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Items: 1 to 50 of 88

1.

Cyclic AMP-dependent regulation of lipid mediators in white cells. A unifying concept for explaining the efficacy of theophylline in asthma.

Kuehl FA Jr, Zanetti ME, Soderman DD, Miller DK, Ham EA.

Am Rev Respir Dis. 1987 Jul;136(1):210-3. Review.

PMID:
3037956
2.

Endothelial cell prostacyclin production induced by activated neutrophils.

Miller DK, Sadowski S, Soderman DD, Kuehl FA Jr.

J Biol Chem. 1985 Jan 25;260(2):1006-14.

3.

Lung tissue receptors for sulfidopeptide leukotrienes.

Kuehl FA Jr, DeHaven RN, Pong SS.

J Allergy Clin Immunol. 1984 Sep;74(3 Pt 2):378-81.

PMID:
6088614
4.

Interactions between prostaglandins and leukotrienes.

Kuehl FA Jr, Dougherty HW, Ham EA.

Biochem Pharmacol. 1984 Jan 1;33(1):1-5. No abstract available.

PMID:
6322789
5.

Leukotriene C4 binding to rat lung membranes.

Pong SS, DeHaven RN, Kuehl FA Jr, Egan RW.

J Biol Chem. 1983 Aug 25;258(16):9616-9.

6.

Pharmacological effects of non-steroidal antiinflammatory agents on prostaglandin and leukotriene synthesis in mouse peritoneal macrophages.

Humes JL, Sadowski S, Galavage M, Goldenberg M, Subers E, Kuehl FA Jr, Bonney RJ.

Biochem Pharmacol. 1983 Aug 1;32(15):2319-22.

PMID:
6411096
7.

Inhibition by prostaglandins of leukotriene B4 release from activated neutrophils.

Ham EA, Soderman DD, Zanetti ME, Dougherty HW, McCauley E, Kuehl FA Jr.

Proc Natl Acad Sci U S A. 1983 Jul;80(14):4349-53.

8.

Leukotriene A4: preparation and enzymatic conversion in a cell-free system to leukotriene B4.

Maycock AL, Anderson MS, DeSousa DM, Kuehl FA Jr.

J Biol Chem. 1982 Dec 10;257(23):13911-4.

9.

Evidence for two sources of arachidonic acid for oxidative metabolism by mouse peritoneal macrophages.

Humes JL, Sadowski S, Galavage M, Goldenberg M, Subers E, Bonney RJ, Kuehl FA Jr.

J Biol Chem. 1982 Feb 25;257(4):1591-4.

10.

The effect of anti-rheumatic agents on macrophage function.

Davies P, Bonney RJ, Humes JL, Kuehl FA Jr.

Int J Immunopharmacol. 1982;4(2):111-8. Review. No abstract available.

PMID:
7047415
11.

Oxidation reactions by prostaglandin cyclooxygenase-hydroperoxidase.

Egan RW, Gale PH, Baptista EM, Kennicott KL, VandenHeuvel WJ, Walker RW, Fagerness PE, Kuehl FA Jr.

J Biol Chem. 1981 Jul 25;256(14):7352-61.

12.

Multiple sites on prostaglandin cyclooxygenase are determinants in the action of nonsteroidal antiinflammatory agents.

Humes JL, Winter CA, Sadowski SJ, Kuehl FA Jr.

Proc Natl Acad Sci U S A. 1981 Apr;78(4):2053-6.

13.

Mechanism of prostaglandin hydroperoxidase cooxygenation reactions.

Egan RW, Gale PH, Baptista EM, Kuehl FA Jr.

Prog Lipid Res. 1981;20:173-8. No abstract available.

PMID:
7342081
14.

Prostaglandin cyclooxygenase.

Kuehl FA Jr, Egan RW, Humes JL.

Prog Lipid Res. 1981;20:97-102. No abstract available.

PMID:
6804988
15.

Effect of RNA and protein synthesis inhibitors on the release of inflammatory mediators by macrophages responding to phorbol myristate acetate.

Bonney RJ, Wightman PD, Dahlgren ME, Davies P, Kuehl FA Jr, Humes JL.

Biochim Biophys Acta. 1980 Dec 15;633(3):410-21.

PMID:
6894244
16.

Arachidonic acid oxygenation products produced by mouse peritoneal macrophages responding to inflammatory stimuli.

Bonney RJ, Davies P, Kuehl FA Jr, Humes JL.

J Reticuloendothel Soc. 1980 Dec;28(Suppl):113s-115s. Review. No abstract available.

PMID:
7003136
17.

Prostaglandins, arachidonic acid, and inflammation.

Kuehl FA Jr, Egan RW.

Science. 1980 Nov 28;210(4473):978-84. Review.

PMID:
6254151
18.

The role of macrophage secretory products in chronic inflammatory processes.

Davies P, Bonney RJ, Humes JL, Kuehl FA.

J Invest Dermatol. 1980 May;74(5):292-6.

19.

The diminished production of arachidonic acid oxygenation products by elicited mouse peritoneal macrophages: possible mechanisms.

Humes JL, Burger S, Galavage M, Kuehl FA Jr, Wightman PD, Dahlgren ME, Davies P, Bonney RJ.

J Immunol. 1980 May;124(5):2110-6. No abstract available.

PMID:
6245135
20.

Mechanism of oxygen transfer by prostaglandin hydroperoxidase.

Egan RW, Gale PH, VandenHeuvel WJ, Baptista EM, Kuehl FA Jr.

J Biol Chem. 1980 Jan 25;255(2):323-6.

21.

Possible roles of prostaglandins synthesized and secreted by macrophages in regulating immune responses.

Bonney RJ, Davies P, Staruch MJ, Gery I, Kuehl FA, Humes JL.

Agents Actions Suppl. 1980;7:3-9. No abstract available.

PMID:
6972689
22.

Inflammation: the role of peroxidase-derived products.

Kuehl FA Jr, Humes JL, Ham EA, Egan RW, Dougherty HW.

Adv Prostaglandin Thromboxane Res. 1980;6:77-86. No abstract available.

PMID:
6770608
23.

Direct and indirect involvement of radical scavengers during prostaglandin biosynthesis.

Egan RW, Gale PH, Beveridge GC, Marnett LJ, Kuehl FA Jr.

Adv Prostaglandin Thromboxane Res. 1980;6:153-5. No abstract available.

PMID:
6770593
24.

The role of polymorphonuclear peroxidase-dependent oxidants in inflammation.

Dougherty HW, Hen A, Kuehl FA Jr.

Agents Actions Suppl. 1980;7:167-73. No abstract available.

PMID:
6264768
25.

Prostaglandin E2 and prostacyclin elevate cyclic AMP levels in elicited populations of mouse peritoneal macrophages.

Bonney RJ, Burger S, Davies P, Kuehl FA Jr, Humes JL.

Adv Prostaglandin Thromboxane Res. 1980;8:1691-3. No abstract available.

PMID:
6246787
26.

Reduction of hydroperoxides in the prostaglandin biosynthetic pathway by a microsomal peroxidase.

Egan RW, Gale PH, Kuehl FA Jr.

J Biol Chem. 1979 May 10;254(9):3295-302. No abstract available.

27.

Peroxidase-dependent deactivation of prostacyclin synthetase.

Ham EA, Egan RW, Soderman DD, Gale PH, Kuehl FA Jr.

J Biol Chem. 1979 Apr 10;254(7):2191-4.

28.

Evidence for a PGE-receptor in the rat kidney.

Oien HG, Babiarz EM, Soderma DD, Ham EA, Kuehl FA Jr.

Prostaglandins. 1979 Apr;17(4):525-42.

PMID:
223198
29.

Peroxidase reactions during prostaglandin biosynthesis and their relationship to inflammation.

Egan RW, Gale PH, VandenHeuvel WJ, Kuehl FA Jr.

Agents Actions Suppl. 1979;(6):39-49. No abstract available.

PMID:
294147
30.

Macrophages responding to inflammatory stimuli synthesise increased amounts of prostaglandins.

Davies P, Bonney RJ, Humes JL, Kuehl FA Jr.

Agents Actions Suppl. 1979;(6):143-9. No abstract available.

PMID:
294142
31.

Pathways of arachidonic acid metabolism and modulation by drugs.

Humes JL, Ham EA, Egan RW, Bonney RJ, Davies P, Kuehl FA Jr.

Agents Actions Suppl. 1979;(4):96-109.

PMID:
227254
32.

Regulation of prostaglandin synthesis and of the selective release of lysosomal hydrolases by mouse peritoneal macrophages.

Bonney RJ, Wightman PD, Davies P, Sadowski SJ, Kuehl FA Jr, Humes JL.

Biochem J. 1978 Nov 15;176(2):433-42.

33.

11,12-Secoprostaglandins. 5. 8-Acetyl- or 8-(1-hydroxyethyl)-12-hydroxy-13-aryloxytridecanoic acids and sulfonamide isosteres as inhibitors of platelet aggregation.

Bicking JB, Jones JH, Holtz WJ, Robb CH, Kuehl FA Jr, Minsker DH, Cragoe EJ Jr.

J Med Chem. 1978 Oct;21(10):1011-8.

PMID:
214552
34.

Differential effects of prostaglandin synthetase stimulators on inhibition of cyclooxygenase.

Egan RW, Humes JL, Kuehl FA Jr.

Biochemistry. 1978 May 30;17(11):2230-4.

PMID:
96853
35.

Synthesis and release of oxygenation products of arachidonic acid by mononuclear phagocytes in response to inflammatory stimuli.

Davies P, Bonney RJ, Humes JL, Kuehl FA Jr.

Inflammation. 1977 Dec;2(4):335-44. No abstract available.

PMID:
617958
36.

Biologically active derivatives of fatty acids: prostaglandins, thromboxanes, and endoperoxides.

Kuehl FA Jr, Humes JL, Beveridge GC, Van Arman CG, Egan RW.

Inflammation. 1977 Dec;2(4):285-94. Review.

PMID:
370001
37.

Macrophages synthesis and release prostaglandins in response to inflammatory stimuli.

Humes JL, Bonney RJ, Pelus L, Dahlgren ME, Sadowski SJ, Kuehl FA Jr, Davies P.

Nature. 1977 Sep 8;269(5624):149-51. No abstract available.

PMID:
561892
38.

New concepts on the role of prostaglandins in inflammatory processes.

Kuehl FA Jr.

Acta Rhumatol Belg. 1977 Jul-Dec;1(3-4):179-87. No abstract available.

PMID:
116479
39.

11,12-Secoprostaglandins. 3. 8-Alkylthio(sulfinyl and sulfonyl)-12-hydroxyalkanoic acids and related compounds.

Smith RL, Bicking JB, Gould NP, Lee T, Robb CM, Kuehl FA Jr, Mandel LR, Cragoe EJ Jr.

J Med Chem. 1977 Apr;20(4):540-7.

PMID:
191613
40.

Role of prostaglandin endoperoxide PGG2 in inflammatory processes.

Kuehl FA Jr, Humes JL, Egan RW, Ham EA, Beveridge GC, Van Arman CG.

Nature. 1977 Jan 13;265(5590):170-3. No abstract available.

PMID:
834259
41.

11,12-Secoprostaglandins. 2. N-acyl-N-alkyl-7-aminoheptanoic acids.

Jones JH, Holtz WJ, Bicking JB, Cragoe EJ Jr, Mandel LR, Kuehl FA Jr.

J Med Chem. 1977 Jan;20(1):44-8.

PMID:
189029
42.

Mechanism for irreversible self-deactivation of prostaglandin synthetase.

Egan RW, Paxton J, Kuehl FA Jr.

J Biol Chem. 1976 Dec 10;251(23):7329-35.

43.

A 15-hydroxyprostaglandin dehydrogenase specific for prostaglandin A in rabbit kidney.

Oien HG, Ham EA, Zanetti ME, Ulm EH, Kuehl FA Jr.

Proc Natl Acad Sci U S A. 1976 Apr;73(4):1107-11.

44.

The regulatory role of steroid hormones on the PGF/PGE ratio in target tissues.

Kuehl FA Jr, Cirillo VJ, Zanetti ME, Beveridge GC, Ham EA.

Agents Actions. 1976 Feb;6(1-3):165-70.

PMID:
181966
45.

The effect of estrogen upon cyclic nucleotide and prostaglandin levels in the rat uterus.

Kuehl FA Jr, Cirillo VJ, Zanetti ME, Beveridge GC, Ham EA.

Adv Prostaglandin Thromboxane Res. 1976;1:313-23. No abstract available.

PMID:
826144
46.

The reaction of PGA1 with sulfhydryl groups; a component in the binding of A-type prostaglandins to proteins.

Ham EA, Oien HG, Ulm EH, Kuehl FA Jr.

Prostaglandins. 1975 Aug;10(2):217-29.

PMID:
1178903
47.

Estrogen-induced alterations in cyclic nucleotide and prostaglandin levels in target tissue.

Kuehl FA Jr, Zanetti ME, Cirillo VJ, Ham EA.

J Steroid Biochem. 1975 Jun;6(6):1099-105. No abstract available.

PMID:
170459
48.

Structural requirements for the binding of prostaglandins.

Oien HG, Mandel LR, Humes JL, Taub D, Hoffsommer RD, Kuehl FA Jr.

Prostaglandins. 1975 Jun;9(6):985-95.

PMID:
169553
49.

Estrogen-directed synthesis of specific prostaglandins in uterus.

Ham EA, Cirillo VJ, Zanetti ME, Kuehl FA Jr.

Proc Natl Acad Sci U S A. 1975 Apr;72(4):1420-4.

50.

Biologic regulation through opposing influences of cyclic GMP and cyclic AMP: the Yin Yang hypothesis.

Goldberg ND, Haddox MK, Nicol SE, Glass DB, Sanford CH, Kuehl FA Jr, Estensen R.

Adv Cyclic Nucleotide Res. 1975;5:307-30. Review. No abstract available.

PMID:
165672

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