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Items: 12

1.

3-Deoxyschweinfurthin B Lowers Cholesterol Levels by Decreasing Synthesis and Increasing Export in Cultured Cancer Cell Lines.

Kuder CH, Weivoda MM, Zhang Y, Zhu J, Neighbors JD, Wiemer DF, Hohl RJ.

Lipids. 2015 Dec;50(12):1195-207. doi: 10.1007/s11745-015-4083-z. Epub 2015 Oct 22.

2.

Calcium and P-glycoprotein independent synergism between schweinfurthins and verapamil.

Sheehy RM, Kuder CH, Bachman Z, Hohl RJ.

Cancer Biol Ther. 2015;16(8):1259-68. doi: 10.1080/15384047.2015.1056420. Epub 2015 Jun 5.

3.

In vitro studies in a myelogenous leukemia cell line suggest an organized binding of geranylgeranyl diphosphate synthase inhibitors.

Reilly JE, Zhou X, Tong H, Kuder CH, Wiemer DF, Hohl RJ.

Biochem Pharmacol. 2015 Jul 15;96(2):83-92. doi: 10.1016/j.bcp.2015.04.009. Epub 2015 May 4.

4.

Quantitative determination of isopentenyl diphosphate in cultured mammalian cells.

Tong H, Kuder CH, Wasko BM, Hohl RJ.

Anal Biochem. 2013 Feb 1;433(1):36-42. doi: 10.1016/j.ab.2012.09.001. Epub 2012 Sep 19.

PMID:
23000003
5.

Functional evaluation of a fluorescent schweinfurthin: mechanism of cytotoxicity and intracellular quantification.

Kuder CH, Sheehy RM, Neighbors JD, Wiemer DF, Hohl RJ.

Mol Pharmacol. 2012 Jul;82(1):9-16. doi: 10.1124/mol.111.077107. Epub 2012 Mar 29.

6.

Pleiotropic effects of a schweinfurthin on isoprenoid homeostasis.

Holstein SA, Kuder CH, Tong H, Hohl RJ.

Lipids. 2011 Oct;46(10):907-21. doi: 10.1007/s11745-011-3572-y. Epub 2011 Jun 2.

7.

Biologically active biotin derivatives of schweinfurthin F.

Ulrich NC, Kuder CH, Hohl RJ, Wiemer DF.

Bioorg Med Chem Lett. 2010 Nov 15;20(22):6716-20. doi: 10.1016/j.bmcl.2010.08.143. Epub 2010 Sep 6.

PMID:
20869871
8.

Fluorescent schweinfurthin B and F analogs with anti-proliferative activity.

Topczewski JJ, Kuder CH, Neighbors JD, Hohl RJ, Wiemer DF.

Bioorg Med Chem. 2010 Sep 15;18(18):6734-41. doi: 10.1016/j.bmc.2010.07.056. Epub 2010 Jul 29.

9.

Structural analogues of schweinfurthin F: probing the steric, electronic, and hydrophobic properties of the D-ring substructure.

Ulrich NC, Kodet JG, Mente NR, Kuder CH, Beutler JA, Hohl RJ, Wiemer DF.

Bioorg Med Chem. 2010 Feb 15;18(4):1676-83. doi: 10.1016/j.bmc.2009.12.063. Epub 2010 Jan 4.

10.

Quantitative determination of geranyl diphosphate levels in cultured human cells.

Holstein SA, Tong H, Kuder CH, Hohl RJ.

Lipids. 2009 Nov;44(11):1055-62. doi: 10.1007/s11745-009-3355-x. Epub 2009 Oct 24.

PMID:
19856009
11.

Synthesis and biological activity of a fluorescent schweinfurthin analogue.

Kuder CH, Neighbors JD, Hohl RJ, Wiemer DF.

Bioorg Med Chem. 2009 Jul 1;17(13):4718-23. doi: 10.1016/j.bmc.2009.04.071. Epub 2009 May 6.

PMID:
19464190
12.

Synthesis of fluorescently tagged isoprenoid bisphosphonates that inhibit protein geranylgeranylation.

Maalouf MA, Wiemer AJ, Kuder CH, Hohl RJ, Wiemer DF.

Bioorg Med Chem. 2007 Mar 1;15(5):1959-66. Epub 2007 Jan 4.

PMID:
17254791

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