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Items: 1 to 50 of 461

1.

CART Peptide Regulates Psychostimulant-Induced Activity and Exhibits a Rate Dependency.

Kuhar MJ, Job MO.

J Drug Alcohol Res. 2017;6. pii: 236032. doi: 10.4303/jdar/236032. Epub 2017 May 26. No abstract available.

2.

CART peptide in the nucleus accumbens regulates psychostimulants: Correlations between psychostimulant and CART peptide effects.

Job MO, Kuhar MJ.

Neuroscience. 2017 Apr 21;348:135-142. doi: 10.1016/j.neuroscience.2017.02.012. Epub 2017 Feb 16.

3.

CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.

Abels M, Riva M, Bennet H, Ahlqvist E, Dyachok O, Nagaraj V, Shcherbina L, Fred RG, Poon W, Sörhede-Winzell M, Fadista J, Lindqvist A, Kask L, Sathanoori R, Dekker-Nitert M, Kuhar MJ, Ahrén B, Wollheim CB, Hansson O, Tengholm A, Fex M, Renström E, Groop L, Lyssenko V, Wierup N.

Diabetologia. 2016 Sep;59(9):1928-37. doi: 10.1007/s00125-016-4020-6. Epub 2016 Jun 23.

PMID:
27338624
4.

CART Peptides and Drugs of Abuse: A Review of Recent Progress.

Kuhar MJ.

J Drug Alcohol Res. 2016;5. pii: 235984. doi: 10.4303/jdar/235984. Epub 2016 Jun 28.

5.

Cocaine-and-Amphetamine Regulated Transcript (CART) peptide attenuates dopamine- and cocaine-mediated locomotor activity in both male and female rats: lack of sex differences.

Job MO, Perry J, Shen LL, Kuhar MJ.

Neuropeptides. 2014 Apr;48(2):75-81. doi: 10.1016/j.npep.2014.01.002. Epub 2014 Jan 10.

6.

Letter from the Editor-in-Chief: Irreproducible Results.

Kuhar MJ.

J Drug Alcohol Res. 2014;3. pii: 235879. No abstract available.

7.

Affinity labeling of membrane receptors using tissue-penetrating radiations.

Wong FC, Boja J, Ho B, Kuhar MJ, Wong DF.

Biomed Res Int. 2013;2013:503095. doi: 10.1155/2013/503095. Epub 2013 Jun 27.

8.

The inhibition of cocaine-induced locomotor activity by CART 55-102 is lost after repeated cocaine administration.

Job MO, Shen LL, Kuhar MJ.

Neurosci Lett. 2013 Aug 29;550:179-83. doi: 10.1016/j.neulet.2013.06.039. Epub 2013 Jun 29.

9.

Intra-accumbal administration of shRNAs against CART peptides cause increases in body weight and cocaine-induced locomotor activity in rats.

Job MO, Licata J, Hubert GW, Kuhar MJ.

Brain Res. 2012 Oct 30;1482:47-54. doi: 10.1016/j.brainres.2012.09.005. Epub 2012 Sep 11.

10.

Region- and sex-specific changes in CART mRNA in rat hypothalamic nuclei induced by forced swim stress.

Balkan B, Gozen O, Koylu EO, Keser A, Kuhar MJ, Pogun S.

Brain Res. 2012 Oct 15;1479:62-71. doi: 10.1016/j.brainres.2012.08.043. Epub 2012 Aug 31.

11.

Collegial ethics: supporting our colleagues.

Kuhar MJ, Cross D.

Sci Eng Ethics. 2013 Sep;19(3):677-84. doi: 10.1007/s11948-012-9364-9.

12.

Collegial ethics: what, why and how.

Kuhar MJ.

Drug Alcohol Depend. 2011 Dec 15;119(3):235-8.

13.
14.

The cocaine- and amphetamine-regulated transcript mediates ligand-independent activation of ERα, and is an independent prognostic factor in node-negative breast cancer.

Brennan DJ, O'Connor DP, Laursen H, McGee SF, McCarthy S, Zagozdzon R, Rexhepaj E, Culhane AC, Martin FM, Duffy MJ, Landberg G, Ryden L, Hewitt SM, Kuhar MJ, Bernards R, Millikan RC, Crown JP, Jirström K, Gallagher WM.

Oncogene. 2012 Jul 26;31(30):3483-94. doi: 10.1038/onc.2011.519. Epub 2011 Dec 5.

15.

Forced swim stress elicits region-specific changes in CART expression in the stress axis and stress regulatory brain areas.

Balkan B, Keser A, Gozen O, Koylu EO, Dagci T, Kuhar MJ, Pogun S.

Brain Res. 2012 Jan 13;1432:56-65. doi: 10.1016/j.brainres.2011.11.006. Epub 2011 Nov 9.

PMID:
22137563
16.

CART Peptides Regulate Psychostimulants and May be Endogenous Antidepressants.

Job MO, McNamara IM, Kuhar MJ.

Curr Neuropharmacol. 2011 Mar;9(1):12-6. doi: 10.2174/157015911795017074.

17.

Understanding the Global Problem of Drug Addiction is a Challenge for IDARS Scientists.

Ali SF, Onaivi ES, Dodd PR, Cadet JL, Schenk S, Kuhar MJ, Koob GF.

Curr Neuropharmacol. 2011 Mar;9(1):2-7. doi: 10.2174/157015911795017245.

18.

CART peptide stimulation of G protein-mediated signaling in differentiated PC12 cells: identification of PACAP 6-38 as a CART receptor antagonist.

Lin Y, Hall RA, Kuhar MJ.

Neuropeptides. 2011 Oct;45(5):351-8. doi: 10.1016/j.npep.2011.07.006. Epub 2011 Aug 19.

20.

Chromatin immunoprecipitation assays revealed CREB and serine 133 phospho-CREB binding to the CART gene proximal promoter.

Rogge GA, Shen LL, Kuhar MJ.

Brain Res. 2010 Jul 16;1344:1-12. doi: 10.1016/j.brainres.2010.04.069. Epub 2010 May 6.

21.

Wake promoting effects of cocaine and amphetamine-regulated transcript (CART).

Keating GL, Kuhar MJ, Bliwise DL, Rye DB.

Neuropeptides. 2010 Jun;44(3):241-6. doi: 10.1016/j.npep.2009.12.013. Epub 2010 Feb 8.

22.

Cocaine and amphetamine-regulated transcript-containing neurons in the nucleus accumbens project to the ventral pallidum in the rat and may inhibit cocaine-induced locomotion.

Hubert GW, Manvich DF, Kuhar MJ.

Neuroscience. 2010 Jan 13;165(1):179-87. doi: 10.1016/j.neuroscience.2009.10.013. Epub 2009 Oct 12.

23.

Measuring levels of proteins by various technologies: can we learn more by measuring turnover?

Kuhar MJ.

Biochem Pharmacol. 2010 Mar 1;79(5):665-8. doi: 10.1016/j.bcp.2009.09.029. Epub 2009 Oct 6.

24.

Regulation of cocaine- and amphetamine-regulated transcript mRNA expression by calcium-mediated signaling in GH3 cells.

Jones DC, Lakatos A, Rogge GA, Kuhar MJ.

Neuroscience. 2009 May 5;160(2):339-47. doi: 10.1016/j.neuroscience.2009.02.051. Epub 2009 Mar 1.

PMID:
19258027
25.

Blacklisting among scientists.

Kuhar MJ.

Synapse. 2009 Jul;63(7):539-40. doi: 10.1002/syn.20638. No abstract available.

26.

Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo.

Rogge GA, Jones DC, Green T, Nestler E, Kuhar MJ.

Brain Res. 2009 Jan 28;1251:42-52. doi: 10.1016/j.brainres.2008.11.011. Epub 2008 Nov 14.

27.

On the use of protein turnover and half-lives.

Kuhar MJ.

Neuropsychopharmacology. 2009 Apr;34(5):1172-3. doi: 10.1038/npp.2008.190. Epub 2008 Oct 15. No abstract available.

28.

CART peptides: regulators of body weight, reward and other functions.

Rogge G, Jones D, Hubert GW, Lin Y, Kuhar MJ.

Nat Rev Neurosci. 2008 Oct;9(10):747-58. doi: 10.1038/nrn2493. Review. Erratum in: Nat Rev Neurosci. 2010 Mar;11(3):218. Dosage error in article text.

29.

On blacklisting in science.

Kuhar MJ.

Sci Eng Ethics. 2008 Sep;14(3):301-3. doi: 10.1007/s11948-008-9082-5. Epub 2008 Jul 31. No abstract available.

PMID:
18668347
30.

CART deficiency increases body weight but does not alter bone strength.

Bartell SM, Isales CM, Baile CA, Kuhar MJ, Hamrick MW.

J Musculoskelet Neuronal Interact. 2008 Apr-Jun;8(2):146-53.

31.

Unique responses of midbrain CART neurons in macaques to ovarian steroids.

Lima FB, Henderson JA, Reddy AP, Tokuyama Y, Hubert GW, Kuhar MJ, Bethea CL.

Brain Res. 2008 Aug 28;1227:76-88. doi: 10.1016/j.brainres.2008.05.078. Epub 2008 Jun 10.

32.

Frequency of maternal licking and grooming correlates negatively with vulnerability to cocaine and alcohol use in rats.

Francis DD, Kuhar MJ.

Pharmacol Biochem Behav. 2008 Sep;90(3):497-500. doi: 10.1016/j.pbb.2008.04.012. Epub 2008 Apr 26.

33.

Injection of CART (cocaine- and amphetamine-regulated transcript) peptide into the nucleus accumbens reduces cocaine self-administration in rats.

Jaworski JN, Hansen ST, Kuhar MJ, Mark GP.

Behav Brain Res. 2008 Aug 22;191(2):266-71. doi: 10.1016/j.bbr.2008.03.039. Epub 2008 Apr 7.

34.

Cocaine administration increases the fraction of CART cells in the rat nucleus accumbens that co-immunostain for c-Fos.

Hubert GW, Kuhar MJ.

Neuropeptides. 2008 Jun;42(3):339-43. doi: 10.1016/j.npep.2008.01.001. Epub 2008 Mar 7.

35.

High dose CART peptide induces abnormal EEG activity and behavioral seizures.

Keating GL, Kuhar MJ, Rye DB.

Neuropeptides. 2008 Apr;42(2):199-204. doi: 10.1016/j.npep.2007.11.005. Epub 2008 Feb 21.

PMID:
18178249
36.

CART receptor binding in primary cell cultures of the rat nucleus accumbens.

Jones DC, Kuhar MJ.

Synapse. 2008 Feb;62(2):122-7.

PMID:
18000808
37.

Increased metabolism in the R6/2 mouse model of Huntington's disease.

van der Burg JM, Bacos K, Wood NI, Lindqvist A, Wierup N, Woodman B, Wamsteeker JI, Smith R, Deierborg T, Kuhar MJ, Bates GP, Mulder H, Erlanson-Albertsson C, Morton AJ, Brundin P, Petersén A, Björkqvist M.

Neurobiol Dis. 2008 Jan;29(1):41-51. Epub 2007 Aug 24.

PMID:
17920283
38.

CART peptides as modulators of dopamine and psychostimulants and interactions with the mesolimbic dopaminergic system.

Hubert GW, Jones DC, Moffett MC, Rogge G, Kuhar MJ.

Biochem Pharmacol. 2008 Jan 1;75(1):57-62. Epub 2007 Jul 26. Review.

39.

CART-peptide immunoreactivity in enteric nerves in patients with Hirschsprung's disease.

Gunnarsdóttir A, Wierup N, Larsson LT, Kuhar MJ, Ekblad E.

Eur J Pediatr Surg. 2007 Jun;17(3):184-9.

PMID:
17638157
40.

Synthesis, monoamine transporter binding, properties, and functional monoamine uptake activity of 3beta-[4-methylphenyl and 4-chlorophenyl]-2 beta-[5-(substituted phenyl)thiazol-2-yl]tropanes.

Gong PK, Blough BE, Brieaddy LE, Huang X, Kuhar MJ, Navarro HA, Carroll FI.

J Med Chem. 2007 Jul 26;50(15):3686-95. Epub 2007 Jun 30.

PMID:
17602602
41.
42.

Intra-VTA CART 55-102 reduces the locomotor effect of systemic cocaine in rats: an isobolographic analysis.

Jaworski JN, Kimmel HL, Mitrano DA, Tallarida RJ, Kuhar MJ.

Neuropeptides. 2007 Apr;41(2):65-72. Epub 2007 Feb 7.

43.

Effects of dopamine transporter selective 3-phenyltropane analogs on locomotor activity, drug discrimination, and cocaine self-administration after oral administration.

Carroll FI, Fox BS, Kuhar MJ, Howard JL, Pollard GT, Schenk S.

Eur J Pharmacol. 2006 Dec 28;553(1-3):149-56. Epub 2006 Sep 23.

PMID:
17067572
44.

Colocalization of CART peptide with prodynorphin and dopamine D1 receptors in the rat nucleus accumbens.

Hubert GW, Kuhar MJ.

Neuropeptides. 2006 Dec;40(6):409-15. Epub 2006 Oct 24.

PMID:
17064765
45.

Maternal separation alters drug intake patterns in adulthood in rats.

Moffett MC, Vicentic A, Kozel M, Plotsky P, Francis DD, Kuhar MJ.

Biochem Pharmacol. 2007 Feb 1;73(3):321-30. Epub 2006 Sep 8. Review.

46.

Should Codes of Ethics include expectations of others?

Kuhar MJ.

Sci Eng Ethics. 2006 Jul;12(3):413-4. No abstract available.

PMID:
16909145
47.

Cocaine and amphetamine regulated transcript (CART) and the stress response.

Koylu EO, Balkan B, Kuhar MJ, Pogun S.

Peptides. 2006 Aug;27(8):1956-69. Epub 2006 Jul 5. Review.

PMID:
16822586
48.

Intrathecal CART (55-102) attenuates hyperlagesia and allodynia in a mouse model of neuropathic but not inflammatory pain.

Damaj MI, Zheng J, Martin BR, Kuhar MJ.

Peptides. 2006 Aug;27(8):2019-23. Epub 2006 Jul 11.

PMID:
16814901
49.

CART expression in limbic regions of rat brain following forced swim stress: sex differences.

Balkan B, Gozen O, Yararbas G, Koylu EO, Akinturk S, Kuhar MJ, Pogun S.

Neuropeptides. 2006 Jun;40(3):185-93. Epub 2006 Apr 27.

PMID:
16644010
50.

Development of the dopamine transporter selective RTI-336 as a pharmacotherapy for cocaine abuse.

Carroll FI, Howard JL, Howell LL, Fox BS, Kuhar MJ.

AAPS J. 2006 Mar 24;8(1):E196-203. Review.

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