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Items: 1 to 50 of 98

1.

p19-Targeting ILP Protein Blockers of IL-23/Th-17 Pro-Inflammatory Axis Displayed on Engineered Bacteria of Food Origin.

Škrlec K, Zadravec P, Hlavničková M, Kuchař M, Vaňková L, Petroková H, Křížová L, Černý J, Berlec A, Malý P.

Int J Mol Sci. 2018 Jul 1;19(7). pii: E1933. doi: 10.3390/ijms19071933.

2.

Evaluation of Fluorine-18-Labeled α1(I)-N-Telopeptide Analogs as Substrate-Based Radiotracers for PET Imaging of Melanoma-Associated Lysyl Oxidase.

Kuchar M, Neuber C, Belter B, Bergmann R, Lenk J, Wodtke R, Kniess T, Steinbach J, Pietzsch J, Löser R.

Front Chem. 2018 Apr 26;6:121. doi: 10.3389/fchem.2018.00121. eCollection 2018.

3.

Behavioural, Pharmacokinetic, Metabolic, and Hyperthermic Profile of 3,4-Methylenedioxypyrovalerone (MDPV) in the Wistar Rat.

Horsley RR, Lhotkova E, Hajkova K, Feriancikova B, Himl M, Kuchar M, Páleníček T.

Front Psychiatry. 2018 Apr 24;9:144. doi: 10.3389/fpsyt.2018.00144. eCollection 2018.

4.

Sensitive enzyme immunoassay for screening methandienone in dietary supplements.

Sýkorová S, Fojtíková L, Kuchař M, Mikšátková P, Karamonová L, Fukal L, Lapčík O, Holubová B.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Sep;35(9):1653-1661. doi: 10.1080/19440049.2018.1459876. Epub 2018 Jul 25.

PMID:
29601260
5.

Structure determination of butylone as a new psychoactive substance using chiroptical and vibrational spectroscopies.

Spálovská D, Králík F, Kohout M, Jurásek B, Habartová L, Kuchař M, Setnička V.

Chirality. 2018 May;30(5):548-559. doi: 10.1002/chir.22825. Epub 2018 Feb 9.

PMID:
29424468
6.

Chiroptical and vibrational spectroscopic study of genuine and counterfeit medicines containing tadalafil.

Králík F, Jirmásek P, Kuchař M, Setnička V.

Chirality. 2018 May;30(5):560-567. doi: 10.1002/chir.22828. Epub 2018 Feb 8.

PMID:
29419887
7.

Mephedrone (4-Methylmethcathinone): Acute Behavioral Effects, Hyperthermic, and Pharmacokinetic Profile in Rats.

Šíchová K, Pinterová N, Židková M, Horsley RR, Lhotková E, Štefková K, Vejmola Č, Uttl L, Balíková M, Kuchař M, Páleníček T.

Front Psychiatry. 2018 Jan 10;8:306. doi: 10.3389/fpsyt.2017.00306. eCollection 2017.

8.

Lateral flow immunoassay and enzyme linked immunosorbent assay as effective immunomethods for the detection of synthetic cannabinoid JWH-200 based on the newly synthesized hapten.

Fojtíková L, Šuláková A, Blažková M, Holubová B, Kuchař M, Mikšátková P, Lapčík O, Fukal L.

Toxicol Rep. 2017 Dec 6;5:65-75. doi: 10.1016/j.toxrep.2017.12.004. eCollection 2018.

9.

Plectin controls biliary tree architecture and stability in cholestasis.

Jirouskova M, Nepomucka K, Oyman-Eyrilmez G, Kalendova A, Havelkova H, Sarnova L, Chalupsky K, Schuster B, Benada O, Miksatkova P, Kuchar M, Fabian O, Sedlacek R, Wiche G, Gregor M.

J Hepatol. 2018 May;68(5):1006-1017. doi: 10.1016/j.jhep.2017.12.011. Epub 2017 Dec 20.

PMID:
29273475
10.

Pharmacokinetic, Ambulatory, and Hyperthermic Effects of 3,4-Methylenedioxy-N-Methylcathinone (Methylone) in Rats.

Štefková K, Židková M, Horsley RR, Pinterová N, Šíchová K, Uttl L, Balíková M, Danda H, Kuchař M, Páleníček T.

Front Psychiatry. 2017 Nov 17;8:232. doi: 10.3389/fpsyt.2017.00232. eCollection 2017.

11.

Pharmacokinetic and behavioural profile of THC, CBD, and THC+CBD combination after pulmonary, oral, and subcutaneous administration in rats and confirmation of conversion in vivo of CBD to THC.

Hložek T, Uttl L, Kadeřábek L, Balíková M, Lhotková E, Horsley RR, Nováková P, Šíchová K, Štefková K, Tylš F, Kuchař M, Páleníček T.

Eur Neuropsychopharmacol. 2017 Dec;27(12):1223-1237. doi: 10.1016/j.euroneuro.2017.10.037. Epub 2017 Nov 10.

PMID:
29129557
12.

Reply to Comments by Pescitelli and Bruhn on "Cocaine Hydrochloride Structure in Solution Revealed by Three Chiroptical Methods".

Fagan P, Kocourková L, Tatarkovič M, Králík F, Kuchař M, Setnička V, Bouř P.

Chemphyschem. 2017 Sep 20;18(18):2552. doi: 10.1002/cphc.201700850. Epub 2017 Aug 23. No abstract available.

PMID:
28834612
13.

Cocaine Hydrochloride Structure in Solution Revealed by Three Chiroptical Methods.

Fagan P, Kocourková L, Tatarkovič M, Králík F, Kuchař M, Setnička V, Bouř P.

Chemphyschem. 2017 Aug 18;18(16):2258-2265. doi: 10.1002/cphc.201700452. Epub 2017 Jul 7.

PMID:
28685956
14.

Individual prolactin reactivity modulates response of nucleus accumbens to erotic stimuli during acute cannabis intoxication: an fMRI pilot study.

Androvicova R, Horacek J, Tintera J, Hlinka J, Rydlo J, Jezova D, Balikova M, Hlozek T, Miksatkova P, Kuchar M, Roman M, Tomicek P, Tyls F, Viktorinova M, Palenicek T.

Psychopharmacology (Berl). 2017 Jul;234(13):1933-1943. doi: 10.1007/s00213-017-4601-1. Epub 2017 Apr 12.

PMID:
28401285
15.

p19-targeted ABD-derived protein variants inhibit IL-23 binding and exert suppressive control over IL-23-stimulated expansion of primary human IL-17+ T-cells.

Křížová L, Kuchař M, Petroková H, Osička R, Hlavničková M, Pelák O, Černý J, Kalina T, Malý P.

Autoimmunity. 2017 Mar;50(2):102-113. doi: 10.1080/08916934.2016.1272598. Epub 2017 Jan 19.

PMID:
28100093
16.

Highly sensitive avidin-biotin ELISA for detection of nandrolone and testosterone in dietary supplements.

Jurášek M, Göselová S, Mikšátková P, Holubová B, Vyšatová E, Kuchař M, Fukal L, Lapčík O, Drašar P.

Drug Test Anal. 2017 Apr;9(4):553-560. doi: 10.1002/dta.2005. Epub 2016 Jul 1.

PMID:
27367148
17.

Efficiency and stability of spectral sensitization of boron-doped-diamond electrodes through covalent anchoring of a donor-acceptor organic chromophore (P1).

Krysova H, Barton J, Petrak V, Jurok R, Kuchar M, Cigler P, Kavan L.

Phys Chem Chem Phys. 2016 Jun 28;18(24):16444-50. doi: 10.1039/c6cp02209j. Epub 2016 Jun 6.

PMID:
27264474
18.

Detailed pharmacological evaluation of methoxetamine (MXE), a novel psychoactive ketamine analogue-Behavioural, pharmacokinetic and metabolic studies in the Wistar rat.

Horsley RR, Lhotkova E, Hajkova K, Jurasek B, Kuchar M, Palenicek T.

Brain Res Bull. 2016 Sep;126(Pt 1):102-110. doi: 10.1016/j.brainresbull.2016.05.002. Epub 2016 May 4. Review.

PMID:
27155360
19.

Emerging toxicity of 5,6-methylenedioxy-2-aminoindane (MDAI): Pharmacokinetics, behaviour, thermoregulation and LD50 in rats.

Páleníček T, Lhotková E, Žídková M, Balíková M, Kuchař M, Himl M, Mikšátková P, Čegan M, Valeš K, Tylš F, Horsley RR.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Aug 1;69:49-59. doi: 10.1016/j.pnpbp.2016.04.004. Epub 2016 Apr 12.

PMID:
27083855
20.

Chiral separation of new designer drugs (Cathinones) on chiral ion-exchange type stationary phases.

Wolrab D, Frühauf P, Moulisová A, Kuchař M, Gerner C, Lindner W, Kohout M.

J Pharm Biomed Anal. 2016 Feb 20;120:306-15. doi: 10.1016/j.jpba.2015.12.023. Epub 2015 Dec 24.

PMID:
26765268
21.

Biocompatible Size-Defined Dendrimer-Albumin Binding Protein Hybrid Materials as a Versatile Platform for Biomedical Applications.

Maly J, Stanek O, Frolik J, Maly M, Ennen F, Appelhans D, Semeradtova A, Wrobel D, Stofik M, Knapova T, Kuchar M, Stastna LC, Cermak J, Sebo P, Maly P.

Macromol Biosci. 2016 Apr;16(4):553-66. doi: 10.1002/mabi.201500332. Epub 2016 Jan 8.

PMID:
26748571
22.

Salting-out-assisted liquid-liquid extraction as a suitable approach for determination of methoxetamine in large sets of tissue samples.

Hajkova K, Jurasek B, Sykora D, Palenicek T, Miksatkova P, Kuchar M.

Anal Bioanal Chem. 2016 Feb;408(4):1171-81. doi: 10.1007/s00216-015-9221-1. Epub 2015 Dec 11.

PMID:
26661068
23.

Methods to Increase the Metabolic Stability of (18)F-Radiotracers.

Kuchar M, Mamat C.

Molecules. 2015 Sep 3;20(9):16186-220. doi: 10.3390/molecules200916186. Review.

24.

Targeting lysyl oxidase for molecular imaging in breast cancer.

Wuest M, Kuchar M, Sharma SK, Richter S, Hamann I, Wang M, Vos L, Mackey JR, Wuest F, Löser R.

Breast Cancer Res. 2015 Aug 13;17:107. doi: 10.1186/s13058-015-0609-9.

25.

Novel binders derived from an albumin-binding domain scaffold targeting human prostate secretory protein 94 (PSP94).

Marečková L, Petroková H, Osička R, Kuchař M, Malý P.

Protein Cell. 2015 Oct;6(10):774-9. doi: 10.1007/s13238-015-0194-9. No abstract available.

26.

Cyclopeptides containing the DEKS motif as conformationally restricted collagen telopeptide analogues: synthesis and conformational analysis.

Wodtke R, Ruiz-Gómez G, Kuchar M, Pisabarro MT, Novotná P, Urbanová M, Steinbach J, Pietzsch J, Löser R.

Org Biomol Chem. 2015 Feb 14;13(6):1878-96. doi: 10.1039/c4ob02348j.

PMID:
25503999
27.

A new strategy for the surgical management of RLN infiltrated by well-differentiated thyroid carcinoma.

Boucek J, Zabrodsky M, Kuchar M, Fanta O, Skrivan J, Betka J.

Biomed Res Int. 2014;2014:616521. doi: 10.1155/2014/616521. Epub 2014 May 14.

28.

Human interleukin-23 receptor antagonists derived from an albumin-binding domain scaffold inhibit IL-23-dependent ex vivo expansion of IL-17-producing T-cells.

Kuchař M, Vaňková L, Petroková H, Cerný J, Osička R, Pelák O, Sípová H, Schneider B, Homola J, Sebo P, Kalina T, Malý P.

Proteins. 2014 Jun;82(6):975-89. doi: 10.1002/prot.24472. Epub 2013 Nov 23.

29.

Increasing affinity of interferon-γ receptor 1 to interferon-γ by computer-aided design.

Mikulecký P, Cerný J, Biedermannová L, Petroková H, Kuchař M, Vondrášek J, Malý P, Šebo P, Schneider B.

Biomed Res Int. 2013;2013:752514. doi: 10.1155/2013/752514. Epub 2013 Oct 2.

30.

Synthesis and radiopharmacological characterisation of a fluorine-18-labelled azadipeptide nitrile as a potential PET tracer for in vivo imaging of cysteine cathepsins.

Löser R, Bergmann R, Frizler M, Mosch B, Dombrowski L, Kuchar M, Steinbach J, Gütschow M, Pietzsch J.

ChemMedChem. 2013 Aug;8(8):1330-44. doi: 10.1002/cmdc.201300135. Epub 2013 Jun 19.

PMID:
23785011
31.

An efficient bioorthogonal strategy using CuAAC click chemistry for radiofluorinations of SNEW peptides and the role of copper depletion.

Pretze M, Kuchar M, Bergmann R, Steinbach J, Pietzsch J, Mamat C.

ChemMedChem. 2013 Jun;8(6):935-45. doi: 10.1002/cmdc.201300053. Epub 2013 Apr 4.

PMID:
23559494
32.

Immediate revision in patients with bilateral recurrent laryngeal nerve palsy after thyroid and parathyroid surgery. How worthy is it?

Zábrodský M, Bouček J, Kastner J, Kuchař M, Chovanec M, Betka J.

Acta Otorhinolaryngol Ital. 2012 Aug;32(4):222-8.

33.

Radioiodinated sunitinib as a potential radiotracer for imaging angiogenesis-radiosynthesis and first radiopharmacological evaluation of 5-[125I]Iodo-sunitinib.

Kuchar M, Oliveira MC, Gano L, Santos I, Kniess T.

Bioorg Med Chem Lett. 2012 Apr 15;22(8):2850-5. doi: 10.1016/j.bmcl.2012.02.068. Epub 2012 Mar 1.

PMID:
22444679
34.

Site-selective radiolabeling of peptides by (18)F-fluorobenzoylation with [(18F)]SFB in solution and on solid phase: a comparative study.

Kuchar M, Pretze M, Kniess T, Steinbach J, Pietzsch J, Löser R.

Amino Acids. 2012 Oct;43(4):1431-43.

PMID:
22302364
35.

Novel high-affinity binders of human interferon gamma derived from albumin-binding domain of protein G.

Ahmad JN, Li J, Biedermannová L, Kuchař M, Sípová H, Semerádtová A, Cerný J, Petroková H, Mikulecký P, Polínek J, Staněk O, Vondrášek J, Homola J, Malý J, Osička R, Sebo P, Malý P.

Proteins. 2012 Mar;80(3):774-89. doi: 10.1002/prot.23234. Epub 2011 Nov 24.

PMID:
22113774
36.

Automated radiosynthesis of the thiol-reactive labeling agent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide ([18F]FBAM).

Kniess T, Kuchar M, Pietzsch J.

Appl Radiat Isot. 2011 Sep;69(9):1226-30. doi: 10.1016/j.apradiso.2011.03.043. Epub 2011 Apr 8.

PMID:
21507666
37.

Synthesis and radiopharmacological investigation of 3-[4'-[(18)F]fluorobenzylidene]indolin-2-one as possible tyrosine kinase inhibitor.

Kniess T, Bergmann R, Kuchar M, Steinbach J, Wuest F.

Bioorg Med Chem. 2009 Nov 15;17(22):7732-42. doi: 10.1016/j.bmc.2009.09.038. Epub 2009 Sep 25.

PMID:
19822433
38.

Age and sexually dimorphic changes in costal cartilages. A preliminary microscopic study.

Rejtarová O, Hejna P, Soukup T, Kuchar M.

Forensic Sci Int. 2009 Dec 15;193(1-3):72-8. doi: 10.1016/j.forsciint.2009.09.009. Epub 2009 Oct 12.

PMID:
19819654
39.

Regulatory T cells and their prognostic value for patients with squamous cell carcinoma of the head and neck.

Boucek J, Mrkvan T, Chovanec M, Kuchar M, Betka J, Boucek V, Hladikova M, Betka J, Eckschlager T, Rihova B.

J Cell Mol Med. 2010 Jan;14(1-2):426-33. doi: 10.1111/j.1582-4934.2008.00650.x. Epub 2009 Jan 14.

40.

The influence of leukotriene receptors' antagonists on experimentally induced ulcer in rats.

Cuciureanu M, Căruntu ID, Kuchar M, Nechifor M.

Rev Med Chir Soc Med Nat Iasi. 2008 Jul-Sep;112(3):750-6.

PMID:
20201264
41.

Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations.

Kuchar M, Pohl R, Klepetárová B, Votruba I, Hocek M.

Org Biomol Chem. 2008 Jul 7;6(13):2377-87. doi: 10.1039/b802833h. Epub 2008 May 2.

PMID:
18563272
42.

Antileukotrienic phenethylamido derivatives of arylalkanoic acids in the treatment of ulcerative colitis.

Junek R, Kverka M, Jandera A, Panajotová V, Satinský D, Machácek M, Kuchar M.

Eur J Med Chem. 2009 Jan;44(1):332-44. doi: 10.1016/j.ejmech.2008.02.030. Epub 2008 Mar 7.

PMID:
18406012
43.

Mapping of interaction domains of putative telomere-binding proteins AtTRB1 and AtPOT1b from Arabidopsis thaliana.

Schrumpfová PP, Kuchar M, Palecek J, Fajkus J.

FEBS Lett. 2008 Apr 30;582(10):1400-6. doi: 10.1016/j.febslet.2008.03.034. Epub 2008 Apr 1.

44.

Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides.

Kuchar M, Hocek M, Pohl R, Votruba I, Shih IH, Mabery E, Mackman R.

Bioorg Med Chem. 2008 Feb 1;16(3):1400-24. Epub 2007 Oct 23.

PMID:
17997319
45.

Antileukotrienic N-arylethyl-2-arylacetamides in the treatment of ulcerative colitis.

Junek R, Brůnová B, Kverka M, Panajotová V, Jandera A, Kuchar M.

Eur J Med Chem. 2007 Aug;42(8):1084-94. Epub 2007 Jan 27.

PMID:
17448575
46.

Magnetic resonance imaging of the rat brain after epileptic seizures--preliminary results.

Kuchar MZ, Jerábková P, Brada J, Kaspar J, Skrivan J, Betka J, Langmeier M.

Prague Med Rep. 2006;107(2):242-50.

PMID:
17066743
47.

Pharmacological profile of 4-(2',4'-difluorobiphenyl-4-yl)-2-methylbutyric acid (deoxoflobufen).

Bulej P, Kuchar M, Panajotova V, Jegorov A.

Arzneimittelforschung. 2005;55(8):466-72.

PMID:
16149715
49.

Characterization of two Arabidopsis thaliana myb-like proteins showing affinity to telomeric DNA sequence.

Schrumpfová P, Kuchar M, Miková G, Skrísovská L, Kubicárová T, Fajkus J.

Genome. 2004 Apr;47(2):316-24.

PMID:
15060584
50.

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