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Items: 1 to 50 of 221

1.

First Complete Genome Sequence of Currently Circulating Infectious Bronchitis Virus Strain DMV/1639 of the GI-17 Lineage.

Goraichuk IV, Kulkarni AB, Williams-Coplin D, Suarez DL, Afonso CL.

Microbiol Resour Announc. 2019 Aug 22;8(34). pii: e00840-19. doi: 10.1128/MRA.00840-19.

2.

Blockade of TIGIT/CD155 Signaling Reverses T-cell Exhaustion and Enhances Antitumor Capability in Head and Neck Squamous Cell Carcinoma.

Wu L, Mao L, Liu JF, Chen L, Yu GT, Yang LL, Wu H, Bu LL, Kulkarni AB, Zhang WF, Sun ZJ.

Cancer Immunol Res. 2019 Aug 6. doi: 10.1158/2326-6066.CIR-18-0725. [Epub ahead of print]

PMID:
31387897
3.

Overexpression of the Cdk5 inhibitory peptide in motor neurons rescue of amyotrophic lateral sclerosis phenotype in a mouse model.

Binukumar BK, Skuntz S, Prochazkova M, Kesavapany S, Amin ND, Shukla V, Grant P, Kulkarni AB, Pant HC.

Hum Mol Genet. 2019 Jun 12. pii: ddz118. doi: 10.1093/hmg/ddz118. [Epub ahead of print]

PMID:
31189016
4.

Targeted TNF-α Overexpression Drives Salivary Gland Inflammation.

Limaye A, Hall BE, Zhang L, Cho A, Prochazkova M, Zheng C, Walker M, Adewusi F, Burbelo PD, Sun ZJ, Ambudkar IS, Dolan JC, Schmidt BL, Kulkarni AB.

J Dent Res. 2019 Jun;98(6):713-719. doi: 10.1177/0022034519837240. Epub 2019 Apr 8.

PMID:
30958728
5.

Correction: Behavioral and synaptic alterations relevant to obsessivecompulsive disorder in mice with increased EAAT3 expression.

Delgado-Acevedo C, Estay SF, Radke AK, Sengupta A, Escobar AP, Henríquez-Belmar F, Reyes CA, Haro-Acuña V, Utreras E, Sotomayor-Zárate R, Cho A, Wendland JR, Kulkarni AB, Holmes A, Murphy DL, Chávez AE, Moya PR.

Neuropsychopharmacology. 2019 May;44(6):1177. doi: 10.1038/s41386-019-0331-x.

6.

Behavioral and synaptic alterations relevant to obsessive-compulsive disorder in mice with increased EAAT3 expression.

Delgado-Acevedo C, Estay SF, Radke AK, Sengupta A, Escobar AP, Henríquez-Belmar F, Reyes CA, Haro-Acuña V, Utreras E, Sotomayor-Zárate R, Cho A, Wendland JR, Kulkarni AB, Holmes A, Murphy DL, Chávez AE, Moya PR.

Neuropsychopharmacology. 2019 May;44(6):1163-1173. doi: 10.1038/s41386-018-0302-7. Epub 2018 Dec 26. Erratum in: Neuropsychopharmacology. 2019 Feb 21;:.

PMID:
30622300
7.

Bi-allelic TMEM94 Truncating Variants Are Associated with Neurodevelopmental Delay, Congenital Heart Defects, and Distinct Facial Dysmorphism.

Stephen J, Maddirevula S, Nampoothiri S, Burke JD, Herzog M, Shukla A, Steindl K, Eskin A, Patil SJ, Joset P, Lee H, Garrett LJ, Yokoyama T, Balanda N, Bodine SP, Tolman NJ, Zerfas PM, Zheng A, Ramantani G, Girisha KM, Rivas C, Suresh PV, Elkahloun A, Alsaif HS, Wakil SM, Mahmoud L, Ali R, Prochazkova M; Undiagnosed Diseases Network members, Kulkarni AB, Ben-Omran T, Colak D, Morris HD, Rauch A, Martinez-Agosto JA, Nelson SF, Alkuraya FS, Gahl WA, Malicdan MCV.

Am J Hum Genet. 2018 Dec 6;103(6):948-967. doi: 10.1016/j.ajhg.2018.11.001.

8.

The expression of PD-1 and LAG-3 in periapical lesions.

Wang HS, Yang FH, Li Y, Pei F, Kulkarni AB, Chen Z, Zhang L.

Am J Transl Res. 2018 Aug 15;10(8):2677-2684. eCollection 2018.

9.

Genome Editing in Mice Using CRISPR/Cas9 Technology.

Hall B, Cho A, Limaye A, Cho K, Khillan J, Kulkarni AB.

Curr Protoc Cell Biol. 2018 Dec;81(1):e57. doi: 10.1002/cpcb.57. Epub 2018 Sep 4.

PMID:
30178917
10.

TGF-β receptor 1 regulates progenitors that promote browning of white fat.

Wankhade UD, Lee JH, Dagur PK, Yadav H, Shen M, Chen W, Kulkarni AB, McCoy JP, Finkel T, Cypess AM, Rane SG.

Mol Metab. 2018 Oct;16:160-171. doi: 10.1016/j.molmet.2018.07.008. Epub 2018 Jul 27.

11.

Specific blockade CD73 alters the "exhausted" phenotype of T cells in head and neck squamous cell carcinoma.

Deng WW, Li YC, Ma SR, Mao L, Yu GT, Bu LL, Kulkarni AB, Zhang WF, Sun ZJ.

Int J Cancer. 2018 Sep 15;143(6):1494-1504. doi: 10.1002/ijc.31534.

PMID:
29663369
12.

Anti-CD47 treatment enhances anti-tumor T-cell immunity and improves immunosuppressive environment in head and neck squamous cell carcinoma.

Wu L, Yu GT, Deng WW, Mao L, Yang LL, Ma SR, Bu LL, Kulkarni AB, Zhang WF, Zhang L, Sun ZJ.

Oncoimmunology. 2018 Mar 13;7(4):e1397248. doi: 10.1080/2162402X.2017.1397248. eCollection 2018.

13.

Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception.

Hall BE, Prochazkova M, Sapio MR, Minetos P, Kurochkina N, Binukumar BK, Amin ND, Terse A, Joseph J, Raithel SJ, Mannes AJ, Pant HC, Chung MK, Iadarola MJ, Kulkarni AB.

Sci Rep. 2018 Jan 19;8(1):1177. doi: 10.1038/s41598-018-19532-6.

14.

Meeting report: a hard look at the state of enamel research.

Klein OD, Duverger O, Shaw W, Lacruz RS, Joester D, Moradian-Oldak J, Pugach MK, Wright JT, Millar SE, Kulkarni AB, Bartlett JD, Diekwisch TG, DenBesten P, Simmer JP.

Int J Oral Sci. 2017 Nov 22;9(11):e3. doi: 10.1038/ijos.2017.40.

15.

γ-Secretase inhibitor reduces immunosuppressive cells and enhances tumour immunity in head and neck squamous cell carcinoma.

Mao L, Zhao ZL, Yu GT, Wu L, Deng WW, Li YC, Liu JF, Bu LL, Liu B, Kulkarni AB, Zhang WF, Zhang L, Sun ZJ.

Int J Cancer. 2018 Mar 1;142(5):999-1009. doi: 10.1002/ijc.31115. Epub 2017 Nov 2.

16.

Cyclin-dependent kinase 5 modulates the P2X2a receptor channel gating through phosphorylation of C-terminal threonine 372.

Coddou C, Sandoval R, Castro P, Lazcano P, Hevia MJ, Rokic M, Hall B, Terse A, Gonzalez-Billault C, Kulkarni AB, Stojilkovic SS, Utreras E.

Pain. 2017 Nov;158(11):2155-2168. doi: 10.1097/j.pain.0000000000001021.

17.

STAT3 Induces Immunosuppression by Upregulating PD-1/PD-L1 in HNSCC.

Bu LL, Yu GT, Wu L, Mao L, Deng WW, Liu JF, Kulkarni AB, Zhang WF, Zhang L, Sun ZJ.

J Dent Res. 2017 Aug;96(9):1027-1034. doi: 10.1177/0022034517712435. Epub 2017 Jun 12.

PMID:
28605599
18.

Blockade of adenosine A2A receptor enhances CD8+ T cells response and decreases regulatory T cells in head and neck squamous cell carcinoma.

Ma SR, Deng WW, Liu JF, Mao L, Yu GT, Bu LL, Kulkarni AB, Zhang WF, Sun ZJ.

Mol Cancer. 2017 Jun 7;16(1):99. doi: 10.1186/s12943-017-0665-0.

19.

Selective blockade of B7-H3 enhances antitumour immune activity by reducing immature myeloid cells in head and neck squamous cell carcinoma.

Mao L, Fan TF, Wu L, Yu GT, Deng WW, Chen L, Bu LL, Ma SR, Liu B, Bian Y, Kulkarni AB, Zhang WF, Sun ZJ.

J Cell Mol Med. 2017 Sep;21(9):2199-2210. doi: 10.1111/jcmm.13143. Epub 2017 Apr 11.

20.

T-cell immunoglobulin mucin 3 blockade drives an antitumor immune response in head and neck cancer.

Liu JF, Ma SR, Mao L, Bu LL, Yu GT, Li YC, Huang CF, Deng WW, Kulkarni AB, Zhang WF, Sun ZJ.

Mol Oncol. 2017 Feb;11(2):235-247. doi: 10.1002/1878-0261.12029. Epub 2017 Jan 19.

21.

LAG-3 confers poor prognosis and its blockade reshapes antitumor response in head and neck squamous cell carcinoma.

Deng WW, Mao L, Yu GT, Bu LL, Ma SR, Liu B, Gutkind JS, Kulkarni AB, Zhang WF, Sun ZJ.

Oncoimmunology. 2016 Oct 7;5(11):e1239005. doi: 10.1080/2162402X.2016.1239005. eCollection 2016.

22.

Inhibition of SRC family kinases reduces myeloid-derived suppressor cells in head and neck cancer.

Mao L, Deng WW, Yu GT, Bu LL, Liu JF, Ma SR, Wu L, Kulkarni AB, Zhang WF, Sun ZJ.

Int J Cancer. 2017 Mar 1;140(5):1173-1185. doi: 10.1002/ijc.30493. Epub 2016 Dec 2.

23.

Targeting STAT3 signaling reduces immunosuppressive myeloid cells in head and neck squamous cell carcinoma.

Bu LL, Yu GT, Deng WW, Mao L, Liu JF, Ma SR, Fan TF, Hall B, Kulkarni AB, Zhang WF, Sun ZJ.

Oncoimmunology. 2016 Jan 19;5(5):e1130206. doi: 10.1080/2162402X.2015.1130206. eCollection 2016 May.

24.

NOTCH1 inhibition enhances the efficacy of conventional chemotherapeutic agents by targeting head neck cancer stem cell.

Zhao ZL, Zhang L, Huang CF, Ma SR, Bu LL, Liu JF, Yu GT, Liu B, Gutkind JS, Kulkarni AB, Zhang WF, Sun ZJ.

Sci Rep. 2016 Apr 25;6:24704. doi: 10.1038/srep24704.

25.

Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis.

Meijer L, Nelson DJ, Riazanski V, Gabdoulkhakova AG, Hery-Arnaud G, Le Berre R, Loaëc N, Oumata N, Galons H, Nowak E, Gueganton L, Dorothée G, Prochazkova M, Hall B, Kulkarni AB, Gray RD, Rossi AG, Witko-Sarsat V, Norez C, Becq F, Ravel D, Mottier D, Rault G.

J Innate Immun. 2016;8(4):330-49. doi: 10.1159/000444256. Epub 2016 Mar 18. Review.

26.

TRPV1 function is modulated by Cdk5-mediated phosphorylation: insights into the molecular mechanism of nociception.

Jendryke T, Prochazkova M, Hall BE, Nordmann GC, Schladt M, Milenkovic VM, Kulkarni AB, Wetzel CH.

Sci Rep. 2016 Feb 23;6:22007. doi: 10.1038/srep22007.

27.

Targeted overexpression of tumor necrosis factor-α increases cyclin-dependent kinase 5 activity and TRPV1-dependent Ca2+ influx in trigeminal neurons.

Rozas P, Lazcano P, Piña R, Cho A, Terse A, Pertusa M, Madrid R, Gonzalez-Billault C, Kulkarni AB, Utreras E.

Pain. 2016 Jun;157(6):1346-62. doi: 10.1097/j.pain.0000000000000527.

28.

PD-1 blockade attenuates immunosuppressive myeloid cells due to inhibition of CD47/SIRPα axis in HPV negative head and neck squamous cell carcinoma.

Yu GT, Bu LL, Huang CF, Zhang WF, Chen WJ, Gutkind JS, Kulkarni AB, Sun ZJ.

Oncotarget. 2015 Dec 8;6(39):42067-80. doi: 10.18632/oncotarget.5955.

29.

Conditional TNF-α Overexpression in the Tooth and Alveolar Bone Results in Painful Pulpitis and Osteitis.

Hall BE, Zhang L, Sun ZJ, Utreras E, Prochazkova M, Cho A, Terse A, Arany P, Dolan JC, Schmidt BL, Kulkarni AB.

J Dent Res. 2016 Feb;95(2):188-95. doi: 10.1177/0022034515612022. Epub 2015 Oct 26.

30.

Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma.

Zhang L, Zhang W, Wang YF, Liu B, Zhang WF, Zhao YF, Kulkarni AB, Sun ZJ.

Cell Death Dis. 2015 May 28;6:e1771. doi: 10.1038/cddis.2015.139.

31.

Epidermal growth factor receptor inhibition reduces angiogenesis via hypoxia-inducible factor-1α and Notch1 in head neck squamous cell carcinoma.

Wang WM, Zhao ZL, Ma SR, Yu GT, Liu B, Zhang L, Zhang WF, Kulkarni AB, Sun ZJ, Zhao YF.

PLoS One. 2015 Feb 27;10(2):e0119723. doi: 10.1371/journal.pone.0119723. eCollection 2015.

32.

Adhesive and migratory effects of phosphophoryn are modulated by flanking peptides of the integrin binding motif.

Suzuki S, Kobuke S, Haruyama N, Hoshino H, Kulkarni AB, Nishimura F.

PLoS One. 2014 Nov 14;9(11):e112490. doi: 10.1371/journal.pone.0112490. eCollection 2014.

33.

Tracking endogenous amelogenin and ameloblastin in vivo.

Jacques J, Hotton D, De la Dure-Molla M, Petit S, Asselin A, Kulkarni AB, Gibson CW, Brookes SJ, Berdal A, Isaac J.

PLoS One. 2014 Jun 16;9(6):e99626. doi: 10.1371/journal.pone.0099626. eCollection 2014.

34.

Photoactivation of endogenous latent transforming growth factor-β1 directs dental stem cell differentiation for regeneration.

Arany PR, Cho A, Hunt TD, Sidhu G, Shin K, Hahm E, Huang GX, Weaver J, Chen AC, Padwa BL, Hamblin MR, Barcellos-Hoff MH, Kulkarni AB, J Mooney D.

Sci Transl Med. 2014 May 28;6(238):238ra69. doi: 10.1126/scitranslmed.3008234.

35.

Mouse genetic background influences the dental phenotype.

Li Y, Konicki WS, Wright JT, Suggs C, Xue H, Kuehl MA, Kulkarni AB, Gibson CW.

Cells Tissues Organs. 2013;198(6):448-56. doi: 10.1159/000360157. Epub 2014 Apr 8.

36.

Regulation of Sox6 by cyclin dependent kinase 5 in brain.

Rudrabhatla P, Utreras E, Jaffe H, Kulkarni AB.

PLoS One. 2014 Mar 24;9(3):e89310. doi: 10.1371/journal.pone.0089310. eCollection 2014.

37.

Searching for novel Cdk5 substrates in brain by comparative phosphoproteomics of wild type and Cdk5-/- mice.

Contreras-Vallejos E, Utreras E, Bórquez DA, Prochazkova M, Terse A, Jaffe H, Toledo A, Arruti C, Pant HC, Kulkarni AB, González-Billault C.

PLoS One. 2014 Mar 21;9(3):e90363. doi: 10.1371/journal.pone.0090363. eCollection 2014.

38.

Suppression of neuroinflammation in forebrain-specific Cdk5 conditional knockout mice by PPARγ agonist improves neuronal loss and early lethality.

Utreras E, Hamada R, Prochazkova M, Terse A, Takahashi S, Ohshima T, Kulkarni AB.

J Neuroinflammation. 2014 Feb 5;11:28. doi: 10.1186/1742-2094-11-28.

39.

Induction of autophagy-dependent cell death by the survivin suppressant YM155 in salivary adenoid cystic carcinoma.

Wang YF, Zhang W, He KF, Liu B, Zhang L, Zhang WF, Kulkarni AB, Zhao YF, Sun ZJ.

Apoptosis. 2014 Apr;19(4):748-58. doi: 10.1007/s10495-013-0960-1.

40.

Activation of cyclin-dependent kinase 5 mediates orofacial mechanical hyperalgesia.

Prochazkova M, Terse A, Amin ND, Hall B, Utreras E, Pant HC, Kulkarni AB.

Mol Pain. 2013 Dec 21;9:66. doi: 10.1186/1744-8069-9-66.

41.

TGF-ß regulates enamel mineralization and maturation through KLK4 expression.

Cho A, Haruyama N, Hall B, Danton MJ, Zhang L, Arany P, Mooney DJ, Harichane Y, Goldberg M, Gibson CW, Kulkarni AB.

PLoS One. 2013 Nov 20;8(11):e82267. doi: 10.1371/journal.pone.0082267. eCollection 2013.

42.

Inhibition of mTOR reduces anal carcinogenesis in transgenic mouse model.

Sun ZJ, Zhang L, Zhang W, Hall B, Bian Y, Kulkarni AB.

PLoS One. 2013 Oct 4;8(10):e74888. doi: 10.1371/journal.pone.0074888. eCollection 2013.

43.

A symptomatic Fabry disease mouse model generated by inducing globotriaosylceramide synthesis.

Taguchi A, Maruyama H, Nameta M, Yamamoto T, Matsuda J, Kulkarni AB, Yoshioka H, Ishii S.

Biochem J. 2013 Dec 15;456(3):373-83. doi: 10.1042/BJ20130825.

44.

M180 amelogenin processed by MMP20 is sufficient for decussating murine enamel.

Pugach MK, Suggs C, Li Y, Wright JT, Kulkarni AB, Bartlett JD, Gibson CW.

J Dent Res. 2013 Dec;92(12):1118-22. doi: 10.1177/0022034513506444. Epub 2013 Sep 26.

45.

Transforming growth factor-β3 (TGF-β3) knock-in ameliorates inflammation due to TGF-β1 deficiency while promoting glucose tolerance.

Hall BE, Wankhade UD, Konkel JE, Cherukuri K, Nagineni CN, Flanders KC, Arany PR, Chen W, Rane SG, Kulkarni AB.

J Biol Chem. 2013 Nov 1;288(44):32074-92. doi: 10.1074/jbc.M113.480764. Epub 2013 Sep 20.

46.

TGF-β1 sensitizes TRPV1 through Cdk5 signaling in odontoblast-like cells.

Utreras E, Prochazkova M, Terse A, Gross J, Keller J, Iadarola MJ, Kulkarni AB.

Mol Pain. 2013 May 13;9:24. doi: 10.1186/1744-8069-9-24.

47.

PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer.

Herzog A, Bian Y, Vander Broek R, Hall B, Coupar J, Cheng H, Sowers AL, Cook JD, Mitchell JB, Chen Z, Kulkarni AB, Van Waes C.

Clin Cancer Res. 2013 Jul 15;19(14):3808-19. doi: 10.1158/1078-0432.CCR-12-2716. Epub 2013 May 2.

48.

Expression and function of enamel-related gene products in calvarial development.

Atsawasuwan P, Lu X, Ito Y, Chen Y, Gopinathan G, Evans CA, Kulkarni AB, Gibson CW, Luan X, Diekwisch TG.

J Dent Res. 2013 Jul;92(7):622-8. doi: 10.1177/0022034513487906. Epub 2013 Apr 26.

49.

Targeting of interleukin-13 receptor α2 for treatment of head and neck squamous cell carcinoma induced by conditional deletion of TGF-β and PTEN signaling.

Hall B, Nakashima H, Sun ZJ, Sato Y, Bian Y, Husain SR, Puri RK, Kulkarni AB.

J Transl Med. 2013 Feb 19;11:45. doi: 10.1186/1479-5876-11-45.

50.

Cdk5 regulates Rap1 activity.

Utreras E, Henriquez D, Contreras-Vallejos E, Olmos C, Di Genova A, Maass A, Kulkarni AB, Gonzalez-Billault C.

Neurochem Int. 2013 May;62(6):848-53. doi: 10.1016/j.neuint.2013.02.011. Epub 2013 Feb 13.

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