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Items: 1 to 50 of 64

1.

Blueberry metabolites restore cell surface glycosaminoglycans and attenuate endothelial inflammation in diabetic human aortic endothelial cells.

Cutler BR, Gholami S, Chua JS, Kuberan B, Anandh Babu PV.

Int J Cardiol. 2018 Jun 15;261:155-158. doi: 10.1016/j.ijcard.2018.03.027. Epub 2018 Mar 8.

2.

anexVis: visual analytics framework for analysis of RNA expression.

Tran DT, Zhang T, Stutsman R, Might M, Desai UR, Kuberan B.

Bioinformatics. 2018 Jul 15;34(14):2510-2512. doi: 10.1093/bioinformatics/bty122.

3.

Synthetic Xylosides: Probing the Glycosaminoglycan Biosynthetic Machinery for Biomedical Applications.

Chua JS, Kuberan B.

Acc Chem Res. 2017 Nov 21;50(11):2693-2705. doi: 10.1021/acs.accounts.7b00289. Epub 2017 Oct 23. Review.

PMID:
29058876
4.

Regulation of glycosaminoglycan biogenesis is critical for sensitive-period-dependent vocal ontogeny.

Mencio CP, My Tran V, Quintero MV, Koketsu M, Goller F, Kuberan B.

Dev Neurobiol. 2017 Dec;77(12):1401-1412. doi: 10.1002/dneu.22547.

5.

Ruthenium(II)- and copper(I)-catalyzed synthesis of click-xylosides and assessment of their glycosaminoglycan priming activity.

Mencio CP, Garud DR, Doi Y, Bi Y, Vankayalapati H, Koketsu M, Kuberan B.

Bioorg Med Chem Lett. 2017 Nov 15;27(22):5027-5030. doi: 10.1016/j.bmcl.2017.10.004. Epub 2017 Oct 3.

PMID:
29033235
6.

Immobilization alters heparin cleaving properties of heparinase I.

Bhushan I, Alabbas A, Kuberan B, Gupta RB, Desai UR.

Glycobiology. 2017 Nov 1;27(11):994-998. doi: 10.1093/glycob/cwx074.

7.

A glycan-based approach to therapeutic angiogenesis.

Chua JS, Tran VM, Kalita M, Quintero MV, Antelope O, Muruganandam G, Saijoh Y, Kuberan B.

PLoS One. 2017 Aug 1;12(8):e0182301. doi: 10.1371/journal.pone.0182301. eCollection 2017.

8.

Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease.

Bi Y, Might M, Vankayalapati H, Kuberan B.

Bioorg Med Chem Lett. 2017 Jul 1;27(13):2962-2966. doi: 10.1016/j.bmcl.2017.05.010. Epub 2017 May 5.

9.

Contributions of rapid neuromuscular transmission to the fine control of acoustic parameters of birdsong.

Mencio C, Kuberan B, Goller F.

J Neurophysiol. 2017 Feb 1;117(2):637-645. doi: 10.1152/jn.00843.2015. Epub 2016 Nov 16.

10.

BODIPY-Conjugated Xyloside Primes Fluorescent Glycosaminoglycans in the Inner Ear of Opsanus tau.

Holman HA, Tran VM, Kalita M, Nguyen LN, Arungundram S, Kuberan B, Rabbitt RD.

J Assoc Res Otolaryngol. 2016 Dec;17(6):525-540. Epub 2016 Sep 12.

11.

Chemoenzymatically prepared heparan sulfate containing rare 2-O-sulfonated glucuronic acid residues.

Boothello RS, Sarkar A, Tran VM, Nguyen TK, Sankaranarayanan NV, Mehta AY, Alabbas A, Brown S, Rossi A, Joice AC, Mencio CP, Quintero MV, Kuberan B, Desai UR.

ACS Chem Biol. 2015 Jun 19;10(6):1485-94. doi: 10.1021/acschembio.5b00071. Epub 2015 Mar 17.

PMID:
25742429
12.

Synthesis and biomedical applications of xylosides.

Kalita M, Quintero MV, Raman K, Tran VM, Kuberan B.

Methods Mol Biol. 2015;1229:517-28. doi: 10.1007/978-1-4939-1714-3_40.

PMID:
25325977
13.

A rapid, nonradioactive assay for measuring heparan sulfate C-5 epimerase activity using hydrogen/deuterium exchange-mass spectrometry.

Babu P, Victor XV, Raman K, Kuberan B.

Methods Mol Biol. 2015;1229:209-19. doi: 10.1007/978-1-4939-1714-3_19.

PMID:
25325956
14.

Synthesis of selective inhibitors of heparan sulfate and chondroitin sulfate proteoglycan biosynthesis.

Mencio C, Garud DR, Kuberan B, Koketsu M.

Methods Mol Biol. 2015;1229:69-78. doi: 10.1007/978-1-4939-1714-3_8.

PMID:
25325945
15.

Preparation of isotope-enriched heparan sulfate precursors for structural biology studies.

Victor XV, Tran VM, Kuberan B, Nguyen TK.

Methods Mol Biol. 2015;1229:43-8. doi: 10.1007/978-1-4939-1714-3_6.

PMID:
25325943
16.

Synthesis of sulfur isotope-labeled sulfate donor, 3'-phosphoadenosine-5'-phosphosulfate, for studying glycosaminoglycan functions.

Mencio C, Swarup VP, Soliai M, Kuberan B.

Methods Mol Biol. 2015;1229:37-42. doi: 10.1007/978-1-4939-1714-3_5.

PMID:
25325942
17.

Chemical modification of heparin and heparosan.

Raman K, Kuberan B, Arungundram S.

Methods Mol Biol. 2015;1229:31-6. doi: 10.1007/978-1-4939-1714-3_4.

PMID:
25325941
18.

Production of size-defined heparosan, heparan sulfate, and heparin oligosaccharides by enzymatic depolymerization.

Brown S, Kuberan B.

Methods Mol Biol. 2015;1229:21-9. doi: 10.1007/978-1-4939-1714-3_3.

PMID:
25325940
19.

Enzymatic synthesis of heparan sulfate and heparin.

Joice A, Raman K, Mencio C, Quintero MV, Brown S, Nguyen TK, Kuberan B.

Methods Mol Biol. 2015;1229:11-9. doi: 10.1007/978-1-4939-1714-3_2.

PMID:
25325939
20.

Determinants of versican-V1 proteoglycan processing by the metalloproteinase ADAMTS5.

Foulcer SJ, Nelson CM, Quintero MV, Kuberan B, Larkin J, Dours-Zimmermann MT, Zimmermann DR, Apte SS.

J Biol Chem. 2014 Oct 3;289(40):27859-73. doi: 10.1074/jbc.M114.573287. Epub 2014 Aug 13.

21.

Chemogenesis of an antiangiogenic glycosaminoglycan.

Raman K, Arungundram S, Kuberan B.

ACS Med Chem Lett. 2014 Apr 4;5(6):644-6. doi: 10.1021/ml400498d. eCollection 2014 Jun 12.

22.

Synthesis of fluorophore-tagged xylosides that prime glycosaminoglycan chains.

Tran VM, Kuberan B.

Bioconjug Chem. 2014 Feb 19;25(2):262-8. doi: 10.1021/bc400396z. Epub 2014 Feb 5.

23.

A nanosensor for ultrasensitive detection of oversulfated chondroitin sulfate contaminant in heparin.

Kalita M, Balivada S, Swarup VP, Mencio C, Raman K, Desai UR, Troyer D, Kuberan B.

J Am Chem Soc. 2014 Jan 15;136(2):554-7. doi: 10.1021/ja409170z. Epub 2014 Jan 6.

PMID:
24127748
24.

A serotonin-induced N-glycan switch regulates platelet aggregation.

Mercado CP, Quintero MV, Li Y, Singh P, Byrd AK, Talabnin K, Ishihara M, Azadi P, Rusch NJ, Kuberan B, Maroteaux L, Kilic F.

Sci Rep. 2013 Sep 30;3:2795. doi: 10.1038/srep02795.

25.

Polyunsaturated fatty acyl-coenzyme As are inhibitors of cholesterol biosynthesis in zebrafish and mice.

Karanth S, Tran VM, Kuberan B, Schlegel A.

Dis Model Mech. 2013 Nov;6(6):1365-77. doi: 10.1242/dmm.013425. Epub 2013 Sep 18.

26.

Exploiting differential surface display of chondroitin sulfate variants for directing neuronal outgrowth.

Swarup VP, Hsiao TW, Zhang J, Prestwich GD, Kuberan B, Hlady V.

J Am Chem Soc. 2013 Sep 11;135(36):13488-94. doi: 10.1021/ja4056728. Epub 2013 Aug 30.

27.

Sugar glues for broken neurons.

Swarup VP, Mencio CP, Hlady V, Kuberan B.

Biomol Concepts. 2013 Jun;4(3):233-57. doi: 10.1515/bmc-2012-0042. Review.

28.

Dimerized glycosaminoglycan chains increase FGF signaling during zebrafish development.

Nguyen TK, Tran VM, Sorna V, Eriksson I, Kojima A, Koketsu M, Loganathan D, Kjellén L, Dorsky RI, Chien CB, Kuberan B.

ACS Chem Biol. 2013 May 17;8(5):939-48. doi: 10.1021/cb400132r. Epub 2013 May 7.

PMID:
23614643
29.

Astrocytes specifically remove surface-adsorbed fibrinogen and locally express chondroitin sulfate proteoglycans.

Hsiao TW, Swarup VP, Kuberan B, Tresco PA, Hlady V.

Acta Biomater. 2013 Jul;9(7):7200-8. doi: 10.1016/j.actbio.2013.02.047. Epub 2013 Mar 14.

30.

Synthesis and assessment of glycosaminoglycan priming activity of cluster-xylosides for potential use as proteoglycan mimetics.

Tran VM, Nguyen TK, Sorna V, Loganathan D, Kuberan B.

ACS Chem Biol. 2013 May 17;8(5):949-57. doi: 10.1021/cb300665u. Epub 2013 Mar 18.

PMID:
23402705
31.

Sulfation patterns determine cellular internalization of heparin-like polysaccharides.

Raman K, Mencio C, Desai UR, Kuberan B.

Mol Pharm. 2013 Apr 1;10(4):1442-9. doi: 10.1021/mp300679a. Epub 2013 Feb 27.

32.

Discovery of novel sulfonated small molecules that inhibit vascular tube formation.

Raman K, Karuturi R, Swarup VP, Desai UR, Kuberan B.

Bioorg Med Chem Lett. 2012 Jul 1;22(13):4467-70. doi: 10.1016/j.bmcl.2012.04.014. Epub 2012 Apr 16.

33.

A synthetic heparan sulfate oligosaccharide library reveals the novel enzymatic action of D-glucosaminyl 3-O-sulfotransferase-3a.

Nguyen TK, Arungundram S, Tran VM, Raman K, Al-Mafraji K, Venot A, Boons GJ, Kuberan B.

Mol Biosyst. 2012 Feb;8(2):609-14. doi: 10.1039/c1mb05221g. Epub 2011 Nov 24.

34.

Is N-sulfation just a gateway modification during heparan sulfate biosynthesis?

Raman K, Nguyen TK, Kuberan B.

FEBS Lett. 2011 Nov 4;585(21):3420-3. doi: 10.1016/j.febslet.2011.09.030. Epub 2011 Oct 2.

35.

Investigating the mechanism of the assembly of FGF1-binding heparan sulfate motifs.

Nguyen TK, Raman K, Tran VM, Kuberan B.

FEBS Lett. 2011 Sep 2;585(17):2698-702. doi: 10.1016/j.febslet.2011.07.024. Epub 2011 Jul 26.

36.

Hydrogen/deuterium exchange-LC-MS approach to characterize the action of heparan sulfate C5-epimerase.

Babu P, Victor XV, Nelsen E, Nguyen TK, Raman K, Kuberan B.

Anal Bioanal Chem. 2011 Jul;401(1):237-44. doi: 10.1007/s00216-011-5087-z. Epub 2011 May 15.

37.

Novel glycosaminoglycan biosynthetic inhibitors affect tumor-associated angiogenesis.

Raman K, Ninomiya M, Nguyen TK, Tsuzuki Y, Koketsu M, Kuberan B.

Biochem Biophys Res Commun. 2011 Jan 7;404(1):86-9. doi: 10.1016/j.bbrc.2010.11.069. Epub 2010 Nov 19.

38.

4-deoxy-4-fluoro-xyloside derivatives as inhibitors of glycosaminoglycan biosynthesis.

Tsuzuki Y, Nguyen TK, Garud DR, Kuberan B, Koketsu M.

Bioorg Med Chem Lett. 2010 Dec 15;20(24):7269-73. doi: 10.1016/j.bmcl.2010.10.085. Epub 2010 Oct 23.

PMID:
21074423
39.

Applications of isotopes in advancing structural and functional heparanomics.

Tran VM, Nguyen TK, Raman K, Kuberan B.

Anal Bioanal Chem. 2011 Jan;399(2):559-70. doi: 10.1007/s00216-010-4166-x. Epub 2010 Sep 14. Review.

40.

Characterization of uniformly and atom-specifically (13)C-labeled heparin and heparan sulfate polysaccharide precursors using (13)C NMR spectroscopy and ESI mass spectrometry.

Nguyen TK, Tran VM, Victor XV, Skalicky JJ, Kuberan B.

Carbohydr Res. 2010 Oct 13;345(15):2228-32. doi: 10.1016/j.carres.2010.08.011. Epub 2010 Aug 21.

41.

RGD-xyloside conjugates prime glycosaminoglycans.

Tran VM, Victor XV, Yockman JW, Kuberan B.

Glycoconj J. 2010 Aug;27(6):625-33. doi: 10.1007/s10719-010-9306-1. Epub 2010 Aug 18.

42.

Click-xylosides mitigate glioma cell invasion in vitro.

Raman K, Kuberan B.

Mol Biosyst. 2010 Oct;6(10):1800-2. doi: 10.1039/c0mb00020e. Epub 2010 Jul 29.

PMID:
20672151
43.

Differential effects of Heparitinase I and Heparitinase III on endothelial tube formation in vitro.

Raman K, Kuberan B.

Biochem Biophys Res Commun. 2010 Jul 23;398(2):191-3. doi: 10.1016/j.bbrc.2010.06.055. Epub 2010 Jun 17.

44.

Chemical Tumor Biology of Heparan Sulfate Proteoglycans.

Raman K, Kuberan B.

Curr Chem Biol. 2010 Jan 1;4(1):20-31.

45.

Preparation and characterization of (15)N-enriched, size-defined heparan sulfate precursor oligosaccharides.

Sigulinsky C, Babu P, Victor XV, Kuberan B.

Carbohydr Res. 2010 Jan 26;345(2):250-6. doi: 10.1016/j.carres.2009.10.024. Epub 2009 Nov 3.

46.

Fluorescent-tagged heparan sulfate precursor oligosaccharides to probe the enzymatic action of heparitinase I.

Babu P, Kuberan B.

Anal Biochem. 2010 Jan 1;396(1):124-32. doi: 10.1016/j.ab.2009.08.036. Epub 2009 Sep 2.

47.

Investigating the elusive mechanism of glycosaminoglycan biosynthesis.

Victor XV, Nguyen TK, Ethirajan M, Tran VM, Nguyen KV, Kuberan B.

J Biol Chem. 2009 Sep 18;284(38):25842-53. doi: 10.1074/jbc.M109.043208. Epub 2009 Jul 23.

48.

Inhibition of heparan sulfate and chondroitin sulfate proteoglycan biosynthesis.

Garud DR, Tran VM, Victor XV, Koketsu M, Kuberan B.

J Biol Chem. 2008 Oct 24;283(43):28881-7. doi: 10.1074/jbc.M805939200. Epub 2008 Aug 14.

49.

"Click" xylosides initiate glycosaminoglycan biosynthesis in a mammalian cell line.

Kuberan B, Ethirajan M, Victor XV, Tran V, Nguyen K, Do A.

Chembiochem. 2008 Jan 25;9(2):198-200. No abstract available.

PMID:
18085541
50.

Characterization of splenic glycosaminoglycans accumulated in vivo in experimentally induced amyloid-susceptible and amyloid-resistant mice.

Sugumaran G, Elliott-Bryant R, Phung N, Vitseva O, Kuberan B, Lech M.

Scand J Immunol. 2004 Dec;60(6):574-83.

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