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Items: 18


Systems Biology of Cancer Metastasis.

Suhail Y, Cain MP, Vanaja K, Kurywchak PA, Levchenko A, Kalluri R, Kshitiz.

Cell Syst. 2019 Aug 28;9(2):109-127. doi: 10.1016/j.cels.2019.07.003. Review.


Switch-like enhancement of epithelial-mesenchymal transition by YAP through feedback regulation of WT1 and Rho-family GTPases.

Park J, Kim DH, Shah SR, Kim HN, Kshitiz, Kim P, Quiñones-Hinojosa A, Levchenko A.

Nat Commun. 2019 Jun 26;10(1):2797. doi: 10.1038/s41467-019-10729-5.


Dynamic secretome of bone marrow-derived stromal cells reveals a cardioprotective biochemical cocktail.

Kshitiz, Ellison DD, Suhail Y, Afzal J, Woo L, Kilic O, Spees J, Levchenko A.

Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14374-14383. doi: 10.1073/pnas.1902598116. Epub 2019 Jun 25.


Biomechanical interplay between anisotropic re-organization of cells and the surrounding matrix underlies transition to invasive cancer spread.

Kim DH, Ewald AJ, Park J, Kshitiz, Kwak M, Gray RS, Su CY, Seo J, An SS, Levchenko A.

Sci Rep. 2018 Sep 21;8(1):14210. doi: 10.1038/s41598-018-32010-3.


Control of the interface between heterotypic cell populations reveals the mechanism of intercellular transfer of signaling proteins.

Kshitiz, Afzal J, Suhail Y, Ahn EH, Goyal R, Hubbi ME, Hussaini Q, Ellison DD, Goyal J, Nacev B, Kim DH, Lee JH, Frankel S, Gray K, Bankoti R, Chien AJ, Levchenko A.

Integr Biol (Camb). 2015 Mar;7(3):364-72.


A nanotopography approach for studying the structure-function relationships of cells and tissues.

Kshitiz, Afzal J, Kim SY, Kim DH.

Cell Adh Migr. 2015;9(4):300-7. Review.


Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression.

Hubbi ME, Gilkes DM, Hu H, Kshitiz, Ahmed I, Semenza GL.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3325-34. doi: 10.1073/pnas.1412840111. Epub 2014 Jul 28.


Concise review: Mechanotransduction via p190RhoGAP regulates a switch between cardiomyogenic and endothelial lineages in adult cardiac progenitors.

Kshitiz, Afzal J, Kim DH, Levchenko A.

Stem Cells. 2014 Aug;32(8):1999-2007. doi: 10.1002/stem.1700. Review.


Spatial control of adult stem cell fate using nanotopographic cues.

Ahn EH, Kim Y, Kshitiz, An SS, Afzal J, Lee S, Kwak M, Suh KY, Kim DH, Levchenko A.

Biomaterials. 2014 Mar;35(8):2401-2410. doi: 10.1016/j.biomaterials.2013.11.037. Epub 2013 Dec 31.


Sirtuin-7 inhibits the activity of hypoxia-inducible factors.

Hubbi ME, Hu H, Kshitiz, Gilkes DM, Semenza GL.

J Biol Chem. 2013 Jul 19;288(29):20768-75. doi: 10.1074/jbc.M113.476903. Epub 2013 Jun 9.


Chaperone-mediated autophagy targets hypoxia-inducible factor-1α (HIF-1α) for lysosomal degradation.

Hubbi ME, Hu H, Kshitiz, Ahmed I, Levchenko A, Semenza GL.

J Biol Chem. 2013 Apr 12;288(15):10703-14. doi: 10.1074/jbc.M112.414771. Epub 2013 Mar 1.


Modeling intercellular transfer of biomolecules through tunneling nanotubes.

Suhail Y, Kshitiz, Lee J, Walker M, Kim DH, Brennan MD, Bader JS, Levchenko A.

Bull Math Biol. 2013 Aug;75(8):1400-16. doi: 10.1007/s11538-013-9819-4. Epub 2013 Feb 16.


A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication.

Hubbi ME, Kshitiz, Gilkes DM, Rey S, Wong CC, Luo W, Kim DH, Dang CV, Levchenko A, Semenza GL.

Sci Signal. 2013 Feb 12;6(262):ra10. doi: 10.1126/scisignal.2003417.


Control of stem cell fate and function by engineering physical microenvironments.

Kshitiz, Park J, Kim P, Helen W, Engler AJ, Levchenko A, Kim DH.

Integr Biol (Camb). 2012 Sep;4(9):1008-18. Review.


Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration.

Kim DH, Kshitiz, Smith RR, Kim P, Ahn EH, Kim HN, Marbán E, Suh KY, Levchenko A.

Integr Biol (Camb). 2012 Sep;4(9):1019-33. doi: 10.1039/c2ib20067h. Epub 2012 Aug 13.


Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors.

Kshitiz, Hubbi ME, Ahn EH, Downey J, Afzal J, Kim DH, Rey S, Chang C, Kundu A, Semenza GL, Abraham RM, Levchenko A.

Sci Signal. 2012 Jun 5;5(227):ra41. doi: 10.1126/scisignal.2003002. Erratum in: Sci Signal. 2012 Oct 9;5(245):er6.


Cell motility of neural stem cells is reduced after SPIO-labeling, which is mitigated after exocytosis.

Cromer Berman SM, Kshitiz, Wang CJ, Orukari I, Levchenko A, Bulte JW, Walczak P.

Magn Reson Med. 2013 Jan;69(1):255-62. doi: 10.1002/mrm.24216. Epub 2012 Feb 28.


Micro- and nanoengineering for stem cell biology: the promise with a caution.

Kshitiz, Kim DH, Beebe DJ, Levchenko A.

Trends Biotechnol. 2011 Aug;29(8):399-408. doi: 10.1016/j.tibtech.2011.03.006. Epub 2011 May 5. Review.

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