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Items: 12

1.

Flagellin-mediated activation of IL-33-ST2 signaling by a pathobiont promotes intestinal fibrosis.

Imai J, Kitamoto S, Sugihara K, Nagao-Kitamoto H, Hayashi A, Morhardt TL, Kuffa P, Higgins PDR, Barnich N, Kamada N.

Mucosal Immunol. 2019 May;12(3):632-643. doi: 10.1038/s41385-019-0138-4. Epub 2019 Feb 11.

2.

IL-10 produced by macrophages regulates epithelial integrity in the small intestine.

Morhardt TL, Hayashi A, Ochi T, Quirós M, Kitamoto S, Nagao-Kitamoto H, Kuffa P, Atarashi K, Honda K, Kao JY, Nusrat A, Kamada N.

Sci Rep. 2019 Feb 4;9(1):1223. doi: 10.1038/s41598-018-38125-x.

3.

Functional Characterization of Inflammatory Bowel Disease-Associated Gut Dysbiosis in Gnotobiotic Mice.

Nagao-Kitamoto H, Shreiner AB, Gillilland MG 3rd, Kitamoto S, Ishii C, Hirayama A, Kuffa P, El-Zaatari M, Grasberger H, Seekatz AM, Higgins PD, Young VB, Fukuda S, Kao JY, Kamada N.

Cell Mol Gastroenterol Hepatol. 2016 Mar 3;2(4):468-481. eCollection 2016 Jul.

4.

Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.

Ochi T, Feng Y, Kitamoto S, Nagao-Kitamoto H, Kuffa P, Atarashi K, Honda K, Teitelbaum DH, Kamada N.

Sci Rep. 2016 Jun 15;6:27634. doi: 10.1038/srep27634.

5.

Pathogenic role of the gut microbiota in gastrointestinal diseases.

Nagao-Kitamoto H, Kitamoto S, Kuffa P, Kamada N.

Intest Res. 2016 Apr;14(2):127-38. doi: 10.5217/ir.2016.14.2.127. Epub 2016 Apr 27. Review.

6.

Regulation of virulence: the rise and fall of gastrointestinal pathogens.

Kitamoto S, Nagao-Kitamoto H, Kuffa P, Kamada N.

J Gastroenterol. 2016 Mar;51(3):195-205. doi: 10.1007/s00535-015-1141-5. Epub 2015 Nov 10. Review.

7.

Intestinal macrophages arising from CCR2(+) monocytes control pathogen infection by activating innate lymphoid cells.

Seo SU, Kuffa P, Kitamoto S, Nagao-Kitamoto H, Rousseau J, Kim YG, Núñez G, Kamada N.

Nat Commun. 2015 Aug 13;6:8010. doi: 10.1038/ncomms9010.

8.

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.

Muñoz-Planillo R, Kuffa P, Martínez-Colón G, Smith BL, Rajendiran TM, Núñez G.

Immunity. 2013 Jun 27;38(6):1142-53. doi: 10.1016/j.immuni.2013.05.016.

9.

NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense.

Franchi L, Kamada N, Nakamura Y, Burberry A, Kuffa P, Suzuki S, Shaw MH, Kim YG, Núñez G.

Nat Immunol. 2012 May;13(5):449-56. doi: 10.1038/ni.2263.

10.

A dual role for the API2 moiety in API2-MALT1-dependent NF-kappaB activation: heterotypic oligomerization and TRAF2 recruitment.

Lucas PC, Kuffa P, Gu S, Kohrt D, Kim DS, Siu K, Jin X, Swenson J, McAllister-Lucas LM.

Oncogene. 2007 Aug 16;26(38):5643-54. Epub 2007 Mar 5.

PMID:
17334391
11.

CARMA3/Bcl10/MALT1-dependent NF-kappaB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cells.

McAllister-Lucas LM, Ruland J, Siu K, Jin X, Gu S, Kim DS, Kuffa P, Kohrt D, Mak TW, Nuñez G, Lucas PC.

Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):139-44. Epub 2006 Nov 13.

12.

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.

Ohren JF, Chen H, Pavlovsky A, Whitehead C, Zhang E, Kuffa P, Yan C, McConnell P, Spessard C, Banotai C, Mueller WT, Delaney A, Omer C, Sebolt-Leopold J, Dudley DT, Leung IK, Flamme C, Warmus J, Kaufman M, Barrett S, Tecle H, Hasemann CA.

Nat Struct Mol Biol. 2004 Dec;11(12):1192-7. Epub 2004 Nov 14. Erratum in: Nat Struct Mol Biol. 2005 Mar;12(3):278.

PMID:
15543157

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