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Items: 7

1.

Regulation of tankyrase activity by a catalytic domain dimer interface.

Fan C, Yarravarapu N, Chen H, Kulak O, Dasari P, Herbert J, Yamaguchi K, Lum L, Zhang X.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1780-1785. doi: 10.1016/j.bbrc.2018.07.113. Epub 2018 Jul 26.

2.

A synthetic combinatorial approach to disabling deviant Hedgehog signaling.

Fan CW, Yarravarapu N, Shi H, Kulak O, Kim J, Chen C, Lum L.

Sci Rep. 2018 Jan 18;8(1):1133. doi: 10.1038/s41598-018-19408-9.

3.

Role of the Exocyst Complex Component Sec6/8 in Genomic Stability.

Torres MJ, Pandita RK, Kulak O, Kumar R, Formstecher E, Horikoshi N, Mujoo K, Hunt CR, Zhao Y, Lum L, Zaman A, Yeaman C, White MA, Pandita TK.

Mol Cell Biol. 2015 Nov;35(21):3633-45. doi: 10.1128/MCB.00768-15. Epub 2015 Aug 17.

4.

Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.

Kulak O, Chen H, Holohan B, Wu X, He H, Borek D, Otwinowski Z, Yamaguchi K, Garofalo LA, Ma Z, Wright W, Chen C, Shay JW, Zhang X, Lum L.

Mol Cell Biol. 2015 Jul;35(14):2425-35. doi: 10.1128/MCB.00392-15. Epub 2015 May 4.

5.

Identification of therapeutic small-molecule leads in cultured cells using multiplexed pathway reporter readouts.

Kulak O, Yamaguchi K, Lum L.

Methods Mol Biol. 2015;1263:3-14. doi: 10.1007/978-1-4939-2269-7_1.

6.
7.

Genome-wide RNAi screen reveals disease-associated genes that are common to Hedgehog and Wnt signaling.

Jacob LS, Wu X, Dodge ME, Fan CW, Kulak O, Chen B, Tang W, Wang B, Amatruda JF, Lum L.

Sci Signal. 2011 Jan 25;4(157):ra4. doi: 10.1126/scisignal.2001225.

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