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Items: 32


Therapeutic targeting of Notch signaling and immune checkpoint blockade in a spontaneous, genetically heterogeneous mouse model of T-cell acute lymphoblastic leukemia.

Gao J, Van Meter M, Hernandez Lopez S, Chen G, Huang Y, Ren S, Zhao Q, Rojas J, Gurer C, Thurston G, Kuhnert F.

Dis Model Mech. 2019 Sep 16;12(9). pii: dmm040931. doi: 10.1242/dmm.040931.


The Photorespiratory BOU Gene Mutation Alters Sulfur Assimilation and Its Crosstalk With Carbon and Nitrogen Metabolism in Arabidopsis thaliana.

Samuilov S, Brilhaus D, Rademacher N, Flachbart S, Arab L, Alfarraj S, Kuhnert F, Kopriva S, Weber APM, Mettler-Altmann T, Rennenberg H.

Front Plant Sci. 2018 Nov 27;9:1709. doi: 10.3389/fpls.2018.01709. eCollection 2018.


In Vitro Analysis of Metabolite Transport Proteins.

Roell MS, Kuhnert F, Zamani-Nour S, Weber APM.

Methods Mol Biol. 2017;1653:83-96. doi: 10.1007/978-1-4939-7225-8_6.


Gpr124 is essential for blood-brain barrier integrity in central nervous system disease.

Chang J, Mancuso MR, Maier C, Liang X, Yuki K, Yang L, Kwong JW, Wang J, Rao V, Vallon M, Kosinski C, Zhang JJ, Mah AT, Xu L, Li L, Gholamin S, Reyes TF, Li R, Kuhnert F, Han X, Yuan J, Chiou SH, Brettman AD, Daly L, Corney DC, Cheshier SH, Shortliffe LD, Wu X, Snyder M, Chan P, Giffard RG, Chang HY, Andreasson K, Kuo CJ.

Nat Med. 2017 Apr;23(4):450-460. doi: 10.1038/nm.4309. Epub 2017 Mar 13.


Phosphorylation of GENOMES UNCOUPLED 4 Alters Stimulation of Mg Chelatase Activity in Angiosperms.

Richter AS, Hochheuser C, Fufezan C, Heinze L, Kuhnert F, Grimm B.

Plant Physiol. 2016 Nov;172(3):1578-1595. Epub 2016 Sep 29.


Dll4 Blockade in Stromal Cells Mediates Antitumor Effects in Preclinical Models of Ovarian Cancer.

Kuhnert F, Chen G, Coetzee S, Thambi N, Hickey C, Shan J, Kovalenko P, Noguera-Troise I, Smith E, Fairhurst J, Andreev J, Kirshner JR, Papadopoulos N, Thurston G.

Cancer Res. 2015 Oct 1;75(19):4086-96. doi: 10.1158/0008-5472.CAN-14-3773. Epub 2015 Sep 16.


Dll4 blockade potentiates the anti-tumor effects of VEGF inhibition in renal cell carcinoma patient-derived xenografts.

Miles KM, Seshadri M, Ciamporcero E, Adelaiye R, Gillard B, Sotomayor P, Attwood K, Shen L, Conroy D, Kuhnert F, Lalani AS, Thurston G, Pili R.

PLoS One. 2014 Nov 13;9(11):e112371. doi: 10.1371/journal.pone.0112371. eCollection 2014.


Phosphorylation of transitory starch by α-glucan, water dikinase during starch turnover affects the surface properties and morphology of starch granules.

Mahlow S, Hejazi M, Kuhnert F, Garz A, Brust H, Baumann O, Fettke J.

New Phytol. 2014 Jul;203(2):495-507. doi: 10.1111/nph.12801. Epub 2014 Apr 3.


G Protein-Coupled Receptor 124 (GPR124) Gene Polymorphisms and Risk of Brain Arteriovenous Malformation.

Weinsheimer S, Brettman AD, Pawlikowska L, Wu DC, Mancuso MR, Kuhnert F, Lawton MT, Sidney S, Zaroff JG, McCulloch CE, Young WL, Kuo C, Kim H.

Transl Stroke Res. 2012 Dec;3(4):418-27. doi: 10.1007/s12975-012-0202-9. Epub 2012 Aug 14.


Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling.

Shkreli M, Sarin KY, Pech MF, Papeta N, Chang W, Brockman SA, Cheung P, Lee E, Kuhnert F, Olson JL, Kuo CJ, Gharavi AG, D'Agati VD, Artandi SE.

Nat Med. 2011 Dec 4;18(1):111-9. doi: 10.1038/nm.2550.


Dll4-Notch signaling as a therapeutic target in tumor angiogenesis.

Kuhnert F, Kirshner JR, Thurston G.

Vasc Cell. 2011 Sep 18;3(1):20. doi: 10.1186/2045-824X-3-20.


Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis.

Lin SL, Chang FC, Schrimpf C, Chen YT, Wu CF, Wu VC, Chiang WC, Kuhnert F, Kuo CJ, Chen YM, Wu KD, Tsai TJ, Duffield JS.

Am J Pathol. 2011 Feb;178(2):911-23. doi: 10.1016/j.ajpath.2010.10.012.


Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124.

Kuhnert F, Mancuso MR, Shamloo A, Wang HT, Choksi V, Florek M, Su H, Fruttiger M, Young WL, Heilshorn SC, Kuo CJ.

Science. 2010 Nov 12;330(6006):985-9. doi: 10.1126/science.1196554.


VEGF signaling has distinct spatiotemporal roles during heart valve development.

Stankunas K, Ma GK, Kuhnert FJ, Kuo CJ, Chang CP.

Dev Biol. 2010 Nov 15;347(2):325-36. doi: 10.1016/j.ydbio.2010.08.030. Epub 2010 Sep 15.


miR-17-92 angiogenesis micromanagement.

Kuhnert F, Kuo CJ.

Blood. 2010 Jun 10;115(23):4631-3. doi: 10.1182/blood-2010-03-276428. No abstract available.


Targeted Vezf1-null mutation impairs vascular structure formation during embryonic stem cell differentiation.

Zou Z, Ocaya PA, Sun H, Kuhnert F, Stuhlmann H.

Arterioscler Thromb Vasc Biol. 2010 Jul;30(7):1378-88. doi: 10.1161/ATVBAHA.109.200428. Epub 2010 Apr 29.


Angiopoietin/Tie2 signaling transforms capillaries into venules primed for leukocyte trafficking in airway inflammation.

Fuxe J, Lashnits E, O'Brien S, Baluk P, Tabruyn SP, Kuhnert F, Kuo C, Thurston G, McDonald DM.

Am J Pathol. 2010 Apr;176(4):2009-18. doi: 10.2353/ajpath.2010.090976. Epub 2010 Feb 4.


Cellular source and amount of vascular endothelial growth factor and platelet-derived growth factor in tumors determine response to angiogenesis inhibitors.

Sennino B, Kuhnert F, Tabruyn SP, Mancuso MR, Hu-Lowe DD, Kuo CJ, McDonald DM.

Cancer Res. 2009 May 15;69(10):4527-36. doi: 10.1158/0008-5472.CAN-08-3779. Epub 2009 Apr 28.


Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis.

Daneman R, Agalliu D, Zhou L, Kuhnert F, Kuo CJ, Barres BA.

Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):641-6. doi: 10.1073/pnas.0805165106. Epub 2009 Jan 7. Erratum in: Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6422.


Developmental angiogenesis of the central nervous system.

Mancuso MR, Kuhnert F, Kuo CJ.

Lymphat Res Biol. 2008;6(3-4):173-80. doi: 10.1089/lrb.2008.1014. Review.


Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126.

Kuhnert F, Mancuso MR, Hampton J, Stankunas K, Asano T, Chen CZ, Kuo CJ.

Development. 2008 Dec;135(24):3989-93. doi: 10.1242/dev.029736. Epub 2008 Nov 5.


Soluble receptor-mediated selective inhibition of VEGFR and PDGFRbeta signaling during physiologic and tumor angiogenesis.

Kuhnert F, Tam BY, Sennino B, Gray JT, Yuan J, Jocson A, Nayak NR, Mulligan RC, McDonald DM, Kuo CJ.

Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10185-90. doi: 10.1073/pnas.0803194105. Epub 2008 Jul 16.


Recombinant adenovirus as a methodology for exploration of physiologic functions of growth factor pathways.

Wei K, Kuhnert F, Kuo CJ.

J Mol Med (Berl). 2008 Feb;86(2):161-9. Epub 2007 Sep 22. Review.


Dosage-dependent requirement for mouse Vezf1 in vascular system development.

Kuhnert F, Campagnolo L, Xiong JW, Lemons D, Fitch MJ, Zou Z, Kiosses WB, Gardner H, Stuhlmann H.

Dev Biol. 2005 Jul 1;283(1):140-56.


Identifying early vascular genes through gene trapping in mouse embryonic stem cells.

Kuhnert F, Stuhlmann H.

Curr Top Dev Biol. 2004;62:261-81. Review. No abstract available.


Egfl7, a novel epidermal growth factor-domain gene expressed in endothelial cells.

Fitch MJ, Campagnolo L, Kuhnert F, Stuhlmann H.

Dev Dyn. 2004 Jun;230(2):316-24.


Wnts as essential growth factors for the adult small intestine and colon.

Hoffman J, Kuhnert F, Davis CR, Kuo CJ.

Cell Cycle. 2004 May;3(5):554-7. Epub 2004 May 15.


Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1.

Kuhnert F, Davis CR, Wang HT, Chu P, Lee M, Yuan J, Nusse R, Kuo CJ.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):266-71. Epub 2003 Dec 26.


[Partly automated in vitro feeding of adult Amblyomma hebraeum]

Kuhnert F, Issmer AE, Grunewald J.

ALTEX. 1998;15(2):67-72.


Use of developmental marker genes to define temporal and spatial patterns of differentiation during embryoid body formation.

Leahy A, Xiong JW, Kuhnert F, Stuhlmann H.

J Exp Zool. 1999 Jun 15;284(1):67-81.


The life-cycle of the bont tick Amblyomma hebraeum in vitro.

Kuhnert F, Diehl PA, Guerin PM.

Int J Parasitol. 1995 Aug;25(8):887-96.


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