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Blast-Mediated Traumatic Brain Injury Exacerbates Retinal Damage and Amyloidosis in the APPswePSENd19e Mouse Model of Alzheimer's Disease.

Harper MM, Hedberg-Buenz A, Herlein J, Abrahamson EE, Anderson MG, Kuehn MH, Kardon RH, Poolman P, Ikonomovic MD.

Invest Ophthalmol Vis Sci. 2019 Jun 3;60(7):2716-2725. doi: 10.1167/iovs.18-26353.


Histochemical Analysis of Glaucoma Caused by a Myocilin Mutation in a Human Donor Eye.

van der Heide CJ, Alward WLM, Flamme-Wiese M, Riker M, Syed NA, Anderson MG, Carter K, Kuehn MH, Stone EM, Mullins RF, Fingert JH.

Ophthalmol Glaucoma. 2018 Sep-Oct;1(2):132-138. doi: 10.1016/j.ogla.2018.08.004. Epub 2018 Aug 17.


Primary closed angle glaucoma in the Basset Hound: Genetic investigations using genome-wide association and RNA sequencing strategies.

Oliver JAC, Ricketts SL, Kuehn MH, Mellersh CS.

Mol Vis. 2019 Feb 8;25:93-105. eCollection 2019.


Focusing on the future from afar: Self-distancing from future stressors facilitates adaptive coping.

White RE, Kuehn MM, Duckworth AL, Kross E, Ayduk Ö.

Emotion. 2019 Aug;19(5):903-916. doi: 10.1037/emo0000491. Epub 2018 Sep 17.


Optical coherence tomography and molecular analysis of sudden acquired retinal degeneration syndrome (SARDS) eyes suggests the immune-mediated nature of retinal damage.

Grozdanic SD, Lazic T, Kecova H, Mohan K, Kuehn MH.

Vet Ophthalmol. 2019 May;22(3):305-327. doi: 10.1111/vop.12597. Epub 2018 Aug 15.


Genetic Survey of Adult-Onset Idiopathic Intracranial Hypertension.

Kuehn MH, Mishra R, Deonovic BE, Miller KN, McCormack SE, Liu GT, Kupersmith MJ, Wall M; NORDIC IIHTT Study Group.

J Neuroophthalmol. 2019 Mar;39(1):50-55. doi: 10.1097/WNO.0000000000000648.


Integrating Spiritual Care During Interprofessional Simulation for Baccalaureate Nursing Students.

Huehn SL, Kuehn MB, Fick KE.

J Holist Nurs. 2019 Mar;37(1):94-99. doi: 10.1177/0898010118765203. Epub 2018 Mar 29.


Consensus recommendations for trabecular meshwork cell isolation, characterization and culture.

Keller KE, Bhattacharya SK, Borrás T, Brunner TM, Chansangpetch S, Clark AF, Dismuke WM, Du Y, Elliott MH, Ethier CR, Faralli JA, Freddo TF, Fuchshofer R, Giovingo M, Gong H, Gonzalez P, Huang A, Johnstone MA, Kaufman PL, Kelley MJ, Knepper PA, Kopczynski CC, Kuchtey JG, Kuchtey RW, Kuehn MH, Lieberman RL, Lin SC, Liton P, Liu Y, Lütjen-Drecoll E, Mao W, Masis-Solano M, McDonnell F, McDowell CM, Overby DR, Pattabiraman PP, Raghunathan VK, Rao PV, Rhee DJ, Chowdhury UR, Russell P, Samples JR, Schwartz D, Stubbs EB, Tamm ER, Tan JC, Toris CB, Torrejon KY, Vranka JA, Wirtz MK, Yorio T, Zhang J, Zode GS, Fautsch MP, Peters DM, Acott TS, Stamer WD.

Exp Eye Res. 2018 Jun;171:164-173. doi: 10.1016/j.exer.2018.03.001. Epub 2018 Mar 9. Review.


Value Frameworks in Oncology: Comparative Analysis and Implications to the Pharmaceutical Industry.

Slomiany M, Madhavan P, Kuehn M, Richardson S.

Am Health Drug Benefits. 2017 Jul;10(5):253-260. Review.


Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins.

Finethy R, Luoma S, Orench-Rivera N, Feeley EM, Haldar AK, Yamamoto M, Kanneganti TD, Kuehn MJ, Coers J.

MBio. 2017 Oct 3;8(5). pii: e01188-17. doi: 10.1128/mBio.01188-17.


The Ability of Nitric Oxide to Lower Intraocular Pressure Is Dependent on Guanylyl Cyclase.

Muenster S, Lieb WS, Fabry G, Allen KN, Kamat SS, Guy AH, Dordea AC, Teixeira L, Tainsh RE, Yu B, Zhu W, Ashpole NE, Malhotra R, Brouckaert P, Bloch DB, Scherrer-Crosbie M, Stamer WD, Kuehn MH, Pasquale LR, Buys ES.

Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4826-4835. doi: 10.1167/iovs.17-22168.


Improving Collaboration Among Social Work and Nursing Students Through Interprofessional Simulation.

Kuehn MB, Huehn S, Smalling S.

Creat Nurs. 2017 Aug 1;23(3):179-183. doi: 10.1891/1078-4535.23.3.179.


Restoration of Aqueous Humor Outflow Following Transplantation of iPSC-Derived Trabecular Meshwork Cells in a Transgenic Mouse Model of Glaucoma.

Zhu W, Jain A, Gramlich OW, Tucker BA, Sheffield VC, Kuehn MH.

Invest Ophthalmol Vis Sci. 2017 Apr 1;58(4):2054-2062. doi: 10.1167/iovs.16-20672.


Breaking the bilayer: OMV formation during environmental transitions.

Bonnington KE, Kuehn MJ.

Microb Cell. 2017 Feb 3;4(2):64-66. doi: 10.15698/mic2017.02.558.


MMP19 expression in the human optic nerve.

Chirco KR, Hazlewood RJ, Miller K, Workalemahu G, Jampol LM, Lesser GR, Mullins RF, Kuehn MH, Fingert JH.

Mol Vis. 2016 Dec 14;22:1429-1436. eCollection 2016.


Sustained Delivery of Timolol Maleate for Over 90 Days by Subconjunctival Injection.

Lavik E, Kuehn MH, Shoffstall AJ, Atkins K, Dumitrescu AV, Kwon YH.

J Ocul Pharmacol Ther. 2016 Dec;32(10):642-649. Epub 2016 Nov 11.


Environmentally controlled bacterial vesicle-mediated export.

Orench-Rivera N, Kuehn MJ.

Cell Microbiol. 2016 Nov;18(11):1525-1536. doi: 10.1111/cmi.12676. Review.


A standardized method to determine the concentration of extracellular vesicles using tunable resistive pulse sensing.

Vogel R, Coumans FA, Maltesen RG, Böing AN, Bonnington KE, Broekman ML, Broom MF, Buzás EI, Christiansen G, Hajji N, Kristensen SR, Kuehn MJ, Lund SM, Maas SL, Nieuwland R, Osteikoetxea X, Schnoor R, Scicluna BJ, Shambrook M, de Vrij J, Mann SI, Hill AF, Pedersen S.

J Extracell Vesicles. 2016 Sep 27;5:31242. doi: 10.3402/jev.v5.31242. eCollection 2016.


Correction: A Mutation in LTBP2 Causes Congenital Glaucoma in Domestic Cats (Felis catus).

Kuehn MH, Lipsett KA, Menotti-Raymond M, Whitmore SS, Scheetz TE, David VA, O'Brien SJ, Zhao Z, Jens JK, Snella EM, Ellinwood NM, McLellan GJ.

PLoS One. 2016 Aug 18;11(8):e0161517. doi: 10.1371/journal.pone.0161517. eCollection 2016.


Transplantation of iPSC-derived TM cells rescues glaucoma phenotypes in vivo.

Zhu W, Gramlich OW, Laboissonniere L, Jain A, Sheffield VC, Trimarchi JM, Tucker BA, Kuehn MH.

Proc Natl Acad Sci U S A. 2016 Jun 21;113(25):E3492-500. doi: 10.1073/pnas.1604153113. Epub 2016 Jun 6.


SENP1-modulated sumoylation regulates retinoblastoma protein (RB) and Lamin A/C interaction and stabilization.

Sharma P, Kuehn MR.

Oncogene. 2016 Dec 15;35(50):6429-6438. doi: 10.1038/onc.2016.177. Epub 2016 Jun 6.


Cryopreserved Mesenchymal Stromal Cells Maintain Potency in a Retinal Ischemia/Reperfusion Injury Model: Toward an off-the-shelf Therapy.

Gramlich OW, Burand AJ, Brown AJ, Deutsch RJ, Kuehn MH, Ankrum JA.

Sci Rep. 2016 May 23;6:26463. doi: 10.1038/srep26463.


A Mutation in LTBP2 Causes Congenital Glaucoma in Domestic Cats (Felis catus).

Kuehn MH, Lipsett KA, Menotti-Raymond M, Whitmore SS, Scheetz TE, David VA, O'Brien SJ, Zhao Z, Jens JK, Snella EM, Ellinwood NM, McLellan GJ.

PLoS One. 2016 May 5;11(5):e0154412. doi: 10.1371/journal.pone.0154412. eCollection 2016. Erratum in: PLoS One. 2016;11(8):e0161517.


Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus.

Sohn EH, van Dijk HW, Jiao C, Kok PH, Jeong W, Demirkaya N, Garmager A, Wit F, Kucukevcilioglu M, van Velthoven ME, DeVries JH, Mullins RF, Kuehn MH, Schlingemann RO, Sonka M, Verbraak FD, Abràmoff MD.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2655-64. doi: 10.1073/pnas.1522014113. Epub 2016 Apr 25.


Operating on Genomic Ranges Using BEDOPS.

Neph S, Reynolds AP, Kuehn MS, Stamatoyannopoulos JA.

Methods Mol Biol. 2016;1418:267-81. doi: 10.1007/978-1-4939-3578-9_14.


Parental Consent for Adolescent Research.

Kuehn MB, Hotho D, Prunty M.

Creat Nurs. 2016 Feb 1;22(1):51-55. doi: 10.1891/1078-4535.22.1.51.


Enhancing Clinical Reasoning Through Simulation Debriefing: A Multisite Study.

Forneris SG, Neal DO, Tiffany J, Kuehn MB, Meyer HM, Blazovich LM, Holland AE, Smerillo M.

Nurs Educ Perspect. 2015 Sep-Oct;36(5):304-10.


Genome-Wide Assessment of Outer Membrane Vesicle Production in Escherichia coli.

Kulp AJ, Sun B, Ai T, Manning AJ, Orench-Rivera N, Schmid AK, Kuehn MJ.

PLoS One. 2015 Sep 25;10(9):e0139200. doi: 10.1371/journal.pone.0139200. eCollection 2015.


Adoptive transfer of immune cells from glaucomatous mice provokes retinal ganglion cell loss in recipients.

Gramlich OW, Ding QJ, Zhu W, Cook A, Anderson MG, Kuehn MH.

Acta Neuropathol Commun. 2015 Sep 15;3:56. doi: 10.1186/s40478-015-0234-y.


Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions.

Schwechheimer C, Kuehn MJ.

Nat Rev Microbiol. 2015 Oct;13(10):605-19. doi: 10.1038/nrmicro3525. Review.


Proteomics Analysis of Molecular Risk Factors in the Ocular Hypertensive Human Retina.

Yang X, Hondur G, Li M, Cai J, Klein JB, Kuehn MH, Tezel G.

Invest Ophthalmol Vis Sci. 2015 Sep;56(10):5816-30. doi: 10.1167/iovs.15-17294.


Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma.

Zode GS, Kuehn MH, Nishimura DY, Searby CC, Mohan K, Grozdanic SD, Bugge K, Anderson MG, Clark AF, Stone EM, Sheffield VC.

J Clin Invest. 2015 Aug 3;125(8):3303. doi: 10.1172/JCI82799. Epub 2015 Aug 3. No abstract available.


The genetic mechanisms of primary angle closure glaucoma.

Ahram DF, Alward WL, Kuehn MH.

Eye (Lond). 2015 Oct;29(10):1251-9. doi: 10.1038/eye.2015.124. Epub 2015 Jul 24. Review.


Variants in Nebulin (NEB) Are Linked to the Development of Familial Primary Angle Closure Glaucoma in Basset Hounds.

Ahram DF, Grozdanic SD, Kecova H, Henkes A, Collin RW, Kuehn MH.

PLoS One. 2015 May 4;10(5):e0126660. doi: 10.1371/journal.pone.0126660. eCollection 2015.


NlpI-mediated modulation of outer membrane vesicle production through peptidoglycan dynamics in Escherichia coli.

Schwechheimer C, Rodriguez DL, Kuehn MJ.

Microbiologyopen. 2015 Jun;4(3):375-89. doi: 10.1002/mbo3.244. Epub 2015 Mar 8.


Heterozygous triplication of upstream regulatory sequences leads to dysregulation of matrix metalloproteinase 19 in patients with cavitary optic disc anomaly.

Hazlewood RJ, Roos BR, Solivan-Timpe F, Honkanen RA, Jampol LM, Gieser SC, Meyer KJ, Mullins RF, Kuehn MH, Scheetz TE, Kwon YH, Alward WL, Stone EM, Fingert JH.

Hum Mutat. 2015 Mar;36(3):369-78. doi: 10.1002/humu.22754.


Nodal signaling from the visceral endoderm is required to maintain Nodal gene expression in the epiblast and drive DVE/AVE migration.

Kumar A, Lualdi M, Lyozin GT, Sharma P, Loncarek J, Fu XY, Kuehn MR.

Dev Biol. 2015 Apr 1;400(1):1-9. doi: 10.1016/j.ydbio.2014.12.016. Epub 2014 Dec 20.


Modulation of bacterial outer membrane vesicle production by envelope structure and content.

Schwechheimer C, Kulp A, Kuehn MJ.

BMC Microbiol. 2014 Dec 21;14:324. doi: 10.1186/s12866-014-0324-1.


Induction of trabecular meshwork cells from induced pluripotent stem cells.

Ding QJ, Zhu W, Cook AC, Anfinson KR, Tucker BA, Kuehn MH.

Invest Ophthalmol Vis Sci. 2014 Oct 8;55(11):7065-72. doi: 10.1167/iovs.14-14800.


Immune phenomena in glaucoma and conformational disorders: why is the second eye not involved?

Kuehn MH.

J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S59-61. doi: 10.1097/IJG.0000000000000115. Review.


Isolation of rare recombinants without using selectable markers for one-step seamless BAC mutagenesis.

Lyozin GT, Bressloff PC, Kumar A, Kosaka Y, Demarest BL, Yost HJ, Kuehn MR, Brunelli L.

Nat Methods. 2014 Sep;11(9):966-970. doi: 10.1038/nmeth.3030. Epub 2014 Jul 13.


Identification of genetic loci associated with primary angle-closure glaucoma in the basset hound.

Ahram DF, Cook AC, Kecova H, Grozdanic SD, Kuehn MH.

Mol Vis. 2014 Apr 25;20:497-510. eCollection 2014.


Loss of function of mouse Pax-Interacting Protein 1-associated glutamate rich protein 1a (Pagr1a) leads to reduced Bmp2 expression and defects in chorion and amnion development.

Kumar A, Lualdi M, Loncarek J, Cho YW, Lee JE, Ge K, Kuehn MR.

Dev Dyn. 2014 Jul;243(7):937-47. doi: 10.1002/dvdy.24125. Epub 2014 Apr 17.


Protein selection and export via outer membrane vesicles.

Bonnington KE, Kuehn MJ.

Biochim Biophys Acta. 2014 Aug;1843(8):1612-9. doi: 10.1016/j.bbamcr.2013.12.011. Epub 2013 Dec 24. Review.


Changes in prostaglandin levels in patients undergoing femtosecond laser-assisted cataract surgery.

Schultz T, Joachim SC, Kuehn M, Dick HB.

J Refract Surg. 2013 Nov;29(11):742-7. doi: 10.3928/1081597X-20131021-03.


Immune response against ocular tissues after immunization with optic nerve antigens in a model of autoimmune glaucoma.

Joachim SC, Reinehr S, Kuehn S, Laspas P, Gramlich OW, Kuehn M, Tischoff I, von Pein HD, Dick HB, Grus FH.

Mol Vis. 2013 Aug 6;19:1804-14. eCollection 2013.


Synthetic effect between envelope stress and lack of outer membrane vesicle production in Escherichia coli.

Schwechheimer C, Kuehn MJ.

J Bacteriol. 2013 Sep;195(18):4161-73. doi: 10.1128/JB.02192-12. Epub 2013 Jul 12.


Senp1 is essential for desumoylating Sumo1-modified proteins but dispensable for Sumo2 and Sumo3 deconjugation in the mouse embryo.

Sharma P, Yamada S, Lualdi M, Dasso M, Kuehn MR.

Cell Rep. 2013 May 30;3(5):1640-50. doi: 10.1016/j.celrep.2013.04.016. Epub 2013 May 16.

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