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High-mobility Group Box 1 Protein in Pediatric Trauma Patients With Acute Traumatic Coagulopathy or Disseminated Intravascular Coagulation.

Ulusoy E, Duman M, Çağlar A, Küme T, Er A, Akgül F, Çitlenbik H, Yilmaz D, Ören H.

J Pediatr Hematol Oncol. 2020 Mar 24. doi: 10.1097/MPH.0000000000001788. [Epub ahead of print]


Levels of Soluble Urokinase Plasminogen Activator Receptor in Pediatric Lower Respiratory Tract Infections.

Çitlenbik H, Ulusoy E, Er A, Çağlar A, Akgül F, Küme T, Yılmaz D, Duman M.

Pediatr Allergy Immunol Pulmonol. 2019 Sep 1;32(3):121-127. doi: 10.1089/ped.2018.0982. Epub 2019 Sep 17.


In Vivo Imaging of Schlemm's Canal and Limbal Vascular Network in Mouse Using Visible-Light OCT.

Zhang X, Beckmann L, Miller DA, Shao G, Cai Z, Sun C, Sheibani N, Liu X, Schuman J, Johnson M, Kume T, Zhang HF.

Invest Ophthalmol Vis Sci. 2020 Feb 7;61(2):23. doi: 10.1167/iovs.61.2.23.


Polypoid gallbladder neuroendocrine tumor diagnosed as benign polyp before surgery: A case report.

Naito S, Naito M, Yamamoto N, Kume T, Hosino S, Kinjyo Y, Naito Y, Naito H, Hasegawa S.

Mol Clin Oncol. 2020 Mar;12(3):225-229. doi: 10.3892/mco.2019.1971. Epub 2019 Dec 24.


Evaluation of Toxic Amyloid 42 Oligomers in Rat Primary Cerebral Cortex Cells and Human iPS-derived Neurons Treated with 10-Me-Aplog-1, a New PKC Activator.

Murakami K, Yoshimura M, Nakagawa S, Kume T, Kondo T, Inoue H, Irie K.

Int J Mol Sci. 2020 Feb 11;21(4). pii: E1179. doi: 10.3390/ijms21041179.


Clinical Impact of High-Sensitivity Cardiac Troponin T on the Chronic Phase of Stable Angina after a Successful Initial Percutaneous Coronary Intervention.

Okamoto H, Kume T, Koyama T, Tamada T, Yamada R, Neishi Y, Uemura S.

Acta Cardiol Sin. 2020 Jan;36(1):16-23. doi: 10.6515/ACS.202001_36(1).20190704C.


Protective Effect of 2',3'-Dihydroxy-4',6'-dimethoxychalcone on Glutamate-Induced Neurotoxicity in Primary Cortical Cultures.

Taguchi K, Izumi Y, Takada-Takatori Y, Akaike A, Kume T.

Biol Pharm Bull. 2020;43(1):184-187. doi: 10.1248/bpb.b19-00718.


Full-field microscope with twin Wolter mirrors for soft X-ray free-electron lasers.

Egawa S, Owada S, Motoyama H, Yamaguchi G, Matsuzawa Y, Kume T, Kubota Y, Tono K, Yabashi M, Ohashi H, Mimura H.

Opt Express. 2019 Nov 11;27(23):33889-33897. doi: 10.1364/OE.27.033889.


Limited stomatal regulation of the largest-size class of Dryobalanops aromatica in a Bornean tropical rainforest in response to artificial soil moisture reduction.

Yoshifuji N, Kumagai T, Ichie T, Kume T, Tateishi M, Inoue Y, Yoneyama A, Nakashizuka T.

J Plant Res. 2020 Mar;133(2):175-191. doi: 10.1007/s10265-019-01161-3. Epub 2019 Dec 19.


Is Ischemia-Modified Albumin a Reliable Marker in Accurate Diagnosis of Appendicitis in Children?

Ulusoy E, Çitlenbik H, Akgül F, Öztürk A, Şık N, Ulusoy O, Küme T, Yılmaz D, Duman M.

World J Surg. 2020 Apr;44(4):1309-1315. doi: 10.1007/s00268-019-05323-1.


Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis.

Welsh JD, Hoofnagle MH, Bamezai S, Oxendine M, Lim L, Hall JD, Yang J, Schultz S, Engel JD, Kume T, Oliver G, Jimenez JM, Kahn ML.

J Clin Invest. 2019 Dec 2;129(12):5489-5500. doi: 10.1172/JCI124791.


α-Synuclein oligomers mediate the aberrant form of spike-induced calcium release from IP3 receptor.

Yamamoto K, Izumi Y, Arifuku M, Kume T, Sawada H.

Sci Rep. 2019 Nov 4;9(1):15977. doi: 10.1038/s41598-019-52135-3.


Prevalence and Clinical Significance of Layered Plaque in Patients With Stable Angina Pectoris - Evaluation With Histopathology and Optical Coherence Tomography.

Okamoto H, Kume T, Yamada R, Koyama T, Tamada T, Imai K, Neishi Y, Uemura S.

Circ J. 2019 Nov 25;83(12):2452-2459. doi: 10.1253/circj.CJ-19-0640. Epub 2019 Oct 22.


Organ/Tissue-Specific Vascular Endothelial Cell Heterogeneity in Health and Disease.

Minami T, Muramatsu M, Kume T.

Biol Pharm Bull. 2019;42(10):1609-1619. doi: 10.1248/bpb.b19-00531. Review.


Increased CCL6 expression in astrocytes and neuronal protection from neuron-astrocyte interactions.

Nakagawa S, Izumi Y, Takada-Takatori Y, Akaike A, Kume T.

Biochem Biophys Res Commun. 2019 Nov 19;519(4):777-782. doi: 10.1016/j.bbrc.2019.09.030. Epub 2019 Sep 21.


Effects of 2'-3'-dihydroxy-4',6'-dimethoxychalcone derived from green perilla on auricle thickness in chronic contact dermatitis model mice.

Takada-Takatori Y, Takeda Y, Imai R, Izumi Y, Akaike A, Tsuchida K, Kume T.

J Pharmacol Sci. 2019 Sep;141(1):17-24. doi: 10.1016/j.jphs.2019.08.004. Epub 2019 Aug 28.


Benefit of Reducing Body Weight Loss with A Nutritional Support Pathway in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation.

Aoyama T, Yoshitsugu K, Fukaya M, Kume T, Kawashima M, Nakajima K, Arai H, Imataki O, Enami T, Tatara R, Ikeda T.

Med Sci Monit Basic Res. 2019 Sep 10;25:187-198. doi: 10.12659/MSMBR.917329.


Intense sub-micrometre focusing of soft X-ray free-electron laser beyond 1016 W cm-2 with an ellipsoidal mirror.

Motoyama H, Owada S, Yamaguchi G, Kume T, Egawa S, Tono K, Inubushi Y, Koyama T, Yabashi M, Ohashi H, Mimura H.

J Synchrotron Radiat. 2019 Sep 1;26(Pt 5):1406-1411. doi: 10.1107/S1600577519007057. Epub 2019 Aug 5.


Protective Effects of 2',3'-Dihydroxy-4',6'-dimethoxychalcone Derived from Green Perilla Leaves against UV Radiation-Induced Cell Injury in Human Cultured Keratinocytes.

Takada-Takatori Y, Tomii Y, Takemasa S, Takeda Y, Izumi Y, Akaike A, Tsuchida K, Kume T.

Biol Pharm Bull. 2019 Nov 1;42(11):1936-1941. doi: 10.1248/bpb.b19-00618. Epub 2019 Aug 27.


Protective Effect of Green Perilla-Derived Chalcone Derivative DDC on Amyloid β Protein-Induced Neurotoxicity in Primary Cortical Neurons.

Iwasaki M, Izuo N, Izumi Y, Takada-Takatori Y, Akaike A, Kume T.

Biol Pharm Bull. 2019 Nov 1;42(11):1942-1946. doi: 10.1248/bpb.b19-00657. Epub 2019 Aug 29.


Donepezil modulates amyloid precursor protein endocytosis and reduction by up-regulation of SNX33 expression in primary cortical neurons.

Takada-Takatori Y, Nakagawa S, Kimata R, Nao Y, Mizukawa Y, Urushidani T, Izumi Y, Akaike A, Tsuchida K, Kume T.

Sci Rep. 2019 Aug 15;9(1):11922. doi: 10.1038/s41598-019-47462-4.


Nicotinic Acetylcholine Receptor Signaling: Roles in Neuroprotection.

Kume T, Takada-Takatori Y.

In: Akaike A, Shimohama S, Misu Y, editors. Nicotinic Acetylcholine Receptor Signaling in Neuroprotection [Internet]. Singapore: Springer; 2018. Chapter 4.
2018 Apr 4.


Retrograde coronary intervention for chronic total occlusion of RCA ostium with anomalous origin: A case report.

Yamada R, Hirohata A, Kume T, Neishi Y, Uemura S.

J Cardiol Cases. 2019 Feb 21;19(6):182-185. doi: 10.1016/j.jccase.2019.01.003. eCollection 2019 Jun.


Estimation of changes in serum creatinine and creatinine clearance caused by renal transporter inhibition in healthy subjects.

Nakada T, Kudo T, Kume T, Kusuhara H, Ito K.

Drug Metab Pharmacokinet. 2019 Aug;34(4):233-238. doi: 10.1016/j.dmpk.2019.02.006. Epub 2019 Mar 2.


Effect of Left Ventricular Reverse Remodeling on Long-term Outcomes After Aortic Valve Replacement.

Izumi C, Kitai T, Kume T, Onishi T, Yuda S, Hirata K, Yamashita E, Kawata T, Nishimura K, Takeuchi M, Nakatani S.

Am J Cardiol. 2019 Jul 1;124(1):105-112. doi: 10.1016/j.amjcard.2019.04.010. Epub 2019 Apr 9.


Vertical variation in wood CO2 efflux is not uniformly related to height: measurement across various species and sizes of Bornean tropical rainforest trees.

Katayama A, Kume T, Ichihashi R, Nakagawa M.

Tree Physiol. 2019 Jun 1;39(6):1000-1008. doi: 10.1093/treephys/tpz022.


The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells.

Adane B, Ye H, Khan N, Pei S, Minhajuddin M, Stevens BM, Jones CL, D'Alessandro A, Reisz JA, Zaberezhnyy V, Gasparetto M, Ho TC, Kelly KK, Myers JR, Ashton JM, Siegenthaler J, Kume T, Campbell EL, Pollyea DA, Becker MW, Jordan CT.

Cell Rep. 2019 Apr 2;27(1):238-254.e6. doi: 10.1016/j.celrep.2019.03.009.


Animal models of chronic pain increase spontaneous glutamatergic transmission in adult rat spinal dorsal horn in vitro and in vivo.

Uta D, Kato G, Doi A, Andoh T, Kume T, Yoshimura M, Koga K.

Biochem Biophys Res Commun. 2019 Apr 30;512(2):352-359. doi: 10.1016/j.bbrc.2019.03.051. Epub 2019 Mar 17.


[Current situation and problems of pharmacology education in the Faculty of Pharmaceutical Sciences].

Kume T.

Nihon Yakurigaku Zasshi. 2019;153(3):107-110. doi: 10.1254/fpj.153.107. Japanese.


Development of electroforming process for soft x-ray ellipsoidal mirror.

Kume T, Takei Y, Egawa S, Motoyama H, Takeo Y, Yamaguchi G, Mimura H.

Rev Sci Instrum. 2019 Feb;90(2):021718. doi: 10.1063/1.5057432.


Functional characterization for polymorphic organic anion transporting polypeptides (OATP/SLCO1B1, 1B3, 2B1) of monkeys recombinantly expressed with various OATP probes.

Takahashi T, Uno Y, Yamazaki H, Kume T.

Biopharm Drug Dispos. 2019 Feb;40(2):62-69. doi: 10.1002/bdd.2171. Epub 2019 Feb 10.


Cardiac function response to stenting in atherosclerotic renal artery disease with and without heart failure: results from the Carmel study.

Kawarada O, Kume T, Zen K, Nakamura S, Hozawa K, Akimitsu T, Asano H, Ando H, Yamamoto Y, Yamashita T, Shinozaki N, Odashiro K, Sato T, Yuba K, Sakanoue Y, Uzu T, Okada K, Fitzgerald PJ, Honda Y, Yasuda S.

ESC Heart Fail. 2019 Apr;6(2):319-327. doi: 10.1002/ehf2.12391. Epub 2019 Jan 7.


Effect of Blood Cell Subtypes Lysis on Routine Biochemical Tests.

Ünlü B, Küme T, Emek M, Örmen M, Doğan Y, Şişman AR, Ergör G, Çoker C.

J Med Biochem. 2018 Jan 1;37(1):67-77. doi: 10.1515/jomb-2017-0044. eCollection 2018 Jan.


Meta-analysis of the likelihood of FOXC1 expression in early- and late-stage tumors.

Kume T, Shackour T.

Oncotarget. 2018 Nov 27;9(93):36625-36630. doi: 10.18632/oncotarget.26358. eCollection 2018 Nov 27.


The relationship between urotensin II and insulin resistance in women with gestational diabetes mellitus.

Calan M, Arkan T, Kume T, Bayraktar F.

Hormones (Athens). 2019 Mar;18(1):91-97. doi: 10.1007/s42000-018-0084-7. Epub 2018 Nov 23.


Image analysis procedure for the optical scanning of fine-root dynamics: errors depending on the observer and root-viewing window size.

Kume T, Ohashi M, Makita N, Kho LK, Katayama A, Endo I, Matsumoto K, Ikeno H.

Tree Physiol. 2018 Dec 1;38(12):1927-1938. doi: 10.1093/treephys/tpy124.


Foxc2 is required for proper cardiac neural crest cell migration, outflow tract septation, and ventricle expansion.

Inman KE, Caiaffa CD, Melton KR, Sandell LL, Achilleos A, Kume T, Trainor PA.

Dev Dyn. 2018 Dec;247(12):1286-1296. doi: 10.1002/dvdy.24684.


Role of fecal calprotectin in the assessment of intestinal inflammation in children with familial Mediterranean fever.

Gucenmez OA, Kume T, Makay B, Babayigit O, Arslan N, Unsal E.

Int J Rheum Dis. 2018 Oct;21(10):1844-1848. doi: 10.1111/1756-185X.13396. Epub 2018 Oct 21.


Meta-analysis of the likelihood of FOXC2 expression in early- and late-stage tumors.

Kume T, Shackour T.

Oncotarget. 2018 Sep 7;9(70):33396-33402. doi: 10.18632/oncotarget.26087. eCollection 2018 Sep 7.


Fabrication of a precise ellipsoidal mirror for soft X-ray nanofocusing.

Mimura H, Takei Y, Kume T, Takeo Y, Motoyama H, Egawa S, Matsuzawa Y, Yamaguchi G, Senba Y, Kishimoto H, Ohashi H.

Rev Sci Instrum. 2018 Sep;89(9):093104. doi: 10.1063/1.5035323.


Corrigendum to "Different Effects of Myoinositol plus Folic Acid versus Combined Oral Treatment on Androgen Levels in PCOS Women".

Ozay AC, Ozay OE, Okyay RE, Cagliyan E, Kume T, Gulekli B.

Int J Endocrinol. 2018 Sep 10;2018:7502102. doi: 10.1155/2018/7502102. eCollection 2018.


Coronary bifurcation bench test using multimodality imaging: Impact of stent strut link location on stent deformity and jailed side-branch orifices during re-proximal optimizing technique.

Kume T, Yamada R, Koyama T, Tamada T, Imai K, Fukuhara K, Goryo Y, Kawamura A, Okamoto H, Neishi Y, Uemura S.

Catheter Cardiovasc Interv. 2019 Jan 1;93(1):E17-E23. doi: 10.1002/ccd.27719. Epub 2018 Sep 23.


Inhibitory effect of the gut microbial linoleic acid metabolites, 10-oxo-trans-11-octadecenoic acid and 10-hydroxy-cis-12-octadecenoic acid, on BV-2 microglial cell activation.

Ikeguchi S, Izumi Y, Kitamura N, Kishino S, Ogawa J, Akaike A, Kume T.

J Pharmacol Sci. 2018 Sep;138(1):9-15. doi: 10.1016/j.jphs.2018.06.015. Epub 2018 Sep 5.


Assessment of the results of a three-year program for National Standardization and Quality Improvement of Medical Laboratories on Drug of Abuse Testing by the Ministry of Health in Turkey.

Küme T, Mercan F, Topsakal H, Karakukcu C, Şeneş M, Pınar A, Gürler M, Kalafat H, Ünal B, Verstraete AG, Hamurtekin Y, Aydınlı A, Şenol Y, Eğin ME, Cihan A, Kazancı EG, Gümüş E.

Drug Test Anal. 2019 Feb;11(2):215-222. doi: 10.1002/dta.2479. Epub 2018 Sep 17.


Comparison of levetiracetam with phenytoin for the prevention of intravenous busulfan-induced seizures in hematopoietic cell transplantation recipients.

Akiyama K, Kume T, Fukaya M, Shiki I, Enami T, Tatara R, Shino M, Ikeda T.

Cancer Chemother Pharmacol. 2018 Oct;82(4):717-721. doi: 10.1007/s00280-018-3659-8. Epub 2018 Aug 6.


A Randomized Study of Distal Filter Protection Versus Conventional Treatment During Percutaneous Coronary Intervention in Patients With Attenuated Plaque Identified by Intravascular Ultrasound.

Hibi K, Kozuma K, Sonoda S, Endo T, Tanaka H, Kyono H, Koshida R, Ishihara T, Awata M, Kume T, Tanabe K, Morino Y, Tsukahara K, Ikari Y, Fujii K, Yamasaki M, Yamanaka T, Kimura K, Isshiki T; VAMPIRE 3 Investigators.

JACC Cardiovasc Interv. 2018 Aug 27;11(16):1545-1555. doi: 10.1016/j.jcin.2018.03.021. Epub 2018 Aug 1.


Positive correlation of galanin with insulin resistance and triglyceride levels in obese children

Acar S, Paketçi A, Küme T, Demir K, Gürsoy Çalan Ö, Böber E, Abacı A.

Turk J Med Sci. 2018 Jun 14;48(3):560-568. doi: 10.3906/sag-1710-68.


A case of ventricular septal defect detected after myomectomy by intra-operative transesophageal echocardiography in patient with situs inversus and double-chambered right ventricle.

Kawamura A, Imai K, Kume T, Tanemoto K, Tamada T, Okamoto H, Uemura S.

J Echocardiogr. 2018 Dec;16(4):178-179. doi: 10.1007/s12574-018-0376-6. Epub 2018 May 8. No abstract available.


Increased concentrations of serum nesfatin-1 levels in childhood with idiopathic chronic malnutrition

Acar S, Çatlı G, Küme T, Tuhan H, Gürsoy Çalan Ö, Demir K, Böber E, Abacı A.

Turk J Med Sci. 2018 Apr 30;48(2):378-385. doi: 10.3906/sag-1705-20.


Vascular Healing Response after Everolimus-Eluting Stent Implantation in Acute Coronary Syndrome Culprit Lesions: Comparison with Implantation in Stable Angina Pectoris.

Goryo Y, Kume T, Ueda T, Watanabe M, Yamada R, Neishi Y, Saito Y, Uemura S.

Acta Cardiol Sin. 2018 Mar;34(2):124-129. doi: 10.6515/ACS.201803_34(2).20171115A.

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