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Items: 4


Hydrophobic gasket mutation produces gating pore currents in closed human voltage-gated proton channels.

Banh R, Cherny VV, Morgan D, Musset B, Thomas S, Kulleperuma K, Smith SME, Pomès R, DeCoursey TE.

Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):18951-18961. doi: 10.1073/pnas.1905462116. Epub 2019 Aug 28.


Orkambi® and amplifier co-therapy improves function from a rare CFTR mutation in gene-edited cells and patient tissue.

Molinski SV, Ahmadi S, Ip W, Ouyang H, Villella A, Miller JP, Lee PS, Kulleperuma K, Du K, Di Paola M, Eckford PD, Laselva O, Huan LJ, Wellhauser L, Li E, Ray PN, Pomès R, Moraes TJ, Gonska T, Ratjen F, Bear CE.

EMBO Mol Med. 2017 Sep;9(9):1224-1243. doi: 10.15252/emmm.201607137.


Peregrination of the selectivity filter delineates the pore of the human voltage-gated proton channel hHV1.

Morgan D, Musset B, Kulleperuma K, Smith SM, Rajan S, Cherny VV, Pomès R, DeCoursey TE.

J Gen Physiol. 2013 Dec;142(6):625-40. doi: 10.1085/jgp.201311045. Epub 2013 Nov 11.


Construction and validation of a homology model of the human voltage-gated proton channel hHV1.

Kulleperuma K, Smith SM, Morgan D, Musset B, Holyoake J, Chakrabarti N, Cherny VV, DeCoursey TE, Pomès R.

J Gen Physiol. 2013 Apr;141(4):445-65. doi: 10.1085/jgp.201210856.

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