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Items: 1 to 50 of 281

1.

Autophagy Modulators: Mechanistic Aspects and Drug Delivery Systems.

Tavakol S, Ashrafizadeh M, Deng S, Azarian M, Abdoli A, Motavaf M, Poormoghadam D, Khanbabaei H, Afshar EG, Mandegary A, Pardakhty A, Yap CT, Mohammadinejad R, Kumar AP.

Biomolecules. 2019 Sep 25;9(10). pii: E530. doi: 10.3390/biom9100530. Review.

2.

c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression.

Sim WJ, Iyengar PV, Lama D, Lui SKL, Ng HC, Haviv-Shapira L, Domany E, Kappei D, Tan TZ, Saie A, Jaynes PW, Verma CS, Kumar AP, Rouanne M, Ha HK, Radulescu C, Ten Dijke P, Eichhorn PJA, Thiery JP.

Nat Commun. 2019 Sep 25;10(1):4349. doi: 10.1038/s41467-019-12241-2.

3.

Nexrutine® preserves muscle mass similar to exercise in prostate cancer mouse model.

Patel DI, Wallace D, Abuchowski K, Rivas P, Gallegos A, Musi N, Kumar AP.

Physiol Rep. 2019 Aug;7(16):e14217. doi: 10.14814/phy2.14217.

4.

Computational and Experimental Approaches to Design Inhibitors of Amylin Aggregation.

Kumar AP, Lee S, Lukman S.

Curr Drug Targets. 2019 Jul 19. doi: 10.2174/1389450120666190719164316. [Epub ahead of print]

PMID:
31333136
5.

Incidence of Type 2 Diabetes is Higher among Men with Persistent Impaired Glucose Tolerance than in Transient Impaired Glucose Tolerance - A 5 year Follow up Study.

Raghavan A, Nanditha A, Snehalatha C, Vinitha R, Susairaj P, Simon M, Selvam S, Satheesh K, Ram J, Kumar APN, Godsland IF, Oliver N, Johnston DG, Ramachandran A.

J Assoc Physicians India. 2018 Oct;66(10):22-26.

PMID:
31317702
6.

Anti-cancer effects of oxymatrine are mediated through multiple molecular mechanism(s) in tumor models.

Halim CE, Xinjing SL, Fan L, Bailey Vitarbo J, Arfuso F, Tan CH, Narula AS, Kumar AP, Sethi G, Ahn KS.

Pharmacol Res. 2019 Sep;147:104327. doi: 10.1016/j.phrs.2019.104327. Epub 2019 Jul 5. Review.

PMID:
31283981
7.

Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma.

Roy NK, Monisha J, Padmavathi G, Lalhruaitluanga H, Kumar NS, Singh AK, Bordoloi D, Baruah MN, Ahmed GN, Longkumar I, Arfuso F, Kumar AP, Kunnumakkara AB.

Biomolecules. 2019 Jun 27;9(7). pii: E253. doi: 10.3390/biom9070253.

8.

Histoplasmosis, heart failure, hemolysis and haemophagocytic lymphohistiocytosis.

Gupta N, Vinod KS, Mittal A, Kumar APA, Kumar A, Wig N.

Pan Afr Med J. 2019 Jan 23;32:43. doi: 10.11604/pamj.2019.32.43.14954. eCollection 2019.

9.

Contextual role of E2F1 in suppression of melanoma cell motility and invasiveness.

Meng P, Bedolla RG, Yun H, Fitzpatrick JE, Kumar AP, Ghosh R.

Mol Carcinog. 2019 Sep;58(9):1701-1710. doi: 10.1002/mc.23043. Epub 2019 May 23.

PMID:
31124185
10.

Biopharmacological considerations for accelerating drug development of deguelin, a rotenoid with potent chemotherapeutic and chemopreventive potential.

Varughese RS, Lam WS, Marican AABH, Viganeshwari SH, Bhave AS, Syn NL, Wang J, Wong AL, Kumar AP, Lobie PE, Lee SC, Sethi G, Goh BC, Wang L.

Cancer. 2019 Jun 1;125(11):1789-1798. doi: 10.1002/cncr.32069. Epub 2019 Apr 1. Review.

PMID:
30933320
11.

Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases.

Mishra S, Verma SS, Rai V, Awasthee N, Chava S, Hui KM, Kumar AP, Challagundla KB, Sethi G, Gupta SC.

Cell Mol Life Sci. 2019 May;76(10):1947-1966. doi: 10.1007/s00018-019-03053-0. Epub 2019 Mar 16. Review.

PMID:
30879091
12.

Receptor tyrosine kinase recepteur d'origine nantais as predictive marker for aggressive prostate cancer in African Americans.

Bedolla RG, Shah DP, Huang SB, Reddick RL, Ghosh R, Kumar AP.

Mol Carcinog. 2019 Jun;58(6):854-861. doi: 10.1002/mc.23002. Epub 2019 Mar 11.

PMID:
30859654
13.

FBXW7 in Cancer: What Has Been Unraveled Thus Far?

Sailo BL, Banik K, Girisa S, Bordoloi D, Fan L, Halim CE, Wang H, Kumar AP, Zheng D, Mao X, Sethi G, Kunnumakkara AB.

Cancers (Basel). 2019 Feb 19;11(2). pii: E246. doi: 10.3390/cancers11020246. Review.

14.

Targeting autophagy using natural compounds for cancer prevention and therapy.

Deng S, Shanmugam MK, Kumar AP, Yap CT, Sethi G, Bishayee A.

Cancer. 2019 Apr 15;125(8):1228-1246. doi: 10.1002/cncr.31978. Epub 2019 Feb 12. Review.

PMID:
30748003
15.

The expanding roles of long non-coding RNAs in the regulation of cancer stem cells.

Ma Z, Wang YY, Xin HW, Wang L, Arfuso F, Dharmarajan A, Kumar AP, Wang H, Tang FR, Warrier S, Tergaonkar V, Sethi G.

Int J Biochem Cell Biol. 2019 Mar;108:17-20. doi: 10.1016/j.biocel.2019.01.003. Epub 2019 Jan 7. Review.

PMID:
30630112
16.

Haptoglobin improves acute phase response and endotoxin tolerance in response to bacterial LPS.

Raju SM, Kumar AP, Yadav AN, Rajkumar K, Mvs S, Burgula S.

Immunol Lett. 2019 Mar;207:17-27. doi: 10.1016/j.imlet.2019.01.002. Epub 2019 Jan 6.

PMID:
30625342
17.

Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma.

Bhuvanalakshmi G, Gamit N, Patil M, Arfuso F, Sethi G, Dharmarajan A, Kumar AP, Warrier S.

Cancers (Basel). 2018 Dec 27;11(1). pii: E25. doi: 10.3390/cancers11010025.

18.

Thymoquinone Inhibits Bone Metastasis of Breast Cancer Cells Through Abrogation of the CXCR4 Signaling Axis.

Shanmugam MK, Ahn KS, Hsu A, Woo CC, Yuan Y, Tan KHB, Chinnathambi A, Alahmadi TA, Alharbi SA, Koh APF, Arfuso F, Huang RY, Lim LHK, Sethi G, Kumar AP.

Front Pharmacol. 2018 Dec 4;9:1294. doi: 10.3389/fphar.2018.01294. eCollection 2018.

19.

Cefixime-associated acute generalized exanthematous pustulosis: Rare cases in India.

Kumar V, Kalaiselvan V, Kumar AP, Saurabh A, Thota P, Sidhu S, Medhi B.

Indian J Pharmacol. 2018 Jul-Aug;50(4):204-207. doi: 10.4103/ijp.IJP_673_17.

20.

N-Substituted Pyrido-1,4-Oxazin-3-Ones Induce Apoptosis of Hepatocellular Carcinoma Cells by Targeting NF-κB Signaling Pathway.

Mohan CD, Bharathkumar H, Dukanya, Rangappa S, Shanmugam MK, Chinnathambi A, Alharbi SA, Alahmadi TA, Bhattacharjee A, Lobie PE, Deivasigamani A, Hui KM, Sethi G, Basappa, Rangappa KS, Kumar AP.

Front Pharmacol. 2018 Nov 5;9:1125. doi: 10.3389/fphar.2018.01125. eCollection 2018.

21.
22.

A Review on Liquid Chromatography-Tandem Mass Spectrometry Methods for Rapid Quantification of Oncology Drugs.

Wong AL, Xiang X, Ong PS, Mitchell EQY, Syn N, Wee I, Kumar AP, Yong WP, Sethi G, Goh BC, Ho PC, Wang L.

Pharmaceutics. 2018 Nov 8;10(4). pii: E221. doi: 10.3390/pharmaceutics10040221. Review.

23.

TIPE Family of Proteins and Its Implications in Different Chronic Diseases.

Bordoloi D, Banik K, Shabnam B, Padmavathi G, Monisha J, Arfuso F, Dharmarajan A, Mao X, Lim LHK, Wang L, Fan L, Hui KM, Kumar AP, Sethi G, Kunnumakkara AB.

Int J Mol Sci. 2018 Sep 29;19(10). pii: E2974. doi: 10.3390/ijms19102974. Review.

24.

The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies.

Arora L, Kumar AP, Arfuso F, Chng WJ, Sethi G.

Cancers (Basel). 2018 Sep 13;10(9). pii: E327. doi: 10.3390/cancers10090327. Review.

25.

Magnolol: A Neolignan from the Magnolia Family for the Prevention and Treatment of Cancer.

Ranaware AM, Banik K, Deshpande V, Padmavathi G, Roy NK, Sethi G, Fan L, Kumar AP, Kunnumakkara AB.

Int J Mol Sci. 2018 Aug 10;19(8). pii: E2362. doi: 10.3390/ijms19082362. Review.

26.

A Sensitive Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Nimbolide in Mouse Serum: Application to a Preclinical Pharmacokinetics Study.

Wang L, Phan DK, Syn N, Xiang X, Song H, Thuya WL, Yang S, Wong AL, Kumar AP, Yong WP, Sethi G, Ho PC, Goh BC.

Pharmaceutics. 2018 Aug 8;10(3). pii: E123. doi: 10.3390/pharmaceutics10030123.

27.

BRCA1 Interacting Protein COBRA1 Facilitates Adaptation to Castrate-Resistant Growth Conditions.

Yun H, Bedolla R, Horning A, Li R, Chiang HC, Huang TH, Reddick R, Olumi AF, Ghosh R, Kumar AP.

Int J Mol Sci. 2018 Jul 20;19(7). pii: E2104. doi: 10.3390/ijms19072104.

28.

Suppression of ribosomal protein RPS6KB1 by Nexrutine increases sensitivity of prostate tumors to radiation.

Hussain SS, Huang SB, Bedolla RG, Rivas P, Basler JW, Swanson GP, Hui-Ming Huang T, Narayanasamy G, Papanikolaou N, Miyamoto H, Yeh IT, Reddick RL, Pollock BH, Ghosh R, Kumar AP.

Cancer Lett. 2018 Oct 1;433:232-241. doi: 10.1016/j.canlet.2018.07.009. Epub 2018 Jul 9.

PMID:
30003927
29.

NGAL is Downregulated in Oral Squamous Cell Carcinoma and Leads to Increased Survival, Proliferation, Migration and Chemoresistance.

Monisha J, Roy NK, Padmavathi G, Banik K, Bordoloi D, Khwairakpam AD, Arfuso F, Chinnathambi A, Alahmadi TA, Alharbi SA, Sethi G, Kumar AP, Kunnumakkara AB.

Cancers (Basel). 2018 Jul 10;10(7). pii: E228. doi: 10.3390/cancers10070228.

30.

Role of RNF20 in cancer development and progression - a comprehensive review.

Sethi G, Shanmugam MK, Arfuso F, Kumar AP.

Biosci Rep. 2018 Jul 12;38(4). pii: BSR20171287. doi: 10.1042/BSR20171287. Print 2018 Aug 31. Review.

31.

Dataset on gene expression in the elderly after Mindfulness Awareness Practice or Health Education Program.

Lim HW, Saw WY, Feng L, Lee YK, Mahendran R, Cheah IK, Rawtaer I, Kumar AP, Kua EH, Mahendran R, Tan EC.

Data Brief. 2018 Mar 26;18:902-912. doi: 10.1016/j.dib.2018.03.086. eCollection 2018 Jun.

32.

Allosteric binding sites in Rab11 for potential drug candidates.

Kumar AP, Lukman S.

PLoS One. 2018 Jun 6;13(6):e0198632. doi: 10.1371/journal.pone.0198632. eCollection 2018.

33.

Formononetin-induced oxidative stress abrogates the activation of STAT3/5 signaling axis and suppresses the tumor growth in multiple myeloma preclinical model.

Kim C, Lee SG, Yang WM, Arfuso F, Um JY, Kumar AP, Bian J, Sethi G, Ahn KS.

Cancer Lett. 2018 Sep 1;431:123-141. doi: 10.1016/j.canlet.2018.05.038. Epub 2018 May 29.

PMID:
29857127
34.

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn.

Shanmugam MK, Arfuso F, Kumar AP, Wang L, Goh BC, Ahn KS, Bishayee A, Sethi G.

Pharmacol Res. 2018 Jul;133:213-214. doi: 10.1016/j.phrs.2018.05.004. Epub 2018 May 21. No abstract available.

PMID:
29792914
35.

Pro-Apoptotic and Anti-Cancer Properties of Diosgenin: A Comprehensive and Critical Review.

Sethi G, Shanmugam MK, Warrier S, Merarchi M, Arfuso F, Kumar AP, Bishayee A.

Nutrients. 2018 May 19;10(5). pii: E645. doi: 10.3390/nu10050645. Review.

36.

Antioxidant response elements: Discovery, classes, regulation and potential applications.

Raghunath A, Sundarraj K, Nagarajan R, Arfuso F, Bian J, Kumar AP, Sethi G, Perumal E.

Redox Biol. 2018 Jul;17:297-314. doi: 10.1016/j.redox.2018.05.002. Epub 2018 May 7. Review.

37.

Celastrol Attenuates the Invasion and Migration and Augments the Anticancer Effects of Bortezomib in a Xenograft Mouse Model of Multiple Myeloma.

Shanmugam MK, Ahn KS, Lee JH, Kannaiyan R, Mustafa N, Manu KA, Siveen KS, Sethi G, Chng WJ, Kumar AP.

Front Pharmacol. 2018 May 3;9:365. doi: 10.3389/fphar.2018.00365. eCollection 2018.

38.

Potential role of genipin in cancer therapy.

Shanmugam MK, Shen H, Tang FR, Arfuso F, Rajesh M, Wang L, Kumar AP, Bian J, Goh BC, Bishayee A, Sethi G.

Pharmacol Res. 2018 Jul;133:195-200. doi: 10.1016/j.phrs.2018.05.007. Epub 2018 May 24. Review.

PMID:
29758279
39.

Possible use of Punica granatum (Pomegranate) in cancer therapy.

Khwairakpam AD, Bordoloi D, Thakur KK, Monisha J, Arfuso F, Sethi G, Mishra S, Kumar AP, Kunnumakkara AB.

Pharmacol Res. 2018 Jul;133:53-64. doi: 10.1016/j.phrs.2018.04.021. Epub 2018 May 2. Review.

PMID:
29729421
40.

Ameliorative effect of chitosan-conjugated 17α-methyltestosterone on testicular development in Clarias batrachus.

Saha R, Bhat IA, Charan R, Purayil SBP, Krishna G, Kumar AP, Sharma R.

Anim Reprod Sci. 2018 Jun;193:245-254. doi: 10.1016/j.anireprosci.2018.04.078. Epub 2018 Apr 26.

PMID:
29728276
41.

Correction: Role of novel histone modifications in cancer.

Shanmugam MK, Arfuso F, Arumugam S, Chinnathambi A, Bian J, Warrier S, Wang LZ, Kumar AP, Ahn KS, Sethi G, Lakshmanan M.

Oncotarget. 2018 Apr 10;9(27):19460. doi: 10.18632/oncotarget.25152. eCollection 2018 Apr 10.

42.

Novel 1,3,4-Oxadiazole Induces Anticancer Activity by Targeting NF-κB in Hepatocellular Carcinoma Cells.

Mohan CD, Anilkumar NC, Rangappa S, Shanmugam MK, Mishra S, Chinnathambi A, Alharbi SA, Bhattacharjee A, Sethi G, Kumar AP, Basappa, Rangappa KS.

Front Oncol. 2018 Mar 19;8:42. doi: 10.3389/fonc.2018.00042. eCollection 2018.

43.

Role of novel histone modifications in cancer.

Shanmugam MK, Arfuso F, Arumugam S, Chinnathambi A, Jinsong B, Warrier S, Wang LZ, Kumar AP, Ahn KS, Sethi G, Lakshmanan M.

Oncotarget. 2017 Dec 17;9(13):11414-11426. doi: 10.18632/oncotarget.23356. eCollection 2018 Feb 16. Review. Erratum in: Oncotarget. 2018 Apr 10;9(27):19460.

44.

Corrigendum to "Tocotrienols: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics" [Drug Discov. Today 22 (December (12)) (2017) 1765-1781].

Kanchi MM, Shanmugam MK, Rane G, Sethi G, Kumar AP.

Drug Discov Today. 2019 Jul;24(7):1421. doi: 10.1016/j.drudis.2018.02.010. Epub 2018 Mar 7. No abstract available.

PMID:
29524389
45.

Molecular cloning, characterization and expression profiling of galectin-9 gene from Labeo rohita (Hamilton, 1822).

Mushtaq Z, Krishnan R, Prasad KP, Bedekar MK, Kumar AP.

Fish Shellfish Immunol. 2018 May;76:287-292. doi: 10.1016/j.fsi.2018.02.037. Epub 2018 Mar 15.

PMID:
29477496
46.

Molecular targets and anti-cancer potential of escin.

Cheong DHJ, Arfuso F, Sethi G, Wang L, Hui KM, Kumar AP, Tran T.

Cancer Lett. 2018 May 28;422:1-8. doi: 10.1016/j.canlet.2018.02.027. Epub 2018 Feb 21. Review.

PMID:
29474858
47.

Palmatine suppresses glutamine-mediated interaction between pancreatic cancer and stellate cells through simultaneous inhibition of survivin and COL1A1.

Chakravarthy D, Muñoz AR, Su A, Hwang RF, Keppler BR, Chan DE, Halff G, Ghosh R, Kumar AP.

Cancer Lett. 2018 Apr 10;419:103-115. doi: 10.1016/j.canlet.2018.01.057.

48.

Pancreatic cancer: Current status and Challenges.

Muñoz AR, Chakravarthy D, Gong J, Halff GA, Ghosh R, Kumar AP.

Curr Pharmacol Rep. 2017 Dec;3(6):396-408. doi: 10.1007/s40495-017-0112-3. Epub 2017 Oct 11.

49.

Corrigendum on "Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer" [Cancer Lett. 363 (1) (2015) 28-36].

Manu KA, Shanmugam MK, Ramachandran L, Li F, Siveen KS, Chinnathambi A, Zayed ME, Alharbi SA, Arfuso F, Kumar AP, Ahn KS, Sethi G.

Cancer Lett. 2018 Apr 28;420:259. doi: 10.1016/j.canlet.2018.01.003. Epub 2018 Jan 17. No abstract available.

PMID:
29338890
50.

Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironment.

Moraes LA, Kar S, Foo SL, Gu T, Toh YQ, Ampomah PB, Sachaphibulkij K, Yap G, Zharkova O, Lukman HM, Fairhurst AM, Kumar AP, Lim LHK.

Sci Rep. 2017 Dec 20;7(1):17925. doi: 10.1038/s41598-017-17622-5.

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