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Items: 38

1.

Impedance Control Strategies for Enhancing Sloped and Level Walking Capabilities for Individuals with Transfemoral Amputation Using a Powered Multi-Joint Prosthesis.

Bhakta K, Camargo J, Kunapuli P, Childers L, Young A.

Mil Med. 2020 Jan 7;185(Supplement_1):490-499. doi: 10.1093/milmed/usz229.

PMID:
32074296

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2.

Electromyography (EMG) Signal Contributions in Speed and Slope Estimation Using Robotic Exoskeletons.

Kang I, Kunapuli P, Hsu H, Young AJ.

IEEE Int Conf Rehabil Robot. 2019 Jun;2019:548-553. doi: 10.1109/ICORR.2019.8779433.

PMID:
31374687

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3.

Discovery of PDK1 kinase inhibitors with a novel mechanism of action by ultrahigh throughput screening.

Bobkova EV, Weber MJ, Xu Z, Zhang YL, Jung J, Blume-Jensen P, Northrup A, Kunapuli P, Andersen JN, Kariv I.

J Biol Chem. 2010 Jun 11;285(24):18838-46. doi: 10.1074/jbc.M109.089946. Epub 2010 Apr 12.

PMID:
20385558
Free PMC Article

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4.

Reexpression of LGI1 in glioma cells results in dysregulation of genes implicated in the canonical axon guidance pathway.

Kunapuli P, Lo K, Hawthorn L, Cowell JK.

Genomics. 2010 Feb;95(2):93-100. doi: 10.1016/j.ygeno.2009.10.001. Epub 2009 Oct 14.

PMID:
19835947
Free PMC Article

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5.

Inactivation of LGI1 expression accompanies early stage hyperplasia of prostate epithelium in the TRAMP murine model of prostate cancer.

Cowell JK, Head K, Kunapuli P, Vaughan M, Karasik E, Foster B.

Exp Mol Pathol. 2010 Feb;88(1):77-81. doi: 10.1016/j.yexmp.2009.09.008. Epub 2009 Sep 22.

PMID:
19778537
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6.

Mass spectrometry identifies LGI1-interacting proteins that are involved in synaptic vesicle function in the human brain.

Kunapuli P, Jang GF, Kazim L, Cowell JK.

J Mol Neurosci. 2009 Sep;39(1-2):137-43. doi: 10.1007/s12031-009-9202-y. Epub 2009 Apr 23.

PMID:
19387870

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7.

A combination of ultrahigh throughput PathHunter and cytokine secretion assays to identify glucocorticoid receptor agonists.

Patel A, Murray J, McElwee-Whitmer S, Bai C, Kunapuli P, Johnson EN.

Anal Biochem. 2009 Feb 15;385(2):286-92. doi: 10.1016/j.ab.2008.11.005. Epub 2008 Nov 11.

PMID:
19032930

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8.

Hit selection with false discovery rate control in genome-scale RNAi screens.

Zhang XD, Kuan PF, Ferrer M, Shu X, Liu YC, Gates AT, Kunapuli P, Stec EM, Xu M, Marine SD, Holder DJ, Strulovici B, Heyse JF, Espeseth AS.

Nucleic Acids Res. 2008 Aug;36(14):4667-79. doi: 10.1093/nar/gkn435. Epub 2008 Jul 15.

PMID:
18628291
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9.

A 1,536-well [(35)S]GTPgammaS scintillation proximity binding assay for ultra-high-throughput screening of an orphan galphai-coupled GPCR.

Johnson EN, Shi X, Cassaday J, Ferrer M, Strulovici B, Kunapuli P.

Assay Drug Dev Technol. 2008 Jun;6(3):327-37. doi: 10.1089/adt.2007.113.

PMID:
18537464

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10.

Integrating experimental and analytic approaches to improve data quality in genome-wide RNAi screens.

Zhang XD, Espeseth AS, Johnson EN, Chin J, Gates A, Mitnaul LJ, Marine SD, Tian J, Stec EM, Kunapuli P, Holder DJ, Heyse JF, Strulovici B, Ferrer M.

J Biomol Screen. 2008 Jun;13(5):378-89. doi: 10.1177/1087057108317145. Epub 2008 May 14.

PMID:
18480473

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11.

HSPA1A is an important regulator of the stability and function of ZNF198 and its oncogenic derivative, ZNF198-FGFR1.

Kasyapa CS, Kunapuli P, Cowell JK.

J Cell Biochem. 2007 Dec 1;102(5):1308-17.

PMID:
17471537

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12.

Ultra-high-throughput screening for antagonists of a Gi-coupled receptor in a 2.2-microl 3,456-well plate format cyclicAMP assay.

Weber M, Muthusubramaniam L, Murray J, Hudak E, Kornienko O, Johnson EN, Strulovici B, Kunapuli P.

Assay Drug Dev Technol. 2007 Feb;5(1):117-25.

PMID:
17355204

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13.

Arsenic trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation.

Wetzler M, Brady MT, Tracy E, Li ZR, Donohue KA, O'Loughlin KL, Cheng Y, Mortazavi A, McDonald AA, Kunapuli P, Wallace PK, Baer MR, Cowell JK, Baumann H.

Clin Cancer Res. 2006 Nov 15;12(22):6817-25.

PMID:
17121903
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14.

Cell imaging assays for G protein-coupled receptor internalization: application to high-throughput screening.

Lee S, Howell B, Kunapuli P.

Methods Enzymol. 2006;414:79-98.

PMID:
17110188

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15.

ZNF198, a zinc finger protein rearranged in myeloproliferative disease, localizes to the PML nuclear bodies and interacts with SUMO-1 and PML.

Kunapuli P, Kasyapa CS, Chin SF, Caldas C, Cowell JK.

Exp Cell Res. 2006 Nov 15;312(19):3739-51. Epub 2006 Aug 14.

PMID:
17027752

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16.

Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions.

Bartz SR, Zhang Z, Burchard J, Imakura M, Martin M, Palmieri A, Needham R, Guo J, Gordon M, Chung N, Warrener P, Jackson AL, Carleton M, Oatley M, Locco L, Santini F, Smith T, Kunapuli P, Ferrer M, Strulovici B, Friend SH, Linsley PS.

Mol Cell Biol. 2006 Dec;26(24):9377-86. Epub 2006 Sep 25.

PMID:
17000754
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17.

Robust statistical methods for hit selection in RNA interference high-throughput screening experiments.

Zhang XD, Yang XC, Chung N, Gates A, Stec E, Kunapuli P, Holder DJ, Ferrer M, Espeseth AS.

Pharmacogenomics. 2006 Apr;7(3):299-309.

PMID:
16610941

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18.

Non-peptide calcitonin gene-related peptide receptor antagonists from a benzodiazepinone lead.

Williams TM, Stump CA, Nguyen DN, Quigley AG, Bell IM, Gallicchio SN, Zartman CB, Wan BL, Penna KD, Kunapuli P, Kane SA, Koblan KS, Mosser SD, Rutledge RZ, Salvatore C, Fay JF, Vacca JP, Graham SL.

Bioorg Med Chem Lett. 2006 May 15;16(10):2595-8. Epub 2006 Mar 9.

PMID:
16527483

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19.

Identification of small molecule antagonists of the human mas-related gene-X1 receptor.

Kunapuli P, Lee S, Zheng W, Alberts M, Kornienko O, Mull R, Kreamer A, Hwang JI, Simon MI, Strulovici B.

Anal Biochem. 2006 Apr 1;351(1):50-61. Epub 2006 Feb 3.

PMID:
16510108

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20.

Induction of the plasminogen activator inhibitor-2 in cells expressing the ZNF198/FGFR1 fusion kinase that is involved in atypical myeloproliferative disease.

Kasyapa CS, Kunapuli P, Hawthorn L, Cowell JK.

Blood. 2006 May 1;107(9):3693-9. Epub 2006 Jan 12.

PMID:
16410451
Free PMC Article

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21.

Mass spectroscopy identifies the splicing-associated proteins, PSF, hnRNP H3, hnRNP A2/B1, and TLS/FUS as interacting partners of the ZNF198 protein associated with rearrangement in myeloproliferative disease.

Kasyapa CS, Kunapuli P, Cowell JK.

Exp Cell Res. 2005 Sep 10;309(1):78-85.

PMID:
15975576

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22.

Application of division arrest technology to cell-based HTS: comparison with frozen and fresh cells.

Kunapuli P, Zheng W, Weber M, Solly K, Mull R, Platchek M, Cong M, Zhong Z, Strulovici B.

Assay Drug Dev Technol. 2005 Feb;3(1):17-26.

PMID:
15798392

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23.

Pharmacological characterization and radioligand binding properties of a high-affinity, nonpeptide, bradykinin B1 receptor antagonist.

Ransom RW, Harrell CM, Reiss DR, Murphy KL, Chang RS, Hess JF, Miller PJ, O'Malley SS, Hey PJ, Kunapuli P, Su DS, Markowitz MK, Wallace MA, Raab CE, Jones AN, Dean DC, Pettibone DJ, Freidinger RM, Bock MG.

Eur J Pharmacol. 2004 Sep 19;499(1-2):77-84.

PMID:
15363953

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24.

Miniaturization of whole live cell-based GPCR assays using microdispensing and detection systems.

Kornienko O, Lacson R, Kunapuli P, Schneeweis J, Hoffman I, Smith T, Alberts M, Inglese J, Strulovici B.

J Biomol Screen. 2004 Apr;9(3):186-95.

PMID:
15140380

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25.

A 1536-well cAMP assay for Gs- and Gi-coupled receptors using enzyme fragmentation complementation.

Weber M, Ferrer M, Zheng W, Inglese J, Strulovici B, Kunapuli P.

Assay Drug Dev Technol. 2004 Feb;2(1):39-49.

PMID:
15090209

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26.

LGI1, a putative tumor metastasis suppressor gene, controls in vitro invasiveness and expression of matrix metalloproteinases in glioma cells through the ERK1/2 pathway.

Kunapuli P, Kasyapa CS, Hawthorn L, Cowell JK.

J Biol Chem. 2004 May 28;279(22):23151-7. Epub 2004 Mar 26. Erratum in: J Biol Chem. 2007 Jan 26;282(4):2752.

PMID:
15047712
Free Article

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27.

Suppression of the cell proliferation and invasion phenotypes in glioma cells by the LGI1 gene.

Kunapuli P, Chitta KS, Cowell JK.

Oncogene. 2003 Jun 26;22(26):3985-91.

PMID:
12821932

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28.

ZNF198 protein, involved in rearrangement in myeloproliferative disease, forms complexes with the DNA repair-associated HHR6A/6B and RAD18 proteins.

Kunapuli P, Somerville R, Still IH, Cowell JK.

Oncogene. 2003 May 29;22(22):3417-23.

PMID:
12776193

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29.

Development of an intact cell reporter gene beta-lactamase assay for G protein-coupled receptors for high-throughput screening.

Kunapuli P, Ransom R, Murphy KL, Pettibone D, Kerby J, Grimwood S, Zuck P, Hodder P, Lacson R, Hoffman I, Inglese J, Strulovici B.

Anal Biochem. 2003 Mar 1;314(1):16-29.

PMID:
12633598

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30.

The oncogenic fusion protein-tyrosine kinase ZNF198/fibroblast growth factor receptor-1 has signaling function comparable with interleukin-6 cytokine receptors.

Baumann H, Kunapuli P, Tracy E, Cowell JK.

J Biol Chem. 2003 May 2;278(18):16198-208. Epub 2003 Feb 19.

PMID:
12594223
Free Article

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31.

Prostaglandin F2alpha (PGF2alpha) and the isoprostane, 8, 12-iso-isoprostane F2alpha-III, induce cardiomyocyte hypertrophy. Differential activation of downstream signaling pathways.

Kunapuli P, Lawson JA, Rokach JA, Meinkoth JL, FitzGerald GA.

J Biol Chem. 1998 Aug 28;273(35):22442-52.

PMID:
9712868
Free Article

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32.

Functional characterization of the ocular prostaglandin f2alpha (PGF2alpha) receptor. Activation by the isoprostane, 12-iso-PGF2alpha.

Kunapuli P, Lawson JA, Rokach J, FitzGerald GA.

J Biol Chem. 1997 Oct 24;272(43):27147-54.

PMID:
9341156
Free Article

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33.

Effect of different G protein-coupled receptor kinases on phosphorylation and desensitization of the alpha1B-adrenergic receptor.

Diviani D, Lattion AL, Larbi N, Kunapuli P, Pronin A, Benovic JL, Cotecchia S.

J Biol Chem. 1996 Mar 1;271(9):5049-58.

PMID:
8617782
Free Article

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34.

Agonist-dependent phosphorylation of human muscarinic receptors in Spodoptera frugiperda insect cell membranes by G protein-coupled receptor kinases.

Debburman SK, Kunapuli P, Benovic JL, Hosey MM.

Mol Pharmacol. 1995 Feb;47(2):224-33.

PMID:
7870029

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35.

Chromosomal mapping of the genes GPRK5 and GPRK6 encoding G protein-coupled receptor kinases GRK5 and GRK6.

Bullrich F, Druck T, Kunapuli P, Gomez J, Gripp KW, Schlegelberger B, Lasota J, Aronson M, Cannizzaro LA, Huebner K, et al.

Cytogenet Cell Genet. 1995;70(3-4):250-4.

PMID:
7789183

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36.

Phospholipid-stimulated autophosphorylation activates the G protein-coupled receptor kinase GRK5.

Kunapuli P, Gurevich VV, Benovic JL.

J Biol Chem. 1994 Apr 8;269(14):10209-12.

PMID:
8144599
Free Article

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37.

Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5.

Kunapuli P, Onorato JJ, Hosey MM, Benovic JL.

J Biol Chem. 1994 Jan 14;269(2):1099-105.

PMID:
8288567
Free Article

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38.

Cloning and expression of GRK5: a member of the G protein-coupled receptor kinase family.

Kunapuli P, Benovic JL.

Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5588-92.

PMID:
7685906
Free PMC Article

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