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Evolution of herpetology and management of snakebite in Sri Lanka

Kularatne SAM, De Silva A, Dalugame C, Fernando M.

Ceylon Med J. 2019 Dec 31;64(4):121-124. No abstract available.


Thrombotic Microangiopathy Following Hypnale zara (Hump-Nosed Pit Viper) Envenoming: The First Known Case Report from Sri Lanka.

Namal Rathnayaka RMMK, Nishanthi Ranathunga PEA, Kularatne SAM.

Wilderness Environ Med. 2020 Mar;31(1):71-77. doi: 10.1016/j.wem.2019.08.009. Epub 2019 Dec 20.


Systemic bleeding including pulmonary haemorrhage following hump-nosed pit viper (Hypnale hypnale) envenoming: A case report from Sri Lanka.

Rathnayaka RMMKN, Ranathunga PEAN, Kularatne SAM.

Toxicon. 2019 Dec;170:21-28. doi: 10.1016/j.toxicon.2019.09.009. Epub 2019 Sep 9.


Study protocol: characterising the clinical, epidemiological and aetiological aspects of leptospirosis in Sri Lanka: a hospital based clinico-epidemiological study.

Agampodi S, Warnasekara J, Jayasundara D, Senawirathna I, Gamage C, Kularatne S, Siribaddana S, Maththias M, Vinetz J.

BMJ Open. 2019 Sep 11;9(9):e027850. doi: 10.1136/bmjopen-2018-027850.


Developing and evaluating an intervention to improve care and reduce costs of rabies postexposure therapy: an observational quality improvement initiative in selected vaccination units in Sri Lanka.

Gamalathge PU, Carter HE, Wimalaratne O, Kularatne S.

Int J Evid Based Healthc. 2019 Sep;17(3):157-163. doi: 10.1097/XEB.0000000000000172.


Para median thalamic syndrome due to occlusion of the artery of Percheron: A rare case of stroke

Weerasinghe WS, Kularatne SAM, Pathirage LPMMK.

Ceylon Med J. 2019 Mar 31;64(1):30-31. No abstract available.


A case of delayed neurological manifestation following carbon monoxide poisoning in Sri Lanka: epidemiology of exposure and literature review.

Kumarihamy P, Kularatne SAM, Pathirage M, Gunaratne WMSN, Waduge R.

BMC Pharmacol Toxicol. 2019 Apr 5;20(1):17. doi: 10.1186/s40360-019-0295-9.


Thrombotic Microangiopathy, Hemolytic Uremic Syndrome, and Thrombotic Thrombocytopenic Purpura Following Hump-nosed Pit Viper (Genus: Hypnale) Envenoming in Sri Lanka.

Namal Rathnayaka R, Ranathunga PAN, Kularatne SA.

Wilderness Environ Med. 2019 Mar;30(1):66-78. doi: 10.1016/j.wem.2018.10.003. Epub 2019 Jan 31.


Spotted fever rickettsioses causing myocarditis and ARDS: a case from Sri Lanka.

Herath HMLY, Jayasundara JMHD, Senadhira SDN, Kularatne SAM, Kularatne WKS.

BMC Infect Dis. 2018 Dec 29;18(1):705. doi: 10.1186/s12879-018-3631-6.


Heart and liver are infected in fatal cases of dengue: three PCR based case studies.

Kularatne SAM, Rajapakse MM, Ralapanawa U, Waduge R, Pathirage LPMMK, Rajapakse RPVJ.

BMC Infect Dis. 2018 Dec 19;18(1):681. doi: 10.1186/s12879-018-3603-x.


Series of 10 dengue fever cases with unusual presentations and complications in Sri Lanka: a single centre experience in 2016.

Kularatne SAM, Ralapanawa U, Dalugama C, Jayasinghe J, Rupasinghe S, Kumarihamy P.

BMC Infect Dis. 2018 Dec 18;18(1):674. doi: 10.1186/s12879-018-3596-5.


Kidney injury following envenoming by hump-nosed pit viper (Genus: Hypnale) in Sri Lanka: proven and probable cases.

Rathnayaka RMMKN, Ranathunga PEAN, Kularatne SAM.

Trans R Soc Trop Med Hyg. 2019 Mar 1;113(3):131-142. doi: 10.1093/trstmh/try120.


An unusual case of gross myoglobinuria in a child following Russell's viper (Daboia russelii) envenomation.

Dissanayake PV, Muthukumarana TGW, Aslam WAM, Chaminda SAA, Munasinghe TS, Kularatne SAM.

Toxicon. 2019 Jan;157:77-79. doi: 10.1016/j.toxicon.2018.11.299. Epub 2018 Nov 16.


The Venom of Spectacled Cobra (Elapidae: Naja naja): In Vitro Study from Distinct Geographical Origins in Sri Lanka.

Dissanayake DSB, Thewarage LD, Waduge RN, Ranasinghe JGS, Kularatne SAM, Rajapakse RPVJ.

J Toxicol. 2018 Sep 27;2018:7358472. doi: 10.1155/2018/7358472. eCollection 2018.


Evaluation of Novel Tumor-Targeted Near-Infrared Probe for Fluorescence-Guided Surgery of Cancer.

Mahalingam SM, Kularatne SA, Myers CH, Gagare P, Norshi M, Liu X, Singhal S, Low PS.

J Med Chem. 2018 Nov 8;61(21):9637-9646. doi: 10.1021/acs.jmedchem.8b01115. Epub 2018 Oct 19.


Evaluation of Novel Prostate-Specific Membrane Antigen-Targeted Near-Infrared Imaging Agent for Fluorescence-Guided Surgery of Prostate Cancer.

Kularatne SA, Thomas M, Myers CH, Gagare P, Kanduluru AK, Crian CJ, Cichocki BN.

Clin Cancer Res. 2019 Jan 1;25(1):177-187. doi: 10.1158/1078-0432.CCR-18-0803. Epub 2018 Sep 10.


Intra-aural tick bite causing unilateral facial nerve palsy in 29 cases over 16 years in Kandy, Sri Lanka: is rickettsial aetiology possible?

Kularatne SAM, Fernando R, Selvaratnam S, Narampanawa C, Weerakoon K, Wickramasinghe S, Pathirage M, Weerasinghe V, Bandara A, Rajapakse J.

BMC Infect Dis. 2018 Aug 22;18(1):418. doi: 10.1186/s12879-018-3338-8.


Bartter syndrome-like phenotype in a patient with diabetes: a case report.

Dalugama C, Pathirage M, Kularatne SAM.

J Med Case Rep. 2018 Aug 17;12(1):222. doi: 10.1186/s13256-018-1752-6.


Value of peripheral blood count for dengue severity prediction.

Ralapanawa U, Alawattegama ATM, Gunrathne M, Tennakoon S, Kularatne SAM, Jayalath T.

BMC Res Notes. 2018 Jun 20;11(1):400. doi: 10.1186/s13104-018-3505-4.


Delayed presentation of severe rhabdomyolysis leading to acute kidney injury following atorvastatin-gemfibrozil combination therapy: a case report.

Dalugama C, Pathirage M, Kularatne SAM.

J Med Case Rep. 2018 May 22;12(1):143. doi: 10.1186/s13256-018-1685-0.


Development of a Small Molecule Tubulysin B Conjugate for Treatment of Carbonic Anhydrase IX Receptor Expressing Cancers.

Marks IS, Gardeen SS, Kurdziel SJ, Nicolaou ST, Woods JE, Kularatne SA, Low PS.

Mol Pharm. 2018 Jun 4;15(6):2289-2296. doi: 10.1021/acs.molpharmaceut.8b00139. Epub 2018 May 1.


Cardiac arrest and atrial fibrillation in a patient after hump-nosed pit viper (Hypnale hypnale) bite.

Namal Rathnayaka RMMK, Nishanthi Ranathunga PEA, Ranaweera J, Jayasekara K, Kularatne SAM.

Toxicon. 2018 Jun 15;148:33-39. doi: 10.1016/j.toxicon.2018.03.014. Epub 2018 Mar 31.


An open label trial of folate receptor-targeted intraoperative molecular imaging to localize pulmonary squamous cell carcinomas.

Predina JD, Newton AD, Xia L, Corbett C, Connolly C, Shin M, Sulyok LF, Litzky L, Deshpande C, Nie S, Kularatne SA, Low PS, Singhal S.

Oncotarget. 2018 Feb 5;9(17):13517-13529. doi: 10.18632/oncotarget.24399. eCollection 2018 Mar 2.


Clinico-epidemiology of arthropod stings and bites in primary hospitals of North Western province of Sri Lanka.

Kularatne SAM, Shahmy S, Rathnayake SS, Dawson AH.

Clin Toxicol (Phila). 2018 Oct;56(10):880-885. doi: 10.1080/15563650.2018.1447120. Epub 2018 Mar 6.


Microangiopathic Hemolytic Anemia Following Three Different Species of Hump-Nosed Pit Viper (Genus: Hypnale) Envenoming in Sri Lanka.

Namal Rathnayaka RMMK, Ranathunga AN, Kularatne SAM, Rajapakse J, Ranasinghe S, Jayathunga R.

Wilderness Environ Med. 2018 Mar;29(1):94-101. doi: 10.1016/j.wem.2017.11.003. Epub 2018 Feb 1. Erratum in: Wilderness Environ Med. 2018 Jun;29(2):285-286.


Identification of a Folate Receptor-Targeted Near-Infrared Molecular Contrast Agent to Localize Pulmonary Adenocarcinomas.

Predina JD, Newton AD, Connolly C, Dunbar A, Baldassari M, Deshpande C, Cantu E 3rd, Stadanlick J, Kularatne SA, Low PS, Singhal S.

Mol Ther. 2018 Feb 7;26(2):390-403. doi: 10.1016/j.ymthe.2017.10.016. Epub 2017 Oct 26.


A prospective cohort study of the effectiveness of the primary hospital management of all snakebites in Kurunegala district of Sri Lanka.

Shahmy S, Kularatne SAM, Rathnayake SS, Dawson AH.

PLoS Negl Trop Dis. 2017 Aug 21;11(8):e0005847. doi: 10.1371/journal.pntd.0005847. eCollection 2017 Aug.


Revisiting clinico-epidemiological pattern of human rickettsial infections in the central region of Sri Lanka: a hospital based descriptive study.

Weerakoon KG, Kularatne SAM, Rajapakse J, Adikari S, Udayawarna K.

BMC Res Notes. 2017 Aug 11;10(1):400. doi: 10.1186/s13104-017-2727-1.


Prolonged Coagulopathy, Ecchymoses, and Microangiopathic Hemolytic Anemia Following Hump-Nosed Pit Viper (Hypnale hypnale) Bite in Sri Lanka.

Namal Rathnayaka RMMK, Kularatne SAM, Ranathunga AN, Kumarasinghe M, Rajapakse J, Ranasinghe S.

Wilderness Environ Med. 2017 Sep;28(3):253-258. doi: 10.1016/j.wem.2017.05.005. Epub 2017 Jul 26.


Intraoperative Molecular Imaging Combined With Positron Emission Tomography Improves Surgical Management of Peripheral Malignant Pulmonary Nodules.

Predina JD, Newton AD, Keating J, Barbosa EM Jr, Okusanya O, Xia L, Dunbar A, Connolly C, Baldassari MP, Mizelle J, Delikatny EJ, Kucharczuk JC, Deshpande C, Kularatne SA, Low P, Drebin J, Singhal S.

Ann Surg. 2017 Sep;266(3):479-488. doi: 10.1097/SLA.0000000000002382.


Epidemiology and clinical features of Green pit viper (Trimeresurus trigonocephalus) envenoming in Sri Lanka.

Namal Rathnayaka RMMK, Ranathunga PEAN, Kularatne SAM.

Toxicon. 2017 Oct;137:99-105. doi: 10.1016/j.toxicon.2017.07.017. Epub 2017 Jul 21.


Hematological and plasma biochemical parameters in a wild population of Naja naja (Linnaeus, 1758) in Sri Lanka.

Dissanayake DSB, Thewarage LD, Manel Rathnayake RMP, Kularatne SAM, Ranasinghe JGS, Jayantha Rajapakse RPV.

J Venom Anim Toxins Incl Trop Dis. 2017 Feb 13;23:8. doi: 10.1186/s40409-017-0098-7. eCollection 2017.


Coagulopathy and extensive local swelling following Green pit viper (Trimeresurus trigonocephalus) envenoming in Sri Lanka.

Namal Rathnayaka RM, Kularatne SA, Ranathunga PE.

Toxicon. 2017 Apr;129:95-99. doi: 10.1016/j.toxicon.2017.02.011. Epub 2017 Feb 16.


Two rare case reports of confirmed Ceylon krait (Bungarus ceylonicus) envenoming in Sri Lanka.

Namal Rathnayaka RM, Kularatne SA, Kumarasinghe KD, Jeganadan K, Ranathunga PE.

Toxicon. 2017 Mar 1;127:44-48. doi: 10.1016/j.toxicon.2017.01.003. Epub 2017 Jan 4.


Ischemic brain infarcts and intracranial haemorrhages following Russell's viper (Daboia russelii) bite in Sri Lanka.

Namal Rathnayaka RM, Kularatne SA, Kumarasinghe KD, Ranaweera J, Nishanthi Ranathunga PE.

Toxicon. 2017 Jan;125:70-73. doi: 10.1016/j.toxicon.2016.11.253. Epub 2016 Nov 19.


Efficacy of intravenous hydrocortisone administered 2-4 h prior to antivenom as prophylaxis against adverse drug reactions to snake antivenom in Sri Lanka: An open labelled randomized controlled trial.

Kularatne SA, Weerakoon K, Silva A, Maduwage K, Walathara C, Rathnayake I, Medagedara S, Paranagama R, Mendis S, Kumarasiri PV.

Toxicon. 2016 Sep 15;120:159-65. doi: 10.1016/j.toxicon.2016.08.011. Epub 2016 Aug 13.


First Reported Case of Fatal Stinging by the Large Carpenter Bee Xylocopa tranquebarica.

Kularatne SA, Raveendran S, Edirisinghe J, Karunaratne I, Weerakoon K.

Wilderness Environ Med. 2016 Jun;27(2):262-5. doi: 10.1016/j.wem.2015.12.018. Epub 2016 Apr 6.


A Pan-Dengue Virus Reverse Transcription-Insulated Isothermal PCR Assay Intended for Point-of-Need Diagnosis of Dengue Virus Infection by Use of the POCKIT Nucleic Acid Analyzer.

Go YY, Rajapakse RPVJ, Kularatne SAM, Lee PA, Ku KB, Nam S, Chou PH, Tsai YL, Liu YL, Chang HG, Wang HT, Balasuriya UBR.

J Clin Microbiol. 2016 Jun;54(6):1528-1535. doi: 10.1128/JCM.00225-16. Epub 2016 Mar 30.


Pattern of animal bites and post exposure prophylaxis in rabies: A five year study in a tertiary care unit in Sri Lanka.

Kularatne SA, Ralapanawa DM, Weerakoon K, Bokalamulla UK, Abagaspitiya N.

BMC Infect Dis. 2016 Feb 4;16:62. doi: 10.1186/s12879-016-1394-5.


Guillain-Barre syndrome following dengue fever and literature review.

Ralapanawa DM, Kularatne SA, Jayalath WA.

BMC Res Notes. 2015 Nov 27;8:729. doi: 10.1186/s13104-015-1672-0. Review.


Ascending aortic aneurysm caused by Mycobacterium tuberculosis.

Pathirana U, Kularatne S, Karunaratne S, Ranasinghe G, Fernando J.

BMC Res Notes. 2015 Nov 9;8:659. doi: 10.1186/s13104-015-1667-x.


Comparison of Folate Receptor Targeted Optical Contrast Agents for Intraoperative Molecular Imaging.

De Jesus E, Keating JJ, Kularatne SA, Jiang J, Judy R, Predina J, Nie S, Low P, Singhal S.

Int J Mol Imaging. 2015;2015:469047. doi: 10.1155/2015/469047. Epub 2015 Sep 28.


Dengue fever.

Kularatne SA.

BMJ. 2015 Sep 15;351:h4661. doi: 10.1136/bmj.h4661. Review. No abstract available.


Ortner's syndrome presenting as thoracic aortic aneurysm mimicking thoracic malignancy: a case report.

Pathirana U, Kularatne S, Handagala S, Ranasinghe G, Samarasinghe R.

J Med Case Rep. 2015 Jun 24;9:147. doi: 10.1186/s13256-015-0629-1.


Trends of fluid requirement in dengue fever and dengue haemorrhagic fever: a single centre experience in Sri Lanka.

Kularatne SA, Weerakoon KG, Munasinghe R, Ralapanawa UK, Pathirage M.

BMC Res Notes. 2015 Apr 8;8:130. doi: 10.1186/s13104-015-1085-0.


Kounis syndrome secondary to amoxicillin/clavulanic acid administration: a case report and review of literature.

Ralapanawa DM, Kularatne SA.

BMC Res Notes. 2015 Mar 26;8:97. doi: 10.1186/s13104-015-1072-5. Review.


Intentional ingestion of Strychnos nux-vomica seeds causing severe muscle spasms and cardiac arrest: a postmortem report.

Fernando K, Jayasekara K, Warushahennadi J, Kumarasinghe I, Weerakoon K, Kularatne SA.

Wilderness Environ Med. 2015 Mar;26(1):101-2. doi: 10.1016/j.wem.2014.08.006. No abstract available.


A case of Kounis syndrome after a hornet sting and literature review.

Ralapanawa DM, Kularatne SA.

BMC Res Notes. 2014 Dec 3;7:867. doi: 10.1186/1756-0500-7-867. Review.


Clinico-epidemiology of stings and envenoming of Hottentotta tamulus (Scorpiones: Buthidae), the Indian red scorpion from Jaffna Peninsula in northern Sri Lanka.

Kularatne SA, Dinamithra NP, Sivansuthan S, Weerakoon KG, Thillaimpalam B, Kalyanasundram V, Ranawana KB.

Toxicon. 2015 Jan;93:85-9. doi: 10.1016/j.toxicon.2014.11.225. Epub 2014 Nov 14.


First reported case of systemic envenoming by the Sri Lankan keelback (Balanophis ceylonensis).

Fernando WK, Kularatne SA, Wathudura SP, de Silva A, Mori A, Mahaulpatha D.

Toxicon. 2015 Jan;93:20-3. doi: 10.1016/j.toxicon.2014.11.219. Epub 2014 Nov 6.


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