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Items: 32

1.

Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes.

Harms MJ, Li Q, Lee S, Zhang C, Kull B, Hallen S, Thorell A, Alexandersson I, Hagberg CE, Peng XR, Mardinoglu A, Spalding KL, Boucher J.

Cell Rep. 2019 Apr 2;27(1):213-225.e5. doi: 10.1016/j.celrep.2019.03.026.

2.

Human target validation of phosphoinositide 3-kinase (PI3K)β: effects on platelets and insulin sensitivity, using AZD6482 a novel PI3Kβ inhibitor.

Nylander S, Kull B, Björkman JA, Ulvinge JC, Oakes N, Emanuelsson BM, Andersson M, Skärby T, Inghardt T, Fjellström O, Gustafsson D.

J Thromb Haemost. 2012 Oct;10(10):2127-36. doi: 10.1111/j.1538-7836.2012.04898.x.

3.

Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors.

Wahlberg E, Karlberg T, Kouznetsova E, Markova N, Macchiarulo A, Thorsell AG, Pol E, Frostell Å, Ekblad T, Öncü D, Kull B, Robertson GM, Pellicciari R, Schüler H, Weigelt J.

Nat Biotechnol. 2012 Feb 19;30(3):283-8. doi: 10.1038/nbt.2121.

PMID:
22343925
4.

A facilitated approach to evaluate the inhibitor mode and potency of compounds targeting microsomal prostaglandin e synthase-1.

Spahiu L, Stenberg P, Larsson C, Wannberg J, Alterman M, Kull B, Nekhotiaeva N, Morgenstern R.

Assay Drug Dev Technol. 2011 Oct;9(5):487-95. doi: 10.1089/adt.2010.0350. Epub 2011 May 11.

PMID:
21561373
5.

Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats.

Bengtsson C, Blaho S, Saitton DB, Brickmann K, Broddefalk J, Davidsson O, Drmota T, Folmer R, Hallberg K, Hallén S, Hovland R, Isin E, Johannesson P, Kull B, Larsson LO, Löfgren L, Nilsson KE, Noeske T, Oakes N, Plowright AT, Schnecke V, Ståhlberg P, Sörme P, Wan H, Wellner E, Oster L.

Bioorg Med Chem. 2011 May 15;19(10):3039-53. doi: 10.1016/j.bmc.2011.04.014. Epub 2011 Apr 13.

PMID:
21515056
6.

Discovery of novel class 1 phosphatidylinositide 3-kinases (PI3K) fragment inhibitors through structure-based virtual screening.

Giordanetto F, Kull B, Dellsén A.

Bioorg Med Chem Lett. 2011 Jan 15;21(2):829-35. doi: 10.1016/j.bmcl.2010.11.087. Epub 2010 Nov 24.

PMID:
21169017
7.

Cell-based multiwell assays for the detection of substrate accumulation and oxidation.

Wensaas AJ, Rustan AC, Lövstedt K, Kull B, Wikström S, Drevon CA, Hallén S.

J Lipid Res. 2007 Apr;48(4):961-7. Epub 2007 Jan 9.

8.

Evidence against adenosine analogues being agonists at the growth hormone secretagogue receptor.

Johansson S, Fredholm BB, Hjort C, Morein T, Kull B, Hu PS.

Biochem Pharmacol. 2005 Aug 15;70(4):598-605.

PMID:
15979585
9.

Human neuropeptide Y signal peptide gain-of-function polymorphism is associated with increased body mass index: possible mode of function.

Ding B, Kull B, Liu Z, Mottagui-Tabar S, Thonberg H, Gu HF, Brookes AJ, Grundemar L, Karlsson C, Hamsten A, Arner P, Ostenson CG, Efendic S, Monné M, von Heijne G, Eriksson P, Wahlestedt C.

Regul Pept. 2005 Apr 15;127(1-3):45-53.

PMID:
15680469
10.

Dihydrexidine--the first full dopamine D1 receptor agonist.

Salmi P, Isacson R, Kull B.

CNS Drug Rev. 2004 Fall;10(3):230-42. Review.

12.

Lack of efficacy of 'naked' small interfering RNA applied directly to rat brain.

Isacson R, Kull B, Salmi P, Wahlestedt C.

Acta Physiol Scand. 2003 Oct;179(2):173-7.

PMID:
14510781
13.

Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition.

Lopes LV, Cunha RA, Kull B, Fredholm BB, Ribeiro JA.

Neuroscience. 2002;112(2):319-29.

PMID:
12044450
14.

Anoxia redistributes adenosine A(2A) receptors in PC12 cells and increases receptor-mediated formation of cAMP.

Arslan G, Kull B, Fredholm BB.

Naunyn Schmiedebergs Arch Pharmacol. 2002 Feb;365(2):150-7. Epub 2001 Aug 7.

PMID:
11819033
15.

Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells.

Fredholm BB, Irenius E, Kull B, Schulte G.

Biochem Pharmacol. 2001 Feb 15;61(4):443-8.

PMID:
11226378
16.

Manipulation of salicylate content in Arabidopsis thaliana by the expression of an engineered bacterial salicylate synthase.

Mauch F, Mauch-Mani B, Gaille C, Kull B, Haas D, Reimmann C.

Plant J. 2001 Jan;25(1):67-77.

17.

Structure and function of adenosine receptors and their genes.

Fredholm BB, Arslan G, Halldner L, Kull B, Schulte G, Wasserman W.

Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362(4-5):364-74. Review.

PMID:
11111830
18.

Adenosine A(2A) receptors are colocalized with and activate g(olf) in rat striatum.

Kull B, Svenningsson P, Fredholm BB.

Mol Pharmacol. 2000 Oct;58(4):771-7.

PMID:
10999947
19.

GTP differentially affects antagonist radioligand binding to adenosine A(1) and A(2A) receptors in human brain.

Kull B, Svenningsson P, Hall H, Fredholm BB.

Neuropharmacology. 2000 Sep;39(12):2374-80.

PMID:
10974321
20.

P2Y receptors contribute to ATP-induced increases in intracellular calcium in differentiated but not undifferentiated PC12 cells.

Arslan G, Filipeanu CM, Irenius E, Kull B, Clementi E, Allgaier C, Erlinge D, Fredholm BB.

Neuropharmacology. 2000 Jan 28;39(3):482-96.

PMID:
10698014
21.

Reciprocal interactions between adenosine A2A and dopamine D2 receptors in Chinese hamster ovary cells co-transfected with the two receptors.

Kull B, Ferré S, Arslan G, Svenningsson P, Fuxe K, Owman C, Fredholm BB.

Biochem Pharmacol. 1999 Sep 15;58(6):1035-45.

PMID:
10509756
22.

Signaling via A2A adenosine receptor in four PC12 cell clones.

Arslan G, Kull B, Fredholm BB.

Naunyn Schmiedebergs Arch Pharmacol. 1999 Jan;359(1):28-32.

PMID:
9933147
23.

Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.

Kull B, Arslan G, Nilsson C, Owman C, Lorenzen A, Schwabe U, Fredholm BB.

Biochem Pharmacol. 1999 Jan 1;57(1):65-75.

PMID:
9920286
24.

Localization of adenosine receptor messenger RNAs in the rat eye.

Kvanta A, Seregard S, Sejersen S, Kull B, Fredholm BB.

Exp Eye Res. 1997 Nov;65(5):595-602.

PMID:
9367639
25.

Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.

Klotz KN, Hessling J, Hegler J, Owman C, Kull B, Fredholm BB, Lohse MJ.

Naunyn Schmiedebergs Arch Pharmacol. 1998 Jan;357(1):1-9.

PMID:
9459566
26.

Cellular expression of adenosine A2A receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas.

Svenningsson P, Le Moine C, Kull B, Sunahara R, Bloch B, Fredholm BB.

Neuroscience. 1997 Oct;80(4):1171-85.

PMID:
9284069
27.

Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261.

Dionisotti S, Ongini E, Zocchi C, Kull B, Arslan G, Fredholm BB.

Br J Pharmacol. 1997 Jun;121(3):353-60.

28.

In vivo expression of a full-length cDNA copy of potato leafroll virus (PLRV) in protoplasts and transgenic plants.

Prüfer D, Schmitz J, Tacke E, Kull B, Rohde W.

Mol Gen Genet. 1997 Feb 20;253(5):609-14.

PMID:
9065694
29.

Adenosine A2A receptors modulate the binding characteristics of dopamine D2 receptors in stably cotransfected fibroblast cells.

Dasgupta S, Ferré S, Kull B, Hedlund PB, Finnman UB, Ahlberg S, Arenas E, Fredholm BB, Fuxe K.

Eur J Pharmacol. 1996 Dec 5;316(2-3):325-31.

PMID:
8982704
30.

P2x purinoceptor is not important in thymocyte apoptosis.

Jiang S, Kull B, Fredholm BB, Orrenius S.

Immunol Lett. 1996 Mar;49(3):197-201.

PMID:
8739317
31.

Automated procedure for measuring TBARS for in vitro comparison of the effect of antioxidants on tissues.

Svensson L, Börjesson I, Kull B, Sjöquist PO.

Scand J Clin Lab Invest. 1993 Feb;53(1):83-5.

PMID:
8451604
32.

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