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Items: 18

1.

4-Methylumbelliferyl glucuronide contributes to hyaluronan synthesis inhibition.

Nagy N, Gurevich I, Kuipers HF, Ruppert SM, Marshall PL, Xie BJ, Sun W, Malkovskiy AV, Rajadas J, Grandoch M, Fischer JW, Frymoyer AR, Kaber G, Bollyky PL.

J Biol Chem. 2019 May 10;294(19):7864-7877. doi: 10.1074/jbc.RA118.006166. Epub 2019 Mar 26.

PMID:
30914479
2.

Hyaluronan in immune dysregulation and autoimmune diseases.

Nagy N, Kuipers HF, Marshall PL, Wang E, Kaber G, Bollyky PL.

Matrix Biol. 2019 May;78-79:292-313. doi: 10.1016/j.matbio.2018.03.022. Epub 2018 Apr 4. Review.

PMID:
29625181
3.

Phosphorylation of αB-crystallin supports reactive astrogliosis in demyelination.

Kuipers HF, Yoon J, van Horssen J, Han MH, Bollyky PL, Palmer TD, Steinman L.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1745-E1754. doi: 10.1073/pnas.1621314114. Epub 2017 Feb 14.

4.

The pharmacokinetics and dosing of oral 4-methylumbelliferone for inhibition of hyaluronan synthesis in mice.

Kuipers HF, Nagy N, Ruppert SM, Sunkari VG, Marshall PL, Gebe JA, Ishak HD, Keswani SG, Bollyky J, Frymoyer AR, Wight TN, Steinman L, Bollyky PL.

Clin Exp Immunol. 2016 Sep;185(3):372-81. doi: 10.1111/cei.12815.

5.

Hyaluronan synthesis is necessary for autoreactive T-cell trafficking, activation, and Th1 polarization.

Kuipers HF, Rieck M, Gurevich I, Nagy N, Butte MJ, Negrin RS, Wight TN, Steinman L, Bollyky PL.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1339-44. doi: 10.1073/pnas.1525086113. Epub 2016 Jan 19.

6.

Inhibition of hyaluronan synthesis restores immune tolerance during autoimmune insulitis.

Nagy N, Kaber G, Johnson PY, Gebe JA, Preisinger A, Falk BA, Sunkari VG, Gooden MD, Vernon RB, Bogdani M, Kuipers HF, Day AJ, Campbell DJ, Wight TN, Bollyky PL.

J Clin Invest. 2015 Oct 1;125(10):3928-40. doi: 10.1172/JCI79271. Epub 2015 Sep 14.

7.

4-methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer.

Nagy N, Kuipers HF, Frymoyer AR, Ishak HD, Bollyky JB, Wight TN, Bollyky PL.

Front Immunol. 2015 Mar 23;6:123. doi: 10.3389/fimmu.2015.00123. eCollection 2015. Review.

8.

Piet Mondrian's trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011.

Steinman L, Axtell RC, Barbieri D, Bhat R, Brownell SE, de Jong BA, Dunn SE, Grant JL, Han MH, Ho PP, Kuipers HF, Kurnellas MP, Ousman SS, Rothbard JB.

Mult Scler. 2013 Jan;19(1):5-14. doi: 10.1177/1352458512470730.

PMID:
23303879
9.

Reversal of paralysis and reduced inflammation from peripheral administration of β-amyloid in TH1 and TH17 versions of experimental autoimmune encephalomyelitis.

Grant JL, Ghosn EE, Axtell RC, Herges K, Kuipers HF, Woodling NS, Andreasson K, Herzenberg LA, Herzenberg LA, Steinman L.

Sci Transl Med. 2012 Aug 1;4(145):145ra105. doi: 10.1126/scitranslmed.3004145.

10.

Epigenetic control of CCR5 transcript levels in immune cells and modulation by small molecules inhibitors.

Wierda RJ, Kuipers HF, van Eggermond MC, Benard A, van Leeuwen JC, Carluccio S, Geutskens SB, Jukema JW, Marquez VE, Quax PH, van den Elsen PJ.

J Cell Mol Med. 2012 Aug;16(8):1866-77. doi: 10.1111/j.1582-4934.2011.01482.x.

11.

Statins amplify TLR-induced responses in microglia via inhibition of cholesterol biosynthesis.

Van Der Putten C, Kuipers HF, Zuiderwijk-Sick EA, Van Straalen L, Kondova I, Van Den Elsen PJ, Bajramovic JJ.

Glia. 2012 Jan;60(1):43-52. doi: 10.1002/glia.21245. Epub 2011 Sep 30.

PMID:
21964955
12.

CC chemokine receptor 5 gene promoter activation by the cyclic AMP response element binding transcription factor.

Kuipers HF, Biesta PJ, Montagne LJ, van Haastert ES, van der Valk P, van den Elsen PJ.

Blood. 2008 Sep 1;112(5):1610-9. doi: 10.1182/blood-2008-01-135111. Epub 2008 May 29.

13.

Immunomodulation by statins: inhibition of cholesterol vs. isoprenoid biosynthesis.

Kuipers HF, van den Elsen PJ.

Biomed Pharmacother. 2007 Aug;61(7):400-7. Epub 2007 Jul 5. Review.

PMID:
17643927
14.

Simvastatin affects cell motility and actin cytoskeleton distribution of microglia.

Kuipers HF, Rappert AA, Mommaas AM, van Haastert ES, van der Valk P, Boddeke HW, Biber KP, van den Elsen PJ.

Glia. 2006 Jan 15;53(2):115-23.

PMID:
16206159
15.

Statins affect cell-surface expression of major histocompatibility complex class II molecules by disrupting cholesterol-containing microdomains.

Kuipers HF, Biesta PJ, Groothuis TA, Neefjes JJ, Mommaas AM, van den Elsen PJ.

Hum Immunol. 2005 Jun;66(6):653-65.

PMID:
15993711
16.

Statins and control of MHC2TA gene transcription.

Kuipers HF, van den Elsen PJ.

Nat Med. 2005 Apr;11(4):365-6; author reply 366-7. No abstract available.

PMID:
15812506
17.

Transcriptional regulation of antigen presentation.

van den Elsen PJ, Holling TM, Kuipers HF, van der Stoep N.

Curr Opin Immunol. 2004 Feb;16(1):67-75. Review.

PMID:
14734112
18.

CX3CL1 and CX3CR1 expression in human brain tissue: noninflammatory control versus multiple sclerosis.

Hulshof S, van Haastert ES, Kuipers HF, van den Elsen PJ, De Groot CJ, van der Valk P, Ravid R, Biber K.

J Neuropathol Exp Neurol. 2003 Sep;62(9):899-907.

PMID:
14533779

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