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Items: 19


Cryptic genomic lesions in adverse-risk acute myeloid leukemia identified by integrated whole genome and transcriptome sequencing.

Kim JC, Zuzarte PC, Murphy T, Chan-Seng-Yue M, Brown AMK, Krzyzanowski PM, Smith AC, Notta F, Minden MD, McPherson JD.

Leukemia. 2019 Aug 21. doi: 10.1038/s41375-019-0546-1. [Epub ahead of print] No abstract available.


Combined EsophaCap cytology and MUC2 immunohistochemistry for screening of intestinal metaplasia, dysplasia and carcinoma.

Zhou Z, Kalatskaya I, Russell D, Marcon N, Cirocco M, Krzyzanowski PM, Streutker C, Liang H, Litle VR, Godfrey TE, Stein L.

Clin Exp Gastroenterol. 2019 May 15;12:219-229. doi: 10.2147/CEG.S186958. eCollection 2019.


Regional perturbation of gene transcription is associated with intrachromosomal rearrangements and gene fusion transcripts in high grade ovarian cancer.

Krzyzanowski PM, Sircoulomb F, Yousif F, Normand J, La Rose J, E Francis K, Suarez F, Beck T, McPherson JD, Stein LD, Rottapel RK.

Sci Rep. 2019 Mar 5;9(1):3590. doi: 10.1038/s41598-019-39878-9.


Plasma circulating tumor DNA as a potential tool for disease monitoring in head and neck cancer.

Egyud M, Sridhar P, Devaiah A, Yamada E, Saunders S, Ståhlberg A, Filges S, Krzyzanowski PM, Kalatskaya I, Jiao W, Stein LD, Jalisi S, Godfrey TE.

Head Neck. 2019 May;41(5):1351-1358. doi: 10.1002/hed.25563. Epub 2018 Dec 15.


Impact of Chemical-Induced Mutational Load Increase on Immune Checkpoint Therapy in Poorly Responsive Murine Tumors.

Kuczynski EA, Krueger J, Chow A, Xu P, Man S, Sundaravadanam Y, Miller JK, Krzyzanowski PM, Kerbel RS.

Mol Cancer Ther. 2018 Apr;17(4):869-882. doi: 10.1158/1535-7163.MCT-17-1091. Epub 2018 Feb 26.


Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial.

Aung KL, Fischer SE, Denroche RE, Jang GH, Dodd A, Creighton S, Southwood B, Liang SB, Chadwick D, Zhang A, O'Kane GM, Albaba H, Moura S, Grant RC, Miller JK, Mbabaali F, Pasternack D, Lungu IM, Bartlett JMS, Ghai S, Lemire M, Holter S, Connor AA, Moffitt RA, Yeh JJ, Timms L, Krzyzanowski PM, Dhani N, Hedley D, Notta F, Wilson JM, Moore MJ, Gallinger S, Knox JJ.

Clin Cancer Res. 2018 Mar 15;24(6):1344-1354. doi: 10.1158/1078-0432.CCR-17-2994. Epub 2017 Dec 29.


Simple multiplexed PCR-based barcoding of DNA for ultrasensitive mutation detection by next-generation sequencing.

Ståhlberg A, Krzyzanowski PM, Egyud M, Filges S, Stein L, Godfrey TE.

Nat Protoc. 2017 Apr;12(4):664-682. doi: 10.1038/nprot.2017.006. Epub 2017 Mar 2.


Simple, multiplexed, PCR-based barcoding of DNA enables sensitive mutation detection in liquid biopsies using sequencing.

Ståhlberg A, Krzyzanowski PM, Jackson JB, Egyud M, Stein L, Godfrey TE.

Nucleic Acids Res. 2016 Jun 20;44(11):e105. doi: 10.1093/nar/gkw224. Epub 2016 Apr 7.


Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer.

Braunstein M, Liao L, Lyttle N, Lobo N, Taylor KJ, Krzyzanowski PM, Kalatskaya I, Yao CQ, Stein LD, Boutros PC, Twelves CJ, Marcellus R, Bartlett JM, Spears M.

Breast Cancer Res. 2016 Feb 6;18(1):16. doi: 10.1186/s13058-016-0676-6.


CaPSID: a bioinformatics platform for computational pathogen sequence identification in human genomes and transcriptomes.

Borozan I, Wilson S, Blanchette P, Laflamme P, Watt SN, Krzyzanowski PM, Sircoulomb F, Rottapel R, Branton PE, Ferretti V.

BMC Bioinformatics. 2012 Aug 17;13:206. doi: 10.1186/1471-2105-13-206.


Essential gene profiles in breast, pancreatic, and ovarian cancer cells.

Marcotte R, Brown KR, Suarez F, Sayad A, Karamboulas K, Krzyzanowski PM, Sircoulomb F, Medrano M, Fedyshyn Y, Koh JLY, van Dyk D, Fedyshyn B, Luhova M, Brito GC, Vizeacoumar FJ, Vizeacoumar FS, Datti A, Kasimer D, Buzina A, Mero P, Misquitta C, Normand J, Haider M, Ketela T, Wrana JL, Rottapel R, Neel BG, Moffat J.

Cancer Discov. 2012 Feb;2(2):172-189. doi: 10.1158/2159-8290.CD-11-0224. Epub 2011 Dec 29.


Computational approaches to discovering noncoding RNA.

Krzyzanowski PM, Muro EM, Andrade-Navarro MA.

Wiley Interdiscip Rev RNA. 2012 Jul-Aug;3(4):567-79. doi: 10.1002/wrna.1121. Epub 2012 May 3. Review.


Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism.

Levaot N, Voytyuk O, Dimitriou I, Sircoulomb F, Chandrakumar A, Deckert M, Krzyzanowski PM, Scotter A, Gu S, Janmohamed S, Cong F, Simoncic PD, Ueki Y, La Rose J, Rottapel R.

Cell. 2011 Dec 9;147(6):1324-39. doi: 10.1016/j.cell.2011.10.045.


Integration of expressed sequence tag data flanking predicted RNA secondary structures facilitates novel non-coding RNA discovery.

Krzyzanowski PM, Price FD, Muro EM, Rudnicki MA, Andrade-Navarro MA.

PLoS One. 2011;6(6):e20561. doi: 10.1371/journal.pone.0020561. Epub 2011 Jun 15.


Recent developments in StemBase: a tool to study gene expression in human and murine stem cells.

Sandie R, Palidwor GA, Huska MR, Porter CJ, Krzyzanowski PM, Muro EM, Perez-Iratxeta C, Andrade-Navarro MA.

BMC Res Notes. 2009 Mar 10;2:39. doi: 10.1186/1756-0500-2-39.


StemBase: a resource for the analysis of stem cell gene expression data.

Porter CJ, Palidwor GA, Sandie R, Krzyzanowski PM, Muro EM, Perez-Iratxeta C, Andrade-Navarro MA.

Methods Mol Biol. 2007;407:137-48. doi: 10.1007/978-1-59745-536-7_11.


Identification of novel stem cell markers using gap analysis of gene expression data.

Krzyzanowski PM, Andrade-Navarro MA.

Genome Biol. 2007;8(9):R193.


Protection of glioblastoma cells from cisplatin cytotoxicity via protein kinase Ciota-mediated attenuation of p38 MAP kinase signaling.

Baldwin RM, Garratt-Lalonde M, Parolin DA, Krzyzanowski PM, Andrade MA, Lorimer IA.

Oncogene. 2006 May 11;25(20):2909-19.


Study of stem cell function using microarray experiments.

Perez-Iratxeta C, Palidwor G, Porter CJ, Sanche NA, Huska MR, Suomela BP, Muro EM, Krzyzanowski PM, Hughes E, Campbell PA, Rudnicki MA, Andrade MA.

FEBS Lett. 2005 Mar 21;579(8):1795-801. Review.

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