prev Res (Phila). 2013 Aug;6(8):843-54. doi: 10.1158/1940-6207.CAPR-13-0070. Epub 2013 Jun 26.

46.

Probing p300/CBP associated factor (PCAF)-dependent pathways with a small molecule inhibitor.

Modak R, Basha J, Bharathy N, Maity K, Mizar P, Bhat AV, Vasudevan M, Rao VK, Kok WK, Natesh N, Taneja R, Kundu TK.

ACS Chem Biol. 2013;8(6):1311-23. doi: 10.1021/cb4000597. Epub 2013 May 9.

PMID:
23570531
47.

International symposium on challenges in chemical biology: toward the formation of Chemical Biology Society of India.

Kundu TK, Jaisankar P, Roy S.

ACS Chem Biol. 2013 Apr 19;8(4):658-61. doi: 10.1021/cb4001876. Epub 2013 Apr 5. No abstract available.

PMID:
23560637
48.

Minor groove binder distamycin remodels chromatin but inhibits transcription.

Majumder P, Banerjee A, Shandilya J, Senapati P, Chatterjee S, Kundu TK, Dasgupta D.

PLoS One. 2013;8(2):e57693. doi: 10.1371/journal.pone.0057693. Epub 2013 Feb 27.

49.

Analysis of protein acetyltransferase structure-function relation by surface-enhanced raman scattering (SERS): a tool to screen and characterize small molecule modulators.

Arif M, Karthigeyan D, Siddhanta S, Kumar GV, Narayana C, Kundu TK.

Methods Mol Biol. 2013;981:239-61. doi: 10.1007/978-1-62703-305-3_19.

PMID:
23381867
50.

Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells.

Collins HM, Abdelghany MK, Messmer M, Yue B, Deeves SE, Kindle KB, Mantelingu K, Aslam A, Winkler GS, Kundu TK, Heery DM.

BMC Cancer. 2013 Jan 29;13:37. doi: 10.1186/1471-2407-13-37.

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