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Items: 28


Entrectinib resistance mechanisms in ROS1-rearranged non-small cell lung cancer.

Ku BM, Bae YH, Lee KY, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ.

Invest New Drugs. 2019 May 24. doi: 10.1007/s10637-019-00795-3. [Epub ahead of print]


The First-week Proliferative Response of Peripheral Blood PD-1+CD8+ T Cells Predicts the Response to Anti-PD-1 Therapy in Solid Tumors.

Kim KH, Cho J, Ku BM, Koh J, Sun JM, Lee SH, Ahn JS, Cheon J, Min YJ, Park SH, Park K, Ahn MJ, Shin EC.

Clin Cancer Res. 2019 Apr 1;25(7):2144-2154. doi: 10.1158/1078-0432.CCR-18-1449. Epub 2019 Jan 15.


Pembrolizumab for Patients With Refractory or Relapsed Thymic Epithelial Tumor: An Open-Label Phase II Trial.

Cho J, Kim HS, Ku BM, Choi YL, Cristescu R, Han J, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ.

J Clin Oncol. 2018 Jun 15:JCO2017773184. doi: 10.1200/JCO.2017.77.3184. [Epub ahead of print]


Acquired resistance to AZD9291 as an upfront treatment is dependent on ERK signaling in a preclinical model.

Ku BM, Choi MK, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ.

PLoS One. 2018 Apr 11;13(4):e0194730. doi: 10.1371/journal.pone.0194730. eCollection 2018.


Molecular Screening of Small Biopsy Samples Using Next-Generation Sequencing in Korean Patients with Advanced Non-small Cell Lung Cancer: Korean Lung Cancer Consortium (KLCC-13-01).

Ku BM, Heo MH, Kim JH, Cho BC, Cho EK, Min YJ, Lee KH, Sun JM, Lee SH, Ahn JS, Park K, Kim TJ, Lee HY, Kim H, Lee KJ, Ahn MJ.

J Pathol Transl Med. 2018 May;52(3):148-156. doi: 10.4132/jptm.2018.03.12. Epub 2018 Mar 26.


KIF5B-MET Gene Rearrangement with Robust Antitumor Activity in Response to Crizotinib in Lung Adenocarcinoma.

Cho JH, Ku BM, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ.

J Thorac Oncol. 2018 Mar;13(3):e29-e31. doi: 10.1016/j.jtho.2017.10.014. Epub 2017 Nov 2. No abstract available.


Fluorescence-coded DNA Nanostructure Probe System to Enable Discrimination of Tumor Heterogeneity via a Screening of Dual Intracellular microRNA Signatures in situ.

Shin SW, Lee BS, Yang K, Amornkitbamrung L, Jang MS, Ku BM, Cho SW, Lee JH, Bae H, Oh BK, Ahn MJ, Lim YT, Um SH.

Sci Rep. 2017 Oct 18;7(1):13499. doi: 10.1038/s41598-017-13456-3.


Mutational status of TP53 defines the efficacy of Wee1 inhibitor AZD1775 in KRAS-mutant non-small cell lung cancer.

Ku BM, Bae YH, Koh J, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ.

Oncotarget. 2017 Jun 28;8(40):67526-67537. doi: 10.18632/oncotarget.18728. eCollection 2017 Sep 15.


An update on biomarkers for kinase inhibitor response in non-small-cell lung cancer.

Ku BM, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ.

Expert Rev Mol Diagn. 2017 Oct;17(10):933-942. doi: 10.1080/14737159.2017.1372196. Epub 2017 Aug 30. Review.


Genetic Alterations and Their Clinical Implications in High-Recurrence Risk Papillary Thyroid Cancer.

Lee MY, Ku BM, Kim HS, Lee JY, Lim SH, Sun JM, Lee SH, Park K, Oh YL, Hong M, Jeong HS, Son YI, Baek CH, Ahn MJ.

Cancer Res Treat. 2017 Oct;49(4):906-914. doi: 10.4143/crt.2016.424. Epub 2016 Dec 26.


AZD9291 overcomes T790 M-mediated resistance through degradation of EGFR(L858R/T790M) in non-small cell lung cancer cells.

Ku BM, Bae YH, Koh J, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ.

Invest New Drugs. 2016 Aug;34(4):407-15. doi: 10.1007/s10637-016-0350-y. Epub 2016 Apr 5.


The CDK4/6 inhibitor LY2835219 has potent activity in combination with mTOR inhibitor in head and neck squamous cell carcinoma.

Ku BM, Yi SY, Koh J, Bae YH, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ.

Oncotarget. 2016 Mar 22;7(12):14803-13. doi: 10.18632/oncotarget.7543.


A Phase Ib/II Study of Afatinib in Combination with Nimotuzumab in Non-Small Cell Lung Cancer Patients with Acquired Resistance to Gefitinib or Erlotinib.

Lee JY, Sun JM, Lim SH, Kim HS, Yoo KH, Jung KS, Song HN, Ku BM, Koh J, Bae YH, Lee SH, Ahn JS, Park K, Ahn MJ.

Clin Cancer Res. 2016 May 1;22(9):2139-45. doi: 10.1158/1078-0432.CCR-15-1653. Epub 2015 Dec 14.


The BIM Deletion Polymorphism and its Clinical Implication in Patients with EGFR-Mutant Non-Small-Cell Lung Cancer Treated with EGFR Tyrosine Kinase Inhibitors.

Lee JY, Ku BM, Lim SH, Lee MY, Kim H, Kim M, Kim S, Jung HA, Sun JM, Ahn JS, Park K, Ahn MJ.

J Thorac Oncol. 2015 Jun;10(6):903-9. doi: 10.1097/JTO.0000000000000535.


High-throughput profiling identifies clinically actionable mutations in salivary duct carcinoma.

Ku BM, Jung HA, Sun JM, Ko YH, Jeong HS, Son YI, Baek CH, Park K, Ahn MJ.

J Transl Med. 2014 Oct 25;12:299. doi: 10.1186/s12967-014-0299-6.


BYL719, a selective inhibitor of phosphoinositide 3-Kinase α, enhances the effect of selumetinib (AZD6244, ARRY-142886) in KRAS-mutant non-small cell lung cancer.

Ku BM, Jho EH, Bae YH, Sun JM, Ahn JS, Park K, Ahn MJ.

Invest New Drugs. 2015 Feb;33(1):12-21. doi: 10.1007/s10637-014-0163-9. Epub 2014 Oct 25.


Increased expression of transglutaminase 2 drives glycolytic metabolism in renal carcinoma cells.

Ku BM, Lee CH, Lee SH, Kim SY.

Amino Acids. 2014 Jun;46(6):1527-36. doi: 10.1007/s00726-014-1714-2. Epub 2014 Mar 19.


Transglutaminase 2 inhibitor abrogates renal cell carcinoma in xenograft models.

Ku BM, Kim SJ, Kim N, Hong D, Choi YB, Lee SH, Gong YD, Kim SY.

J Cancer Res Clin Oncol. 2014 May;140(5):757-67. doi: 10.1007/s00432-014-1623-5. Epub 2014 Mar 8.


PKCη Regulates the TGFβ3-induced Chondevrepogenic Differentiation of Human Mesenchymal Stem Cell.

Ku BM, Yune YP, Lee ES, Hah YS, Park JY, Jeong JY, Lee DH, Cho GJ, Choi WS, Kang SS.

Dev Reprod. 2013 Dec;17(4):299-309. doi: 10.12717/DR.2013.17.4.299.


Transglutaminase 2 inhibition found to induce p53 mediated apoptosis in renal cell carcinoma.

Ku BM, Kim DS, Kim KH, Yoo BC, Kim SH, Gong YD, Kim SY.

FASEB J. 2013 Sep;27(9):3487-95. doi: 10.1096/fj.12-224220. Epub 2013 May 23.


Resveratrol reduces TNF-α-induced U373MG human glioma cell invasion through regulating NF-κB activation and uPA/uPAR expression.

Ryu J, Ku BM, Lee YK, Jeong JY, Kang S, Choi J, Yang Y, Lee DH, Roh GS, Kim HJ, Cho GJ, Choi WS, Kim N, Kang SS.

Anticancer Res. 2011 Dec;31(12):4223-30.


Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells.

Ku BM, Lee YK, Jeong JY, Ryu J, Choi J, Kim JS, Cho YW, Roh GS, Kim HJ, Cho GJ, Choi WS, Kang SS.

Mol Cells. 2011 Mar;31(3):275-9. doi: 10.1007/s10059-011-0027-5. Epub 2010 Dec 30.


4'-Acetoamido-4-hydroxychalcone, a chalcone derivative, inhibits glioma growth and invasion through regulation of the tropomyosin 1 gene.

Ku BM, Ryu HW, Lee YK, Ryu J, Jeong JY, Choi J, Cho HJ, Park KH, Kang SS.

Biochem Biophys Res Commun. 2010 Nov 19;402(3):525-30. doi: 10.1016/j.bbrc.2010.10.068. Epub 2010 Oct 28.


CHI3L1 (YKL-40) is expressed in human gliomas and regulates the invasion, growth and survival of glioma cells.

Ku BM, Lee YK, Ryu J, Jeong JY, Choi J, Eun KM, Shin HY, Kim DG, Hwang EM, Yoo JC, Park JY, Roh GS, Kim HJ, Cho GJ, Choi WS, Paek SH, Kang SS.

Int J Cancer. 2011 Mar 15;128(6):1316-26. doi: 10.1002/ijc.25466.


Caffeine-mediated inhibition of calcium release channel inositol 1,4,5-trisphosphate receptor subtype 3 blocks glioblastoma invasion and extends survival.

Kang SS, Han KS, Ku BM, Lee YK, Hong J, Shin HY, Almonte AG, Woo DH, Brat DJ, Hwang EM, Yoo SH, Chung CK, Park SH, Paek SH, Roh EJ, Lee SJ, Park JY, Traynelis SF, Lee CJ.

Cancer Res. 2010 Feb 1;70(3):1173-83. doi: 10.1158/0008-5472.CAN-09-2886. Epub 2010 Jan 26.


Ethanol-induced oxidative stress is mediated by p38 MAPK pathway in mouse hippocampal cells.

Ku BM, Lee YK, Jeong JY, Mun J, Han JY, Roh GS, Kim HJ, Cho GJ, Choi WS, Yi GS, Kang SS.

Neurosci Lett. 2007 May 23;419(1):64-7. Epub 2007 Mar 28.


Acute ethanol administration decreases GAP-43 and phosphorylated-GAP-43 in the rat hippocampus.

Kim HJ, Choi KM, Ku BM, Mun J, Joo Y, Han JY, Kim YH, Roh GS, Kang SS, Cho GJ, Choi WS.

Brain Res. 2006 Sep 27;1112(1):16-25. Epub 2006 Aug 14.


Heme oxygenase protects hippocampal neurons from ethanol-induced neurotoxicity.

Ku BM, Joo Y, Mun J, Roh GS, Kang SS, Cho GJ, Choi WS, Kim HJ.

Neurosci Lett. 2006 Sep 25;405(3):168-71. Epub 2006 Jul 20.


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