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Liver disease-associated keratin 8 and 18 mutations modulate keratin acetylation and methylation.

Jang KH, Yoon HN, Lee J, Yi H, Park SY, Lee SY, Lim Y, Lee HJ, Cho JW, Paik YK, Hancock WS, Ku NO.

FASEB J. 2019 Jun 14:fj201800263RR. doi: 10.1096/fj.201800263RR. [Epub ahead of print]


A High Visceral-To-Subcutaneous Fat Ratio is an Independent Predictor of Surgical Site Infection after Gastrectomy.

Kim JH, Kim J, Lee WJ, Seong H, Choi H, Ahn JY, Jeong SJ, Ku NS, Son T, Kim HI, Han SH, Choi JY, Yeom JS, Hyung WJ, Song YG, Noh SH.

J Clin Med. 2019 Apr 11;8(4). pii: E494. doi: 10.3390/jcm8040494.


Changes in the utilization patterns of antifungal agents, medical cost and clinical outcomes of candidemia from the health-care benefit expansion to include newer antifungal agents.

Choi H, Kim JH, Seong H, Lee W, Jeong W, Ahn JY, Jeong SJ, Ku NS, Yeom JS, Kim YK, Kim HY, Song YG, Kim JM, Choi JY.

Int J Infect Dis. 2019 Jun;83:49-55. doi: 10.1016/j.ijid.2019.03.039. Epub 2019 Apr 5.


Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from MERS in South Korea.

Choi JY, Oh JO, Ahn JY, Choi H, Kim JH, Seong H, Jeong SJ, Ku NS, Yeom JS, Choi JP.

Clin Exp Vaccine Res. 2019 Jan;8(1):86-88. doi: 10.7774/cevr.2019.8.1.86. Epub 2019 Jan 31.


Pregnancy Rates and Outcomes of HIV-Infected Women in Korea.

Choi H, Kim MH, Lee SJ, Kim EJ, Lee W, Jeong W, Jung IY, Ahn JY, Jeong SJ, Ku NS, Baek JH, Choi YH, Kim HY, Kim JM, Choi JY.

J Korean Med Sci. 2018 Oct 25;33(47):e296. doi: 10.3346/jkms.2018.33.e296. eCollection 2018 Nov 19.


Integrase Strand Transfer Inhibitor Resistance Mutations in Antiretroviral Therapy-Naive and Treatment-Experienced HIV Patients in South Korea.

Jeong W, Jung IY, Choi H, Kim JH, Seong H, Ahn JY, Jeong SJ, Ku NS, Kim JM, Choi JY.

AIDS Res Hum Retroviruses. 2019 Feb;35(2):213-216. doi: 10.1089/AID.2018.0213. Epub 2018 Oct 23.


Korea HIV/AIDS Cohort Study: study design and baseline characteristics.

Choi BY, Choi JY, Han SH, Kim SI, Kee MK, Kim MJ, Kim SW, Kim SS, Kim YM, Ku NS, Lee JS, Lee JS, Choi Y, Park KS, Song JY, Woo JH, Kang MW, Kim J.

Epidemiol Health. 2018 Jun 6;40:e2018023. doi: 10.4178/epih.e2018023. eCollection 2018.


Core-binding factor acute myeloid leukemia with t(8;21): Risk factors and a novel scoring system (I-CBFit).

Ustun C, Morgan E, Moodie EEM, Pullarkat S, Yeung C, Broesby-Olsen S, Ohgami R, Kim Y, Sperr W, Vestergaard H, Chen D, Kluin PM, Dolan M, Mrózek K, Czuchlewski D, Horny HP, George TI, Kristensen TK, Ku NK, Yi CA, Møller MB, Marcucci G, Baughn L, Schiefer AI, Hilberink JR, Pullarkat V, Shanley R, Kohlschmidt J, Coulombe J, Salhotra A, Soma L, Cho C, Linden MA, Akin C, Gotlib J, Hoermann G, Hornick J, Nakamura R, Deeg J, Bloomfield CD, Weisdorf D, Litzow MR, Valent P, Huls G, Perales MA, Borthakur G.

Cancer Med. 2018 Sep;7(9):4447-4455. doi: 10.1002/cam4.1733. Epub 2018 Aug 16.


Effects of Early Exercise Rehabilitation on Functional Recovery in Patients with Severe Sepsis.

Ahn JY, Song JE, Ann HW, Jeon Y, Ahn MY, Jung IY, Kim MH, Jeong W, Jeong SJ, Ku NS, Kim JM, Na S, Cho SR, Choi JY.

Yonsei Med J. 2018 Sep;59(7):843-851. doi: 10.3349/ymj.2018.59.7.843.


Chronic kidney disease with genitourinary tuberculosis: old disease but ongoing complication.

Kim EJ, Lee W, Jeong WY, Choi H, Jung IY, Ahn JY, Jeong SJ, Ku NS, Choi JY, Choi YH, Song YG, Kim JM.

BMC Nephrol. 2018 Aug 2;19(1):193. doi: 10.1186/s12882-018-0994-2.


The role of keratins in the digestive system: lessons from transgenic mouse models.

Yi H, Yoon HN, Kim S, Ku NO.

Histochem Cell Biol. 2018 Oct;150(4):351-359. doi: 10.1007/s00418-018-1695-4. Epub 2018 Jul 24. Review.


A Simple Scoring System Using the Red Blood Cell Distribution Width, Delta Neutrophil Index, and Platelet Count to Predict Mortality in Patients With Severe Sepsis and Septic Shock.

Kim YC, Song JE, Kim EJ, Choi H, Jeong WY, Jung IY, Jeong SJ, Ku NS, Choi JY, Song YG, Kim JM.

J Intensive Care Med. 2018 Jan 1:885066618787448. doi: 10.1177/0885066618787448. [Epub ahead of print]


Prevalence of C-C chemokine receptor type 5 tropism among human immunodeficiency virus 1-infected patients in South Korea.

Song JE, Ahn MY, Kim WJ, Kim SW, Lee JS, Ku NS, Kim JH, Kim KH, Ann H, Choi JY.

J Med Virol. 2018 Nov;90(11):1720-1723. doi: 10.1002/jmv.25254. Epub 2018 Jul 24.


An Imported Case of Brucella melitensis Infection in South Korea.

Lee JY, Jeon Y, Ahn MY, Ann HW, Jung IY, Jung W, Kim MH, Ahn JY, Song JE, Kim YC, Oh DH, Kim EJ, Jeong SJ, Ku NS, Kim H, Lee K, Kim JM, Choi JY.

Infect Chemother. 2018 Jun;50(2):149-152. doi: 10.3947/ic.2018.50.2.149.


Risk factors for mortality in patients with Pseudomonas aeruginosa pneumonia: Clinical impact of mucA gene mutation.

Jung IY, Jeong SJ, Lee KM, Ahn JY, Ku NS, Han SH, Choi JY, Yong D, Yoon SS, Song YG, Jeong SH, Kim JM, Lee K.

Respir Med. 2018 Jul;140:27-31. doi: 10.1016/j.rmed.2018.05.017. Epub 2018 May 21.


Oncogenic TRK fusions are amenable to inhibition in hematologic malignancies.

Taylor J, Pavlick D, Yoshimi A, Marcelus C, Chung SS, Hechtman JF, Benayed R, Cocco E, Durham BH, Bitner L, Inoue D, Chung YR, Mullaney K, Watts JM, Diamond EL, Albacker LA, Mughal TI, Ebata K, Tuch BB, Ku N, Scaltriti M, Roshal M, Arcila M, Ali S, Hyman DM, Park JH, Abdel-Wahab O.

J Clin Invest. 2018 Aug 31;128(9):3819-3825. doi: 10.1172/JCI120787. Epub 2018 Aug 6.


Long-Term Moderate Exercise Rescues Age-Related Decline in Hippocampal Neuronal Complexity and Memory.

Tsai SF, Ku NW, Wang TF, Yang YH, Shih YH, Wu SY, Lee CW, Yu M, Yang TT, Kuo YM.

Gerontology. 2018;64(6):551-561. doi: 10.1159/000488589. Epub 2018 May 7.


The sweet side of vimentin.

Snider NT, Ku NO, Omary MB.

Elife. 2018 Mar 7;7. pii: e35336. doi: 10.7554/eLife.35336.


Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.

Drilon A, Laetsch TW, Kummar S, DuBois SG, Lassen UN, Demetri GD, Nathenson M, Doebele RC, Farago AF, Pappo AS, Turpin B, Dowlati A, Brose MS, Mascarenhas L, Federman N, Berlin J, El-Deiry WS, Baik C, Deeken J, Boni V, Nagasubramanian R, Taylor M, Rudzinski ER, Meric-Bernstam F, Sohal DPS, Ma PC, Raez LE, Hechtman JF, Benayed R, Ladanyi M, Tuch BB, Ebata K, Cruickshank S, Ku NC, Cox MC, Hawkins DS, Hong DS, Hyman DM.

N Engl J Med. 2018 Feb 22;378(8):731-739. doi: 10.1056/NEJMoa1714448.


Antibiotic-Related Adverse Drug Reactions at a Tertiary Care Hospital in South Korea.

Jung IY, Kim JJ, Lee SJ, Kim J, Seong H, Jeong W, Choi H, Jeong SJ, Ku NS, Han SH, Choi JY, Song YG, Park JW, Kim JM.

Biomed Res Int. 2017;2017:4304973. doi: 10.1155/2017/4304973. Epub 2017 Dec 31.


Use of CD42b immunohistochemical stain for the detection of Histoplasma.

Ku NK, Pullarkat ST, Kim YS, Cheng L, O'Malley D.

Ann Diagn Pathol. 2018 Feb;32:47-50. doi: 10.1016/j.anndiagpath.2017.10.002. Epub 2017 Oct 25.


Comparison of the efficacy of nafcillin and glycopeptides as definitive therapy for patients with methicillin-susceptible Staphylococcus aureus bacteremia: a retrospective cohort study.

Oh DH, Kim JJ, Kim J, Seong H, Lee SJ, Kim YC, Kim EJ, Jung IY, Jeong WY, Jeong SJ, Ku NS, Han SH, Choi JY, Song YG, Kim JM.

BMC Infect Dis. 2018 Jan 30;18(1):60. doi: 10.1186/s12879-018-2978-z.


A Case of Community-Acquired Pneumonia Caused by Multidrug-Resistant Acinetobacter baumannii in Korea.

Son YW, Jung IY, Ahn MY, Jeon YD, Ann HW, Ahn JY, Ku NS, Han SH, Choi JY, Song YG, Kim JM.

Infect Chemother. 2017 Dec;49(4):297-300. doi: 10.3947/ic.2017.49.4.297.


Genomic Heterogeneity Underlies Mixed Response to Tropomyosin Receptor Kinase Inhibition in Recurrent Glioma.

Schram AM, Jonsson P, Drilon A, Bale TA, Hechtman JF, Benayed R, Hanusch B, Young RJ, Grommes C, Ku N, Kaley T, Hyman DM, Taylor BS.

JCO Precis Oncol. 2018;2. doi: 10.1200/PO.18.00089. Epub 2018 Aug 8. No abstract available.


Rapid Response to Larotrectinib (LOXO-101) in an Adult Chemotherapy-Naive Patients With Advanced Triple-Negative Secretory Breast Cancer Expressing ETV6-NTRK3 Fusion.

Landman Y, Ilouze M, Wein S, Neiman V, Yerushalmi R, Yakimov M, Ku N, Schrock AB, Ali S, Peled N.

Clin Breast Cancer. 2018 Jun;18(3):e267-e270. doi: 10.1016/j.clbc.2017.11.017. Epub 2017 Nov 28. No abstract available.


Unusual finding of a megakaryocyte in a peripheral blood smear.

Ku NK, Rashidi H.

Blood. 2017 Dec 7;130(23):2573. doi: 10.1182/blood-2017-08-803635. No abstract available.


An increased chloride level in hypochloremia is associated with decreased mortality in patients with severe sepsis or septic shock.

Oh HJ, Kim SJ, Kim YC, Kim EJ, Jung IY, Oh DH, Jeong SJ, Ku NS, Han SH, Choi JY, Song YG, Ryu DR, Kim JM.

Sci Rep. 2017 Nov 21;7(1):15883. doi: 10.1038/s41598-017-16238-z.


An extremely rare case of concurrent BRAF V600E mutation driven hairy cell leukemia and melanoma: case report and review of literature.

Ghorbani-Aghbolaghi A, Lechpammer M, Ali SF, Ku NK, Dwyre DM, Rashidi HH.

Autops Case Rep. 2017 Sep 30;7(3):13-19. doi: 10.4322/acr.2017.032. eCollection 2017 Jul-Sep.


Risk factors for mortality in patients with low lactate level and septic shock.

Oh DH, Kim MH, Jeong WY, Kim YC, Kim EJ, Song JE, Jung IY, Jeong SJ, Ku NS, Choi JY, Song YG, Kim JM.

J Microbiol Immunol Infect. 2019 Jun;52(3):418-425. doi: 10.1016/j.jmii.2017.08.009. Epub 2017 Aug 26.


Optimal geometrical design of inertial vibration DC piezoelectric nanogenerators based on obliquely aligned InN nanowire arrays.

Ku NJ, Liu G, Wang CH, Gupta K, Liao WS, Ban D, Liu CP.

Nanoscale. 2017 Sep 28;9(37):14039-14046. doi: 10.1039/c7nr04689h.


Stem cell therapies for myocardial infarction in clinical trials: bioengineering and biomaterial aspects.

Higuchi A, Ku NJ, Tseng YC, Pan CH, Li HF, Kumar SS, Ling QD, Chang Y, Alarfaj AA, Munusamy MA, Benelli G, Murugan K.

Lab Invest. 2017 Oct;97(10):1167-1179. doi: 10.1038/labinvest.2017.100. Epub 2017 Sep 4. Review.


A mutation in keratin 18 that causes caspase-digestion resistance protects homozygous transgenic mice from hepatic apoptosis and injury.

Yoon HN, Yoon SY, Hong JH, Ku NO.

J Cell Sci. 2017 Aug 1;130(15):2541-2550. doi: 10.1242/jcs.187492. Epub 2017 Jun 12.


A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors.

Drilon A, Nagasubramanian R, Blake JF, Ku N, Tuch BB, Ebata K, Smith S, Lauriault V, Kolakowski GR, Brandhuber BJ, Larsen PD, Bouhana KS, Winski SL, Hamor R, Wu WI, Parker A, Morales TH, Sullivan FX, DeWolf WE, Wollenberg LA, Gordon PR, Douglas-Lindsay DN, Scaltriti M, Benayed R, Raj S, Hanusch B, Schram AM, Jonsson P, Berger MF, Hechtman JF, Taylor BS, Andrews S, Rothenberg SM, Hyman DM.

Cancer Discov. 2017 Sep;7(9):963-972. doi: 10.1158/2159-8290.CD-17-0507. Epub 2017 Jun 3.


Change in Renal Function among HIV-Infected Koreans Receiving Tenofovir Disoproxil Fumarate-Backbone Antiretroviral Therapy: A 3-Year Follow-Up Study.

Lee KH, Lee JU, Ku NS, Jeong SJ, Han SH, Choi JY, Song YG, Kim JM.

Yonsei Med J. 2017 Jul;58(4):770-777. doi: 10.3349/ymj.2017.58.4.770.


The impact of production of extended-spectrum β-lactamases on the 28-day mortality rate of patients with Proteus mirabilis bacteremia in Korea.

Ahn JY, Ann HW, Jeon Y, Ahn MY, Oh DH, Kim YC, Kim EJ, Song JE, Jung IY, Kim MH, Jeong W, Ku NS, Jeong SJ, Choi JY, Yong D, Song YG, Kim JM.

BMC Infect Dis. 2017 May 3;17(1):327. doi: 10.1186/s12879-017-2431-8.


Short Communication: HIV-1 Transmission Networks Across South Korea.

Ahn MY, Wertheim JO, Kim WJ, Kim SW, Lee JS, Ann HW, Jeon Y, Ahn JY, Song JE, Oh DH, Kim YC, Kim EJ, Jung IY, Kim MH, Jeong W, Jeong SJ, Ku NS, Kim JM, Smith DM, Choi JY.

AIDS Res Hum Retroviruses. 2017 Aug;33(8):827-831. doi: 10.1089/aid.2016.0212. Epub 2017 Mar 27.


The incidence and clinical characteristics by gender differences in patients with Kikuchi-Fujimoto disease.

Jung IY, Ann HW, Kim JJ, Lee SJ, Kim J, Seong H, Oh DH, Kim YC, Kim EJ, Jeong SJ, Ku NS, Choi JY, Song YG, Kim JM.

Medicine (Baltimore). 2017 Mar;96(11):e6332. doi: 10.1097/MD.0000000000006332.


Co-precipitation of rare-earth-doped Y<sub>2</sub>O<sub>3</sub> and MgO nanocomposites for mid-infrared solid-state lasers.

Blair VL, Fleischman ZD, Merkle LD, Ku N, Moorehead CA.

Appl Opt. 2017 Jan 20;56(3):B154-B158. doi: 10.1364/AO.56.00B154.


Long Pentraxin 3 as a Predictive Marker of Mortality in Severe Septic Patients Who Received Successful Early Goal-Directed Therapy.

Kim SB, Lee KH, Lee JU, Ann HW, Ahn JY, Jeon YD, Kim JH, Ku NS, Han SH, Choi JY, Song YG, Kim JM.

Yonsei Med J. 2017 Mar;58(2):370-379. doi: 10.3349/ymj.2017.58.2.370.


Successful Targeted Therapy of Refractory Pediatric ETV6-NTRK3 Fusion-Positive Secretory Breast Carcinoma.

Shukla N, Roberts SS, Baki MO, Mushtaq Q, Goss PE, Park BH, Gundem G, Tian K, Geiger H, Redfield K, Behr G, Benayed R, Zehir A, Hechtman JF, Darnell RB, Papaemmanuil E, Ladanyi M, Ku N, Kung AL, Baselga J, Drilon A, Hyman DM.

JCO Precis Oncol. 2017;2017. doi: 10.1200/PO.17.00034. Epub 2017 Aug 18. No abstract available.


Treatment Outcomes of Patients Treated for Pulmonary Tuberculosis after Undergoing Gastrectomy.

Jung IY, Kim MH, Jeong WY, Ahn MY, Jeon YD, Ahn HW, Ahn JY, Song JE, Oh DH, Kim YC, Kim EJ, Jeong SJ, Ku NS, Kim JM, Choi JY.

Tohoku J Exp Med. 2016 Dec;240(4):281-286.


Predictive factors for unfavorable outcomes of tuberculous pericarditis in human immunodeficiency virus-uninfected patients in an intermediate tuberculosis burden country.

Jung IY, Song YG, Choi JY, Kim MH, Jeong WY, Oh DH, Kim YC, Song JE, Kim EJ, Lee JU, Jeong SJ, Ku NS, Kim JM.

BMC Infect Dis. 2016 Nov 29;16(1):719.


Relative Prevalence and Antimicrobial Susceptibility of Clinical Isolates of Elizabethkingia Species Based on 16S rRNA Gene Sequencing.

Han MS, Kim H, Lee Y, Kim M, Ku NS, Choi JY, Yong D, Jeong SH, Lee K, Chong Y.

J Clin Microbiol. 2016 Dec 28;55(1):274-280. doi: 10.1128/JCM.01637-16. Print 2017 Jan.


A Case of Infective Endocarditis caused by Abiotrophia defectiva in Korea.

Park S, Ann HW, Ahn JY, Ku NS, Han SH, Hong GR, Choi JY, Song YG, Kim JM.

Infect Chemother. 2016 Sep;48(3):229-233. doi: 10.3947/ic.2016.48.3.229. Epub 2016 Sep 12.


Mortality Risk Factors for Patients with Septic Shock after Implementation of the Surviving Sepsis Campaign Bundles.

Song JE, Kim MH, Jeong WY, Jung IY, Oh DH, Kim YC, Kim EJ, Jeong SJ, Ku NS, Kim JM, Choi JY.

Infect Chemother. 2016 Sep;48(3):199-208. doi: 10.3947/ic.2016.48.3.199. Epub 2016 Sep 6.


Elevated CD8 T-cell counts and virological failure in HIV-infected patients after combination antiretroviral therapy.

Ku NS, Jiamsakul A, Ng OT, Yunihastuti E, Cuong do D, Lee MP, Sim BL, Phanuphak P, Wong WW, Kamarulzaman A, Zhang F, Pujari S, Chaiwarith R, Oka S, Mustafa M, Kumarasamy N, Van Nguyen K, Ditangco R, Kiertiburanakul S, Merati TP, Durier N, Choi JY; TREAT Asia HIV Observational Databases (TAHOD).

Medicine (Baltimore). 2016 Aug;95(32):e4570. doi: 10.1097/MD.0000000000004570.


Risk factors for mortality in patients with Stenotrophomonas maltophilia bacteremia.

Jeon YD, Jeong WY, Kim MH, Jung IY, Ahn MY, Ann HW, Ahn JY, Han SH, Choi JY, Song YG, Kim JM, Ku NS.

Medicine (Baltimore). 2016 Aug;95(31):e4375. doi: 10.1097/MD.0000000000004375.


Can early initiation of continuous renal replacement therapy improve patient survival with septic acute kidney injury when enrolled in early goal-directed therapy?

Oh HJ, Kim MH, Ahn JY, Ku NS, Park JT, Han SH, Choi JY, Han SH, Yoo TH, Song YG, Kang SW, Kim JM.

J Crit Care. 2016 Oct;35:51-6. doi: 10.1016/j.jcrc.2016.04.032. Epub 2016 May 4.


Predictive Factors of Spontaneous Bacterial Peritonitis Caused by Gram-Positive Bacteria in Patients With Cirrhosis.

Kim JH, Jeon YD, Jung IY, Ahn MY, Ahn HW, Ahn JY, Ku NS, Han SH, Choi JY, Ahn SH, Song YG, Han KH, Kim JM.

Medicine (Baltimore). 2016 Apr;95(17):e3489. doi: 10.1097/MD.0000000000003489.

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