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Items: 24


The Acinetobacter baumannii Mla system and glycerophospholipid transport to the outer membrane.

Kamischke C, Fan J, Bergeron J, Kulasekara HD, Dalebroux ZD, Burrell A, Kollman JM, Miller SI.

Elife. 2019 Jan 14;8. pii: e40171. doi: 10.7554/eLife.40171.


Identification of Small-Molecule Modulators of Diguanylate Cyclase by FRET-Based High-Throughput Screening.

Christen M, Kamischke C, Kulasekara HD, Olivas KC, Kulasekara BR, Christen B, Kline T, Miller SI.

Chembiochem. 2019 Feb 1;20(3):394-407. doi: 10.1002/cbic.201800593. Epub 2018 Dec 27.


Conditional toxicity and synergy drive diversity among antibacterial effectors.

LaCourse KD, Peterson SB, Kulasekara HD, Radey MC, Kim J, Mougous JD.

Nat Microbiol. 2018 Apr;3(4):440-446. doi: 10.1038/s41564-018-0113-y. Epub 2018 Feb 19.


A broadly distributed toxin family mediates contact-dependent antagonism between gram-positive bacteria.

Whitney JC, Peterson SB, Kim J, Pazos M, Verster AJ, Radey MC, Kulasekara HD, Ching MQ, Bullen NP, Bryant D, Goo YA, Surette MG, Borenstein E, Vollmer W, Mougous JD.

Elife. 2017 Jul 11;6. pii: e26938. doi: 10.7554/eLife.26938.


In vivo protein interaction network analysis reveals porin-localized antibiotic inactivation in Acinetobacter baumannii strain AB5075.

Wu X, Chavez JD, Schweppe DK, Zheng C, Weisbrod CR, Eng JK, Murali A, Lee SA, Ramage E, Gallagher LA, Kulasekara HD, Edrozo ME, Kamischke CN, Brittnacher MJ, Miller SI, Singh PK, Manoil C, Bruce JE.

Nat Commun. 2016 Nov 11;7:13414. doi: 10.1038/ncomms13414.


Pyomelanin-producing Pseudomonas aeruginosa selected during chronic infections have a large chromosomal deletion which confers resistance to pyocins.

Hocquet D, Petitjean M, Rohmer L, Valot B, Kulasekara HD, Bedel E, Bertrand X, Plésiat P, Köhler T, Pantel A, Jacobs MA, Hoffman LR, Miller SI.

Environ Microbiol. 2016 Oct;18(10):3482-3493. doi: 10.1111/1462-2920.13336. Epub 2016 Jun 2.


Pseudomonas aeruginosa in vitro phenotypes distinguish cystic fibrosis infection stages and outcomes.

Mayer-Hamblett N, Rosenfeld M, Gibson RL, Ramsey BW, Kulasekara HD, Retsch-Bogart GZ, Morgan W, Wolter DJ, Pope CE, Houston LS, Kulasekara BR, Khan U, Burns JL, Miller SI, Hoffman LR.

Am J Respir Crit Care Med. 2014 Aug 1;190(3):289-97. doi: 10.1164/rccm.201404-0681OC.


Pseudomonas aeruginosa phenotypes associated with eradication failure in children with cystic fibrosis.

Mayer-Hamblett N, Ramsey BW, Kulasekara HD, Wolter DJ, Houston LS, Pope CE, Kulasekara BR, Armbruster CR, Burns JL, Retsch-Bogart G, Rosenfeld M, Gibson RL, Miller SI, Khan U, Hoffman LR.

Clin Infect Dis. 2014 Sep 1;59(5):624-31. doi: 10.1093/cid/ciu385. Epub 2014 May 26.


Transposon mutagenesis.

Kulasekara HD.

Methods Mol Biol. 2014;1149:501-19. doi: 10.1007/978-1-4939-0473-0_39.


c-di-GMP heterogeneity is generated by the chemotaxis machinery to regulate flagellar motility.

Kulasekara BR, Kamischke C, Kulasekara HD, Christen M, Wiggins PA, Miller SI.

Elife. 2013 Dec 17;2:e01402. doi: 10.7554/eLife.01402.


The response threshold of Salmonella PilZ domain proteins is determined by their binding affinities for c-di-GMP.

Pultz IS, Christen M, Kulasekara HD, Kennard A, Kulasekara B, Miller SI.

Mol Microbiol. 2012 Dec;86(6):1424-40. doi: 10.1111/mmi.12066. Epub 2012 Nov 19.


Evidence for induction of integron-based antibiotic resistance by the SOS response in a clinical setting.

Hocquet D, Llanes C, Thouverez M, Kulasekara HD, Bertrand X, Plésiat P, Mazel D, Miller SI.

PLoS Pathog. 2012;8(6):e1002778. doi: 10.1371/journal.ppat.1002778. Epub 2012 Jun 14.


The bacterial second messenger c-di-GMP: mechanisms of signalling.

Mills E, Pultz IS, Kulasekara HD, Miller SI.

Cell Microbiol. 2011 Aug;13(8):1122-9. doi: 10.1111/j.1462-5822.2011.01619.x. Epub 2011 Jun 24. Review.


Asymmetrical distribution of the second messenger c-di-GMP upon bacterial cell division.

Christen M, Kulasekara HD, Christen B, Kulasekara BR, Hoffman LR, Miller SI.

Science. 2010 Jun 4;328(5983):1295-7. doi: 10.1126/science.1188658.


Nutrient availability as a mechanism for selection of antibiotic tolerant Pseudomonas aeruginosa within the CF airway.

Hoffman LR, Richardson AR, Houston LS, Kulasekara HD, Martens-Habbena W, Klausen M, Burns JL, Stahl DA, Hassett DJ, Fang FC, Miller SI.

PLoS Pathog. 2010 Jan 8;6(1):e1000712. doi: 10.1371/journal.ppat.1000712.


Precursor acquisition independent from ion count: how to dive deeper into the proteomics ocean.

Panchaud A, Scherl A, Shaffer SA, von Haller PD, Kulasekara HD, Miller SI, Goodlett DR.

Anal Chem. 2009 Aug 1;81(15):6481-8. doi: 10.1021/ac900888s.


Pseudomonas aeruginosa lasR mutants are associated with cystic fibrosis lung disease progression.

Hoffman LR, Kulasekara HD, Emerson J, Houston LS, Burns JL, Ramsey BW, Miller SI.

J Cyst Fibros. 2009 Jan;8(1):66-70. doi: 10.1016/j.jcf.2008.09.006. Epub 2008 Oct 29.


Genome-specific gas-phase fractionation strategy for improved shotgun proteomic profiling of proteotypic peptides.

Scherl A, Shaffer SA, Taylor GK, Kulasekara HD, Miller SI, Goodlett DR.

Anal Chem. 2008 Feb 15;80(4):1182-91. doi: 10.1021/ac701680f. Epub 2008 Jan 23.


Threonine phosphorylation times bacterial secretion.

Kulasekara HD, Miller SI.

Nat Cell Biol. 2007 Jul;9(7):734-6. No abstract available.


Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients.

D'Argenio DA, Wu M, Hoffman LR, Kulasekara HD, Déziel E, Smith EE, Nguyen H, Ernst RK, Larson Freeman TJ, Spencer DH, Brittnacher M, Hayden HS, Selgrade S, Klausen M, Goodlett DR, Burns JL, Ramsey BW, Miller SI.

Mol Microbiol. 2007 Apr;64(2):512-33.


Acquisition and evolution of the exoU locus in Pseudomonas aeruginosa.

Kulasekara BR, Kulasekara HD, Wolfgang MC, Stevens L, Frank DW, Lory S.

J Bacteriol. 2006 Jun;188(11):4037-50.


A novel two-component system controls the expression of Pseudomonas aeruginosa fimbrial cup genes.

Kulasekara HD, Ventre I, Kulasekara BR, Lazdunski A, Filloux A, Lory S.

Mol Microbiol. 2005 Jan;55(2):368-80.


Orientational control of fimE expression in Escherichia coli.

Sohanpal BK, Kulasekara HD, Bonnen A, Blomfield IC.

Mol Microbiol. 2001 Oct;42(2):483-94.


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