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Items: 14

1.

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.

Öhlund D, Handly-Santana A, Biffi G, Elyada E, Almeida AS, Ponz-Sarvise M, Corbo V, Oni TE, Hearn SA, Lee EJ, Chio II, Hwang CI, Tiriac H, Baker LA, Engle DD, Feig C, Kultti A, Egeblad M, Fearon DT, Crawford JM, Clevers H, Park Y, Tuveson DA.

J Exp Med. 2017 Mar 6;214(3):579-596. doi: 10.1084/jem.20162024. Epub 2017 Feb 23.

2.

Accumulation of extracellular hyaluronan by hyaluronan synthase 3 promotes tumor growth and modulates the pancreatic cancer microenvironment.

Kultti A, Zhao C, Singha NC, Zimmerman S, Osgood RJ, Symons R, Jiang P, Li X, Thompson CB, Infante JR, Jacobetz MA, Tuveson DA, Frost GI, Shepard HM, Huang Z.

Biomed Res Int. 2014;2014:817613. doi: 10.1155/2014/817613. Epub 2014 Jul 24.

3.

Recombinant human hyaluronidase PH20 does not stimulate an acute inflammatory response and inhibits lipopolysaccharide-induced neutrophil recruitment in the air pouch model of inflammation.

Huang Z, Zhao C, Chen Y, Cowell JA, Wei G, Kultti A, Huang L, Thompson CB, Rosengren S, Frost GI, Shepard HM.

J Immunol. 2014 Jun 1;192(11):5285-95. doi: 10.4049/jimmunol.1303060. Epub 2014 Apr 28.

4.

Plasma hyaluronan and hemorheology in patients with septic shock: a clinical and experimental study.

Sallisalmi M, Tenhunen J, Kultti A, Tammi M, Pettilä V.

Clin Hemorheol Microcirc. 2014;56(2):133-44. doi: 10.3233/CH-131677.

PMID:
23380965
5.

Synthesis and fragmentation of hyaluronan in renal ischaemia.

Declèves AE, Caron N, Voisin V, Legrand A, Bouby N, Kultti A, Tammi MI, Flamion B.

Nephrol Dial Transplant. 2012 Oct;27(10):3771-81. doi: 10.1093/ndt/gfs098. Epub 2012 Apr 23.

PMID:
22529164
6.

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer.

Jacobetz MA, Chan DS, Neesse A, Bapiro TE, Cook N, Frese KK, Feig C, Nakagawa T, Caldwell ME, Zecchini HI, Lolkema MP, Jiang P, Kultti A, Thompson CB, Maneval DC, Jodrell DI, Frost GI, Shepard HM, Skepper JN, Tuveson DA.

Gut. 2013 Jan;62(1):112-20. doi: 10.1136/gutjnl-2012-302529. Epub 2012 Mar 30.

7.

Therapeutic targeting of hyaluronan in the tumor stroma.

Kultti A, Li X, Jiang P, Thompson CB, Frost GI, Shepard HM.

Cancers (Basel). 2012 Sep 6;4(3):873-903. doi: 10.3390/cancers4030873.

8.

Methyl-beta-cyclodextrin suppresses hyaluronan synthesis by down-regulation of hyaluronan synthase 2 through inhibition of Akt.

Kultti A, Kärnä R, Rilla K, Nurminen P, Koli E, Makkonen KM, Si J, Tammi MI, Tammi RH.

J Biol Chem. 2010 Jul 23;285(30):22901-10. doi: 10.1074/jbc.M109.088435. Epub 2010 May 25.

9.

4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3.

Kultti A, Pasonen-Seppänen S, Jauhiainen M, Rilla KJ, Kärnä R, Pyöriä E, Tammi RH, Tammi MI.

Exp Cell Res. 2009 Jul 1;315(11):1914-23. doi: 10.1016/j.yexcr.2009.03.002. Epub 2009 Mar 13.

PMID:
19285976
10.

Pericellular hyaluronan coat visualized in live cells with a fluorescent probe is scaffolded by plasma membrane protrusions.

Rilla K, Tiihonen R, Kultti A, Tammi M, Tammi R.

J Histochem Cytochem. 2008 Oct;56(10):901-10. doi: 10.1369/jhc.2008.951665. Epub 2008 Jun 23.

11.

Hyaluronan in human tumors: pathobiological and prognostic messages from cell-associated and stromal hyaluronan.

Tammi RH, Kultti A, Kosma VM, Pirinen R, Auvinen P, Tammi MI.

Semin Cancer Biol. 2008 Aug;18(4):288-95. doi: 10.1016/j.semcancer.2008.03.005. Epub 2008 Mar 26. Review.

PMID:
18468453
12.

All-trans retinoic acid-induced hyaluronan production and hyperplasia are partly mediated by EGFR signaling in epidermal keratinocytes.

Pasonen-Seppänen SM, Maytin EV, Törrönen KJ, Hyttinen JM, Hascall VC, MacCallum DK, Kultti AH, Jokela TA, Tammi MI, Tammi RH.

J Invest Dermatol. 2008 Apr;128(4):797-807. Epub 2007 Oct 18.

13.

Hyaluronan synthesis induces microvillus-like cell surface protrusions.

Kultti A, Rilla K, Tiihonen R, Spicer AP, Tammi RH, Tammi MI.

J Biol Chem. 2006 Jun 9;281(23):15821-8. Epub 2006 Apr 4.

14.

Elevated hyaluronan concentration without hyaluronidase activation in malignant epithelial ovarian tumors.

Hiltunen EL, Anttila M, Kultti A, Ropponen K, Penttinen J, Yliskoski M, Kuronen AT, Juhola M, Tammi R, Tammi M, Kosma VM.

Cancer Res. 2002 Nov 15;62(22):6410-3.

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