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Items: 1 to 50 of 78

1.

Renewal Theory as a Universal Quantitative Framework to Characterize Phase Singularity Regeneration in Mammalian Cardiac Fibrillation.

Dharmaprani D, Schopp M, Kuklik P, Chapman D, Lahiri A, Dykes L, Xiong F, Aguilar M, Strauss B, Mitchell L, Pope K, Meyer C, Willems S, Akar FG, Nattel S, McGavigan AD, Ganesan AN.

Circ Arrhythm Electrophysiol. 2019 Dec;12(12):e007569. doi: 10.1161/CIRCEP.119.007569. Epub 2019 Dec 9.

PMID:
31813270
2.

Editorial: Recent Advances in Understanding the Basic Mechanisms of Atrial Fibrillation Using Novel Computational Approaches.

Zhao J, Aslanidi O, Kuklik P, Lee G, Tse G, Niederer S, Vigmond EJ.

Front Physiol. 2019 Aug 20;10:1065. doi: 10.3389/fphys.2019.01065. eCollection 2019. No abstract available.

3.

Cardiac glial cells release neurotrophic S100B upon catheter-based treatment of atrial fibrillation.

Scherschel K, Hedenus K, Jungen C, Lemoine MD, Rübsamen N, Veldkamp MW, Klatt N, Lindner D, Westermann D, Casini S, Kuklik P, Eickholt C, Klöcker N, Shivkumar K, Christ T, Zeller T, Willems S, Meyer C.

Sci Transl Med. 2019 May 22;11(493). pii: eaav7770. doi: 10.1126/scitranslmed.aav7770.

PMID:
31118294
4.

High-Density Mapping and Ablation of Primary Nonfocal Left Atrial Tachycardia: Characterizing a Distinct Arrhythmogenic Substrate.

Schaeffer B, Akbulak RÖ, Jularic M, Moser J, Eickholt C, Schwarzl JM, Klatt N, Kuklik P, Meyer C, Willems S.

JACC Clin Electrophysiol. 2019 Apr;5(4):417-426. doi: 10.1016/j.jacep.2019.02.002. Epub 2019 Mar 27.

PMID:
31000095
5.

Temporal stability and specificity of high bipolar electrogram entropy regions in sustained atrial fibrillation: Implications for mapping.

Dharmaprani D, McGavigan AD, Chapman D, Kutlieh R, Thanigaimani S, Dykes L, Kalman J, Sanders P, Pope K, Kuklik P, Ganesan AN.

J Electrocardiol. 2019 Mar - Apr;53:18-27. doi: 10.1016/j.jelectrocard.2018.11.014. Epub 2018 Nov 20.

PMID:
30580097
6.

Differential pacing from two sites to diagnose risk of ventricular arrhythmia and death.

Nayyar S, Kuklik P, Tomlinson G, Suszko A, Chauhan VS.

Pacing Clin Electrophysiol. 2019 Feb;42(2):189-200. doi: 10.1111/pace.13566. Epub 2018 Dec 18.

PMID:
30515873
7.

Rotors Detected by Phase Analysis of Filtered, Epicardial Atrial Fibrillation Electrograms Colocalize With Regions of Conduction Block.

Podziemski P, Zeemering S, Kuklik P, van Hunnik A, Maesen B, Maessen J, Crijns HJ, Verheule S, Schotten U.

Circ Arrhythm Electrophysiol. 2018 Oct;11(10):e005858. doi: 10.1161/CIRCEP.117.005858.

8.

Information Theory and Atrial Fibrillation (AF): A Review.

Dharmaprani D, Dykes L, McGavigan AD, Kuklik P, Pope K, Ganesan AN.

Front Physiol. 2018 Jul 18;9:957. doi: 10.3389/fphys.2018.00957. eCollection 2018. Review.

9.

Impact of Intracardiac Neurons on Cardiac Electrophysiology and Arrhythmogenesis in an Ex Vivo Langendorff System.

Jungen C, Scherschel K, Bork NI, Kuklik P, Eickholt C, Kniep H, Klatt N, Willems S, Nikolaev VO, Meyer C.

J Vis Exp. 2018 May 22;(135). doi: 10.3791/57617.

PMID:
29889210
10.

Sympathetic and Parasympathetic Coactivation Induces Perturbed Heart Rate Dynamics in Patients with Paroxysmal Atrial Fibrillation.

Eickholt C, Jungen C, Drexel T, Alken F, Kuklik P, Muehlsteff J, Makimoto H, Hoffmann B, Kelm M, Ziegler D, Kloecker N, Willems S, Meyer C.

Med Sci Monit. 2018 Apr 11;24:2164-2172.

11.

Transient Rotor Activity During Prolonged 3-Dimensional Phase Mapping in Human Persistent Atrial Fibrillation.

Pathik B, Kalman JM, Walters T, Kuklik P, Zhao J, Madry A, Prabhu S, Nalliah C, Kistler P, Lee G.

JACC Clin Electrophysiol. 2018 Jan;4(1):72-83. doi: 10.1016/j.jacep.2017.06.005. Epub 2017 Sep 13.

12.

Contact force facilitates the achievement of an unexcitable ablation line during pulmonary vein isolation.

Schaeffer B, Willems S, Meyer C, Lüker J, Akbulak RÖ, Moser J, Jularic M, Eickholt C, Schwarzl JM, Gunawardene M, Kuklik P, Sultan A, Hoffmann BA, Steven D.

Clin Res Cardiol. 2018 Aug;107(8):632-641. doi: 10.1007/s00392-018-1228-0. Epub 2018 Mar 2.

PMID:
29500567
13.

Electrophysiologic features of protected channels in late postinfarction patients with and without spontaneous ventricular tachycardia.

Nayyar S, Wilson L, Ganesan A, Sullivan T, Kuklik P, Young G, Sanders P, Roberts-Thomson KC.

J Interv Card Electrophysiol. 2018 Jan;51(1):13-24. doi: 10.1007/s10840-017-0299-6. Epub 2017 Dec 13.

PMID:
29236200
14.

Absence of rotational activity detected using 2-dimensional phase mapping in the corresponding 3-dimensional phase maps in human persistent atrial fibrillation.

Pathik B, Kalman JM, Walters T, Kuklik P, Zhao J, Madry A, Sanders P, Kistler PM, Lee G.

Heart Rhythm. 2018 Feb;15(2):182-192. doi: 10.1016/j.hrthm.2017.09.010. Epub 2017 Sep 14.

PMID:
28917553
15.

Substrate characterization and catheter ablation in patients with scar-related ventricular tachycardia using ultra high-density 3-D mapping.

Nührich JM, Kaiser L, Akbulak RÖ, Schäffer BN, Eickholt C, Schwarzl M, Kuklik P, Moser J, Jularic M, Willems S, Meyer C.

J Cardiovasc Electrophysiol. 2017 Sep;28(9):1058-1067. doi: 10.1111/jce.13270. Epub 2017 Jul 3.

PMID:
28597532
16.

Spatiotemporal characteristics of atrial fibrillation electrograms: A novel marker for arrhythmia stability and termination.

Thanigaimani S, Brooks AG, Kuklik P, Twomey DJ, Franklin S, Noschka E, Chapman D, Pathak RK, Mahajan R, Sanders P, Lau DH.

J Arrhythm. 2017 Feb;33(1):40-48. doi: 10.1016/j.joa.2016.05.009. Epub 2016 Jul 27.

17.

How disruption of endo-epicardial electrical connections enhances endo-epicardial conduction during atrial fibrillation.

Gharaviri A, Verheule S, Eckstein J, Potse M, Kuklik P, Kuijpers NH, Schotten U.

Europace. 2017 Feb 1;19(2):308-318. doi: 10.1093/europace/euv445.

PMID:
28175261
18.

Disruption of cardiac cholinergic neurons enhances susceptibility to ventricular arrhythmias.

Jungen C, Scherschel K, Eickholt C, Kuklik P, Klatt N, Bork N, Salzbrunn T, Alken F, Angendohr S, Klene C, Mester J, Klöcker N, Veldkamp MW, Schumacher U, Willems S, Nikolaev VO, Meyer C.

Nat Commun. 2017 Jan 27;8:14155. doi: 10.1038/ncomms14155.

19.

Development of Time- and Voltage-Domain Mapping (V-T-Mapping) to Localize Ventricular Tachycardia Channels During Sinus Rhythm.

Nayyar S, Kuklik P, Ganesan AN, Sullivan TR, Wilson L, Young GD, Sanders P, Roberts-Thomson KC.

Circ Arrhythm Electrophysiol. 2016 Dec;9(12). pii: e004050.

PMID:
27913399
20.

Local Electrical Dyssynchrony during Atrial Fibrillation: Theoretical Considerations and Initial Catheter Ablation Results.

Kuklik P, Schäffer B, Hoffmann BA, Ganesan AN, Schreiber D, Moser JM, Akbulak RÖ, Sultan A, Steven D, Maesen B, Schotten U, Meyer C, Willems S.

PLoS One. 2016 Oct 25;11(10):e0164236. doi: 10.1371/journal.pone.0164236. eCollection 2016.

21.

Development of nonfibrotic left ventricular hypertrophy in an ANG II-induced chronic ovine hypertension model.

Klatt N, Scherschel K, Schad C, Lau D, Reitmeier A, Kuklik P, Muellerleile K, Yamamura J, Zeller T, Steven D, Baldus S, Schäffer B, Jungen C, Eickholt C, Wassilew K, Schwedhelm E, Willems S, Meyer C.

Physiol Rep. 2016 Sep;4(17). pii: e12897. doi: 10.14814/phy2.12897.

22.

Influence of periprocedural anticoagulation strategies on complication rate and hospital stay in patients undergoing catheter ablation for persistent atrial fibrillation.

Gunawardene M, Willems S, Schäffer B, Moser J, Akbulak RÖ, Jularic M, Eickholt C, Nührich J, Meyer C, Kuklik P, Sehner S, Czerner V, Hoffmann BA.

Clin Res Cardiol. 2017 Jan;106(1):38-48. doi: 10.1007/s00392-016-1021-x. Epub 2016 Jul 19.

PMID:
27435077
23.

Characterization, Mapping, and Ablation of Complex Atrial Tachycardia: Initial Experience With a Novel Method of Ultra High-Density 3D Mapping.

Schaeffer B, Hoffmann BA, Meyer C, Akbulak RÖ, Moser J, Jularic M, Eickholt C, Nührich JM, Kuklik P, Willems S.

J Cardiovasc Electrophysiol. 2016 Oct;27(10):1139-1150. doi: 10.1111/jce.13035. Epub 2016 Aug 4.

PMID:
27325527
24.

Mismatch Between Cardiac Perfusion, Sympathetic Innervation, and Left Ventricular Electroanatomical Map in a Patient with Recurrent Ventricular Tachycardia.

Jungen C, von Gogh G, Schmitt C, Kuklik P, Hoffmann B, Nakajima K, Willems S, Mester J, Meyer C.

Am J Case Rep. 2016 Apr 25;17:280-2.

25.

Identification of Rotors during Human Atrial Fibrillation Using Contact Mapping and Phase Singularity Detection: Technical Considerations.

Kuklik P, Zeemering S, van Hunnik A, Maesen B, Pison L, Lau DH, Maessen J, Podziemski P, Meyer C, Schaffer B, Crijns H, Willems S, Schotten U.

IEEE Trans Biomed Eng. 2017 Feb;64(2):310-318. doi: 10.1109/TBME.2016.2554660. Epub 2016 Apr 15.

PMID:
27101596
26.

Atrial Fibrillation Complexity Parameters Derived From Surface ECGs Predict Procedural Outcome and Long-Term Follow-Up of Stepwise Catheter Ablation for Atrial Fibrillation.

Lankveld T, Zeemering S, Scherr D, Kuklik P, Hoffmann BA, Willems S, Pieske B, Haïssaguerre M, Jaïs P, Crijns HJ, Schotten U.

Circ Arrhythm Electrophysiol. 2016 Feb;9(2):e003354. doi: 10.1161/CIRCEP.115.003354.

PMID:
26823480
27.

Simultaneous conduction mapping and intracellular membrane potential recording in isolated atria.

Neo M, Morris DG, Kuklik P, Lau DH, Dimitri H, Lim WW, Sanders P, Saint DA.

Can J Physiol Pharmacol. 2016 May;94(5):563-9. doi: 10.1139/cjpp-2015-0194. Epub 2015 Nov 18.

PMID:
26771118
28.

Far-field effect in unipolar electrograms revisited: High-density mapping of atrial fibrillation in humans.

Podziemski P, Kuklik P, van Hunnik A, Zeemering S, Maesen B, Schotten U.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:5680-3. doi: 10.1109/EMBC.2015.7319681.

PMID:
26737581
29.

Slowed atrial and atrioventricular conduction and depressed HRV in a murine model of hypertrophic cardiomyopathy.

Lim WW, Baumert M, Neo M, Kuklik P, Ganesan AN, Lau DH, Tsoutsman T, Semsarian C, Sanders P, Saint DA.

Clin Exp Pharmacol Physiol. 2016 Jan;43(1):95-101. doi: 10.1111/1440-1681.12498.

PMID:
26444142
30.

High-density mapping of atrial fibrillation in a chronic substrate: evidence for distinct modes of repetitive wavefront propagation.

Kuklik P, Lau DH, Ganesan AN, Brooks AG, Sanders P.

Int J Cardiol. 2015 Nov 15;199:407-14. doi: 10.1016/j.ijcard.2015.07.057. Epub 2015 Jul 30.

PMID:
26253050
31.

Loss of Pace Capture on the Ablation Line During Pulmonary Vein Isolation versus "Dormant Conduction": Is Adenosine Expendable?

Schaeffer B, Willems S, Sultan A, Hoffmann BA, Lüker J, Schreiber D, Akbulak R, Moser J, Kuklik P, Steven D.

J Cardiovasc Electrophysiol. 2015 Oct;26(10):1075-80. doi: 10.1111/jce.12759. Epub 2015 Aug 29.

PMID:
26183341
32.

Reduction of Radiation Exposure in Atrial Fibrillation Ablation Using a New Image Integration Module: A Prospective Randomized Trial in Patients Undergoing Pulmonary Vein Isolation.

Akbulak RÖ, Schäffer B, Jularic M, Moser J, Schreiber D, Salzbrunn T, Meyer C, Eickholt C, Kuklik P, Hoffmann BA, Willems S.

J Cardiovasc Electrophysiol. 2015 Jul;26(7):747-53. doi: 10.1111/jce.12673. Epub 2015 May 25.

PMID:
25807878
33.

Indices of bipolar complex fractionated atrial electrograms correlate poorly with each other and atrial fibrillation substrate complexity.

Lau DH, Maesen B, Zeemering S, Kuklik P, van Hunnik A, Lankveld TA, Bidar E, Verheule S, Nijs J, Maessen J, Crijns H, Sanders P, Schotten U.

Heart Rhythm. 2015 Jul;12(7):1415-23. doi: 10.1016/j.hrthm.2015.03.017. Epub 2015 Mar 12.

PMID:
25771914
34.

Origin and characteristics of high Shannon entropy at the pivot of locally stable rotors: insights from computational simulation.

Ganesan AN, Kuklik P, Gharaviri A, Brooks A, Chapman D, Lau DH, Roberts-Thomson KC, Sanders P.

PLoS One. 2014 Nov 17;9(11):e110662. doi: 10.1371/journal.pone.0110662. eCollection 2014.

35.

Application of phase coherence in assessment of spatial alignment of electrodes during simultaneous endocardial-epicardial direct contact mapping of atrial fibrillation.

Kuklik P, Bidar E, Gharaviri A, Maessen J, Schotten U.

Europace. 2014 Nov;16 Suppl 4:iv135-iv140. doi: 10.1093/europace/euu247.

PMID:
25362164
36.

Reconstruction of instantaneous phase of unipolar atrial contact electrogram using a concept of sinusoidal recomposition and Hilbert transform.

Kuklik P, Zeemering S, Maesen B, Maessen J, Crijns HJ, Verheule S, Ganesan AN, Schotten U.

IEEE Trans Biomed Eng. 2015 Jan;62(1):296-302. doi: 10.1109/TBME.2014.2350029. Epub 2014 Aug 20.

PMID:
25148659
37.

Quantitative description of the 3D regional mechanics of the left atrium using cardiac magnetic resonance imaging.

Kuklik P, Molaee P, Podziemski P, Ganesan AN, Brooks AG, Worthley SG, Sanders P.

Physiol Meas. 2014 May;35(5):763-75. doi: 10.1088/0967-3334/35/5/763. Epub 2014 Mar 26.

PMID:
24671140
38.

Cardiovascular magnetic resonance of total and atrial pericardial adipose tissue: a validation study and development of a 3 dimensional pericardial adipose tissue model.

Mahajan R, Kuklik P, Grover S, Brooks AG, Wong CX, Sanders P, Selvanayagam JB.

J Cardiovasc Magn Reson. 2013 Aug 29;15:73. doi: 10.1186/1532-429X-15-73.

39.

High-density mapping of ventricular scar: a comparison of ventricular tachycardia (VT) supporting channels with channels that do not support VT.

Nayyar S, Wilson L, Ganesan AN, Sullivan T, Kuklik P, Chapman D, Brooks AG, Mahajan R, Baumert M, Young GD, Sanders P, Roberts-Thomson KC.

Circ Arrhythm Electrophysiol. 2014 Feb;7(1):90-8. doi: 10.1161/CIRCEP.113.000882. Epub 2014 Jan 1.

PMID:
24382409
40.

Catheter Ablation Targeting Complex Fractionated Atrial Electrogram in Atrial Fibrillation.

Lau DH, Zeemering S, Maesen B, Kuklik P, Verheule S, Schotten U.

J Atr Fibrillation. 2013 Oct 31;6(3):907. doi: 10.4022/jafib.907. eCollection 2013 Oct-Nov. Review.

41.

Atrial arrhythmia in ageing spontaneously hypertensive rats: unraveling the substrate in hypertension and ageing.

Lau DH, Shipp NJ, Kelly DJ, Thanigaimani S, Neo M, Kuklik P, Lim HS, Zhang Y, Drury K, Wong CX, Chia NH, Brooks AG, Dimitri H, Saint DA, Brown L, Sanders P.

PLoS One. 2013 Aug 27;8(8):e72416. doi: 10.1371/journal.pone.0072416. eCollection 2013.

42.

Myocardial infarction and atrial fibrillation: importance of atrial ischemia.

Alasady M, Shipp NJ, Brooks AG, Lim HS, Lau DH, Barlow D, Kuklik P, Worthley MI, Roberts-Thomson KC, Saint DA, Abhayaratna W, Sanders P.

Circ Arrhythm Electrophysiol. 2013 Aug;6(4):738-45. doi: 10.1161/CIRCEP.113.000163. Epub 2013 Jul 19.

PMID:
23873140
43.

Attraction and repulsion of spiral waves by inhomogeneity of conduction anisotropy--a model of spiral wave interaction with electrical remodeling of heart tissue.

Kuklik P, Sanders P, Szumowski L, Żebrowski JJ.

J Biol Phys. 2013 Jan;39(1):67-80. doi: 10.1007/s10867-012-9286-4. Epub 2012 Oct 7.

44.

Long-term outcomes of catheter ablation of atrial fibrillation: a systematic review and meta-analysis.

Ganesan AN, Shipp NJ, Brooks AG, Kuklik P, Lau DH, Lim HS, Sullivan T, Roberts-Thomson KC, Sanders P.

J Am Heart Assoc. 2013 Mar 18;2(2):e004549. doi: 10.1161/JAHA.112.004549. Review.

45.

Bipolar electrogram shannon entropy at sites of rotational activation: implications for ablation of atrial fibrillation.

Ganesan AN, Kuklik P, Lau DH, Brooks AG, Baumert M, Lim WW, Thanigaimani S, Nayyar S, Mahajan R, Kalman JM, Roberts-Thomson KC, Sanders P.

Circ Arrhythm Electrophysiol. 2013 Feb;6(1):48-57. doi: 10.1161/CIRCEP.112.976654. Epub 2012 Dec 23.

PMID:
23264437
46.

Obesity results in progressive atrial structural and electrical remodeling: implications for atrial fibrillation.

Abed HS, Samuel CS, Lau DH, Kelly DJ, Royce SG, Alasady M, Mahajan R, Kuklik P, Zhang Y, Brooks AG, Nelson AJ, Worthley SG, Abhayaratna WP, Kalman JM, Wittert GA, Sanders P.

Heart Rhythm. 2013 Jan;10(1):90-100. doi: 10.1016/j.hrthm.2012.08.043. Epub 2012 Sep 1.

PMID:
23063864
47.

Characteristics of ectopic triggers associated with paroxysmal and persistent atrial fibrillation: evidence for a changing role.

Brooks AG, Rangnekar G, Ganesan AN, Salna I, Middeldorp ME, Kuklik P, Baumert M, Roberts-Thomson KC, Sanders P.

Heart Rhythm. 2012 Sep;9(9):1367-74. doi: 10.1016/j.hrthm.2012.03.062. Epub 2012 Apr 3.

PMID:
22484650
48.

Direction-dependent conduction abnormalities in the chronically stretched atria.

Wong CX, John B, Brooks AG, Chandy ST, Kuklik P, Lau DH, Sullivan T, Roberts-Thomson KC, Sanders P.

Europace. 2012 Jul;14(7):954-61. doi: 10.1093/europace/eur428. Epub 2012 Feb 2.

PMID:
22308090
49.

Complex activity patterns in arterial wall: results from a model of calcium dynamics.

Buchner T, Pietkun J, Kuklik P.

Comput Biol Med. 2012 Mar;42(3):267-75. doi: 10.1016/j.compbiomed.2011.12.001. Epub 2011 Dec 26.

PMID:
22204868
50.

Atrial remodeling in obstructive sleep apnea: implications for atrial fibrillation.

Dimitri H, Ng M, Brooks AG, Kuklik P, Stiles MK, Lau DH, Antic N, Thornton A, Saint DA, McEvoy D, Antic R, Kalman JM, Sanders P.

Heart Rhythm. 2012 Mar;9(3):321-7. doi: 10.1016/j.hrthm.2011.10.017. Epub 2011 Oct 19.

PMID:
22016075

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