Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 256

1.

A Sensitive Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Nimbolide in Mouse Serum: Application to a Preclinical Pharmacokinetics Study.

Wang L, Phan DK, Syn N, Xiang X, Song H, Thuya WL, Yang S, Wong AL, Kumar AP, Yong WP, Sethi G, Ho PC, Goh BC.

Pharmaceutics. 2018 Aug 8;10(3). pii: E123. doi: 10.3390/pharmaceutics10030123.

2.

BRCA1 Interacting Protein COBRA1 Facilitates Adaptation to Castrate-Resistant Growth Conditions.

Yun H, Bedolla R, Horning A, Li R, Chiang HC, Huang TH, Reddick R, Olumi AF, Ghosh R, Kumar AP.

Int J Mol Sci. 2018 Jul 20;19(7). pii: E2104. doi: 10.3390/ijms19072104.

3.

Suppression of ribosomal protein RPS6KB1 by Nexrutine increases sensitivity of prostate tumors to radiation.

Hussain SS, Huang SB, Bedolla RG, Rivas P, Basler JW, Swanson GP, Hui-Ming Huang T, Narayanasamy G, Papanikolaou N, Miyamoto H, Yeh IT, Reddick RL, Pollock BH, Ghosh R, Kumar AP.

Cancer Lett. 2018 Oct 1;433:232-241. doi: 10.1016/j.canlet.2018.07.009. Epub 2018 Jul 9.

PMID:
30003927
4.

NGAL is Downregulated in Oral Squamous Cell Carcinoma and Leads to Increased Survival, Proliferation, Migration and Chemoresistance.

Monisha J, Roy NK, Padmavathi G, Banik K, Bordoloi D, Khwairakpam AD, Arfuso F, Chinnathambi A, Alahmadi TA, Alharbi SA, Sethi G, Kumar AP, Kunnumakkara AB.

Cancers (Basel). 2018 Jul 10;10(7). pii: E228. doi: 10.3390/cancers10070228.

5.

Role of RNF20 in cancer development and progression - a comprehensive review.

Sethi G, Shanmugam MK, Arfuso F, Kumar AP.

Biosci Rep. 2018 Jul 12;38(4). pii: BSR20171287. doi: 10.1042/BSR20171287. Print 2018 Aug 31. Review.

6.

Dataset on gene expression in the elderly after Mindfulness Awareness Practice or Health Education Program.

Lim HW, Saw WY, Feng L, Lee YK, Mahendran R, Cheah IK, Rawtaer I, Kumar AP, Kua EH, Mahendran R, Tan EC.

Data Brief. 2018 Mar 26;18:902-912. doi: 10.1016/j.dib.2018.03.086. eCollection 2018 Jun.

7.

Allosteric binding sites in Rab11 for potential drug candidates.

Kumar AP, Lukman S.

PLoS One. 2018 Jun 6;13(6):e0198632. doi: 10.1371/journal.pone.0198632. eCollection 2018.

8.

Formononetin-induced oxidative stress abrogates the activation of STAT3/5 signaling axis and suppresses the tumor growth in multiple myeloma preclinical model.

Kim C, Lee SG, Yang WM, Arfuso F, Um JY, Kumar AP, Bian J, Sethi G, Ahn KS.

Cancer Lett. 2018 Sep 1;431:123-141. doi: 10.1016/j.canlet.2018.05.038. Epub 2018 May 29.

PMID:
29857127
9.

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn.

Shanmugam MK, Arfuso F, Kumar AP, Wang L, Goh BC, Ahn KS, Bishayee A, Sethi G.

Pharmacol Res. 2018 Jul;133:213-214. doi: 10.1016/j.phrs.2018.05.004. Epub 2018 May 21. No abstract available.

PMID:
29792914
10.

Pro-Apoptotic and Anti-Cancer Properties of Diosgenin: A Comprehensive and Critical Review.

Sethi G, Shanmugam MK, Warrier S, Merarchi M, Arfuso F, Kumar AP, Bishayee A.

Nutrients. 2018 May 19;10(5). pii: E645. doi: 10.3390/nu10050645. Review.

11.

Antioxidant response elements: Discovery, classes, regulation and potential applications.

Raghunath A, Sundarraj K, Nagarajan R, Arfuso F, Bian J, Kumar AP, Sethi G, Perumal E.

Redox Biol. 2018 Jul;17:297-314. doi: 10.1016/j.redox.2018.05.002. Epub 2018 May 7. Review.

12.

Celastrol Attenuates the Invasion and Migration and Augments the Anticancer Effects of Bortezomib in a Xenograft Mouse Model of Multiple Myeloma.

Shanmugam MK, Ahn KS, Lee JH, Kannaiyan R, Mustafa N, Manu KA, Siveen KS, Sethi G, Chng WJ, Kumar AP.

Front Pharmacol. 2018 May 3;9:365. doi: 10.3389/fphar.2018.00365. eCollection 2018.

13.

Potential role of genipin in cancer therapy.

Shanmugam MK, Shen H, Tang FR, Arfuso F, Rajesh M, Wang L, Kumar AP, Bian J, Goh BC, Bishayee A, Sethi G.

Pharmacol Res. 2018 Jul;133:195-200. doi: 10.1016/j.phrs.2018.05.007. Epub 2018 May 24. Review.

PMID:
29758279
14.

Possible use of Punica granatum (Pomegranate) in cancer therapy.

Khwairakpam AD, Bordoloi D, Thakur KK, Monisha J, Arfuso F, Sethi G, Mishra S, Kumar AP, Kunnumakkara AB.

Pharmacol Res. 2018 Jul;133:53-64. doi: 10.1016/j.phrs.2018.04.021. Epub 2018 May 2. Review.

PMID:
29729421
15.

Ameliorative effect of chitosan-conjugated 17α-methyltestosterone on testicular development in Clarias batrachus.

Saha R, Bhat IA, Charan R, Purayil SBP, Krishna G, Kumar AP, Sharma R.

Anim Reprod Sci. 2018 Jun;193:245-254. doi: 10.1016/j.anireprosci.2018.04.078. Epub 2018 Apr 26.

PMID:
29728276
16.

Correction: Role of novel histone modifications in cancer.

Shanmugam MK, Arfuso F, Arumugam S, Chinnathambi A, Bian J, Warrier S, Wang LZ, Kumar AP, Ahn KS, Sethi G, Lakshmanan M.

Oncotarget. 2018 Apr 10;9(27):19460. doi: 10.18632/oncotarget.25152. eCollection 2018 Apr 10.

17.

Novel 1,3,4-Oxadiazole Induces Anticancer Activity by Targeting NF-κB in Hepatocellular Carcinoma Cells.

Mohan CD, Anilkumar NC, Rangappa S, Shanmugam MK, Mishra S, Chinnathambi A, Alharbi SA, Bhattacharjee A, Sethi G, Kumar AP, Basappa, Rangappa KS.

Front Oncol. 2018 Mar 19;8:42. doi: 10.3389/fonc.2018.00042. eCollection 2018.

18.

Role of novel histone modifications in cancer.

Shanmugam MK, Arfuso F, Arumugam S, Chinnathambi A, Jinsong B, Warrier S, Wang LZ, Kumar AP, Ahn KS, Sethi G, Lakshmanan M.

Oncotarget. 2017 Dec 17;9(13):11414-11426. doi: 10.18632/oncotarget.23356. eCollection 2018 Feb 16. Review. Erratum in: Oncotarget. 2018 Apr 10;9(27):19460.

19.

Corrigendum to "Tocotrienls: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics" [Drug Discov. Today 22 (December (12)) (2017) 1765-1781].

Kanchi MM, Shanmugam MK, Rane G, Sethi G, Kumar AP.

Drug Discov Today. 2018 Mar 7. pii: S1359-6446(18)30089-8. doi: 10.1016/j.drudis.2018.02.010. [Epub ahead of print] No abstract available.

PMID:
29524389
20.

Molecular cloning, characterization and expression profiling of galectin-9 gene from Labeo rohita (Hamilton, 1822).

Mushtaq Z, Krishnan R, Prasad KP, Bedekar MK, Kumar AP.

Fish Shellfish Immunol. 2018 May;76:287-292. doi: 10.1016/j.fsi.2018.02.037. Epub 2018 Mar 15.

PMID:
29477496
21.

Molecular targets and anti-cancer potential of escin.

Cheong DHJ, Arfuso F, Sethi G, Wang L, Hui KM, Kumar AP, Tran T.

Cancer Lett. 2018 May 28;422:1-8. doi: 10.1016/j.canlet.2018.02.027. Epub 2018 Feb 21.

PMID:
29474858
22.

Palmatine suppresses glutamine-mediated interaction between pancreatic cancer and stellate cells through simultaneous inhibition of survivin and COL1A1.

Chakravarthy D, Muñoz AR, Su A, Hwang RF, Keppler BR, Chan DE, Halff G, Ghosh R, Kumar AP.

Cancer Lett. 2018 Apr 10;419:103-115. doi: 10.1016/j.canlet.2018.01.057.

23.

Pancreatic cancer: Current status and Challenges.

Muñoz AR, Chakravarthy D, Gong J, Halff GA, Ghosh R, Kumar AP.

Curr Pharmacol Rep. 2017 Dec;3(6):396-408. doi: 10.1007/s40495-017-0112-3. Epub 2017 Oct 11.

PMID:
29404265
24.

Corrigendum on "Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer" [Cancer Lett. 363 (1) (2015) 28-36].

Manu KA, Shanmugam MK, Ramachandran L, Li F, Siveen KS, Chinnathambi A, Zayed ME, Alharbi SA, Arfuso F, Kumar AP, Ahn KS, Sethi G.

Cancer Lett. 2018 Apr 28;420:259. doi: 10.1016/j.canlet.2018.01.003. Epub 2018 Jan 17. No abstract available.

PMID:
29338890
25.

Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironment.

Moraes LA, Kar S, Foo SL, Gu T, Toh YQ, Ampomah PB, Sachaphibulkij K, Yap G, Zharkova O, Lukman HM, Fairhurst AM, Kumar AP, Lim LHK.

Sci Rep. 2017 Dec 20;7(1):17925. doi: 10.1038/s41598-017-17622-5.

26.

Dual role of autophagy in hallmarks of cancer.

Singh SS, Vats S, Chia AY, Tan TZ, Deng S, Ong MS, Arfuso F, Yap CT, Goh BC, Sethi G, Huang RY, Shen HM, Manjithaya R, Kumar AP.

Oncogene. 2018 Mar;37(9):1142-1158. doi: 10.1038/s41388-017-0046-6. Epub 2017 Dec 19. Review.

PMID:
29255248
27.

Therapeutic potential of gambogic acid, a caged xanthone, to target cancer.

Banik K, Harsha C, Bordoloi D, Lalduhsaki Sailo B, Sethi G, Leong HC, Arfuso F, Mishra S, Wang L, Kumar AP, Kunnumakkara AB.

Cancer Lett. 2018 Mar 1;416:75-86. doi: 10.1016/j.canlet.2017.12.014. Epub 2017 Dec 13.

PMID:
29246645
28.

Structural analysis of protein tyrosine phosphatase 1B reveals potentially druggable allosteric binding sites.

Kumar AP, Nguyen MN, Verma C, Lukman S.

Proteins. 2018 Mar;86(3):301-321. doi: 10.1002/prot.25440. Epub 2018 Jan 3.

PMID:
29235148
29.

Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle-Related Transcription and Attenuated Androgen Response.

Horning AM, Wang Y, Lin CK, Louie AD, Jadhav RR, Hung CN, Wang CM, Lin CL, Kirma NB, Liss MA, Kumar AP, Sun L, Liu Z, Chao WT, Wang Q, Jin VX, Chen CL, Huang TH.

Cancer Res. 2018 Feb 15;78(4):853-864. doi: 10.1158/0008-5472.CAN-17-1924. Epub 2017 Dec 12.

PMID:
29233929
30.

The Role of Resveratrol in Cancer Therapy.

Ko JH, Sethi G, Um JY, Shanmugam MK, Arfuso F, Kumar AP, Bishayee A, Ahn KS.

Int J Mol Sci. 2017 Dec 1;18(12). pii: E2589. doi: 10.3390/ijms18122589. Review.

31.

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn.

Shanmugam MK, Arfuso F, Kumar AP, Wang L, Goh BC, Ahn KS, Bishayee A, Sethi G.

Pharmacol Res. 2018 Mar;129:357-364. doi: 10.1016/j.phrs.2017.11.023. Epub 2017 Nov 21. Review.

PMID:
29162539
32.

Triple negative breast cancer in Asia: An insider's view.

Wang C, Kar S, Lai X, Cai W, Arfuso F, Sethi G, Lobie PE, Goh BC, Lim LHK, Hartman M, Chan CW, Lee SC, Tan SH, Kumar AP.

Cancer Treat Rev. 2018 Jan;62:29-38. doi: 10.1016/j.ctrv.2017.10.014. Epub 2017 Nov 10. Review.

PMID:
29154023
33.

SREBP-1c as a molecular bridge between lipogenesis and cell cycle progression of clear cell renal carcinoma.

Sethi G, Shanmugam MK, Kumar AP.

Biosci Rep. 2017 Dec 15;37(6). pii: BSR20171270. doi: 10.1042/BSR20171270. Print 2017 Dec 22. Review.

PMID:
29138263
34.

Short-chain fatty acid receptors inhibit invasive phenotypes in breast cancer cells.

Thirunavukkarasan M, Wang C, Rao A, Hind T, Teo YR, Siddiquee AA, Goghari MAI, Kumar AP, Herr DR.

PLoS One. 2017 Oct 19;12(10):e0186334. doi: 10.1371/journal.pone.0186334. eCollection 2017.

35.

Design and synthesis of benzimidazole-based Rho kinase inhibitors for the treatment of glaucoma.

Abbhi V, Saini L, Mishra S, Sethi G, Kumar AP, Piplani P.

Bioorg Med Chem. 2017 Nov 1;25(21):6071-6085. doi: 10.1016/j.bmc.2017.09.045. Epub 2017 Oct 4.

PMID:
29033348
36.

PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers.

Chen L, Yuan Y, Kar S, Kanchi MM, Arora S, Kim JE, Koh PF, Yousef E, Samy RP, Shanmugam MK, Tan TZ, Shin SW, Arfuso F, Shen HM, Yang H, Goh BC, Park JI, Gaboury L, Lobie PE, Sethi G, Lim LHK, Kumar AP.

Mol Cancer Ther. 2017 Nov;16(11):2528-2542. doi: 10.1158/1535-7163.MCT-16-0739. Epub 2017 Aug 15.

PMID:
29021293
37.

Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators.

Bhuvanalakshmi G, Arfuso F, Kumar AP, Dharmarajan A, Warrier S.

Stem Cell Res Ther. 2017 Aug 14;8(1):185. doi: 10.1186/s13287-017-0638-7.

38.

Tocotrienols: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics.

Kanchi MM, Shanmugam MK, Rane G, Sethi G, Kumar AP.

Drug Discov Today. 2017 Dec;22(12):1765-1781. doi: 10.1016/j.drudis.2017.08.001. Epub 2017 Aug 5. Review. Erratum in: Drug Discov Today. 2018 Mar 7;:.

PMID:
28789906
39.

'Lnc'-ing Wnt in female reproductive cancers: therapeutic potential of long non-coding RNAs in Wnt signalling.

Ong MS, Cai W, Yuan Y, Leong HC, Tan TZ, Mohammad A, You ML, Arfuso F, Goh BC, Warrier S, Sethi G, Tolwinski NS, Lobie PE, Yap CT, Hooi SC, Huang RY, Kumar AP.

Br J Pharmacol. 2017 Dec;174(24):4684-4700. doi: 10.1111/bph.13958. Epub 2017 Aug 23. Review.

PMID:
28736855
40.

Potential Role of Natural Compounds as Anti-Angiogenic Agents in Cancer.

Shanmugam MK, Warrier S, Kumar AP, Sethi G, Arfuso F.

Curr Vasc Pharmacol. 2017;15(6):503-519. doi: 10.2174/1570161115666170713094319. Review.

PMID:
28707601
41.

Art therapy and music reminiscence activity in the prevention of cognitive decline: study protocol for a randomized controlled trial.

Mahendran R, Rawtaer I, Fam J, Wong J, Kumar AP, Gandhi M, Jing KX, Feng L, Kua EH.

Trials. 2017 Jul 12;18(1):324. doi: 10.1186/s13063-017-2080-7.

42.

ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator.

Jahn A, Rane G, Paszkowski-Rogacz M, Sayols S, Bluhm A, Han CT, Draškovič I, Londoño-Vallejo JA, Kumar AP, Buchholz F, Butter F, Kappei D.

EMBO Rep. 2017 Jun;18(6):929-946. doi: 10.15252/embr.201744095. Epub 2017 May 12.

43.

Combination of Nexrutine and docetaxel suppresses NFκB-mediated activation of c-FLIP.

Zhang Y, Li L, Wang J, Cheng W, Zhang J, Li X, Zhang Z, Gong J, Ghosh R, Kumar AP, Xie J.

Mol Carcinog. 2017 Oct;56(10):2200-2209. doi: 10.1002/mc.22673. Epub 2017 Jun 15.

PMID:
28485511
44.

Molecular Targets of Ascochlorin and Its Derivatives for Cancer Therapy.

Min-Wen JC, Yan-Jiang BC, Mishra S, Dai X, Magae J, Shyh-Chang N, Kumar AP, Sethi G.

Adv Protein Chem Struct Biol. 2017;108:199-225. doi: 10.1016/bs.apcsb.2017.01.001. Epub 2017 Feb 15. Review.

PMID:
28427561
45.

Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4.

Bhuvanalakshmi G, Basappa, Rangappa KS, Dharmarajan A, Sethi G, Kumar AP, Warrier S.

Front Pharmacol. 2017 Mar 20;8:124. doi: 10.3389/fphar.2017.00124. eCollection 2017.

46.

Wnt signaling in triple-negative breast cancer.

Pohl SG, Brook N, Agostino M, Arfuso F, Kumar AP, Dharmarajan A.

Oncogenesis. 2017 Apr 3;6(4):e310. doi: 10.1038/oncsis.2017.14. Review.

47.

Novel aromatase inhibitors selection using induced fit docking and extra precision methods: Potential clinical use in ER-alpha-positive breast cancer.

Kumavath R, Azad M, Devarapalli P, Tiwari S, Kar S, Barh D, Azevedo V, Kumar AP.

Bioinformation. 2016 Oct 10;12(6):324-331. doi: 10.6026/97320630012324. eCollection 2016.

48.

A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma.

Dai X, Wang L, Deivasigamni A, Looi CY, Karthikeyan C, Trivedi P, Chinnathambi A, Alharbi SA, Arfuso F, Dharmarajan A, Goh BC, Hui KM, Kumar AP, Mustafa MR, Sethi G.

Oncotarget. 2017 Feb 21;8(8):12831-12842. doi: 10.18632/oncotarget.14606.

49.

Cardamonin represses proliferation, invasion, and causes apoptosis through the modulation of signal transducer and activator of transcription 3 pathway in prostate cancer.

Zhang J, Sikka S, Siveen KS, Lee JH, Um JY, Kumar AP, Chinnathambi A, Alharbi SA, Basappa, Rangappa KS, Sethi G, Ahn KS.

Apoptosis. 2017 Jan;22(1):158-168. doi: 10.1007/s10495-016-1313-7.

PMID:
27900636
50.

Identification of natural peptides as a new class of antimalarial drugs by in silico approaches.

Samy RP, Foo SL, Franco OL, Stiles BG, Kumar AP, Sethi G, Lim LH.

Front Biosci (Schol Ed). 2017 Jan 1;9:88-110. Review.

PMID:
27814577

Supplemental Content

Loading ...
Support Center