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Items: 14


Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway.

Kashyap MK, Kumar D, Jones H, Amaya-Chanaga CI, Choi MY, Melo-Cardenas J, Ale-Ali A, Kuhne MR, Sabbatini P, Cohen LJ, Shelat SG, Rassenti LZ, Kipps TJ, Cardarelli PM, Castro JE.

Oncotarget. 2016 Jan 19;7(3):2809-22. doi: 10.18632/oncotarget.6465.


BMS-936564/MDX-1338: a fully human anti-CXCR4 antibody induces apoptosis in vitro and shows antitumor activity in vivo in hematologic malignancies.

Kuhne MR, Mulvey T, Belanger B, Chen S, Pan C, Chong C, Cao F, Niekro W, Kempe T, Henning KA, Cohen LJ, Korman AJ, Cardarelli PM.

Clin Cancer Res. 2013 Jan 15;19(2):357-66. doi: 10.1158/1078-0432.CCR-12-2333. Epub 2012 Dec 4.


A nonfucosylated human antibody to CD19 with potent B-cell depletive activity for therapy of B-cell malignancies.

Cardarelli PM, Rao-Naik C, Chen S, Huang H, Pham A, Moldovan-Loomis MC, Pan C, Preston B, Passmore D, Liu J, Kuhne MR, Witte A, Blanset D, King DJ.

Cancer Immunol Immunother. 2010 Feb;59(2):257-65. doi: 10.1007/s00262-009-0746-z.


In vitro and in vivo characterization of MDX-1401 for therapy of malignant lymphoma.

Cardarelli PM, Moldovan-Loomis MC, Preston B, Black A, Passmore D, Chen TH, Chen S, Liu J, Kuhne MR, Srinivasan M, Assad A, Witte A, Graziano RF, King DJ.

Clin Cancer Res. 2009 May 15;15(10):3376-83. doi: 10.1158/1078-0432.CCR-08-3222. Epub 2009 Apr 28.


Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell.

Yablonski D, Kuhne MR, Kadlecek T, Weiss A.

Science. 1998 Jul 17;281(5375):413-6.


Assembly and regulation of the CD40 receptor complex in human B cells.

Kuhné MR, Robbins M, Hambor JE, Mackey MF, Kosaka Y, Nishimura T, Gigley JP, Noelle RJ, Calderhead DM.

J Exp Med. 1997 Jul 21;186(2):337-42.


Evidence against dephosphorylation of insulin-elicited phosphotyrosine proteins in vivo by the phosphatase PTP2C.

Kuhné MR, Zhao Z, Lienhard GE.

Biochem Biophys Res Commun. 1995 Jun 6;211(1):190-7.


Dephosphorylation of insulin receptor substrate 1 by the tyrosine phosphatase PTP2C.

Kuhné MR, Zhao Z, Rowles J, Lavan BE, Shen SH, Fischer EH, Lienhard GE.

J Biol Chem. 1994 Jun 3;269(22):15833-7.


Insulin and IGF-I signaling through the insulin receptor substrate 1.

Keller SR, Lamphere L, Lavan BE, Kuhné MR, Lienhard GE.

Mol Reprod Dev. 1993 Aug;35(4):346-51; discussion 351-2. Review.


Novel regulation of an MHC class I gene response to interferon-gamma.

Schwarz DA, Buhlmann JE, Kuhne MR, Lam TM, White HD, Green WR.

Cell Immunol. 1993 Aug;150(1):90-100.


The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp.

Kuhné MR, Pawson T, Lienhard GE, Feng GS.

J Biol Chem. 1993 Jun 5;268(16):11479-81.


The association of insulin-elicited phosphotyrosine proteins with src homology 2 domains.

Lavan BE, Kuhné MR, Garner CW, Anderson D, Reedijk M, Pawson T, Lienhard GE.

J Biol Chem. 1992 Jun 5;267(16):11631-6.

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