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Items: 1 to 50 of 420

1.

The Origin of Follicular Bile Acids in the Human Ovary.

Nagy RA, Hollema H, Andrei D, Jurdzinski A, Kuipers F, Hoek A, Tietge UJF.

Am J Pathol. 2019 Jul 29. pii: S0002-9440(19)30652-2. doi: 10.1016/j.ajpath.2019.06.011. [Epub ahead of print]

PMID:
31369754
2.

Autoantibodies to Apolipoprotein A-1 as Independent Predictors of Cardiovascular Mortality in Renal Transplant Recipients.

Anderson JLC, Pagano S, Virzi J, Dullaart RPF, Annema W, Kuipers F, Bakker SJL, Vuilleumier N, Tietge UJF.

J Clin Med. 2019 Jun 29;8(7). pii: E948. doi: 10.3390/jcm8070948.

3.

Farnesoid X Receptor alters adipose tissue architecture in mice and limits storage capacity leading to metabolic derangements.

van Zutphen T, Stroeve JHM, Yang J, Bloks VW, Jurdzinski A, Roelofsen H, Huijkman NCA, van Dijk TH, Vonk RJ, van Deursen J, Staels B, Groen AK, Kuipers F.

J Lipid Res. 2019 Jun 28. pii: jlr.M094508. doi: 10.1194/jlr.M094508. [Epub ahead of print]

4.

Potential of Intestine-Selective FXR Modulation for Treatment of Metabolic Disease.

van Zutphen T, Bertolini A, de Vries HD, Bloks VW, de Boer JF, Jonker JW, Kuipers F.

Handb Exp Pharmacol. 2019 Jun 25. doi: 10.1007/164_2019_233. [Epub ahead of print]

PMID:
31236687
5.

The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance.

Wijers M, Zanoni P, Liv N, Vos DY, Jäckstein MY, Smit M, Wilbrink S, Wolters JC, van der Veen YT, Huijkman N, Dekker D, Kloosterhuis N, van Dijk TH, Billadeau DD, Kuipers F, Klumperman J, von Eckardstein A, Kuivenhoven JA, van de Sluis B.

JCI Insight. 2019 Jun 6;4(11). pii: 126462. doi: 10.1172/jci.insight.126462. eCollection 2019 Jun 6.

6.

Blocking Sodium-Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice.

Roscam Abbing RLP, Slijepcevic D, Donkers JM, Havinga R, Duijst S, Paulusma CC, Kuiper J, Kuipers F, Groen AK, Oude Elferink RPJ, van de Graaf SFJ.

Hepatology. 2019 May 28. doi: 10.1002/hep.30792. [Epub ahead of print]

PMID:
31136002
7.

Glucose-6-Phosphate Regulates Hepatic Bile Acid Synthesis in Mice.

Hoogerland JA, Lei Y, Wolters JC, de Boer JF, Bos T, Bleeker A, Mulder NL, van Dijk TH, Kuivenhoven JA, Rajas F, Mithieux G, Haeusler RA, Verkade HJ, Bloks VW, Kuipers F, Oosterveer MH.

Hepatology. 2019 May 18. doi: 10.1002/hep.30778. [Epub ahead of print]

PMID:
31102537
8.

Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk.

Kurilshikov A, van den Munckhof ICL, Chen L, Bonder MJ, Schraa K, Rutten JHW, Riksen NP, de Graaf J, Oosting M, Sanna S, Joosten LAB, van der Graaf M, Brand T, Koonen DPY, van Faassen M; LifeLines DEEP Cohort Study, BBMRI Metabolomics Consortium, Slagboom PE, Xavier RJ, Kuipers F, Hofker MH, Wijmenga C, Netea MG, Zhernakova A, Fu J.

Circ Res. 2019 Jun 7;124(12):1808-1820. doi: 10.1161/CIRCRESAHA.118.314642. Epub 2019 Apr 11.

PMID:
30971183
9.

Targeting senescent cells alleviates obesity-induced metabolic dysfunction.

Palmer AK, Xu M, Zhu Y, Pirtskhalava T, Weivoda MM, Hachfeld CM, Prata LG, van Dijk TH, Verkade E, Casaclang-Verzosa G, Johnson KO, Cubro H, Doornebal EJ, Ogrodnik M, Jurk D, Jensen MD, Chini EN, Miller JD, Matveyenko A, Stout MB, Schafer MJ, White TA, Hickson LJ, Demaria M, Garovic V, Grande J, Arriaga EA, Kuipers F, von Zglinicki T, LeBrasseur NK, Campisi J, Tchkonia T, Kirkland JL.

Aging Cell. 2019 Jun;18(3):e12950. doi: 10.1111/acel.12950. Epub 2019 Mar 25.

10.

Impaired Hepatic Phosphatidylcholine Synthesis Leads to Cholestasis in Mice Challenged With a High-Fat Diet.

Wan S, Kuipers F, Havinga R, Ando H, Vance DE, Jacobs RL, van der Veen JN.

Hepatol Commun. 2019 Jan 2;3(2):262-276. doi: 10.1002/hep4.1302. eCollection 2019 Feb.

11.

A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis.

Brandsma E, Kloosterhuis NJ, Koster M, Dekker DC, Gijbels MJJ, van der Velden S, Ríos-Morales M, van Faassen MJR, Loreti MG, de Bruin A, Fu J, Kuipers F, Bakker BM, Westerterp M, de Winther MPJ, Hofker MH, van de Sluis B, Koonen DPY.

Circ Res. 2019 Jan 4;124(1):94-100. doi: 10.1161/CIRCRESAHA.118.313234.

12.

Author Correction: Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome.

Zhernakova DV, Le TH, Kurilshikov A, Atanasovska B, Bonder MJ, Sanna S, Claringbould A, Võsa U, Deelen P, Franke L, de Boer RA, Kuipers F, Netea MG, Hofker MH, Wijmenga C, Zhernakova A, Fu J; LifeLines cohort study; BIOS consortium.

Nat Genet. 2018 Dec;50(12):1752. doi: 10.1038/s41588-018-0275-9.

PMID:
30341443
13.

Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome.

Zhernakova DV, Le TH, Kurilshikov A, Atanasovska B, Bonder MJ, Sanna S, Claringbould A, Võsa U, Deelen P, Franke L, de Boer RA, Kuipers F, Netea MG, Hofker MH, Wijmenga C, Zhernakova A, Fu J; LifeLines cohort study; BIOS consortium.

Nat Genet. 2018 Nov;50(11):1524-1532. doi: 10.1038/s41588-018-0224-7. Epub 2018 Sep 24. Erratum in: Nat Genet. 2018 Oct 19;:.

14.

Intestinal de novo phosphatidylcholine synthesis is required for dietary lipid absorption and metabolic homeostasis.

Kennelly JP, van der Veen JN, Nelson RC, Leonard KA, Havinga R, Buteau J, Kuipers F, Jacobs RL.

J Lipid Res. 2018 Sep;59(9):1695-1708. doi: 10.1194/jlr.M087056. Epub 2018 Jul 14.

PMID:
30007917
15.

Pharmacomicrobiomics: a novel route towards personalized medicine?

Doestzada M, Vila AV, Zhernakova A, Koonen DPY, Weersma RK, Touw DJ, Kuipers F, Wijmenga C, Fu J.

Protein Cell. 2018 May;9(5):432-445. doi: 10.1007/s13238-018-0547-2. Epub 2018 Apr 28. Review.

16.

New insights in the multiple roles of bile acids and their signaling pathways in metabolic control.

de Boer JF, Bloks VW, Verkade E, Heiner-Fokkema MR, Kuipers F.

Curr Opin Lipidol. 2018 Jun;29(3):194-202. doi: 10.1097/MOL.0000000000000508.

PMID:
29553998
17.

Cholesterol Transport Revisited: A New Turbo Mechanism to Drive Cholesterol Excretion.

de Boer JF, Kuipers F, Groen AK.

Trends Endocrinol Metab. 2018 Feb;29(2):123-133. doi: 10.1016/j.tem.2017.11.006. Epub 2017 Dec 21. Review.

PMID:
29276134
18.

The art of quantifying glucose metabolism.

van Dijk TH, Reijngoud D, Kuipers F.

Am J Physiol Endocrinol Metab. 2017 Aug 1;313(2):E257-E258. doi: 10.1152/ajpendo.00066.2017. No abstract available.

19.

ANGPTL4 promotes bile acid absorption during taurocholic acid supplementation via a mechanism dependent on the gut microbiota.

Janssen AWF, Dijk W, Boekhorst J, Kuipers F, Groen AK, Lukovac S, Hooiveld GJEJ, Kersten S.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Oct;1862(10 Pt A):1056-1067. doi: 10.1016/j.bbalip.2017.07.005. Epub 2017 Jul 18.

PMID:
28733267
20.

An unexpected role for bile acid synthesis in adaptation to low temperature.

Kuipers F, Groen AK.

Nat Med. 2017 Jul 11;23(7):800-802. doi: 10.1038/nm.4365. No abstract available.

PMID:
28697185
21.

Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids.

Janssen AWF, Houben T, Katiraei S, Dijk W, Boutens L, van der Bolt N, Wang Z, Brown JM, Hazen SL, Mandard S, Shiri-Sverdlov R, Kuipers F, Willems van Dijk K, Vervoort J, Stienstra R, Hooiveld GJEJ, Kersten S.

J Lipid Res. 2017 Jul;58(7):1399-1416. doi: 10.1194/jlr.M075713. Epub 2017 May 22.

22.

Transintestinal and Biliary Cholesterol Secretion Both Contribute to Macrophage Reverse Cholesterol Transport in Rats-Brief Report.

de Boer JF, Schonewille M, Dikkers A, Koehorst M, Havinga R, Kuipers F, Tietge UJ, Groen AK.

Arterioscler Thromb Vasc Biol. 2017 Apr;37(4):643-646. doi: 10.1161/ATVBAHA.116.308558. Epub 2017 Feb 23.

PMID:
28232326
23.

Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice.

de Boer JF, Schonewille M, Boesjes M, Wolters H, Bloks VW, Bos T, van Dijk TH, Jurdzinski A, Boverhof R, Wolters JC, Kuivenhoven JA, van Deursen JM, Oude Elferink RPJ, Moschetta A, Kremoser C, Verkade HJ, Kuipers F, Groen AK.

Gastroenterology. 2017 Apr;152(5):1126-1138.e6. doi: 10.1053/j.gastro.2016.12.037. Epub 2017 Jan 5.

PMID:
28065787
24.

Optimization problems in correlated networks.

Yang S, Trajanovski S, Kuipers FA.

Comput Soc Netw. 2016;3(1):1. doi: 10.1186/s40649-016-0026-y. Epub 2016 Jan 22.

25.

Nutrient Status Assessment in Individuals and Populations for Healthy Aging-Statement from an Expert Workshop.

Péter S, Saris WH, Mathers JC, Feskens E, Schols A, Navis G, Kuipers F, Weber P, Eggersdorfer M.

Nutrients. 2015 Dec 16;7(12):10491-500. doi: 10.3390/nu7125547. Review.

26.

Reply to: "Impaired expression of multidrug resistance-associated protein 2 and liver damage in erythropoietic protoporphyria".

Bloks VW, Plösch T, Jonker JW, Kuipers F.

Hepatology. 2016 May;63(5):1743-4. doi: 10.1002/hep.27993. Epub 2015 Aug 21. No abstract available.

PMID:
26173575
27.

Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4.

Out C, Patankar JV, Doktorova M, Boesjes M, Bos T, de Boer S, Havinga R, Wolters H, Boverhof R, van Dijk TH, Smoczek A, Bleich A, Sachdev V, Kratky D, Kuipers F, Verkade HJ, Groen AK.

J Hepatol. 2015 Sep;63(3):697-704. doi: 10.1016/j.jhep.2015.04.030. Epub 2015 May 27.

28.

Selected nutrients and their implications for health and disease across the lifespan: a roadmap.

Péter S, Eggersdorfer M, van Asselt D, Buskens E, Detzel P, Freijer K, Koletzko B, Kraemer K, Kuipers F, Neufeld L, Obeid R, Wieser S, Zittermann A, Weber P.

Nutrients. 2014 Dec 22;6(12):6076-94. doi: 10.3390/nu6126076.

29.

Hepatic farnesoid X-receptor isoforms α2 and α4 differentially modulate bile salt and lipoprotein metabolism in mice.

Boesjes M, Bloks VW, Hageman J, Bos T, van Dijk TH, Havinga R, Wolters H, Jonker JW, Kuipers F, Groen AK.

PLoS One. 2014 Dec 15;9(12):e115028. doi: 10.1371/journal.pone.0115028. eCollection 2014.

30.

A systems biology approach reveals the physiological origin of hepatic steatosis induced by liver X receptor activation.

Hijmans BS, Tiemann CA, Grefhorst A, Boesjes M, van Dijk TH, Tietge UJ, Kuipers F, van Riel NA, Groen AK, Oosterveer MH.

FASEB J. 2015 Apr;29(4):1153-64. doi: 10.1096/fj.14-254656. Epub 2014 Dec 4.

PMID:
25477282
31.

New insights in the biology of ABC transporters ABCC2 and ABCC3: impact on drug disposition.

van der Schoor LW, Verkade HJ, Kuipers F, Jonker JW.

Expert Opin Drug Metab Toxicol. 2015 Feb;11(2):273-93. doi: 10.1517/17425255.2015.981152. Epub 2014 Nov 7. Review.

PMID:
25380746
32.

Domination-time dynamics in susceptible-infected-susceptible virus competition on networks.

van de Bovenkamp R, Kuipers F, Van Mieghem P.

Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Apr;89(4):042818. Epub 2014 Apr 29.

PMID:
24827304
33.

Beyond intestinal soap--bile acids in metabolic control.

Kuipers F, Bloks VW, Groen AK.

Nat Rev Endocrinol. 2014 Aug;10(8):488-98. doi: 10.1038/nrendo.2014.60. Epub 2014 May 13. Review.

PMID:
24821328
34.

FXR: the key to benefits in bariatric surgery?

Kuipers F, Groen AK.

Nat Med. 2014 Apr;20(4):337-8. doi: 10.1038/nm.3525. No abstract available.

PMID:
24710375
35.

Prednisolone increases enterohepatic cycling of bile acids by induction of Asbt and promotes reverse cholesterol transport.

Out C, Dikkers A, Laskewitz A, Boverhof R, van der Ley C, Kema IP, Wolters H, Havinga R, Verkade HJ, Kuipers F, Tietge UJ, Groen AK.

J Hepatol. 2014 Aug;61(2):351-7. doi: 10.1016/j.jhep.2014.03.025. Epub 2014 Mar 26.

PMID:
24681341
36.

Cross-talk between liver and intestine in control of cholesterol and energy homeostasis.

Groen AK, Bloks VW, Verkade H, Kuipers F.

Mol Aspects Med. 2014 Jun;37:77-88. doi: 10.1016/j.mam.2014.02.001. Epub 2014 Feb 18. Review.

PMID:
24560594
37.

Impaired amino acid metabolism contributes to fasting-induced hypoglycemia in fatty acid oxidation defects.

Houten SM, Herrema H, Te Brinke H, Denis S, Ruiter JP, van Dijk TH, Argmann CA, Ottenhoff R, Müller M, Groen AK, Kuipers F, Reijngoud DJ, Wanders RJ.

Hum Mol Genet. 2013 Dec 20;22(25):5249-61. doi: 10.1093/hmg/ddt382. Epub 2013 Aug 9.

PMID:
23933733
38.

Bile acid look-alike controls life span in C. elegans.

Groen AK, Kuipers F.

Cell Metab. 2013 Aug 6;18(2):151-2. doi: 10.1016/j.cmet.2013.07.009.

39.

Farnesoid X receptor activation increases cholesteryl ester transfer protein expression in humans and transgenic mice.

Gautier T, de Haan W, Grober J, Ye D, Bahr MJ, Claudel T, Nijstad N, Van Berkel TJ, Havekes LM, Manns MP, Willems SM, Hogendoorn PC, Lagrost L, Kuipers F, Van Eck M, Rensen PC, Tietge UJ.

J Lipid Res. 2013 Aug;54(8):2195-205. doi: 10.1194/jlr.M038141. Epub 2013 Apr 25.

40.

Bile acid sequestration normalizes plasma cholesterol and reduces atherosclerosis in hypercholesterolemic mice. No additional effect of physical activity.

Meissner M, Wolters H, de Boer RA, Havinga R, Boverhof R, Bloks VW, Kuipers F, Groen AK.

Atherosclerosis. 2013 May;228(1):117-23. doi: 10.1016/j.atherosclerosis.2013.02.021. Epub 2013 Feb 26.

41.

A novel approach to monitor glucose metabolism using stable isotopically labelled glucose in longitudinal studies in mice.

van Dijk TH, Laskewitz AJ, Grefhorst A, Boer TS, Bloks VW, Kuipers F, Groen AK, Reijngoud DJ.

Lab Anim. 2013 Apr;47(2):79-88. doi: 10.1177/0023677212473714. Epub 2013 Mar 14.

PMID:
23492513
42.

Bile acids and cholestasis.

Out C, Kuipers F, Groen AK.

Gastroenterology. 2013 Feb;144(2):e17-8. doi: 10.1053/j.gastro.2012.10.053. Epub 2012 Dec 21. No abstract available.

PMID:
23261889
43.

Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index.

van Lierop MJ, Alkema W, Laskewitz AJ, Dijkema R, van der Maaden HM, Smit MJ, Plate R, Conti PG, Jans CG, Timmers CM, van Boeckel CA, Lusher SJ, McGuire R, van Schaik RC, de Vlieg J, Smeets RL, Hofstra CL, Boots AM, van Duin M, Ingelse BA, Schoonen WG, Grefhorst A, van Dijk TH, Kuipers F, Dokter WH.

PLoS One. 2012;7(11):e48385. doi: 10.1371/journal.pone.0048385. Epub 2012 Nov 12.

44.

Stimulation of murine biliary cholesterol secretion by thyroid hormone is dependent on a functional ABCG5/G8 complex.

Bonde Y, Plösch T, Kuipers F, Angelin B, Rudling M.

Hepatology. 2012 Nov;56(5):1828-37. doi: 10.1002/hep.25861. Epub 2012 Oct 14.

45.

Chronic prednisolone treatment aggravates hyperglycemia in mice fed a high-fat diet but does not worsen dietary fat-induced insulin resistance.

Laskewitz AJ, van Dijk TH, Grefhorst A, van Lierop MJ, Schreurs M, Bloks VW, Reijngoud DJ, Dokter WH, Kuipers F, Groen AK.

Endocrinology. 2012 Aug;153(8):3713-23. doi: 10.1210/en.2011-1891. Epub 2012 May 31.

PMID:
22653558
46.

The human hepatocyte cell lines IHH and HepaRG: models to study glucose, lipid and lipoprotein metabolism.

Samanez CH, Caron S, Briand O, Dehondt H, Duplan I, Kuipers F, Hennuyer N, Clavey V, Staels B.

Arch Physiol Biochem. 2012 Jul;118(3):102-11. doi: 10.3109/13813455.2012.683442. Epub 2012 May 18.

PMID:
22594799
47.

Pharmacological LXR activation reduces presence of SR-B1 in liver membranes contributing to LXR-mediated induction of HDL-cholesterol.

Grefhorst A, Oosterveer MH, Brufau G, Boesjes M, Kuipers F, Groen AK.

Atherosclerosis. 2012 Jun;222(2):382-9. doi: 10.1016/j.atherosclerosis.2012.02.014. Epub 2012 Mar 3.

48.

Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function.

Oosterveer MH, Koolman AH, de Boer PT, Bos T, Bleeker A, van Dijk TH, Bloks VW, Kuipers F, Sauer PJ, van Dijk G.

Nutr Metab (Lond). 2011 Dec 27;8:93. doi: 10.1186/1743-7075-8-93.

49.

Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice.

de Boer JF, Annema W, Schreurs M, van der Veen JN, van der Giet M, Nijstad N, Kuipers F, Tietge UJ.

J Lipid Res. 2012 Mar;53(3):348-57. doi: 10.1194/jlr.M018671. Epub 2011 Dec 18.

50.

Treatment with high-dose simvastatin inhibits geranylgeranylation in AML blast cells in a subset of AML patients.

van der Weide K, de Jonge-Peeters S, Huls G, Fehrmann RS, Schuringa JJ, Kuipers F, de Vries EG, Vellenga E.

Exp Hematol. 2012 Mar;40(3):177-186.e6. doi: 10.1016/j.exphem.2011.11.008. Epub 2011 Nov 25.

PMID:
22120639

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