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Items: 1 to 50 of 56

1.

Oat bran, but not its isolated bioactive β-glucans or polyphenols, have a bifidogenic effect in an in vitro fermentation model of the gut microbiota.

Kristek A, Wiese M, Heuer P, Kosik O, Schär MY, Soycan G, Alsharif S, Kuhnle GGC, Walton G, Spencer JPE.

Br J Nutr. 2019 Jan 28:1-11. doi: 10.1017/S0007114518003501. [Epub ahead of print]

PMID:
30688188
2.

Stable Isotope Ratios: Nutritional Biomarker and More.

Kuhnle GGC.

J Nutr. 2018 Dec 1;148(12):1883-1885. doi: 10.1093/jn/nxy247. No abstract available.

PMID:
30517730
3.

Dietary Intervention Modifies DNA Methylation Age Assessed by the Epigenetic Clock.

Sae-Lee C, Corsi S, Barrow TM, Kuhnle GGC, Bollati V, Mathers JC, Byun HM.

Mol Nutr Food Res. 2018 Dec;62(23):e1800092. doi: 10.1002/mnfr.201800092. Epub 2018 Nov 2.

PMID:
30350398
4.

Evaluation at scale of microbiome-derived metabolites as biomarker of flavan-3-ol intake in epidemiological studies.

Ottaviani JI, Fong R, Kimball J, Ensunsa JL, Britten A, Lucarelli D, Luben R, Grace PB, Mawson DH, Tym A, Wierzbicki A, Khaw KT, Schroeter H, Kuhnle GGC.

Sci Rep. 2018 Jun 29;8(1):9859. doi: 10.1038/s41598-018-28333-w.

5.

Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption.

Martin OCB, Naud N, Taché S, Debrauwer L, Chevolleau S, Dupuy J, Chantelauze C, Durand D, Pujos-Guillot E, Blas-Y-Estrada F, Urbano C, Kuhnle GGC, Santé-Lhoutellier V, Sayd T, Viala D, Blot A, Meunier N, Schlich P, Attaix D, Guéraud F, Scislowski V, Corpet DE, Pierre FHF.

Cancer Prev Res (Phila). 2018 Sep;11(9):569-580. doi: 10.1158/1940-6207.CAPR-17-0361. Epub 2018 Jun 28.

PMID:
29954759
6.

Nutrition epidemiology of flavan-3-ols: The known unknowns.

Kuhnle GGC.

Mol Aspects Med. 2018 Jun;61:2-11. doi: 10.1016/j.mam.2017.10.003. Epub 2017 Nov 16. Review.

7.

Association between urinary biomarkers of total sugars intake and measures of obesity in a cross-sectional study.

Campbell R, Tasevska N, Jackson KG, Sagi-Kiss V, di Paolo N, Mindell JS, Lister SJ, Khaw KT, Kuhnle GGC.

PLoS One. 2017 Jul 19;12(7):e0179508. doi: 10.1371/journal.pone.0179508. eCollection 2017.

8.

Sulfate, nitrate and blood pressure - An EPIC interaction between sulfur and nitrogen.

Kuhnle GG, Luben R, Khaw KT, Feelisch M.

Pharmacol Res. 2017 Aug;122:127-129. doi: 10.1016/j.phrs.2017.06.006. Epub 2017 Jun 10. Review.

9.

The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine.

Cortese-Krott MM, Koning A, Kuhnle GGC, Nagy P, Bianco CL, Pasch A, Wink DA, Fukuto JM, Jackson AA, van Goor H, Olson KR, Feelisch M.

Antioxid Redox Signal. 2017 Oct 1;27(10):684-712. doi: 10.1089/ars.2017.7083. Epub 2017 Jun 6. Review.

10.

Red Wine and Pomegranate Extracts Suppress Cured Meat Promotion of Colonic Mucin-Depleted Foci in Carcinogen-Induced Rats.

Bastide NM, Naud N, Nassy G, Vendeuvre JL, Taché S, Guéraud F, Hobbs DA, Kuhnle GG, Corpet DE, Pierre FH.

Nutr Cancer. 2017 Feb-Mar;69(2):289-298. doi: 10.1080/01635581.2017.1263745. Epub 2017 Jan 17.

PMID:
28094544
11.

Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study.

Velmurugan S, Gan JM, Rathod KS, Khambata RS, Ghosh SM, Hartley A, Van Eijl S, Sagi-Kiss V, Chowdhury TA, Curtis M, Kuhnle GG, Wade WG, Ahluwalia A.

Am J Clin Nutr. 2016 Jan;103(1):25-38. doi: 10.3945/ajcn.115.116244. Epub 2015 Nov 25.

12.

Cocoa flavanol intake improves endothelial function and Framingham Risk Score in healthy men and women: a randomised, controlled, double-masked trial: the Flaviola Health Study.

Sansone R, Rodriguez-Mateos A, Heuel J, Falk D, Schuler D, Wagstaff R, Kuhnle GG, Spencer JP, Schroeter H, Merx MW, Kelm M, Heiss C; Flaviola Consortium, European Union 7th Framework Program.

Br J Nutr. 2015 Oct 28;114(8):1246-55. doi: 10.1017/S0007114515002822. Epub 2015 Sep 9.

13.

Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl.

Cortese-Krott MM, Kuhnle GG, Dyson A, Fernandez BO, Grman M, DuMond JF, Barrow MP, McLeod G, Nakagawa H, Ondrias K, Nagy P, King SB, Saavedra JE, Keefer LK, Singer M, Kelm M, Butler AR, Feelisch M.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):E4651-60. doi: 10.1073/pnas.1509277112. Epub 2015 Jul 29.

14.

Impact of cocoa flavanol intake on age-dependent vascular stiffness in healthy men: a randomized, controlled, double-masked trial.

Heiss C, Sansone R, Karimi H, Krabbe M, Schuler D, Rodriguez-Mateos A, Kraemer T, Cortese-Krott MM, Kuhnle GG, Spencer JP, Schroeter H, Merx MW, Kelm M; FLAVIOLA Consortium, European Union 7th Framework Program.

Age (Dordr). 2015 Jun;37(3):9794. doi: 10.1007/s11357-015-9794-9. Epub 2015 May 27.

15.

Flavonoid intake in European adults (18 to 64 years).

Vogiatzoglou A, Mulligan AA, Lentjes MA, Luben RN, Spencer JP, Schroeter H, Khaw KT, Kuhnle GG.

PLoS One. 2015 May 26;10(5):e0128132. doi: 10.1371/journal.pone.0128132. eCollection 2015.

16.

Associations between flavan-3-ol intake and CVD risk in the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk).

Vogiatzoglou A, Mulligan AA, Bhaniani A, Lentjes MAH, McTaggart A, Luben RN, Heiss C, Kelm M, Merx MW, Spencer JPE, Schroeter H, Khaw KT, Kuhnle GGC.

Free Radic Biol Med. 2015 Jul;84:1-10. doi: 10.1016/j.freeradbiomed.2015.03.005. Epub 2015 Mar 17.

17.

Reply to KJ Petzke.

Forouhi NG, Kuhnle GG, Patel PS, O'Connell TC.

Am J Clin Nutr. 2015 Mar;101(3):688. doi: 10.3945/ajcn.114.103309. No abstract available.

PMID:
25733658
18.

Association between sucrose intake and risk of overweight and obesity in a prospective sub-cohort of the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk).

Kuhnle GG, Tasevska N, Lentjes MA, Griffin JL, Sims MA, Richardson L, Aspinall SM, Mulligan AA, Luben RN, Khaw KT.

Public Health Nutr. 2015 Oct;18(15):2815-24. doi: 10.1017/S1368980015000300. Epub 2015 Feb 23.

19.

A central role for heme iron in colon carcinogenesis associated with red meat intake.

Bastide NM, Chenni F, Audebert M, Santarelli RL, Taché S, Naud N, Baradat M, Jouanin I, Surya R, Hobbs DA, Kuhnle GG, Raymond-Letron I, Gueraud F, Corpet DE, Pierre FH.

Cancer Res. 2015 Mar 1;75(5):870-9. doi: 10.1158/0008-5472.CAN-14-2554. Epub 2015 Jan 15.

20.

Serum carbon and nitrogen stable isotopes as potential biomarkers of dietary intake and their relation with incident type 2 diabetes: the EPIC-Norfolk study.

Patel PS, Cooper AJ, O'Connell TC, Kuhnle GG, Kneale CK, Mulligan AM, Luben RN, Brage S, Khaw KT, Wareham NJ, Forouhi NG.

Am J Clin Nutr. 2014 Aug;100(2):708-18. doi: 10.3945/ajcn.113.068577. Epub 2014 Jul 2.

21.

O⁶-carboxymethylguanine DNA adduct formation and lipid peroxidation upon in vitro gastrointestinal digestion of haem-rich meat.

Vanden Bussche J, Hemeryck LY, Van Hecke T, Kuhnle GG, Pasmans F, Moore SA, Van de Wiele T, De Smet S, Vanhaecke L.

Mol Nutr Food Res. 2014 Sep;58(9):1883-96. doi: 10.1002/mnfr.201400078. Epub 2014 Jul 2.

PMID:
24990219
22.

Assessment of the dietary intake of total flavan-3-ols, monomeric flavan-3-ols, proanthocyanidins and theaflavins in the European Union.

Vogiatzoglou A, Mulligan AA, Luben RN, Lentjes MA, Heiss C, Kelm M, Merx MW, Spencer JP, Schroeter H, Kuhnle GG.

Br J Nutr. 2014 Apr 28;111(8):1463-73. doi: 10.1017/S0007114513003930. Epub 2013 Dec 13.

PMID:
24331295
23.

Estimated dietary intakes and sources of flavanols in the German population (German National Nutrition Survey II).

Vogiatzoglou A, Heuer T, Mulligan AA, Lentjes MA, Luben RN, Kuhnle GG.

Eur J Nutr. 2014;53(2):635-43. doi: 10.1007/s00394-013-0572-0. Epub 2013 Aug 6.

PMID:
23917449
24.

The diet-body offset in human nitrogen isotopic values: a controlled dietary study.

O'Connell TC, Kneale CJ, Tasevska N, Kuhnle GG.

Am J Phys Anthropol. 2012 Nov;149(3):426-34. doi: 10.1002/ajpa.22140. Epub 2012 Oct 5.

25.

A multilevel analytical approach for detection and visualization of intracellular NO production and nitrosation events using diaminofluoresceins.

Cortese-Krott MM, Rodriguez-Mateos A, Kuhnle GG, Brown G, Feelisch M, Kelm M.

Free Radic Biol Med. 2012 Dec 1;53(11):2146-58. doi: 10.1016/j.freeradbiomed.2012.09.008. Epub 2012 Sep 28.

PMID:
23026413
26.

Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease.

Cortese-Krott MM, Rodriguez-Mateos A, Sansone R, Kuhnle GG, Thasian-Sivarajah S, Krenz T, Horn P, Krisp C, Wolters D, Heiß C, Kröncke KD, Hogg N, Feelisch M, Kelm M.

Blood. 2012 Nov 15;120(20):4229-37. doi: 10.1182/blood-2012-07-442277. Epub 2012 Sep 24.

27.

Intakes and sources of isoflavones, lignans, enterolignans, coumestrol and soya-containing foods in the Norfolk arm of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk), from 7 d food diaries, using a newly updated database.

Mulligan AA, Kuhnle GG, Lentjes MA, van Scheltinga V, Powell NA, McTaggart A, Bhaniani A, Khaw KT.

Public Health Nutr. 2013 Aug;16(8):1454-62. doi: 10.1017/S1368980012003904. Epub 2012 Sep 3.

PMID:
22939391
28.

An approach based on ultra-high pressure liquid chromatography-tandem mass spectrometry to quantify O6-methyl and O6-carboxymethylguanine DNA adducts in intestinal cell lines.

Vanden Bussche J, Moore SA, Pasmans F, Kuhnle GG, Vanhaecke L.

J Chromatogr A. 2012 Sep 28;1257:25-33. doi: 10.1016/j.chroma.2012.07.040. Epub 2012 Jul 20.

PMID:
22921361
29.

Dietary, lifestyle and clinicopathological factors associated with APC mutations and promoter methylation in colorectal cancers from the EPIC-Norfolk study.

Gay LJ, Mitrou PN, Keen J, Bowman R, Naguib A, Cooke J, Kuhnle GG, Burns PA, Luben R, Lentjes M, Khaw KT, Ball RY, Ibrahim AE, Arends MJ.

J Pathol. 2012 Nov;228(3):405-15. doi: 10.1002/path.4085. Epub 2012 Sep 28.

PMID:
22864938
30.

Dietary intakes and food sources of phytoestrogens in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24-hour dietary recall cohort.

Zamora-Ros R, Knaze V, Luján-Barroso L, Kuhnle GG, Mulligan AA, Touillaud M, Slimani N, Romieu I, Powell N, Tumino R, Peeters PH, de Magistris MS, Ricceri F, Sonestedt E, Drake I, Hjartåker A, Skie G, Mouw T, Wark PA, Romaguera D, Bueno-de-Mesquita HB, Ros M, Molina E, Sieri S, Quirós JR, Huerta JM, Tjønneland A, Halkjær J, Masala G, Teucher B, Kaas R, Travis RC, Dilis V, Benetou V, Trichopoulou A, Amiano P, Ardanaz E, Boeing H, Förster J, Clavel-Chapelon F, Fagherazzi G, Perquier F, Johansson G, Johansson I, Cassidy A, Overvad K, González CA.

Eur J Clin Nutr. 2012 Aug;66(8):932-41. doi: 10.1038/ejcn.2012.36. Epub 2012 Apr 18.

PMID:
22510793
31.

Carbon and nitrogen isotopic ratios of urine and faeces as novel nutritional biomarkers of meat and fish intake.

Kuhnle GG, Joosen AM, Kneale CJ, O'Connell TC.

Eur J Nutr. 2013 Feb;52(1):389-95. doi: 10.1007/s00394-012-0328-2. Epub 2012 Mar 10.

32.

Nutritional biomarkers for objective dietary assessment.

Kuhnle GG.

J Sci Food Agric. 2012 Apr;92(6):1145-9. doi: 10.1002/jsfa.5631. Epub 2012 Feb 20.

PMID:
22351524
33.

Estimated intake of dietary phyto-oestrogens in Australian women and evaluation of correlates of phyto-oestrogen intake.

Lahmann PH, Hughes MC, Ibiebele TI, Mulligan AA, Kuhnle GG, Webb PM.

J Nutr Sci. 2012 Sep 5;1:e11. doi: 10.1017/jns.2012.11. eCollection 2012.

34.

Red meat intake-induced increases in fecal water genotoxicity correlate with pro-carcinogenic gene expression changes in the human colon.

Hebels DG, Sveje KM, de Kok MC, van Herwijnen MH, Kuhnle GG, Engels LG, Vleugels-Simon CB, Mares WG, Pierik M, Masclee AA, Kleinjans JC, de Kok TM.

Food Chem Toxicol. 2012 Feb;50(2):95-103. doi: 10.1016/j.fct.2011.10.038. Epub 2011 Oct 14.

PMID:
22019696
35.

Association between dietary phyto-oestrogens and bone density in men and postmenopausal women.

Kuhnle GG, Ward HA, Vogiatzoglou A, Luben RN, Mulligan A, Wareham NJ, Forouhi NG, Khaw KT.

Br J Nutr. 2011 Oct;106(7):1063-9. doi: 10.1017/S0007114511001309. Epub 2011 May 17.

PMID:
21736835
36.

N-nitroso compound exposure-associated transcriptomic profiles are indicative of an increased risk for colorectal cancer.

Hebels DG, Sveje KM, de Kok MC, van Herwijnen MH, Kuhnle GG, Engels LG, Vleugels-Simon CB, Mares WG, Pierik M, Masclee AA, Kleinjans JC, de Kok TM.

Cancer Lett. 2011 Oct 1;309(1):1-10. doi: 10.1016/j.canlet.2011.05.007. Epub 2011 Jun 12.

37.

Phytoestrogen consumption and association with breast, prostate and colorectal cancer in EPIC Norfolk.

Ward HA, Kuhnle GG.

Arch Biochem Biophys. 2010 Sep 1;501(1):170-5. doi: 10.1016/j.abb.2010.05.018. Epub 2010 Jun 1. Review. Erratum in: Arch Biochem Biophys. 2014 Nov 15;562:123.

PMID:
20494649
38.

Effect of dietary meat and fish on endogenous nitrosation, inflammation and genotoxicity of faecal water.

Joosen AM, Lecommandeur E, Kuhnle GG, Aspinall SM, Kap L, Rodwell SA.

Mutagenesis. 2010 May;25(3):243-7. doi: 10.1093/mutage/gep070. Epub 2010 Jan 27.

PMID:
20106932
39.

Breast, colorectal, and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition-Norfolk in relation to phytoestrogen intake derived from an improved database.

Ward HA, Kuhnle GG, Mulligan AA, Lentjes MA, Luben RN, Khaw KT.

Am J Clin Nutr. 2010 Feb;91(2):440-8. doi: 10.3945/ajcn.2009.28282. Epub 2009 Dec 9.

PMID:
20007303
40.

Effect of processed and red meat on endogenous nitrosation and DNA damage.

Joosen AM, Kuhnle GG, Aspinall SM, Barrow TM, Lecommandeur E, Azqueta A, Collins AR, Bingham SA.

Carcinogenesis. 2009 Aug;30(8):1402-7. doi: 10.1093/carcin/bgp130. Epub 2009 Jun 4.

41.

Phytoestrogen content of cereals and cereal-based foods consumed in the UK.

Kuhnle GG, Dell'aquila C, Aspinall SM, Runswick SA, Mulligan AA, Bingham SA.

Nutr Cancer. 2009;61(3):302-9. doi: 10.1080/01635580802567141.

PMID:
19373603
42.

Phytoestrogen content of foods of animal origin: dairy products, eggs, meat, fish, and seafood.

Kuhnle GG, Dell'Aquila C, Aspinall SM, Runswick SA, Mulligan AA, Bingham SA.

J Agric Food Chem. 2008 Nov 12;56(21):10099-104. doi: 10.1021/jf801344x. Epub 2008 Oct 16.

PMID:
18922017
43.

Lack of prospective associations between plasma and urinary phytoestrogens and risk of prostate or colorectal cancer in the European Prospective into Cancer-Norfolk study.

Ward H, Chapelais G, Kuhnle GG, Luben R, Khaw KT, Bingham S.

Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2891-4. doi: 10.1158/1055-9965.EPI-08-0335.

44.

Urinary sucrose and fructose as biomarkers of sugar consumption: comparison of normal weight and obese volunteers.

Joosen AM, Kuhnle GG, Runswick SA, Bingham SA.

Int J Obes (Lond). 2008 Nov;32(11):1736-40. doi: 10.1038/ijo.2008.145. Epub 2008 Aug 26.

PMID:
18725895
45.

Phytoestrogen content of beverages, nuts, seeds, and oils.

Kuhnle GG, Dell'Aquila C, Aspinall SM, Runswick SA, Mulligan AA, Bingham SA.

J Agric Food Chem. 2008 Aug 27;56(16):7311-5. doi: 10.1021/jf801534g. Epub 2008 Aug 1.

PMID:
18671400
46.

Breast cancer risk in relation to urinary and serum biomarkers of phytoestrogen exposure in the European Prospective into Cancer-Norfolk cohort study.

Ward H, Chapelais G, Kuhnle GG, Luben R, Khaw KT, Bingham S; European Prospective into Cancer-Norfolk cohort.

Breast Cancer Res. 2008;10(2):R32. doi: 10.1186/bcr1995. Epub 2008 Apr 17.

47.

Detection and quantification of sucrose as dietary biomarker using gas chromatography and liquid chromatography with mass spectrometry.

Kuhnle GG, Joosen AM, Wood TR, Runswick SA, Griffin JL, Bingham SA.

Rapid Commun Mass Spectrom. 2008;22(3):279-82. doi: 10.1002/rcm.3355.

PMID:
18181249
48.

Flavanol monomer-induced changes to the human faecal microflora.

Tzounis X, Vulevic J, Kuhnle GG, George T, Leonczak J, Gibson GR, Kwik-Uribe C, Spencer JP.

Br J Nutr. 2008 Apr;99(4):782-92. Epub 2007 Nov 1.

PMID:
17977475
49.

Extraction and quantification of phytoestrogens in foods using automated solid-phase extraction and LC/MS/MS.

Kuhnle GG, Dell'aquila C, Low YL, Kussmaul M, Bingham SA.

Anal Chem. 2007 Dec 1;79(23):9234-9. Epub 2007 Nov 2.

PMID:
17975893
50.

Dietary meat, endogenous nitrosation and colorectal cancer.

Kuhnle GG, Bingham SA.

Biochem Soc Trans. 2007 Nov;35(Pt 5):1355-7. Review.

PMID:
17956350

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