Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 43

1.

Loss of autophagy impairs physiological steatosis by accumulation of NCoR1.

Takahashi SS, Sou YS, Saito T, Kuma A, Yabe T, Sugiura Y, Lee HC, Suematsu M, Yokomizo T, Koike M, Terai S, Mizushima N, Waguri S, Komatsu M.

Life Sci Alliance. 2019 Dec 26;3(1). pii: e201900513. doi: 10.26508/lsa.201900513. Print 2020 Jan.

2.

A pilot model of patient education and counselling for drug-resistant tuberculosis in Daru, Papua New Guinea.

Adepoyibi T, Keam T, Kuma A, Haihuie T, Hapolo M, Islam S, Akumu B, Chani K, Morris L, Taune M.

Public Health Action. 2019 Sep 21;9(Suppl 1):S80-S82. doi: 10.5588/pha.18.0096.

3.

Autophagy regulates lipid metabolism through selective turnover of NCoR1.

Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, Okuda S, Lee HC, Ikeda K, Kanegae Y, Saito I, Auwerx J, Motohashi H, Suematsu M, Soga T, Yokomizo T, Waguri S, Mizushima N, Komatsu M.

Nat Commun. 2019 Apr 5;10(1):1567. doi: 10.1038/s41467-019-08829-3.

4.

Relationship between abdominal adiposity and incident chronic kidney disease in young- to middle-aged working men: a retrospective cohort study.

Kuma A, Uchino B, Ochiai Y, Kawashima M, Enta K, Tamura M, Otsuji Y, Kato A.

Clin Exp Nephrol. 2019 Jan;23(1):76-84. doi: 10.1007/s10157-018-1606-y. Epub 2018 Jun 27.

PMID:
29951724
5.

Autophagy-monitoring and autophagy-deficient mice.

Kuma A, Komatsu M, Mizushima N.

Autophagy. 2017 Oct 3;13(10):1619-1628. doi: 10.1080/15548627.2017.1343770. Epub 2017 Aug 18. Review.

6.

Impact of low-density lipoprotein cholesterol on decline in estimated glomerular filtration rate in apparently healthy young to middle-aged working men.

Kuma A, Uchino B, Ochiai Y, Kawashima M, Enta K, Tamura M, Otsuji Y, Kato A.

Clin Exp Nephrol. 2018 Feb;22(1):15-27. doi: 10.1007/s10157-017-1407-8. Epub 2017 Apr 6.

PMID:
28386655
7.

Transgenic rescue of Atg5-null mice from neonatal lethality with neuron-specific expression of ATG5: Systemic analysis of adult Atg5-deficient mice.

Yoshii SR, Kuma A, Mizushima N.

Autophagy. 2017 Apr 3;13(4):763-764. doi: 10.1080/15548627.2017.1280221. Epub 2017 Feb 22.

8.

Corrigendum to "High glucose concentration-induced expression of pentraxin-3 in a rat model of continuous peritoneal dialysis".

Ishimatsu N, Miyamoto T, Ueno H, Hasegawa E, Kuma A, Fujimoto Y, Bando K, Nakamata J, Furuno Y, Serino R, Baba R, Morimoto H, Doi Y, Tamura M, Otsuji Y.

Histol Histopathol. 2017 Jun;32(6):649. doi: 10.14670/HH-11-865. Epub 2016 Dec 29.

PMID:
28032888
9.

Monocarboxylate Transporter-1 Mediates the Protective Effects of Neutral-pH Bicarbonate/Lactate-Buffered Peritoneal Dialysis Fluid on Cell Viability and Apoptosis.

Kuma A, Tamura M, Ishimatsu N, Harada Y, Izumi H, Miyamoto T, Furuno Y, Nakano Y, Serino R, Otsuji Y.

Ther Apher Dial. 2017 Feb;21(1):62-70. doi: 10.1111/1744-9987.12476. Epub 2016 Dec 12.

PMID:
27957817
10.

Systemic Analysis of Atg5-Null Mice Rescued from Neonatal Lethality by Transgenic ATG5 Expression in Neurons.

Yoshii SR, Kuma A, Akashi T, Hara T, Yamamoto A, Kurikawa Y, Itakura E, Tsukamoto S, Shitara H, Eishi Y, Mizushima N.

Dev Cell. 2016 Oct 10;39(1):116-130. doi: 10.1016/j.devcel.2016.09.001. Epub 2016 Sep 29.

11.

High glucose concentration-induced expression of pentraxin-3 in a rat model of continuous peritoneal dialysis.

Ishimatsu N, Miyamoto T, Ueno H, Hasegawa E, Kuma A, Fujimoto Y, Bando K, Nakamata J, Furuno Y, Serino R, Baba R, Morimoto H, Doi Y, Tamura M, Otsuji Y.

Histol Histopathol. 2016 Nov;31(11):1251-8. doi: 10.14670/HH-11-756. Epub 2016 Mar 15. Erratum in: Histol Histopathol. 2017 Jun;32(6):649.

PMID:
26975967
12.

[Mechanism of and Therapy for Kidney Fibrosis].

Kuma A, Tamura M, Otsuji Y.

J UOEH. 2016 Mar 1;38(1):25-34. doi: 10.7888/juoeh.38.25. Review. Japanese.

13.

Erratum to: Strong expression of polypeptide N-acetylgalactosaminyltransferase 3 independently predicts shortened disease-free survival in patients with early stage oral squamous cell carcinoma.

Harada Y, Izumi H, Noguchi H, Kuma A, Kawatsu Y, Kimura T, Kitada S, Uramoto H, Wang KY, Sasaguri Y, Hijioka H, Miyawaki A, Oya R, Nakayama T, Kohno K, Yamada S.

Tumour Biol. 2015 Dec;36(12):10003-4. doi: 10.1007/s13277-015-4211-7. No abstract available.

14.

Mitochondrial Transcription Factor A and Mitochondrial Genome as Molecular Targets for Cisplatin-Based Cancer Chemotherapy.

Kohno K, Wang KY, Takahashi M, Kurita T, Yoshida Y, Hirakawa M, Harada Y, Kuma A, Izumi H, Matsumoto S.

Int J Mol Sci. 2015 Aug 20;16(8):19836-50. doi: 10.3390/ijms160819836. Review.

15.

Strong expression of polypeptide N-acetylgalactosaminyltransferase 3 independently predicts shortened disease-free survival in patients with early stage oral squamous cell carcinoma.

Harada Y, Izumi H, Noguchi H, Kuma A, Kawatsu Y, Kimura T, Kitada S, Uramoto H, Wang KY, Sasaguri Y, Hijioka H, Miyawaki A, Oya R, Nakayama T, Kohno K, Yamada S.

Tumour Biol. 2016 Jan;37(1):1357-68. doi: 10.1007/s13277-015-3928-7. Epub 2015 Aug 22. Erratum in: Tumour Biol. 2015 Dec;36(12):10003-4.

16.

A novel UMOD gene mutation associated with uromodulin-associated kidney disease in a young woman with moderate kidney dysfunction.

Kuma A, Tamura M, Ishimatsu N, Miyamoto T, Serino R, Ishimori S, Morisada N, Iijima K, Yamada S, Takeuchi M, Abe H, Otsuji Y.

Intern Med. 2015;54(6):631-5. doi: 10.2169/internalmedicine.54.3151. Epub 2015 Jan 15.

17.

Role of WNT10A-expressing kidney fibroblasts in acute interstitial nephritis.

Kuma A, Yamada S, Wang KY, Kitamura N, Yamaguchi T, Iwai Y, Izumi H, Tamura M, Otsuji Y, Kohno K.

PLoS One. 2014 Jul 23;9(7):e103240. doi: 10.1371/journal.pone.0103240. eCollection 2014.

18.

Cycloheximide inhibits starvation-induced autophagy through mTORC1 activation.

Watanabe-Asano T, Kuma A, Mizushima N.

Biochem Biophys Res Commun. 2014 Mar 7;445(2):334-9. doi: 10.1016/j.bbrc.2014.01.180. Epub 2014 Feb 10.

PMID:
24525133
19.

Hypersensitivity to aurora kinase inhibitors in cells resistant against platinum- containing anticancer agents.

Akiyama M, Izumi H, Wang KY, Yamaguchi T, Kuma A, Kitamura N, Harada Y, Oya R, Yamaguchi K, Iwai Y, Kohno K.

Anticancer Agents Med Chem. 2014;14(7):1042-50.

PMID:
24521151
20.

Polypeptide N-acetylgalactosaminyl transferase 3 independently predicts high-grade tumours and poor prognosis in patients with renal cell carcinomas.

Kitada S, Yamada S, Kuma A, Ouchi S, Tasaki T, Nabeshima A, Noguchi H, Wang KY, Shimajiri S, Nakano R, Izumi H, Kohno K, Matsumoto T, Sasaguri Y.

Br J Cancer. 2013 Jul 23;109(2):472-81. doi: 10.1038/bjc.2013.331. Epub 2013 Jun 25.

21.

Differential contribution of insulin and amino acids to the mTORC1-autophagy pathway in the liver and muscle.

Naito T, Kuma A, Mizushima N.

J Biol Chem. 2013 Jul 19;288(29):21074-81. doi: 10.1074/jbc.M113.456228. Epub 2013 Jun 6.

22.

No ATG is an island--the connection of autophagy with diverse pathways and functions.

Komatsu M, Kuma A, Okamoto K.

EMBO Rep. 2013 Mar 1;14(3):219-21. doi: 10.1038/embor.2013.14. Epub 2012 Feb 15. No abstract available.

23.

Proteasome-dependent activation of mammalian target of rapamycin complex 1 (mTORC1) is essential for autophagy suppression and muscle remodeling following denervation.

Quy PN, Kuma A, Pierre P, Mizushima N.

J Biol Chem. 2013 Jan 11;288(2):1125-34. doi: 10.1074/jbc.M112.399949. Epub 2012 Dec 3. Erratum in: J Biol Chem. 2013 May 10;288(19):13639.

24.

[Physiological role of autophagy in metabolism and its regulation mechanism].

Watanabe T, Kuma A, Mizushima N.

Nihon Rinsho. 2011 Jan;69 Suppl 1:775-81. Review. Japanese. No abstract available.

PMID:
21766696
25.

Forced Expression of ZNF143 Restrains Cancer Cell Growth.

Izumi H, Yasuniwa Y, Akiyama M, Yamaguchi T, Kuma A, Kitamura N, Kohno K.

Cancers (Basel). 2011 Oct 19;3(4):3909-20. doi: 10.3390/cancers3043909.

26.

Physiological role of autophagy as an intracellular recycling system: with an emphasis on nutrient metabolism.

Kuma A, Mizushima N.

Semin Cell Dev Biol. 2010 Sep;21(7):683-90. doi: 10.1016/j.semcdb.2010.03.002. Epub 2010 Mar 17.

PMID:
20223289
27.

[Autophagy in embryogenesis and cell differentiation].

Mizushima N, Tsukamoto S, Kuma A.

Tanpakushitsu Kakusan Koso. 2008 Dec;53(16 Suppl):2170-4. Review. Japanese. No abstract available.

PMID:
21166264
28.

The role of autophagy during the oocyte-to-embryo transition.

Tsukamoto S, Kuma A, Mizushima N.

Autophagy. 2008 Nov;4(8):1076-8. Epub 2008 Nov 22.

PMID:
18849666
29.

Autophagy is essential for preimplantation development of mouse embryos.

Tsukamoto S, Kuma A, Murakami M, Kishi C, Yamamoto A, Mizushima N.

Science. 2008 Jul 4;321(5885):117-20. doi: 10.1126/science.1154822.

30.

Autophagosomes in GFP-LC3 Transgenic Mice.

Mizushima N, Kuma A.

Methods Mol Biol. 2008;445:119-24. doi: 10.1007/978-1-59745-157-4_7.

PMID:
18425446
31.

Chromosomal mapping of the GFP-LC3 transgene in GFP-LC3 mice.

Kuma A, Mizushima N.

Autophagy. 2008 Jan;4(1):61-2. Epub 2007 Aug 7.

PMID:
17786029
32.
33.

[Autophagy in differentiation and development].

Kuma A, Mizushima N.

Tanpakushitsu Kakusan Koso. 2006 Aug;51(10 Suppl):1503-6. Japanese. No abstract available.

PMID:
16922428
34.

Organelle degradation during the lens and erythroid differentiation is independent of autophagy.

Matsui M, Yamamoto A, Kuma A, Ohsumi Y, Mizushima N.

Biochem Biophys Res Commun. 2006 Jan 13;339(2):485-9. Epub 2005 Nov 15.

PMID:
16300732
35.

Absorption characteristics of model compounds from the small intestinal serosal surface and a comparison with other organ surfaces.

Nishida K, Kuma A, Fumoto S, Nakashima M, Sasaki H, Nakamura J.

J Pharm Pharmacol. 2005 Aug;57(8):1073-7.

PMID:
16102265
36.

Delivery advantage to the unilateral kidney by direct drug application to the kidney surface in rats and pharmacokinetic verification based on a physiological model.

Nishida K, Kamenosono M, Kuma A, Fumoto S, Mukai T, Nakashima M, Sasaki H, Nakamura J.

J Drug Target. 2005 May;13(4):215-23.

PMID:
16051533
37.

The role of autophagy during the early neonatal starvation period.

Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, Yoshimori T, Ohsumi Y, Tokuhisa T, Mizushima N.

Nature. 2004 Dec 23;432(7020):1032-6. Epub 2004 Nov 3.

PMID:
15525940
38.

Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes.

Simonsen A, Birkeland HC, Gillooly DJ, Mizushima N, Kuma A, Yoshimori T, Slagsvold T, Brech A, Stenmark H.

J Cell Sci. 2004 Aug 15;117(Pt 18):4239-51. Epub 2004 Aug 3.

39.

Binding of 14-3-3beta but not 14-3-3sigma controls the cytoplasmic localization of CDC25B: binding site preferences of 14-3-3 subtypes and the subcellular localization of CDC25B.

Uchida S, Kuma A, Ohtsubo M, Shimura M, Hirata M, Nakagama H, Matsunaga T, Ishizaka Y, Yamashita K.

J Cell Sci. 2004 Jun 15;117(Pt 14):3011-20. Epub 2004 Jun 1.

40.

Absorption of phenolsulfonphthalein as a model across the mesenteric surface in rats to determine the drug absorption route after intraperitoneal administration.

Nishida K, Nose S, Kuma A, Mukai T, Nakashima M, Sasaki H, Nakamura J.

J Pharm Pharmacol. 2004 May;56(5):683-7.

PMID:
15142348
41.

Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate.

Mizushima N, Kuma A, Kobayashi Y, Yamamoto A, Matsubae M, Takao T, Natsume T, Ohsumi Y, Yoshimori T.

J Cell Sci. 2003 May 1;116(Pt 9):1679-88.

42.

Absorption characteristics of model compounds with different molecular weights from the serosal caecal surface in rats.

Nishida K, Nose S, Kuma A, Mukai T, Kawakami S, Nakashima M, Sasaki H, Sakaeda T, Nakamura J.

J Pharm Pharmacol. 2002 Jul;54(7):1005-9.

PMID:
12162704
43.

Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast.

Kuma A, Mizushima N, Ishihara N, Ohsumi Y.

J Biol Chem. 2002 May 24;277(21):18619-25. Epub 2002 Mar 15.

Supplemental Content

Support Center