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Items: 1 to 50 of 483

1.

On-Surface Modification of Copper Cathodes by Copper(I)-Catalyzed Azide Alkyne Cycloaddition and CO2 Reduction in Organic Environments.

Igarashi R, Takeuchi R, Kubo K, Mizuta T, Kume S.

Front Chem. 2019 Dec 17;7:860. doi: 10.3389/fchem.2019.00860. eCollection 2019.

2.

Monkeys mutant for PKD1 recapitulate human autosomal dominant polycystic kidney disease.

Tsukiyama T, Kobayashi K, Nakaya M, Iwatani C, Seita Y, Tsuchiya H, Matsushita J, Kitajima K, Kawamoto I, Nakagawa T, Fukuda K, Iwakiri T, Izumi H, Itagaki I, Kume S, Maegawa H, Nishinakamura R, Nishio S, Nakamura S, Kawauchi A, Ema M.

Nat Commun. 2019 Dec 11;10(1):5517. doi: 10.1038/s41467-019-13398-6.

3.

Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina.

Notomi S, Ishihara K, Efstathiou NE, Lee JJ, Hisatomi T, Tachibana T, Konstantinou EK, Ueta T, Murakami Y, Maidana DE, Ikeda Y, Kume S, Terasaki H, Sonoda S, Blanz J, Young L, Sakamoto T, Sonoda KH, Saftig P, Ishibashi T, Miller JW, Kroemer G, Vavvas DG.

Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23724-23734. doi: 10.1073/pnas.1906643116. Epub 2019 Nov 7.

4.

Protonation and electrochemical properties of a bisphosphide diiron hexacarbonyl complex bearing amino groups on the phosphide bridge.

Shimamura T, Maeno Y, Kubo K, Kume S, Greco C, Mizuta T.

Dalton Trans. 2019 Nov 12;48(44):16595-16603. doi: 10.1039/c9dt03427g.

PMID:
31651000
5.

Pathophysiological roles of nutrient-sensing mechanisms in diabetes and its complications.

Kume S.

Diabetol Int. 2019 Aug 13;10(4):245-249. doi: 10.1007/s13340-019-00406-9. eCollection 2019 Oct.

PMID:
31592045
6.

Detailed analysis at a single-cell level of cells undergoing pancreatic differentiation.

Shiraki N, Kume S.

J Diabetes Investig. 2020 Jan;11(1):20-21. doi: 10.1111/jdi.13140. Epub 2019 Sep 25.

7.

[Basaloid Squamous Cell Carcinoma;Report of a Case].

Ito K, Haga N, Kasai Y, Masuya D, Takata N, Tanaka Y, Miyoshi K, Kume S, Inoue S, Monden K, Okada N, Ootsuka K, Suzuki Y.

Kyobu Geka. 2019 Aug;72(8):641-643. Japanese.

PMID:
31353361
8.

Collagen vitrigel promotes hepatocytic differentiation of induced pluripotent stem cells into functional hepatocyte-like cells.

Nakai S, Shibata I, Shitamichi T, Yamaguchi H, Takagi N, Inoue T, Nakagawa T, Kiyokawa J, Wakabayashi S, Miyoshi T, Higashi E, Ishida S, Shiraki N, Kume S.

Biol Open. 2019 Jul 2;8(7). pii: bio042192. doi: 10.1242/bio.042192.

9.

A culture substratum with net-like polyamide fibers promotes the differentiation of mouse and human pluripotent stem cells to insulin-producing cells.

Kaitsuka T, Kojima R, Kawabe M, Noguchi H, Shiraki N, Kume S, Tomizawa K.

Biomed Mater. 2019 Jun 19;14(4):045019. doi: 10.1088/1748-605X/ab261c.

PMID:
31151115
10.

Protein O-GlcNAcylation Is Essential for the Maintenance of Renal Energy Homeostasis and Function via Lipolysis during Fasting and Diabetes.

Sugahara S, Kume S, Chin-Kanasaki M, Tomita I, Yasuda-Yamahara M, Yamahara K, Takeda N, Osawa N, Yanagita M, Araki SI, Maegawa H.

J Am Soc Nephrol. 2019 Jun;30(6):962-978. doi: 10.1681/ASN.2018090950. Epub 2019 May 1.

PMID:
31043434
11.

[A Case of Nephrotic Syndrome Due to SOX plus Bmab Therapy for Liver Metastasis of Rectal Cancer].

Murase H, Iseki H, Ogawa A, Kamachi K, Mitsuoka A, Hayashi M, Seongjin P, Fukuuchi A, Kume S, Uriuda Y, Hirayama K, Negishi K.

Gan To Kagaku Ryoho. 2019 Feb;46(2):288-290. Japanese.

PMID:
30914536
12.

Asparagine-linked glycosylation modifies voltage-dependent gating properties of CaV3.1-T-type Ca2+ channel.

Liu Y, Wang P, Ma F, Zheng M, Liu G, Kume S, Kurokawa T, Ono K.

J Physiol Sci. 2019 Mar;69(2):335-343. doi: 10.1007/s12576-018-0650-4. Epub 2019 Jan 1.

PMID:
30600443
13.

A role for bone marrow-derived cells in diabetic nephropathy.

Nobuta H, Katagi M, Kume S, Terashima T, Araki SI, Maegawa H, Kojima H, Nakagawa T.

FASEB J. 2019 Mar;33(3):4067-4076. doi: 10.1096/fj.201801825R. Epub 2018 Nov 29.

PMID:
30496699
14.

Secular changes in clinical manifestations of kidney disease among Japanese adults with type 2 diabetes from 1996 to 2014.

Kume S, Araki SI, Ugi S, Morino K, Koya D, Nishio Y, Haneda M, Kashiwagi A, Maegawa H.

J Diabetes Investig. 2019 Jul;10(4):1032-1040. doi: 10.1111/jdi.12977. Epub 2019 Jan 1.

15.

Spontaneously Diabetic Torii (SDT) Fatty Rat, a Novel Animal Model of Type 2 Diabetes Mellitus, Shows Blunted Circadian Rhythms and Melatonin Secretion.

Sakimura K, Maekawa T, Kume SI, Ohta T.

Int J Endocrinol. 2018 Sep 23;2018:9065690. doi: 10.1155/2018/9065690. eCollection 2018.

16.

Induced Pluripotent Stem Cell Elimination in a Cell Sheet by Methionine-Free and 42°C Condition for Tumor Prevention.

Matsuura K, Ito K, Shiraki N, Kume S, Hagiwara N, Shimizu T.

Tissue Eng Part C Methods. 2018 Oct;24(10):605-615. doi: 10.1089/ten.TEC.2018.0228.

PMID:
30234460
17.

Future Perspectives for the Treatment of Diabetes: Importance of a Regulatory Framework.

Tsukamoto K, Cnop M, Mori D, Kume S, Anazawa T, Doi M, Chikazawa K, Matsumaru N.

Ther Innov Regul Sci. 2019 Jul;53(4):535-541. doi: 10.1177/2168479018795854. Epub 2018 Sep 3.

PMID:
30176740
18.

Two mutations at different positions in the CNBH domain of the hERG channel accelerate deactivation and impair the interaction with the EAG domain.

Kume S, Shimomura T, Tateyama M, Kubo Y.

J Physiol. 2018 Oct;596(19):4629-4650. doi: 10.1113/JP276208. Epub 2018 Sep 3.

19.

Different murine-derived feeder cells alter the definitive endoderm differentiation of human induced pluripotent stem cells.

Shoji M, Minato H, Ogaki S, Seki M, Suzuki Y, Kume S, Kuzuhara T.

PLoS One. 2018 Jul 26;13(7):e0201239. doi: 10.1371/journal.pone.0201239. eCollection 2018.

20.

[Fetal Adenocarcinoma of the Lung].

Ito K, Kasai Y, Masuya D, Takata N, Tanaka Y, Kume S, Inoue S, Monden K, Okada N, Yoshimatsu H, Suzuki Y.

Kyobu Geka. 2018 Jun;71(6):438-441. Japanese.

PMID:
30042244
21.

Pathophysiological abnormalities in the brains of Spontaneously Diabetic Torii-Lepr fa (SDT fatty) rats, a novel type 2 diabetic model.

Maekawa T, Ohta T, Kume S.

J Vet Med Sci. 2018 Sep 13;80(9):1385-1391. doi: 10.1292/jvms.18-0296. Epub 2018 Jul 17.

22.

Role of dietary amino acid balance in diet restriction-mediated lifespan extension, renoprotection, and muscle weakness in aged mice.

Yoshida S, Yamahara K, Kume S, Koya D, Yasuda-Yamahara M, Takeda N, Osawa N, Chin-Kanasaki M, Adachi Y, Nagao K, Maegawa H, Araki SI.

Aging Cell. 2018 Aug;17(4):e12796. doi: 10.1111/acel.12796. Epub 2018 Jun 25.

23.

Neointimal formation after carotid artery stenting: phantom and clinical evaluation of model-based iterative reconstruction (MBIR).

Yokomachi K, Tatsugami F, Higaki T, Kume S, Sakamoto S, Okazaki T, Kurisu K, Nakamura Y, Baba Y, Iida M, Awai K.

Eur Radiol. 2019 Jan;29(1):161-167. doi: 10.1007/s00330-018-5598-5. Epub 2018 Jun 22.

PMID:
29934669
24.

Effects of supplemental β-carotene on colostral immunoglobulin and plasma β-carotene and immunoglobulin in Japanese Black cows.

Ishida M, Nishijima Y, Ikeda S, Yoshitani K, Obata A, Sugie Y, Aoki Y, Yamaji T, Fujita M, Nakatsuji Y, Kume S.

Anim Sci J. 2018 Aug;89(8):1102-1106. doi: 10.1111/asj.13032. Epub 2018 May 29.

PMID:
29808628
25.

Depression-related behavioural and neuroendocrine changes in the Spontaneously Diabetic Torii (SDT) fatty rat, an animal model of type 2 diabetes mellitus.

Sakimura K, Maekawa T, Sasagawa K, Ishii Y, Kume SI, Ohta T.

Clin Exp Pharmacol Physiol. 2018 May 14. doi: 10.1111/1440-1681.12965. [Epub ahead of print]

PMID:
29757463
26.

[Growth Process of Cystic Lung Cancer Followed with Computed Tomography Findings Over 5 Years].

Kasai Y, Ito K, Masuya D, Kume S, Inoue S, Suzuki Y.

Kyobu Geka. 2018 May;71(5):336-338. Japanese.

PMID:
29755083
27.

Pathophysiological characteristics of non-alcoholic steatohepatitis-like changes in cholesterol-loaded type 2 diabetic rats.

Toriniwa Y, Muramatsu M, Ishii Y, Riya E, Miyajima K, Ohshida S, Kitatani K, Takekoshi S, Matsui T, Kume S, Yamada T, Ohta T.

Physiol Res. 2018 Aug 16;67(4):601-612. Epub 2018 May 10.

28.

Investigation of pharmacological responses to anti-diabetic drugs in female Spontaneously Diabetic Torii (SDT) fatty rats, a new nonalcoholic steatohepatitis (NASH) model.

Toriniwa Y, Saito T, Miyajima K, Ishii Y, Uno K, Maekawa T, Matsui T, Kume S, Yamada T, Ohta T.

J Vet Med Sci. 2018 Jun 6;80(6):878-885. doi: 10.1292/jvms.18-0119. Epub 2018 Apr 10.

29.

Upregulation of Mitf by Phenolic Compounds-Rich Cymbopogon schoenanthus Treatment Promotes Melanogenesis in B16 Melanoma Cells and Human Epidermal Melanocytes.

Villareal MO, Kume S, Neffati M, Isoda H.

Biomed Res Int. 2017;2017:8303671. doi: 10.1155/2017/8303671. Epub 2017 Nov 21.

30.

Lipofection of siRNA into bovine 8-16-cell stage embryos using zona removal and the well-of-the-well culture system.

Ikeda S, Sugimoto M, Kume S.

J Reprod Dev. 2018 Apr 13;64(2):199-202. doi: 10.1262/jrd.2017-137. Epub 2018 Jan 21.

31.

Lack of O-GlcNAcylation enhances exercise-dependent glucose utilization potentially through AMP-activated protein kinase activation in skeletal muscle.

Murata K, Morino K, Ida S, Ohashi N, Lemecha M, Park SY, Ishikado A, Kume S, Choi CS, Sekine O, Ugi S, Maegawa H.

Biochem Biophys Res Commun. 2018 Jan 8;495(2):2098-2104. doi: 10.1016/j.bbrc.2017.12.081. Epub 2017 Dec 15.

PMID:
29253568
32.

Novel chloride-centered Ag18 clusters featuring a cuboctahedral Ag12 skeleton.

Shen H, Kubo K, Kume S, Zhang L, Mizuta T.

Dalton Trans. 2017 Nov 28;46(46):16199-16204. doi: 10.1039/c7dt03195e.

PMID:
29182692
33.

Overexpression of acetyl CoA carboxylase β exacerbates podocyte injury in the kidney of streptozotocin-induced diabetic mice.

Tanaka Y, Kume S, Maeda S, Osawa N, Takeda N, Chin-Kanasaki M, Isshiki K, Ugi S, Oshima I, Uzu T, Maegawa H, Araki SI.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):1115-1121. doi: 10.1016/j.bbrc.2017.11.145. Epub 2017 Nov 23.

PMID:
29175208
34.

Enzymatically synthesized megalo-type isomaltosaccharides enhance the barrier function of the tight junction in the intestinal epithelium.

Hara H, Kume S, Iizuka T, Fujimoto Y, Kimura A.

Biosci Biotechnol Biochem. 2018 Apr;82(4):629-635. doi: 10.1080/09168451.2017.1398065. Epub 2017 Nov 27.

35.

Sweetness induces sleep through gustatory signalling independent of nutritional value in a starved fruit fly.

Hasegawa T, Tomita J, Hashimoto R, Ueno T, Kume S, Kume K.

Sci Rep. 2017 Oct 30;7(1):14355. doi: 10.1038/s41598-017-14608-1.

36.

Impact of obesity on annual medical expenditures and diabetes care in Japanese patients with type 2 diabetes mellitus.

Kusunoki-Tsuji C, Araki SI, Kume S, Chin-Kanasaki M, Osawa N, Morino K, Sekine O, Ugi S, Kashiwagi A, Maegawa H.

J Diabetes Investig. 2018 Jul;9(4):776-781. doi: 10.1111/jdi.12766. Epub 2017 Nov 22. Erratum in: J Diabetes Investig. 2019 Mar;10(2):554.

37.

Inhibition of Cdk5 Promotes β-Cell Differentiation From Ductal Progenitors.

Liu KC, Leuckx G, Sakano D, Seymour PA, Mattsson CL, Rautio L, Staels W, Verdonck Y, Serup P, Kume S, Heimberg H, Andersson O.

Diabetes. 2018 Jan;67(1):58-70. doi: 10.2337/db16-1587. Epub 2017 Oct 6.

38.

Pathophysiological profiles of SDT fatty rats, a potential new diabetic peripheral neuropathy model.

Maekawa T, Tadaki H, Sasase T, Motohashi Y, Miyajima K, Ohta T, Kume S.

J Pharmacol Toxicol Methods. 2017 Nov - Dec;88(Pt 2):160-166. doi: 10.1016/j.vascn.2017.09.257. Epub 2017 Sep 29.

PMID:
28970182
39.

Comprehensive Evaluation of the Binding of Lipocalin-Type Prostaglandin D Synthase to Poorly Water-Soluble Drugs.

Teraoka Y, Kume S, Lin Y, Atsuji S, Inui T.

Mol Pharm. 2017 Oct 2;14(10):3558-3567. doi: 10.1021/acs.molpharmaceut.7b00590. Epub 2017 Sep 8.

PMID:
28829147
40.

Capillary-Inserted Rotor Design for HRµMASNMR-Based Metabolomics on Mass-Limited Neurospheres.

Duong NT, Yamato M, Nakano M, Kume S, Tamura Y, Kataoka Y, Wong A, Nishiyama Y.

Molecules. 2017 Aug 3;22(8). pii: E1289. doi: 10.3390/molecules22081289.

41.

The RPMI-1640 vitamin mixture promotes bovine blastocyst development in vitro and downregulates gene expression of TXNIP with epigenetic modification of associated histones.

Ikeda S, Sugimoto M, Kume S.

J Dev Orig Health Dis. 2018 Feb;9(1):87-94. doi: 10.1017/S2040174417000563. Epub 2017 Aug 2.

PMID:
28764817
42.

Genetic analysis of the regulation of the voltage-gated calcium channel homolog Cch1 by the γ subunit homolog Ecm7 and cortical ER protein Scs2 in yeast.

Kato T, Kubo A, Nagayama T, Kume S, Tanaka C, Nakayama Y, Iida K, Iida H.

PLoS One. 2017 Jul 24;12(7):e0181436. doi: 10.1371/journal.pone.0181436. eCollection 2017.

43.

Diverse metabolic effects of O-GlcNAcylation in the pancreas but limited effects in insulin-sensitive organs in mice.

Ida S, Morino K, Sekine O, Ohashi N, Kume S, Chano T, Iwasaki K, Harada N, Inagaki N, Ugi S, Maegawa H.

Diabetologia. 2017 Sep;60(9):1761-1769. doi: 10.1007/s00125-017-4327-y. Epub 2017 Jun 22.

PMID:
28642969
44.

Pivotal Role of O-GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis.

Ohashi N, Morino K, Ida S, Sekine O, Lemecha M, Kume S, Park SY, Choi CS, Ugi S, Maegawa H.

Diabetes. 2017 Sep;66(9):2351-2362. doi: 10.2337/db16-1427. Epub 2017 Jun 21.

45.

Role of methionine adenosyltransferase 2A in bovine preimplantation development and its associated genomic regions.

Ikeda S, Kawahara-Miki R, Iwata H, Sugimoto M, Kume S.

Sci Rep. 2017 Jun 19;7(1):3800. doi: 10.1038/s41598-017-04003-1.

46.

Music Improves Subjective Feelings Leading to Cardiac Autonomic Nervous Modulation: A Pilot Study.

Kume S, Nishimura Y, Mizuno K, Sakimoto N, Hori H, Tamura Y, Yamato M, Mitsuhashi R, Akiba K, Koizumi JI, Watanabe Y, Kataoka Y.

Front Neurosci. 2017 Mar 10;11:108. doi: 10.3389/fnins.2017.00108. eCollection 2017.

47.

O-linked β-N-acetylglucosamine modification of proteins is essential for foot process maturation and survival in podocytes.

Ono S, Kume S, Yasuda-Yamahara M, Yamahara K, Takeda N, Chin-Kanasaki M, Araki H, Sekine O, Yokoi H, Mukoyama M, Uzu T, Araki SI, Maegawa H.

Nephrol Dial Transplant. 2017 Sep 1;32(9):1477-1487. doi: 10.1093/ndt/gfw463.

PMID:
28339907
48.

Erythropoietin facilitates definitive endodermal differentiation of mouse embryonic stem cells via activation of ERK signaling.

Kaitsuka T, Kobayashi K, Otsuka W, Kubo T, Hakim F, Wei FY, Shiraki N, Kume S, Tomizawa K.

Am J Physiol Cell Physiol. 2017 May 1;312(5):C573-C582. doi: 10.1152/ajpcell.00071.2016. Epub 2017 Mar 15.

49.

Mild electrical stimulation with heat shock guides differentiation of embryonic stem cells into Pdx1-expressing cells within the definitive endoderm.

Koga T, Shiraki N, Yano S, Suico MA, Morino-Koga S, Sato T, Shuto T, Kume S, Kai H.

BMC Biotechnol. 2017 Feb 15;17(1):14. doi: 10.1186/s12896-017-0331-z.

50.

NG2 glial cells regulate neuroimmunological responses to maintain neuronal function and survival.

Nakano M, Tamura Y, Yamato M, Kume S, Eguchi A, Takata K, Watanabe Y, Kataoka Y.

Sci Rep. 2017 Feb 14;7:42041. doi: 10.1038/srep42041.

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