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Items: 1 to 50 of 184

1.

Water-soluble allyl sulfones for dual site-specific labelling of proteins and cyclic peptides.

Wang T, Riegger A, Lamla M, Wiese S, Oeckl P, Otto M, Wu Y, Fischer S, Barth H, Kuan SL, Weil T.

Chem Sci. 2016 May 1;7(5):3234-3239. doi: 10.1039/c6sc00005c. Epub 2016 Jan 29.

2.

"Tag and Modify" Protein Conjugation with Dynamic Covalent Chemistry.

Zegota M, Wang T, Seidler C, Ng DYW, Kuan SL, Weil T.

Bioconjug Chem. 2018 Jun 27. doi: 10.1021/acs.bioconjchem.8b00358. [Epub ahead of print]

PMID:
29949347
3.

Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions.

Morsbach S, Gonella G, Mailänder V, Wegner S, Wu S, Weidner T, Berger R, Koynov K, Vollmer D, Encinas N, Kuan SL, Bereau T, Kremer K, Weil T, Bonn M, Butt HJ, Landfester K.

Angew Chem Int Ed Engl. 2018 Apr 17. doi: 10.1002/anie.201712448. [Epub ahead of print]

PMID:
29663610
4.

The vagal ganglia transcriptome identifies candidate therapeutics for airway hyperreactivity.

Reznikov LR, Meyerholz DK, Abou Alaiwa MH, Kuan SP, Liao YJ, Bormann NL, Bair TB, Price M, Stoltz DA, Welsh MJ.

Am J Physiol Lung Cell Mol Physiol. 2018 Apr 5. doi: 10.1152/ajplung.00557.2017. [Epub ahead of print]

5.

Author Correction: Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation.

Preissl S, Fang R, Huang H, Zhao Y, Raviram R, Gorkin DU, Zhang Y, Sos BC, Afzal V, Dickel DE, Kuan S, Visel A, Pennacchio LA, Zhang K, Ren B.

Nat Neurosci. 2018 Jul;21(7):1015. doi: 10.1038/s41593-018-0114-4.

PMID:
29497140
6.

Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation.

Preissl S, Fang R, Huang H, Zhao Y, Raviram R, Gorkin DU, Zhang Y, Sos BC, Afzal V, Dickel DE, Kuan S, Visel A, Pennacchio LA, Zhang K, Ren B.

Nat Neurosci. 2018 Mar;21(3):432-439. doi: 10.1038/s41593-018-0079-3. Epub 2018 Feb 12. Erratum in: Nat Neurosci. 2018 Mar 1;:.

PMID:
29434377
7.

Solitary Cholinergic Stimulation Induces Airway Hyperreactivity and Transcription of Distinct Pro-inflammatory Pathways.

Reznikov LR, Meyerholz DK, Kuan SP, Guevara MV, Atanasova KR, Abou Alaiwa MH.

Lung. 2018 Apr;196(2):219-229. doi: 10.1007/s00408-018-0091-0. Epub 2018 Jan 29.

PMID:
29380034
8.

Chemoselective Dual Labeling of Native and Recombinant Proteins.

Agrawalla BK, Wang T, Riegger A, Domogalla MP, Steinbrink K, Dörfler T, Chen X, Boldt F, Lamla M, Michaelis J, Kuan SL, Weil T.

Bioconjug Chem. 2018 Jan 17;29(1):29-34. doi: 10.1021/acs.bioconjchem.7b00675. Epub 2017 Dec 20.

PMID:
29231709
9.

Wnt/β-Catenin Pathway Activation Mediates Adaptive Resistance to BRAF Inhibition in Colorectal Cancer.

Chen G, Gao C, Gao X, Zhang DH, Kuan SF, Burns TF, Hu J.

Mol Cancer Ther. 2018 Apr;17(4):806-813. doi: 10.1158/1535-7163.MCT-17-0561. Epub 2017 Nov 22.

PMID:
29167314
10.

Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein-DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity.

Gačanin J, Kovtun A, Fischer S, Schwager V, Quambusch J, Kuan SL, Liu W, Boldt F, Li C, Yang Z, Liu D, Wu Y, Weil T, Barth H, Ignatius A.

Adv Healthc Mater. 2017 Nov;6(21). doi: 10.1002/adhm.201700392. Epub 2017 Jul 31.

PMID:
28758712
11.

MAP4K4 is a novel MAPK/ERK pathway regulator required for lung adenocarcinoma maintenance.

Gao X, Chen G, Gao C, Zhang DH, Kuan SF, Stabile LP, Liu G, Hu J.

Mol Oncol. 2017 Jun;11(6):628-639. doi: 10.1002/1878-0261.12055. Epub 2017 May 2.

12.

Neoadjuvant therapy in microsatellite-stable colorectal carcinoma induces concomitant loss of MSH6 and Ki-67 expression.

Kuan SF, Ren B, Brand R, Dudley B, Pai RK.

Hum Pathol. 2017 May;63:33-39. doi: 10.1016/j.humpath.2017.02.003. Epub 2017 Feb 21.

PMID:
28232158
13.

THADA fusion is a mechanism of IGF2BP3 activation and IGF1R signaling in thyroid cancer.

Panebianco F, Kelly LM, Liu P, Zhong S, Dacic S, Wang X, Singhi AD, Dhir R, Chiosea SI, Kuan SF, Bhargava R, Dabbs D, Trivedi S, Gandhi M, Diaz R, Wald AI, Carty SE, Ferris RL, Lee AV, Nikiforova MN, Nikiforov YE.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2307-2312. doi: 10.1073/pnas.1614265114. Epub 2017 Feb 13.

14.

Views of faculty members in a medical school with regards to error disclosure and reporting to parents and/or higher authorities.

Wong CH, Phuah AC, Naik NS, Choo WS, Ting HS, Kuan SM, Teng CL, Sivalingam N.

Med J Malaysia. 2016 Oct;71(5):244-249.

15.

Opposing roles of KIT and ABL1 in the therapeutic response of gastrointestinal stromal tumor (GIST) cells to imatinib mesylate.

Rausch JL, Boichuk S, Ali AA, Patil SS, Liu L, Lee DM, Brown MF, Makielski KR, Liu Y, Taguchi T, Kuan SF, Duensing A.

Oncotarget. 2017 Jan 17;8(3):4471-4483. doi: 10.18632/oncotarget.13882.

16.

Site-Selective Disulfide Modification of Proteins: Expanding Diversity beyond the Proteome.

Kuan SL, Wang T, Weil T.

Chemistry. 2016 Nov 21;22(48):17112-17129. doi: 10.1002/chem.201602298. Epub 2016 Oct 25. Review.

17.
18.

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A.

Nature. 2016 Sep 22;537(7621):548-552. doi: 10.1038/nature19360. Epub 2016 Sep 14.

PMID:
27626377
19.

MLH1-deficient Colorectal Carcinoma With Wild-type BRAF and MLH1 Promoter Hypermethylation Harbor KRAS Mutations and Arise From Conventional Adenomas.

Farchoukh L, Kuan SF, Dudley B, Brand R, Nikiforova M, Pai RK.

Am J Surg Pathol. 2016 Oct;40(10):1390-9. doi: 10.1097/PAS.0000000000000695.

PMID:
27438990
20.

Effect of BBX-B8 overexpression on development, body weight, silk protein synthesis and egg diapause of Bombyx mori.

Zheng X, Gong Y, Kumar D, Chen F, Kuan S, Liang Z, Hu X, Cao G, Xue R, Gong C.

Transgenic Res. 2016 Aug;25(4):507-16. doi: 10.1007/s11248-016-9947-3. Epub 2016 Mar 7.

PMID:
26951193
21.

A Supramolecular Approach toward Bioinspired PAMAM-Dendronized Fusion Toxins.

Kuan SL, Förtsch C, Ng DY, Fischer S, Tokura Y, Liu W, Wu Y, Koynov K, Barth H, Weil T.

Macromol Biosci. 2016 Jun;16(6):803-10. doi: 10.1002/mabi.201500417. Epub 2016 Feb 2.

PMID:
26833574
22.

Colorectal poorly differentiated neuroendocrine carcinomas frequently exhibit BRAF mutations and are associated with poor overall survival.

Olevian DC, Nikiforova MN, Chiosea S, Sun W, Bahary N, Kuan SF, Pai RK.

Hum Pathol. 2016 Mar;49:124-34. doi: 10.1016/j.humpath.2015.11.004. Epub 2015 Nov 17.

PMID:
26826419
23.

EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling.

Liu F, Hon GC, Villa GR, Turner KM, Ikegami S, Yang H, Ye Z, Li B, Kuan S, Lee AY, Zanca C, Wei B, Lucey G, Jenkins D, Zhang W, Barr CL, Furnari FB, Cloughesy TF, Yong WH, Gahman TC, Shiau AK, Cavenee WK, Ren B, Mischel PS.

Mol Cell. 2015 Oct 15;60(2):307-18. doi: 10.1016/j.molcel.2015.09.002. Epub 2015 Oct 8.

24.

FAK/PYK2 promotes the Wnt/β-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3β.

Gao C, Chen G, Kuan SF, Zhang DH, Schlaepfer DD, Hu J.

Elife. 2015 Sep 3;4. doi: 10.7554/eLife.10072.

25.

Protein-polymer therapeutics: a macromolecular perspective.

Wu Y, Ng DY, Kuan SL, Weil T.

Biomater Sci. 2015 Feb;3(2):214-30. doi: 10.1039/c4bm00270a. Epub 2014 Oct 13.

PMID:
26218113
26.

Improvement of bio-corrosion resistance for Ti42Zr40Si15Ta3 metallic glasses in simulated body fluid by annealing within supercooled liquid region.

Huang CH, Lai JJ, Wei TY, Chen YH, Wang X, Kuan SY, Huang JC.

Mater Sci Eng C Mater Biol Appl. 2015;52:144-50. doi: 10.1016/j.msec.2015.03.056. Epub 2015 Mar 26.

PMID:
25953551
27.

Integrative analysis of haplotype-resolved epigenomes across human tissues.

Leung D, Jung I, Rajagopal N, Schmitt A, Selvaraj S, Lee AY, Yen CA, Lin S, Lin Y, Qiu Y, Xie W, Yue F, Hariharan M, Ray P, Kuan S, Edsall L, Yang H, Chi NC, Zhang MQ, Ecker JR, Ren B.

Nature. 2015 Feb 19;518(7539):350-354. doi: 10.1038/nature14217.

28.

A comparative encyclopedia of DNA elements in the mouse genome.

Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, Sandstrom R, Ma Z, Davis C, Pope BD, Shen Y, Pervouchine DD, Djebali S, Thurman RE, Kaul R, Rynes E, Kirilusha A, Marinov GK, Williams BA, Trout D, Amrhein H, Fisher-Aylor K, Antoshechkin I, DeSalvo G, See LH, Fastuca M, Drenkow J, Zaleski C, Dobin A, Prieto P, Lagarde J, Bussotti G, Tanzer A, Denas O, Li K, Bender MA, Zhang M, Byron R, Groudine MT, McCleary D, Pham L, Ye Z, Kuan S, Edsall L, Wu YC, Rasmussen MD, Bansal MS, Kellis M, Keller CA, Morrissey CS, Mishra T, Jain D, Dogan N, Harris RS, Cayting P, Kawli T, Boyle AP, Euskirchen G, Kundaje A, Lin S, Lin Y, Jansen C, Malladi VS, Cline MS, Erickson DT, Kirkup VM, Learned K, Sloan CA, Rosenbloom KR, Lacerda de Sousa B, Beal K, Pignatelli M, Flicek P, Lian J, Kahveci T, Lee D, Kent WJ, Ramalho Santos M, Herrero J, Notredame C, Johnson A, Vong S, Lee K, Bates D, Neri F, Diegel M, Canfield T, Sabo PJ, Wilken MS, Reh TA, Giste E, Shafer A, Kutyavin T, Haugen E, Dunn D, Reynolds AP, Neph S, Humbert R, Hansen RS, De Bruijn M, Selleri L, Rudensky A, Josefowicz S, Samstein R, Eichler EE, Orkin SH, Levasseur D, Papayannopoulou T, Chang KH, Skoultchi A, Gosh S, Disteche C, Treuting P, Wang Y, Weiss MJ, Blobel GA, Cao X, Zhong S, Wang T, Good PJ, Lowdon RF, Adams LB, Zhou XQ, Pazin MJ, Feingold EA, Wold B, Taylor J, Mortazavi A, Weissman SM, Stamatoyannopoulos JA, Snyder MP, Guigo R, Gingeras TR, Gilbert DM, Hardison RC, Beer MA, Ren B; Mouse ENCODE Consortium.

Nature. 2014 Nov 20;515(7527):355-64. doi: 10.1038/nature13992.

29.

A disulfide intercalator toolbox for the site-directed modification of polypeptides.

Wang T, Wu Y, Kuan SL, Dumele O, Lamla M, Ng DY, Arzt M, Thomas J, Mueller JO, Barner-Kowollik C, Weil T.

Chemistry. 2015 Jan 2;21(1):228-38. doi: 10.1002/chem.201403965. Epub 2014 Oct 30.

PMID:
25359430
30.

Programming supramolecular biohybrids as precision therapeutics.

Ng DY, Wu Y, Kuan SL, Weil T.

Acc Chem Res. 2014 Dec 16;47(12):3471-80. doi: 10.1021/ar5002445. Epub 2014 Oct 30.

PMID:
25357135
31.

Programmable protein-DNA hybrid hydrogels for the immobilization and release of functional proteins.

Wu Y, Li C, Boldt F, Wang Y, Kuan SL, Tran TT, Mikhalevich V, Förtsch C, Barth H, Yang Z, Liu D, Weil T.

Chem Commun (Camb). 2014 Dec 4;50(93):14620-2. doi: 10.1039/c4cc07144a.

PMID:
25311614
32.

5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation.

Hon GC, Song CX, Du T, Jin F, Selvaraj S, Lee AY, Yen CA, Ye Z, Mao SQ, Wang BA, Kuan S, Edsall LE, Zhao BS, Xu GL, He C, Ren B.

Mol Cell. 2014 Oct 23;56(2):286-297. doi: 10.1016/j.molcel.2014.08.026. Epub 2014 Sep 25.

33.

Crystal structure of a conserved hypothetical protein MJ0927 from Methanocaldococcus jannaschii reveals a novel quaternary assembly in the Nif3 family.

Chen SC, Huang CH, Yang CS, Kuan SM, Lin CT, Chou SH, Chen Y.

Biomed Res Int. 2014;2014:171263. doi: 10.1155/2014/171263. Epub 2014 Aug 28.

34.

Human polyomavirus 7-associated pruritic rash and viremia in transplant recipients.

Ho J, Jedrych JJ, Feng H, Natalie AA, Grandinetti L, Mirvish E, Crespo MM, Yadav D, Fasanella KE, Proksell S, Kuan SF, Pastrana DV, Buck CB, Shuda Y, Moore PS, Chang Y.

J Infect Dis. 2015 May 15;211(10):1560-5. doi: 10.1093/infdis/jiu524. Epub 2014 Sep 17.

35.

A polyphenylene dendrimer drug transporter with precisely positioned amphiphilic surface patches.

Stangenberg R, Wu Y, Hedrich J, Kurzbach D, Wehner D, Weidinger G, Kuan SL, Jansen MI, Jelezko F, Luhmann HJ, Hinderberger D, Weil T, Müllen K.

Adv Healthc Mater. 2015 Feb 18;4(3):377-84. doi: 10.1002/adhm.201400291. Epub 2014 Sep 2.

PMID:
25182694
36.

BRAF-mutated microsatellite stable colorectal carcinoma: an aggressive adenocarcinoma with reduced CDX2 and increased cytokeratin 7 immunohistochemical expression.

Landau MS, Kuan SF, Chiosea S, Pai RK.

Hum Pathol. 2014 Aug;45(8):1704-12. doi: 10.1016/j.humpath.2014.04.008. Epub 2014 Apr 24.

PMID:
24908142
37.

Hematochezia Associated with Sevalamer-Induced Mucosal Injury.

Chintamaneni P, Das R, Kuan SF, Kermanshahi TR, Hashash JG.

ACG Case Rep J. 2014 Apr 4;1(3):145-7. doi: 10.14309/crj.2014.32. eCollection 2014 Apr.

38.

Immunohistochemical detection of BRAF V600E mutant protein using the VE1 antibody in colorectal carcinoma is highly concordant with molecular testing but requires rigorous antibody optimization.

Kuan SF, Navina S, Cressman KL, Pai RK.

Hum Pathol. 2014 Mar;45(3):464-72. doi: 10.1016/j.humpath.2013.10.026. Epub 2013 Nov 4.

PMID:
24529329
39.

Crystal structures of the archaeal UDP-GlcNAc 2-epimerase from Methanocaldococcus jannaschii reveal a conformational change induced by UDP-GlcNAc.

Chen SC, Huang CH, Yang CS, Liu JS, Kuan SM, Chen Y.

Proteins. 2014 Jul;82(7):1519-26. doi: 10.1002/prot.24516. Epub 2014 Feb 18.

PMID:
24470206
40.

Serrated lesions of the appendix frequently harbor KRAS mutations and not BRAF mutations indicating a distinctly different serrated neoplastic pathway in the appendix.

Pai RK, Hartman DJ, Gonzalo DH, Lai KK, Downs-Kelly E, Goldblum JR, Liu X, Patil DT, Bennett AE, Plesec TP, Kuan SF, Nikiforova MN, Shadrach B, Pai RK.

Hum Pathol. 2014 Feb;45(2):227-35. doi: 10.1016/j.humpath.2013.10.021. Epub 2013 Oct 30.

PMID:
24439221
41.

Unbiased compound screening identifies unexpected drug sensitivities and novel treatment options for gastrointestinal stromal tumors.

Boichuk S, Lee DJ, Mehalek KR, Makielski KR, Wozniak A, Seneviratne DS, Korzeniewski N, Cuevas R, Parry JA, Brown MF, Zewe J, Taguchi T, Kuan SF, Schöffski P, Debiec-Rychter M, Duensing A.

Cancer Res. 2014 Feb 15;74(4):1200-13. doi: 10.1158/0008-5472.CAN-13-1955. Epub 2014 Jan 2.

42.

Constructing hybrid protein zymogens through protective dendritic assembly.

Ng DY, Arzt M, Wu Y, Kuan SL, Lamla M, Weil T.

Angew Chem Int Ed Engl. 2014 Jan 3;53(1):324-8. doi: 10.1002/anie.201308533. Epub 2013 Dec 20.

PMID:
24375743
43.

MUC2 expression is an adverse prognostic factor in superficial gastroesophageal adenocarcinomas.

Davison JM, Ellis ST, Foxwell TJ, Luketich JD, Gibson MK, Kuan SF, Nason KS.

Hum Pathol. 2014 Mar;45(3):540-8. doi: 10.1016/j.humpath.2013.10.020. Epub 2013 Oct 30.

44.

Tuning polarity of polyphenylene dendrimers by patched surface amphiphilicity--precise control over size, shape, and polarity.

Stangenberg R, Saeed I, Kuan SL, Baumgarten M, Weil T, Klapper M, Müllen K.

Macromol Rapid Commun. 2014 Jan;35(2):152-160. doi: 10.1002/marc.201300671. Epub 2013 Nov 24.

PMID:
24272967
45.

Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development.

Nakamoto C, Kuan SL, Findlay AS, Durward E, Ouyang Z, Zakrzewska ED, Endo T, Nakamoto M.

Mol Biol Cell. 2014 Jan;25(2):234-44. doi: 10.1091/mbc.E13-08-0453. Epub 2013 Nov 20.

46.

pH responsive Janus-like supramolecular fusion proteins for functional protein delivery.

Kuan SL, Ng DY, Wu Y, Förtsch C, Barth H, Doroshenko M, Koynov K, Meier C, Weil T.

J Am Chem Soc. 2013 Nov 20;135(46):17254-7. doi: 10.1021/ja4084122. Epub 2013 Nov 7.

PMID:
24156787
47.

Iron Pill-Induced Gastritis.

Hashash JG, Proksell S, Kuan SF, Behari J.

ACG Case Rep J. 2013 Oct 8;1(1):13-5. doi: 10.14309/crj.2013.7. eCollection 2013 Oct.

48.
49.

Endoscopic, ultrasonographic, and pathologic correlation of lymphocytic gastritis.

Aggarwal N, Kuan SF, Fasanella KE.

Endoscopy. 2013;45 Suppl 2 UCTN:E145-6. doi: 10.1055/s-0032-1326447. Epub 2013 May 28. No abstract available.

PMID:
23716104
50.

Epigenomic analysis of multilineage differentiation of human embryonic stem cells.

Xie W, Schultz MD, Lister R, Hou Z, Rajagopal N, Ray P, Whitaker JW, Tian S, Hawkins RD, Leung D, Yang H, Wang T, Lee AY, Swanson SA, Zhang J, Zhu Y, Kim A, Nery JR, Urich MA, Kuan S, Yen CA, Klugman S, Yu P, Suknuntha K, Propson NE, Chen H, Edsall LE, Wagner U, Li Y, Ye Z, Kulkarni A, Xuan Z, Chung WY, Chi NC, Antosiewicz-Bourget JE, Slukvin I, Stewart R, Zhang MQ, Wang W, Thomson JA, Ecker JR, Ren B.

Cell. 2013 May 23;153(5):1134-48. doi: 10.1016/j.cell.2013.04.022. Epub 2013 May 9.

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