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Evaluation of Novel Prostate-Specific Membrane Antigen-Targeted Near-Infrared Imaging Agent for Fluorescence-Guided Surgery for Prostate Cancer.

Kularatne SA, Thomas M, Myers CH, Gagare P, Kanduluru AK, Crain CJ, Cichocki BN.

Clin Cancer Res. 2018 Sep 10. pii: clincanres.0803.2018. doi: 10.1158/1078-0432.CCR-18-0803. [Epub ahead of print]


Intra-aural tick bite causing unilateral facial nerve palsy in 29 cases over 16 years in Kandy, Sri Lanka: is rickettsial aetiology possible?

Kularatne SAM, Fernando R, Selvaratnam S, Narampanawa C, Weerakoon K, Wickramasinghe S, Pathirage M, Weerasinghe V, Bandara A, Rajapakse J.

BMC Infect Dis. 2018 Aug 22;18(1):418. doi: 10.1186/s12879-018-3338-8.


Bartter syndrome-like phenotype in a patient with diabetes: a case report.

Dalugama C, Pathirage M, Kularatne SAM.

J Med Case Rep. 2018 Aug 17;12(1):222. doi: 10.1186/s13256-018-1752-6.


Value of peripheral blood count for dengue severity prediction.

Ralapanawa U, Alawattegama ATM, Gunrathne M, Tennakoon S, Kularatne SAM, Jayalath T.

BMC Res Notes. 2018 Jun 20;11(1):400. doi: 10.1186/s13104-018-3505-4.


Delayed presentation of severe rhabdomyolysis leading to acute kidney injury following atorvastatin-gemfibrozil combination therapy: a case report.

Dalugama C, Pathirage M, Kularatne SAM.

J Med Case Rep. 2018 May 22;12(1):143. doi: 10.1186/s13256-018-1685-0.


Development of a Small Molecule Tubulysin B Conjugate for Treatment of Carbonic Anhydrase IX Receptor Expressing Cancers.

Marks IS, Gardeen SS, Kurdziel SJ, Nicolaou ST, Woods JE, Kularatne SA, Low PS.

Mol Pharm. 2018 Jun 4;15(6):2289-2296. doi: 10.1021/acs.molpharmaceut.8b00139. Epub 2018 May 1.


Cardiac arrest and atrial fibrillation in a patient after hump-nosed pit viper (Hypnale hypnale) bite.

Namal Rathnayaka RMMK, Nishanthi Ranathunga PEA, Ranaweera J, Jayasekara K, Kularatne SAM.

Toxicon. 2018 Jun 15;148:33-39. doi: 10.1016/j.toxicon.2018.03.014. Epub 2018 Mar 31.


An open label trial of folate receptor-targeted intraoperative molecular imaging to localize pulmonary squamous cell carcinomas.

Predina JD, Newton AD, Xia L, Corbett C, Connolly C, Shin M, Sulyok LF, Litzky L, Deshpande C, Nie S, Kularatne SA, Low PS, Singhal S.

Oncotarget. 2018 Feb 5;9(17):13517-13529. doi: 10.18632/oncotarget.24399. eCollection 2018 Mar 2.


Clinico-epidemiology of arthropod stings and bites in primary hospitals of North Western province of Sri Lanka.

Kularatne SAM, Shahmy S, Rathnayake SS, Dawson AH.

Clin Toxicol (Phila). 2018 Mar 6:1-6. doi: 10.1080/15563650.2018.1447120. [Epub ahead of print]


Microangiopathic Hemolytic Anemia Following Three Different Species of Hump-Nosed Pit Viper (Genus: Hypnale) Envenoming in Sri Lanka.

Namal Rathnayaka RMMK, Ranathunga AN, Kularatne SAM, Rajapakse J, Ranasinghe S, Jayathunga R.

Wilderness Environ Med. 2018 Mar;29(1):94-101. doi: 10.1016/j.wem.2017.11.003. Epub 2018 Feb 1. Erratum in: Wilderness Environ Med. 2018 Jun;29(2):285-286.


Identification of a Folate Receptor-Targeted Near-Infrared Molecular Contrast Agent to Localize Pulmonary Adenocarcinomas.

Predina JD, Newton AD, Connolly C, Dunbar A, Baldassari M, Deshpande C, Cantu E 3rd, Stadanlick J, Kularatne SA, Low PS, Singhal S.

Mol Ther. 2018 Feb 7;26(2):390-403. doi: 10.1016/j.ymthe.2017.10.016. Epub 2017 Oct 26.


A prospective cohort study of the effectiveness of the primary hospital management of all snakebites in Kurunegala district of Sri Lanka.

Shahmy S, Kularatne SAM, Rathnayake SS, Dawson AH.

PLoS Negl Trop Dis. 2017 Aug 21;11(8):e0005847. doi: 10.1371/journal.pntd.0005847. eCollection 2017 Aug.


Revisiting clinico-epidemiological pattern of human rickettsial infections in the central region of Sri Lanka: a hospital based descriptive study.

Weerakoon KG, Kularatne SAM, Rajapakse J, Adikari S, Udayawarna K.

BMC Res Notes. 2017 Aug 11;10(1):400. doi: 10.1186/s13104-017-2727-1.


Prolonged Coagulopathy, Ecchymoses, and Microangiopathic Hemolytic Anemia Following Hump-Nosed Pit Viper (Hypnale hypnale) Bite in Sri Lanka.

Namal Rathnayaka RMMK, Kularatne SAM, Ranathunga AN, Kumarasinghe M, Rajapakse J, Ranasinghe S.

Wilderness Environ Med. 2017 Sep;28(3):253-258. doi: 10.1016/j.wem.2017.05.005. Epub 2017 Jul 26.


Intraoperative Molecular Imaging Combined With Positron Emission Tomography Improves Surgical Management of Peripheral Malignant Pulmonary Nodules.

Predina JD, Newton AD, Keating J, Barbosa EM Jr, Okusanya O, Xia L, Dunbar A, Connolly C, Baldassari MP, Mizelle J, Delikatny EJ, Kucharczuk JC, Deshpande C, Kularatne SA, Low P, Drebin J, Singhal S.

Ann Surg. 2017 Sep;266(3):479-488. doi: 10.1097/SLA.0000000000002382.


Epidemiology and clinical features of Green pit viper (Trimeresurus trigonocephalus) envenoming in Sri Lanka.

Namal Rathnayaka RMMK, Ranathunga PEAN, Kularatne SAM.

Toxicon. 2017 Oct;137:99-105. doi: 10.1016/j.toxicon.2017.07.017. Epub 2017 Jul 21.


Hematological and plasma biochemical parameters in a wild population of Naja naja (Linnaeus, 1758) in Sri Lanka.

Dissanayake DSB, Thewarage LD, Manel Rathnayake RMP, Kularatne SAM, Ranasinghe JGS, Jayantha Rajapakse RPV.

J Venom Anim Toxins Incl Trop Dis. 2017 Feb 13;23:8. doi: 10.1186/s40409-017-0098-7. eCollection 2017.


Coagulopathy and extensive local swelling following Green pit viper (Trimeresurus trigonocephalus) envenoming in Sri Lanka.

Namal Rathnayaka RM, Kularatne SA, Ranathunga PE.

Toxicon. 2017 Apr;129:95-99. doi: 10.1016/j.toxicon.2017.02.011. Epub 2017 Feb 16.


Two rare case reports of confirmed Ceylon krait (Bungarus ceylonicus) envenoming in Sri Lanka.

Namal Rathnayaka RM, Kularatne SA, Kumarasinghe KD, Jeganadan K, Ranathunga PE.

Toxicon. 2017 Mar 1;127:44-48. doi: 10.1016/j.toxicon.2017.01.003. Epub 2017 Jan 4.


Ischemic brain infarcts and intracranial haemorrhages following Russell's viper (Daboia russelii) bite in Sri Lanka.

Namal Rathnayaka RM, Kularatne SA, Kumarasinghe KD, Ranaweera J, Nishanthi Ranathunga PE.

Toxicon. 2017 Jan;125:70-73. doi: 10.1016/j.toxicon.2016.11.253. Epub 2016 Nov 19.


Efficacy of intravenous hydrocortisone administered 2-4 h prior to antivenom as prophylaxis against adverse drug reactions to snake antivenom in Sri Lanka: An open labelled randomized controlled trial.

Kularatne SA, Weerakoon K, Silva A, Maduwage K, Walathara C, Rathnayake I, Medagedara S, Paranagama R, Mendis S, Kumarasiri PV.

Toxicon. 2016 Sep 15;120:159-65. doi: 10.1016/j.toxicon.2016.08.011. Epub 2016 Aug 13.


First Reported Case of Fatal Stinging by the Large Carpenter Bee Xylocopa tranquebarica.

Kularatne SA, Raveendran S, Edirisinghe J, Karunaratne I, Weerakoon K.

Wilderness Environ Med. 2016 Jun;27(2):262-5. doi: 10.1016/j.wem.2015.12.018. Epub 2016 Apr 6.


A Pan-Dengue Virus Reverse Transcription-Insulated Isothermal PCR Assay Intended for Point-of-Need Diagnosis of Dengue Virus Infection by Use of the POCKIT Nucleic Acid Analyzer.

Go YY, Rajapakse RPVJ, Kularatne SAM, Lee PA, Ku KB, Nam S, Chou PH, Tsai YL, Liu YL, Chang HG, Wang HT, Balasuriya UBR.

J Clin Microbiol. 2016 Jun;54(6):1528-1535. doi: 10.1128/JCM.00225-16. Epub 2016 Mar 30.


Pattern of animal bites and post exposure prophylaxis in rabies: A five year study in a tertiary care unit in Sri Lanka.

Kularatne SA, Ralapanawa DM, Weerakoon K, Bokalamulla UK, Abagaspitiya N.

BMC Infect Dis. 2016 Feb 4;16:62. doi: 10.1186/s12879-016-1394-5.


Guillain-Barre syndrome following dengue fever and literature review.

Ralapanawa DM, Kularatne SA, Jayalath WA.

BMC Res Notes. 2015 Nov 27;8:729. doi: 10.1186/s13104-015-1672-0. Review.


Comparison of Folate Receptor Targeted Optical Contrast Agents for Intraoperative Molecular Imaging.

De Jesus E, Keating JJ, Kularatne SA, Jiang J, Judy R, Predina J, Nie S, Low P, Singhal S.

Int J Mol Imaging. 2015;2015:469047. doi: 10.1155/2015/469047. Epub 2015 Sep 28.


Dengue fever.

Kularatne SA.

BMJ. 2015 Sep 15;351:h4661. doi: 10.1136/bmj.h4661. Review. No abstract available.


Trends of fluid requirement in dengue fever and dengue haemorrhagic fever: a single centre experience in Sri Lanka.

Kularatne SA, Weerakoon KG, Munasinghe R, Ralapanawa UK, Pathirage M.

BMC Res Notes. 2015 Apr 8;8:130. doi: 10.1186/s13104-015-1085-0.


Kounis syndrome secondary to amoxicillin/clavulanic acid administration: a case report and review of literature.

Ralapanawa DM, Kularatne SA.

BMC Res Notes. 2015 Mar 26;8:97. doi: 10.1186/s13104-015-1072-5. Review.


Intentional ingestion of Strychnos nux-vomica seeds causing severe muscle spasms and cardiac arrest: a postmortem report.

Fernando K, Jayasekara K, Warushahennadi J, Kumarasinghe I, Weerakoon K, Kularatne SA.

Wilderness Environ Med. 2015 Mar;26(1):101-2. doi: 10.1016/j.wem.2014.08.006. No abstract available.


A case of Kounis syndrome after a hornet sting and literature review.

Ralapanawa DM, Kularatne SA.

BMC Res Notes. 2014 Dec 3;7:867. doi: 10.1186/1756-0500-7-867. Review.


Clinico-epidemiology of stings and envenoming of Hottentotta tamulus (Scorpiones: Buthidae), the Indian red scorpion from Jaffna Peninsula in northern Sri Lanka.

Kularatne SA, Dinamithra NP, Sivansuthan S, Weerakoon KG, Thillaimpalam B, Kalyanasundram V, Ranawana KB.

Toxicon. 2015 Jan;93:85-9. doi: 10.1016/j.toxicon.2014.11.225. Epub 2014 Nov 14.


First reported case of systemic envenoming by the Sri Lankan keelback (Balanophis ceylonensis).

Fernando WK, Kularatne SA, Wathudura SP, de Silva A, Mori A, Mahaulpatha D.

Toxicon. 2015 Jan;93:20-3. doi: 10.1016/j.toxicon.2014.11.219. Epub 2014 Nov 6.


Cutaneous manifestations of spotted fever rickettsial infections in the Central Province of Sri Lanka: a descriptive study.

Weerakoon K, Kularatne SA, Rajapakse J, Adikari S, Waduge R.

PLoS Negl Trop Dis. 2014 Sep 18;8(9):e3179. doi: 10.1371/journal.pntd.0003179. eCollection 2014 Sep.


A CXCR4-targeted site-specific antibody-drug conjugate.

Kularatne SA, Deshmukh V, Ma J, Tardif V, Lim RK, Pugh HM, Sun Y, Manibusan A, Sellers AJ, Barnett RS, Srinagesh S, Forsyth JS, Hassenpflug W, Tian F, Javahishvili T, Felding-Habermann B, Lawson BR, Kazane SA, Schultz PG.

Angew Chem Int Ed Engl. 2014 Oct 27;53(44):11863-7. doi: 10.1002/anie.201408103. Epub 2014 Sep 11.


Long term outcome of acute kidney injury due to leptospirosis? A longitudinal study in Sri Lanka.

Herath NJ, Kularatne SA, Weerakoon KG, Wazil A, Subasinghe N, Ratnatunga NV.

BMC Res Notes. 2014 Jun 25;7:398. doi: 10.1186/1756-0500-7-398.


Fatal acute pulmonary oedema and acute renal failure following multiple wasp/hornet (Vespa affinis) stings in Sri Lanka: two case reports.

Kularatne K, Kannangare T, Jayasena A, Jayasekera A, Waduge R, Weerakoon K, Kularatne SA.

J Med Case Rep. 2014 Jun 13;8:188. doi: 10.1186/1752-1947-8-188.


Thrombotic microangiopathy following Russell's viper (Daboia russelii) envenoming in Sri Lanka: a case report.

Kularatne SA, Wimalasooriya S, Nazar K, Maduwage K.

Ceylon Med J. 2014 Mar;59(1):29-30. doi: 10.4038/cmj.v59i1.6738. No abstract available.


Extensive haemorrhagic necrosis of liver is an unpredictable fatal complication in dengue infection: a postmortem study.

Kularatne SA, Imbulpitiya IV, Abeysekera RA, Waduge RN, Rajapakse RP, Weerakoon KG.

BMC Infect Dis. 2014 Mar 14;14:141. doi: 10.1186/1471-2334-14-141.


Revisiting Russell's viper (Daboia russelii) bite in Sri Lanka: is abdominal pain an early feature of systemic envenoming?

Kularatne SA, Silva A, Weerakoon K, Maduwage K, Walathara C, Paranagama R, Mendis S.

PLoS One. 2014 Feb 26;9(2):e90198. doi: 10.1371/journal.pone.0090198. eCollection 2014.


Recruiting cytotoxic T cells to folate-receptor-positive cancer cells.

Kularatne SA, Deshmukh V, Gymnopoulos M, Biroc SL, Xia J, Srinagesh S, Sun Y, Zou N, Shimazu M, Pinkstaff J, Ensari S, Knudsen N, Manibusan A, Axup J, Kim C, Smider V, Javahishvili T, Schultz PG.

Angew Chem Int Ed Engl. 2013 Nov 11;52(46):12101-12104. doi: 10.1002/anie.201306866. Epub 2013 Sep 25. No abstract available.


Venomous snake bites, scorpions, and spiders.

Kularatne SA, Senanayake N.

Handb Clin Neurol. 2014;120:987-1001. doi: 10.1016/B978-0-7020-4087-0.00066-8. Review.


Enhydrina schistosa (Elapidae: Hydrophiinae) the most dangerous sea snake in Sri Lanka: three case studies of severe envenoming.

Kularatne SA, Hettiarachchi R, Dalpathadu J, Mendis AS, Appuhamy PD, Zoysa HD, Maduwage K, Weerasinghe VS, de Silva A.

Toxicon. 2014 Jan;77:78-86. doi: 10.1016/j.toxicon.2013.10.031. Epub 2013 Nov 12.


Synthesis and activity of a folate targeted monodisperse PEG camptothecin conjugate.

Henne WA, Kularatne SA, Hakenjos J, Carron JD, Henne KL.

Bioorg Med Chem Lett. 2013 Nov 1;23(21):5810-3. doi: 10.1016/j.bmcl.2013.08.113. Epub 2013 Sep 7.


Does Carica papaya leaf-extract increase the platelet count? An experimental study in a murine model.

Dharmarathna SL, Wickramasinghe S, Waduge RN, Rajapakse RP, Kularatne SA.

Asian Pac J Trop Biomed. 2013 Sep;3(9):720-4. doi: 10.1016/S2221-1691(13)60145-8.


Serological evidence for exposure of dogs to Rickettsia conorii, Rickettsia typhi, and Orientia tsutsugamushi in Sri Lanka.

Nanayakkara DM, Rajapakse RP, Wickramasinghe S, Kularatne SA.

Vector Borne Zoonotic Dis. 2013 Aug;13(8):545-9. doi: 10.1089/vbz.2012.1049. Epub 2013 May 13.


Rickettsioses in the central hills of Sri Lanka: serological evidence of increasing burden of spotted fever group.

Kularatne SA, Rajapakse RP, Wickramasinghe WM, Nanayakkara DM, Budagoda SS, Weerakoon KG, Edirisinghe JS, Premaratna R.

Int J Infect Dis. 2013 Nov;17(11):e988-92. doi: 10.1016/j.ijid.2013.05.014. Epub 2013 Jul 17.


Comparative analysis of folate derived PET imaging agents with [(18)F]-2-fluoro-2-deoxy-d-glucose using a rodent inflammatory paw model.

Kularatne SA, Bélanger MJ, Meng X, Connolly BM, Vanko A, Suresch DL, Guenther I, Wang S, Low PS, McQuade P, Trotter DG.

Mol Pharm. 2013 Aug 5;10(8):3103-11. doi: 10.1021/mp4001684. Epub 2013 Jul 24.


Fatal pulmonary haemorrhage following adenovirus infection.

Abeysekera RA, Kularatne SA, Noordeen E, Ratnatunga NV, Bandara JM.

Ceylon Med J. 2013 Jun;58(2):84-6. doi: 10.4038/cmj.v58i2.5686. No abstract available.


Development of tumor-targeted near infrared probes for fluorescence guided surgery.

Kelderhouse LE, Chelvam V, Wayua C, Mahalingam S, Poh S, Kularatne SA, Low PS.

Bioconjug Chem. 2013 Jun 19;24(6):1075-80. doi: 10.1021/bc400131a. Epub 2013 May 21.


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