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Items: 1 to 50 of 263

1.

Cefixime-associated acute generalized exanthematous pustulosis: Rare cases in India.

Kumar V, Kalaiselvan V, Kumar AP, Saurabh A, Thota P, Sidhu S, Medhi B.

Indian J Pharmacol. 2018 Jul-Aug;50(4):204-207. doi: 10.4103/ijp.IJP_673_17.

PMID:
30505057
2.

N-Substituted Pyrido-1,4-Oxazin-3-Ones Induce Apoptosis of Hepatocellular Carcinoma Cells by Targeting NF-κB Signaling Pathway.

Mohan CD, Bharathkumar H, Dukanya, Rangappa S, Shanmugam MK, Chinnathambi A, Alharbi SA, Alahmadi TA, Bhattacharjee A, Lobie PE, Deivasigamani A, Hui KM, Sethi G, Basappa, Rangappa KS, Kumar AP.

Front Pharmacol. 2018 Nov 5;9:1125. doi: 10.3389/fphar.2018.01125. eCollection 2018.

3.
4.

A Review on Liquid Chromatography-Tandem Mass Spectrometry Methods for Rapid Quantification of Oncology Drugs.

Wong AL, Xiang X, Ong PS, Mitchell EQY, Syn N, Wee I, Kumar AP, Yong WP, Sethi G, Goh BC, Ho PC, Wang L.

Pharmaceutics. 2018 Nov 8;10(4). pii: E221. doi: 10.3390/pharmaceutics10040221. Review.

5.

TIPE Family of Proteins and Its Implications in Different Chronic Diseases.

Bordoloi D, Banik K, Shabnam B, Padmavathi G, Monisha J, Arfuso F, Dharmarajan A, Mao X, Lim LHK, Wang L, Fan L, Hui KM, Kumar AP, Sethi G, Kunnumakkara AB.

Int J Mol Sci. 2018 Sep 29;19(10). pii: E2974. doi: 10.3390/ijms19102974. Review.

6.

The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies.

Arora L, Kumar AP, Arfuso F, Chng WJ, Sethi G.

Cancers (Basel). 2018 Sep 13;10(9). pii: E327. doi: 10.3390/cancers10090327. Review.

7.

Magnolol: A Neolignan from the Magnolia Family for the Prevention and Treatment of Cancer.

Ranaware AM, Banik K, Deshpande V, Padmavathi G, Roy NK, Sethi G, Fan L, Kumar AP, Kunnumakkara AB.

Int J Mol Sci. 2018 Aug 10;19(8). pii: E2362. doi: 10.3390/ijms19082362. Review.

8.

A Sensitive Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Nimbolide in Mouse Serum: Application to a Preclinical Pharmacokinetics Study.

Wang L, Phan DK, Syn N, Xiang X, Song H, Thuya WL, Yang S, Wong AL, Kumar AP, Yong WP, Sethi G, Ho PC, Goh BC.

Pharmaceutics. 2018 Aug 8;10(3). pii: E123. doi: 10.3390/pharmaceutics10030123.

9.

BRCA1 Interacting Protein COBRA1 Facilitates Adaptation to Castrate-Resistant Growth Conditions.

Yun H, Bedolla R, Horning A, Li R, Chiang HC, Huang TH, Reddick R, Olumi AF, Ghosh R, Kumar AP.

Int J Mol Sci. 2018 Jul 20;19(7). pii: E2104. doi: 10.3390/ijms19072104.

10.

Suppression of ribosomal protein RPS6KB1 by Nexrutine increases sensitivity of prostate tumors to radiation.

Hussain SS, Huang SB, Bedolla RG, Rivas P, Basler JW, Swanson GP, Hui-Ming Huang T, Narayanasamy G, Papanikolaou N, Miyamoto H, Yeh IT, Reddick RL, Pollock BH, Ghosh R, Kumar AP.

Cancer Lett. 2018 Oct 1;433:232-241. doi: 10.1016/j.canlet.2018.07.009. Epub 2018 Jul 9.

PMID:
30003927
11.

NGAL is Downregulated in Oral Squamous Cell Carcinoma and Leads to Increased Survival, Proliferation, Migration and Chemoresistance.

Monisha J, Roy NK, Padmavathi G, Banik K, Bordoloi D, Khwairakpam AD, Arfuso F, Chinnathambi A, Alahmadi TA, Alharbi SA, Sethi G, Kumar AP, Kunnumakkara AB.

Cancers (Basel). 2018 Jul 10;10(7). pii: E228. doi: 10.3390/cancers10070228.

12.

Role of RNF20 in cancer development and progression - a comprehensive review.

Sethi G, Shanmugam MK, Arfuso F, Kumar AP.

Biosci Rep. 2018 Jul 12;38(4). pii: BSR20171287. doi: 10.1042/BSR20171287. Print 2018 Aug 31. Review.

13.

Dataset on gene expression in the elderly after Mindfulness Awareness Practice or Health Education Program.

Lim HW, Saw WY, Feng L, Lee YK, Mahendran R, Cheah IK, Rawtaer I, Kumar AP, Kua EH, Mahendran R, Tan EC.

Data Brief. 2018 Mar 26;18:902-912. doi: 10.1016/j.dib.2018.03.086. eCollection 2018 Jun.

14.

Allosteric binding sites in Rab11 for potential drug candidates.

Kumar AP, Lukman S.

PLoS One. 2018 Jun 6;13(6):e0198632. doi: 10.1371/journal.pone.0198632. eCollection 2018.

15.

Formononetin-induced oxidative stress abrogates the activation of STAT3/5 signaling axis and suppresses the tumor growth in multiple myeloma preclinical model.

Kim C, Lee SG, Yang WM, Arfuso F, Um JY, Kumar AP, Bian J, Sethi G, Ahn KS.

Cancer Lett. 2018 Sep 1;431:123-141. doi: 10.1016/j.canlet.2018.05.038. Epub 2018 May 29.

PMID:
29857127
16.

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn.

Shanmugam MK, Arfuso F, Kumar AP, Wang L, Goh BC, Ahn KS, Bishayee A, Sethi G.

Pharmacol Res. 2018 Jul;133:213-214. doi: 10.1016/j.phrs.2018.05.004. Epub 2018 May 21. No abstract available.

PMID:
29792914
17.

Pro-Apoptotic and Anti-Cancer Properties of Diosgenin: A Comprehensive and Critical Review.

Sethi G, Shanmugam MK, Warrier S, Merarchi M, Arfuso F, Kumar AP, Bishayee A.

Nutrients. 2018 May 19;10(5). pii: E645. doi: 10.3390/nu10050645. Review.

18.

Antioxidant response elements: Discovery, classes, regulation and potential applications.

Raghunath A, Sundarraj K, Nagarajan R, Arfuso F, Bian J, Kumar AP, Sethi G, Perumal E.

Redox Biol. 2018 Jul;17:297-314. doi: 10.1016/j.redox.2018.05.002. Epub 2018 May 7. Review.

19.

Celastrol Attenuates the Invasion and Migration and Augments the Anticancer Effects of Bortezomib in a Xenograft Mouse Model of Multiple Myeloma.

Shanmugam MK, Ahn KS, Lee JH, Kannaiyan R, Mustafa N, Manu KA, Siveen KS, Sethi G, Chng WJ, Kumar AP.

Front Pharmacol. 2018 May 3;9:365. doi: 10.3389/fphar.2018.00365. eCollection 2018.

20.

Potential role of genipin in cancer therapy.

Shanmugam MK, Shen H, Tang FR, Arfuso F, Rajesh M, Wang L, Kumar AP, Bian J, Goh BC, Bishayee A, Sethi G.

Pharmacol Res. 2018 Jul;133:195-200. doi: 10.1016/j.phrs.2018.05.007. Epub 2018 May 24. Review.

PMID:
29758279
21.

Possible use of Punica granatum (Pomegranate) in cancer therapy.

Khwairakpam AD, Bordoloi D, Thakur KK, Monisha J, Arfuso F, Sethi G, Mishra S, Kumar AP, Kunnumakkara AB.

Pharmacol Res. 2018 Jul;133:53-64. doi: 10.1016/j.phrs.2018.04.021. Epub 2018 May 2. Review.

PMID:
29729421
22.

Ameliorative effect of chitosan-conjugated 17α-methyltestosterone on testicular development in Clarias batrachus.

Saha R, Bhat IA, Charan R, Purayil SBP, Krishna G, Kumar AP, Sharma R.

Anim Reprod Sci. 2018 Jun;193:245-254. doi: 10.1016/j.anireprosci.2018.04.078. Epub 2018 Apr 26.

PMID:
29728276
23.

Correction: Role of novel histone modifications in cancer.

Shanmugam MK, Arfuso F, Arumugam S, Chinnathambi A, Bian J, Warrier S, Wang LZ, Kumar AP, Ahn KS, Sethi G, Lakshmanan M.

Oncotarget. 2018 Apr 10;9(27):19460. doi: 10.18632/oncotarget.25152. eCollection 2018 Apr 10.

24.

Novel 1,3,4-Oxadiazole Induces Anticancer Activity by Targeting NF-κB in Hepatocellular Carcinoma Cells.

Mohan CD, Anilkumar NC, Rangappa S, Shanmugam MK, Mishra S, Chinnathambi A, Alharbi SA, Bhattacharjee A, Sethi G, Kumar AP, Basappa, Rangappa KS.

Front Oncol. 2018 Mar 19;8:42. doi: 10.3389/fonc.2018.00042. eCollection 2018.

25.

Role of novel histone modifications in cancer.

Shanmugam MK, Arfuso F, Arumugam S, Chinnathambi A, Jinsong B, Warrier S, Wang LZ, Kumar AP, Ahn KS, Sethi G, Lakshmanan M.

Oncotarget. 2017 Dec 17;9(13):11414-11426. doi: 10.18632/oncotarget.23356. eCollection 2018 Feb 16. Review. Erratum in: Oncotarget. 2018 Apr 10;9(27):19460.

26.

Corrigendum to "Tocotrienls: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics" [Drug Discov. Today 22 (December (12)) (2017) 1765-1781].

Kanchi MM, Shanmugam MK, Rane G, Sethi G, Kumar AP.

Drug Discov Today. 2018 Mar 7. pii: S1359-6446(18)30089-8. doi: 10.1016/j.drudis.2018.02.010. [Epub ahead of print] No abstract available.

PMID:
29524389
27.

Molecular cloning, characterization and expression profiling of galectin-9 gene from Labeo rohita (Hamilton, 1822).

Mushtaq Z, Krishnan R, Prasad KP, Bedekar MK, Kumar AP.

Fish Shellfish Immunol. 2018 May;76:287-292. doi: 10.1016/j.fsi.2018.02.037. Epub 2018 Mar 15.

PMID:
29477496
28.

Molecular targets and anti-cancer potential of escin.

Cheong DHJ, Arfuso F, Sethi G, Wang L, Hui KM, Kumar AP, Tran T.

Cancer Lett. 2018 May 28;422:1-8. doi: 10.1016/j.canlet.2018.02.027. Epub 2018 Feb 21.

PMID:
29474858
29.

Palmatine suppresses glutamine-mediated interaction between pancreatic cancer and stellate cells through simultaneous inhibition of survivin and COL1A1.

Chakravarthy D, Muñoz AR, Su A, Hwang RF, Keppler BR, Chan DE, Halff G, Ghosh R, Kumar AP.

Cancer Lett. 2018 Apr 10;419:103-115. doi: 10.1016/j.canlet.2018.01.057.

30.

Pancreatic cancer: Current status and Challenges.

Muñoz AR, Chakravarthy D, Gong J, Halff GA, Ghosh R, Kumar AP.

Curr Pharmacol Rep. 2017 Dec;3(6):396-408. doi: 10.1007/s40495-017-0112-3. Epub 2017 Oct 11.

31.

Corrigendum on "Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer" [Cancer Lett. 363 (1) (2015) 28-36].

Manu KA, Shanmugam MK, Ramachandran L, Li F, Siveen KS, Chinnathambi A, Zayed ME, Alharbi SA, Arfuso F, Kumar AP, Ahn KS, Sethi G.

Cancer Lett. 2018 Apr 28;420:259. doi: 10.1016/j.canlet.2018.01.003. Epub 2018 Jan 17. No abstract available.

PMID:
29338890
32.

Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironment.

Moraes LA, Kar S, Foo SL, Gu T, Toh YQ, Ampomah PB, Sachaphibulkij K, Yap G, Zharkova O, Lukman HM, Fairhurst AM, Kumar AP, Lim LHK.

Sci Rep. 2017 Dec 20;7(1):17925. doi: 10.1038/s41598-017-17622-5.

33.

Dual role of autophagy in hallmarks of cancer.

Singh SS, Vats S, Chia AY, Tan TZ, Deng S, Ong MS, Arfuso F, Yap CT, Goh BC, Sethi G, Huang RY, Shen HM, Manjithaya R, Kumar AP.

Oncogene. 2018 Mar;37(9):1142-1158. doi: 10.1038/s41388-017-0046-6. Epub 2017 Dec 19. Review.

PMID:
29255248
34.

Therapeutic potential of gambogic acid, a caged xanthone, to target cancer.

Banik K, Harsha C, Bordoloi D, Lalduhsaki Sailo B, Sethi G, Leong HC, Arfuso F, Mishra S, Wang L, Kumar AP, Kunnumakkara AB.

Cancer Lett. 2018 Mar 1;416:75-86. doi: 10.1016/j.canlet.2017.12.014. Epub 2017 Dec 13. Review.

PMID:
29246645
35.

Structural analysis of protein tyrosine phosphatase 1B reveals potentially druggable allosteric binding sites.

Kumar AP, Nguyen MN, Verma C, Lukman S.

Proteins. 2018 Mar;86(3):301-321. doi: 10.1002/prot.25440. Epub 2018 Jan 3.

PMID:
29235148
36.

Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle-Related Transcription and Attenuated Androgen Response.

Horning AM, Wang Y, Lin CK, Louie AD, Jadhav RR, Hung CN, Wang CM, Lin CL, Kirma NB, Liss MA, Kumar AP, Sun L, Liu Z, Chao WT, Wang Q, Jin VX, Chen CL, Huang TH.

Cancer Res. 2018 Feb 15;78(4):853-864. doi: 10.1158/0008-5472.CAN-17-1924. Epub 2017 Dec 12.

PMID:
29233929
37.

The Role of Resveratrol in Cancer Therapy.

Ko JH, Sethi G, Um JY, Shanmugam MK, Arfuso F, Kumar AP, Bishayee A, Ahn KS.

Int J Mol Sci. 2017 Dec 1;18(12). pii: E2589. doi: 10.3390/ijms18122589. Review.

38.

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn.

Shanmugam MK, Arfuso F, Kumar AP, Wang L, Goh BC, Ahn KS, Bishayee A, Sethi G.

Pharmacol Res. 2018 Mar;129:357-364. doi: 10.1016/j.phrs.2017.11.023. Epub 2017 Nov 21. Review.

PMID:
29162539
39.

Triple negative breast cancer in Asia: An insider's view.

Wang C, Kar S, Lai X, Cai W, Arfuso F, Sethi G, Lobie PE, Goh BC, Lim LHK, Hartman M, Chan CW, Lee SC, Tan SH, Kumar AP.

Cancer Treat Rev. 2018 Jan;62:29-38. doi: 10.1016/j.ctrv.2017.10.014. Epub 2017 Nov 10. Review.

PMID:
29154023
40.

SREBP-1c as a molecular bridge between lipogenesis and cell cycle progression of clear cell renal carcinoma.

Sethi G, Shanmugam MK, Kumar AP.

Biosci Rep. 2017 Dec 15;37(6). pii: BSR20171270. doi: 10.1042/BSR20171270. Print 2017 Dec 22. Review.

PMID:
29138263
41.

Short-chain fatty acid receptors inhibit invasive phenotypes in breast cancer cells.

Thirunavukkarasan M, Wang C, Rao A, Hind T, Teo YR, Siddiquee AA, Goghari MAI, Kumar AP, Herr DR.

PLoS One. 2017 Oct 19;12(10):e0186334. doi: 10.1371/journal.pone.0186334. eCollection 2017.

42.

Design and synthesis of benzimidazole-based Rho kinase inhibitors for the treatment of glaucoma.

Abbhi V, Saini L, Mishra S, Sethi G, Kumar AP, Piplani P.

Bioorg Med Chem. 2017 Nov 1;25(21):6071-6085. doi: 10.1016/j.bmc.2017.09.045. Epub 2017 Oct 4.

PMID:
29033348
43.

PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers.

Chen L, Yuan Y, Kar S, Kanchi MM, Arora S, Kim JE, Koh PF, Yousef E, Samy RP, Shanmugam MK, Tan TZ, Shin SW, Arfuso F, Shen HM, Yang H, Goh BC, Park JI, Gaboury L, Lobie PE, Sethi G, Lim LHK, Kumar AP.

Mol Cancer Ther. 2017 Nov;16(11):2528-2542. doi: 10.1158/1535-7163.MCT-16-0739. Epub 2017 Aug 15.

44.

Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators.

Bhuvanalakshmi G, Arfuso F, Kumar AP, Dharmarajan A, Warrier S.

Stem Cell Res Ther. 2017 Aug 14;8(1):185. doi: 10.1186/s13287-017-0638-7.

45.

Tocotrienols: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics.

Kanchi MM, Shanmugam MK, Rane G, Sethi G, Kumar AP.

Drug Discov Today. 2017 Dec;22(12):1765-1781. doi: 10.1016/j.drudis.2017.08.001. Epub 2017 Aug 5. Review. Erratum in: Drug Discov Today. 2018 Mar 7;:.

PMID:
28789906
46.

'Lnc'-ing Wnt in female reproductive cancers: therapeutic potential of long non-coding RNAs in Wnt signalling.

Ong MS, Cai W, Yuan Y, Leong HC, Tan TZ, Mohammad A, You ML, Arfuso F, Goh BC, Warrier S, Sethi G, Tolwinski NS, Lobie PE, Yap CT, Hooi SC, Huang RY, Kumar AP.

Br J Pharmacol. 2017 Dec;174(24):4684-4700. doi: 10.1111/bph.13958. Epub 2017 Aug 23. Review.

47.

Potential Role of Natural Compounds as Anti-Angiogenic Agents in Cancer.

Shanmugam MK, Warrier S, Kumar AP, Sethi G, Arfuso F.

Curr Vasc Pharmacol. 2017;15(6):503-519. doi: 10.2174/1570161115666170713094319. Review.

PMID:
28707601
48.

Art therapy and music reminiscence activity in the prevention of cognitive decline: study protocol for a randomized controlled trial.

Mahendran R, Rawtaer I, Fam J, Wong J, Kumar AP, Gandhi M, Jing KX, Feng L, Kua EH.

Trials. 2017 Jul 12;18(1):324. doi: 10.1186/s13063-017-2080-7.

49.

ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator.

Jahn A, Rane G, Paszkowski-Rogacz M, Sayols S, Bluhm A, Han CT, Draškovič I, Londoño-Vallejo JA, Kumar AP, Buchholz F, Butter F, Kappei D.

EMBO Rep. 2017 Jun;18(6):929-946. doi: 10.15252/embr.201744095. Epub 2017 May 12.

50.

Combination of Nexrutine and docetaxel suppresses NFκB-mediated activation of c-FLIP.

Zhang Y, Li L, Wang J, Cheng W, Zhang J, Li X, Zhang Z, Gong J, Ghosh R, Kumar AP, Xie J.

Mol Carcinog. 2017 Oct;56(10):2200-2209. doi: 10.1002/mc.22673. Epub 2017 Jun 15.

PMID:
28485511

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