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Items: 8


PTPN22 inhibition resets defective human central B cell tolerance.

Schickel JN, Kuhny M, Baldo A, Bannock JM, Massad C, Wang H, Katz N, Oe T, Menard L, Soulas-Sprauel P, Strowig T, Flavell R, Meffre E.

Sci Immunol. 2016;1(1). pii: aaf7153. Epub 2016 Jul 22.


CD39 is a negative regulator of P2X7-mediated inflammatory cell death in mast cells.

Kuhny M, Hochdörfer T, Ayata CK, Idzko M, Huber M.

Cell Commun Signal. 2014 Jul 16;12:40. doi: 10.1186/s12964-014-0040-3.


Regulation of FcεRI signaling by lipid phosphatases.

Kuhny M, Zorn CN, Huber M.

Curr Top Microbiol Immunol. 2014;382:111-27. doi: 10.1007/978-3-319-07911-0_6. Review.


Secretory lysosomes of mouse mast cells store and exocytose active caspase-3 in a strictly granzyme B dependent manner.

Zorn CN, Pardo J, Martin P, Kuhny M, Simon MM, Huber M.

Eur J Immunol. 2013 Dec;43(12):3209-18. doi: 10.1002/eji.201343941.


The 1,4-benzodiazepine Ro5-4864 (4-chlorodiazepam) suppresses multiple pro-inflammatory mast cell effector functions.

Yousefi OS, Wilhelm T, Maschke-Neuß K, Kuhny M, Martin C, Molderings GJ, Kratz F, Hildenbrand B, Huber M.

Cell Commun Signal. 2013 Feb 20;11(1):13. doi: 10.1186/1478-811X-11-13.


Activation of the PI3K pathway increases TLR-induced TNF-α and IL-6 but reduces IL-1β production in mast cells.

Hochdörfer T, Kuhny M, Zorn CN, Hendriks RW, Vanhaesebroeck B, Bohnacker T, Krystal G, Huber M.

Cell Signal. 2011 May;23(5):866-75. doi: 10.1016/j.cellsig.2011.01.012. Epub 2011 Jan 22.


Steel factor enhances supraoptimal antigen-induced IL-6 production from mast cells via activation of protein kinase C-beta.

Fehrenbach K, Lessmann E, Zorn CN, Kuhny M, Grochowy G, Krystal G, Leitges M, Huber M.

J Immunol. 2009 Jun 15;182(12):7897-905. doi: 10.4049/jimmunol.0801773.


Requirement for CD45 in fine-tuning mast cell responses mediated by different ligand-receptor systems.

Grochowy G, Hermiston ML, Kuhny M, Weiss A, Huber M.

Cell Signal. 2009 Aug;21(8):1277-86. doi: 10.1016/j.cellsig.2009.03.018. Epub 2009 Mar 27.


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