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Items: 33

1.

Linear mitochondrial DNA is rapidly degraded by components of the replication machinery.

Peeva V, Blei D, Trombly G, Corsi S, Szukszto MJ, Rebelo-Guiomar P, Gammage PA, Kudin AP, Becker C, Altmüller J, Minczuk M, Zsurka G, Kunz WS.

Nat Commun. 2018 Apr 30;9(1):1727. doi: 10.1038/s41467-018-04131-w.

2.

Mitochondrial Liver Toxicity of Valproic Acid and Its Acid Derivatives Is Related to Inhibition of α-Lipoamide Dehydrogenase.

Kudin AP, Mawasi H, Eisenkraft A, Elger CE, Bialer M, Kunz WS.

Int J Mol Sci. 2017 Sep 6;18(9). pii: E1912. doi: 10.3390/ijms18091912.

3.

Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy.

Kudin AP, Baron G, Zsurka G, Hampel KG, Elger CE, Grote A, Weber Y, Lerche H, Thiele H, Nürnberg P, Schulz H, Ruppert AK, Sander T, Cheng Q, Arnér ES, Schomburg L, Seeher S, Fradejas-Villar N, Schweizer U, Kunz WS.

Free Radic Biol Med. 2017 May;106:270-277. doi: 10.1016/j.freeradbiomed.2017.02.040. Epub 2017 Feb 21.

PMID:
28232204
4.

Loss of the smallest subunit of cytochrome c oxidase, COX8A, causes Leigh-like syndrome and epilepsy.

Hallmann K, Kudin AP, Zsurka G, Kornblum C, Reimann J, Stüve B, Waltz S, Hattingen E, Thiele H, Nürnberg P, Rüb C, Voos W, Kopatz J, Neumann H, Kunz WS.

Brain. 2016 Feb;139(Pt 2):338-45. doi: 10.1093/brain/awv357. Epub 2015 Dec 17.

PMID:
26685157
5.

Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity.

Kukat A, Dogan SA, Edgar D, Mourier A, Jacoby C, Maiti P, Mauer J, Becker C, Senft K, Wibom R, Kudin AP, Hultenby K, Flögel U, Rosenkranz S, Ricquier D, Kunz WS, Trifunovic A.

PLoS Genet. 2014 Jun 19;10(6):e1004385. doi: 10.1371/journal.pgen.1004385. eCollection 2014 Jun.

6.

Hemin inhibits the large conductance potassium channel in brain mitochondria: a putative novel mechanism of neurodegeneration.

Augustynek B, Kudin AP, Bednarczyk P, Szewczyk A, Kunz WS.

Exp Neurol. 2014 Jul;257:70-5. doi: 10.1016/j.expneurol.2014.04.022. Epub 2014 Apr 30.

PMID:
24792919
7.

Microglial CD33-related Siglec-E inhibits neurotoxicity by preventing the phagocytosis-associated oxidative burst.

Claude J, Linnartz-Gerlach B, Kudin AP, Kunz WS, Neumann H.

J Neurosci. 2013 Nov 13;33(46):18270-6. doi: 10.1523/JNEUROSCI.2211-13.2013.

8.

Mitofusin 2 mutations affect mitochondrial function by mitochondrial DNA depletion.

Vielhaber S, Debska-Vielhaber G, Peeva V, Schoeler S, Kudin AP, Minin I, Schreiber S, Dengler R, Kollewe K, Zuschratter W, Kornblum C, Zsurka G, Kunz WS.

Acta Neuropathol. 2013 Feb;125(2):245-56. doi: 10.1007/s00401-012-1036-y. Epub 2012 Aug 28.

PMID:
22926664
9.

The contribution of thioredoxin-2 reductase and glutathione peroxidase to H(2)O(2) detoxification of rat brain mitochondria.

Kudin AP, Augustynek B, Lehmann AK, Kovács R, Kunz WS.

Biochim Biophys Acta. 2012 Oct;1817(10):1901-6. doi: 10.1016/j.bbabio.2012.02.023. Epub 2012 Feb 28.

10.

Changes in mitochondrial reactive oxygen species synthesis during differentiation of skeletal muscle cells.

Malinska D, Kudin AP, Bejtka M, Kunz WS.

Mitochondrion. 2012 Jan;12(1):144-8. doi: 10.1016/j.mito.2011.06.015. Epub 2011 Jul 20.

PMID:
21782978
11.

Complex III-dependent superoxide production of brain mitochondria contributes to seizure-related ROS formation.

Malinska D, Kulawiak B, Kudin AP, Kovacs R, Huchzermeyer C, Kann O, Szewczyk A, Kunz WS.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1163-70. doi: 10.1016/j.bbabio.2010.03.001. Epub 2010 Mar 6.

12.

Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration.

Gispert S, Ricciardi F, Kurz A, Azizov M, Hoepken HH, Becker D, Voos W, Leuner K, Müller WE, Kudin AP, Kunz WS, Zimmermann A, Roeper J, Wenzel D, Jendrach M, García-Arencíbia M, Fernández-Ruiz J, Huber L, Rohrer H, Barrera M, Reichert AS, Rüb U, Chen A, Nussbaum RL, Auburger G.

PLoS One. 2009 Jun 3;4(6):e5777. doi: 10.1371/journal.pone.0005777.

13.

Calcium ions regulate K⁺ uptake into brain mitochondria: the evidence for a novel potassium channel.

Skalska J, Bednarczyk P, Piwońska M, Kulawiak B, Wilczynski G, Dołowy K, Kudin AP, Kunz WS, Szewczyk A.

Int J Mol Sci. 2009 Mar;10(3):1104-20. doi: 10.3390/ijms10031104. Epub 2009 Mar 12.

14.

Chapter 23 Quantification of superoxide production by mouse brain and skeletal muscle mitochondria.

Malinska D, Kudin AP, Debska-Vielhaber G, Vielhaber S, Kunz WS.

Methods Enzymol. 2009;456:419-37. doi: 10.1016/S0076-6879(08)04423-6.

PMID:
19348902
15.

Mitochondrial involvement in temporal lobe epilepsy.

Kudin AP, Zsurka G, Elger CE, Kunz WS.

Exp Neurol. 2009 Aug;218(2):326-32. doi: 10.1016/j.expneurol.2009.02.014. Epub 2009 Mar 5. Review.

PMID:
19268667
16.

BK channel openers inhibit ROS production of isolated rat brain mitochondria.

Kulawiak B, Kudin AP, Szewczyk A, Kunz WS.

Exp Neurol. 2008 Aug;212(2):543-7. doi: 10.1016/j.expneurol.2008.05.004. Epub 2008 May 20.

PMID:
18572168
17.

Sites of generation of reactive oxygen species in homogenates of brain tissue determined with the use of respiratory substrates and inhibitors.

Kudin AP, Malinska D, Kunz WS.

Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):689-95. doi: 10.1016/j.bbabio.2008.05.010. Epub 2008 May 24.

18.

Mitochondrial dysfunction in neurodegenerative disorders.

Baron M, Kudin AP, Kunz WS.

Biochem Soc Trans. 2007 Nov;35(Pt 5):1228-31. Review.

PMID:
17956319
19.

Subfield-specific loss of hippocampal N-acetyl aspartate in temporal lobe epilepsy.

Vielhaber S, Niessen HG, Debska-Vielhaber G, Kudin AP, Wellmer J, Kaufmann J, Schönfeld MA, Fendrich R, Willker W, Leibfritz D, Schramm J, Elger CE, Heinze HJ, Kunz WS.

Epilepsia. 2008 Jan;49(1):40-50. Epub 2007 Sep 5.

20.

Human epidermal keratinocytes accumulate superoxide due to low activity of Mn-SOD, leading to mitochondrial functional impairment.

Hornig-Do HT, von Kleist-Retzow JC, Lanz K, Wickenhauser C, Kudin AP, Kunz WS, Wiesner RJ, Schauen M.

J Invest Dermatol. 2007 May;127(5):1084-93. Epub 2006 Dec 21.

21.

Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6.

Hoepken HH, Gispert S, Morales B, Wingerter O, Del Turco D, Mülsch A, Nussbaum RL, Müller K, Dröse S, Brandt U, Deller T, Wirth B, Kudin AP, Kunz WS, Auburger G.

Neurobiol Dis. 2007 Feb;25(2):401-11. Epub 2006 Nov 30.

PMID:
17141510
22.

Amelioration of water maze performance deficits by topiramate applied during pilocarpine-induced status epilepticus is negatively dose-dependent.

Frisch C, Kudin AP, Elger CE, Kunz WS, Helmstaedter C.

Epilepsy Res. 2007 Feb;73(2):173-80. Epub 2006 Nov 2.

PMID:
17084066
23.

Characterization of superoxide production sites in isolated rat brain and skeletal muscle mitochondria.

Kudin AP, Debska-Vielhaber G, Kunz WS.

Biomed Pharmacother. 2005 May;59(4):163-8. Epub 2005 Mar 22.

PMID:
15862710
24.

The mechanism of neuroprotection by topiramate in an animal model of epilepsy.

Kudin AP, Debska-Vielhaber G, Vielhaber S, Elger CE, Kunz WS.

Epilepsia. 2004 Dec;45(12):1478-87.

25.

The role of mitochondria in epilepsy: implications for neurodegenerative diseases.

Kunz WS, Bimpong-Buta NY, Kudin AP, Elger CE.

Toxicol Mech Methods. 2004;14(1-2):19-23. doi: 10.1080/15376520490257374.

PMID:
20021117
26.

Characterization of superoxide-producing sites in isolated brain mitochondria.

Kudin AP, Bimpong-Buta NY, Vielhaber S, Elger CE, Kunz WS.

J Biol Chem. 2004 Feb 6;279(6):4127-35. Epub 2003 Nov 18.

27.

Hippocampal N-acetyl aspartate levels do not mirror neuronal cell densities in creatine-supplemented epileptic rats.

Vielhaber S, Kudin AP, Kudina TA, Stiller D, Scheich H, Schoenfeld A, Feistner H, Heinze HJ, Elger CE, Kunz WS.

Eur J Neurosci. 2003 Oct;18(8):2292-300.

PMID:
14622190
28.

Metabolic consequences of a novel missense mutation of the mtDNA CO I gene.

Varlamov DA, Kudin AP, Vielhaber S, Schröder R, Sassen R, Becker A, Kunz D, Haug K, Rebstock J, Heils A, Elger CE, Kunz WS.

Hum Mol Genet. 2002 Aug 1;11(16):1797-805.

PMID:
12140182
29.

Seizure-dependent modulation of mitochondrial oxidative phosphorylation in rat hippocampus.

Kudin AP, Kudina TA, Seyfried J, Vielhaber S, Beck H, Elger CE, Kunz WS.

Eur J Neurosci. 2002 Apr;15(7):1105-14.

PMID:
11982622
30.

Mitochondrial complex I deficiency in the epileptic focus of patients with temporal lobe epilepsy.

Kunz WS, Kudin AP, Vielhaber S, Blümcke I, Zuschratter W, Schramm J, Beck H, Elger CE.

Ann Neurol. 2000 Nov;48(5):766-73.

PMID:
11079540
31.
32.

Calcium binding to polypeptides of rat liver and Zajdela hepatoma mitochondrial inner membranes.

Evtodienko YV, Azarashvili TS, Kudin AP.

FEBS Lett. 1998 Feb 13;423(1):45-8.

33.

Polypeptide composition of submitochondrial fractions of normal liver tissue and Zajdela hepatoma.

Azarashvili TS, Kudin AP, Polteva NA, Kudzina LYu, Evtodienko YuV.

Biochemistry (Mosc). 1997 Jul;62(7):710-7.

PMID:
9331962

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