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Pretreatment Prevotella-to-Bacteroides ratio and salivary amylase gene copy number as prognostic markers for dietary weight loss.

Hjorth MF, Christensen L, Larsen TM, Roager HM, Krych L, Kot W, Nielsen DS, Ritz C, Astrup A.

Am J Clin Nutr. 2020 Feb 7. pii: nqaa007. doi: 10.1093/ajcn/nqaa007. [Epub ahead of print]


Physical fitness in community-dwelling older adults is linked to dietary intake, gut microbiota, and metabolomic signatures.

Castro-Mejía JL, Khakimov B, Krych Ł, Bülow J, Bechshøft RL, Højfeldt G, Mertz KH, Garne ES, Schacht SR, Ahmad HF, Kot W, Hansen LH, Perez-Cueto FJA, Lind MV, Lassen AJ, Tetens I, Jensen T, Reitelseder S, Jespersen AP, Holm L, Engelsen SB, Nielsen DS.

Aging Cell. 2020 Jan 22:e13105. doi: 10.1111/acel.13105. [Epub ahead of print]


Restitution of gut microbiota in Ugandan children administered with probiotics (Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12) during treatment for severe acute malnutrition.

Castro-Mejía JL, O'Ferrall S, Krych Ł, O'Mahony E, Namusoke H, Lanyero B, Kot W, Nabukeera-Barungi N, Michaelsen KF, Mølgaard C, Friis H, Grenov B, Nielsen DS.

Gut Microbes. 2020 Jan 20:1-13. doi: 10.1080/19490976.2020.1712982. [Epub ahead of print] Erratum in: Gut Microbes. 2020 Jan 29;:1.


Impact of Dietary Supplementation of Lactic Acid Bacteria Fermented Rapeseed with or without Macroalgae on Performance and Health of Piglets Following Omission of Medicinal Zinc from Weaner Diets.

Satessa GD, Tamez-Hidalgo P, Hui Y, Cieplak T, Krych L, Kjærulff S, Brunsgaard G, Nielsen DS, Nielsen MO.

Animals (Basel). 2020 Jan 15;10(1). pii: E137. doi: 10.3390/ani10010137.


Severe gut microbiota dysbiosis caused by malnourishment can be partly restored during 3 weeks of refeeding with fortified corn-soy-blend in a piglet model of childhood malnutrition.

Leng B, Sørensen MB, Kot W, Thymann T, Krych L, Nielsen DS.

BMC Microbiol. 2019 Dec 10;19(1):277. doi: 10.1186/s12866-019-1658-5.


DNA enrichment and tagmentation method for species-level identification and strain-level differentiation using ON-rep-seq.

Krych Ł, Castro-Mejía JL, Forero-Junco LM, Moesby DN, Mikkelsen MB, Rasmussen MA, Sykulski M, Nielsen DS.

Commun Biol. 2019 Oct 10;2:369. doi: 10.1038/s42003-019-0617-x. eCollection 2019.


Development of the equine gut microbiota.

Lindenberg F, Krych L, Kot W, Fielden J, Frøkiær H, van Galen G, Nielsen DS, Hansen AK.

Sci Rep. 2019 Oct 8;9(1):14427. doi: 10.1038/s41598-019-50563-9.


Cesarean section increases sensitivity to oxazolone-induced colitis in C57BL/6 mice.

Zachariassen LF, Hansen AK, Krych L, Nielsen DS, Holm TL, Tougaard P, Hansen CHF.

Mucosal Immunol. 2019 Nov;12(6):1348-1357. doi: 10.1038/s41385-019-0207-8. Epub 2019 Sep 25.


Effect of potato fiber on survival of Lactobacillus species at simulated gastric conditions and composition of the gut microbiota in vitro.

Larsen N, de Souza CB, Krych L, Kot W, Leser TD, Sørensen OB, Blennow A, Venema K, Jespersen L.

Food Res Int. 2019 Nov;125:108644. doi: 10.1016/j.foodres.2019.108644. Epub 2019 Aug 24.


Prevotella Abundance Predicts Weight Loss Success in Healthy, Overweight Adults Consuming a Whole-Grain Diet Ad Libitum: A Post Hoc Analysis of a 6-Wk Randomized Controlled Trial.

Christensen L, Vuholm S, Roager HM, Nielsen DS, Krych L, Kristensen M, Astrup A, Hjorth MF.

J Nutr. 2019 Dec 1;149(12):2174-2181. doi: 10.1093/jn/nxz198.


Expression of immune regulatory genes correlate with the abundance of specific Clostridiales and Verrucomicrobia species in the equine ileum and cecum.

Lindenberg F, Krych L, Fielden J, Kot W, Frøkiær H, van Galen G, Nielsen DS, Hansen AK.

Sci Rep. 2019 Sep 3;9(1):12674. doi: 10.1038/s41598-019-49081-5.


Prebiotic Effect of Lycopene and Dark Chocolate on Gut Microbiome with Systemic Changes in Liver Metabolism, Skeletal Muscles and Skin in Moderately Obese Persons.

Wiese M, Bashmakov Y, Chalyk N, Nielsen DS, Krych Ł, Kot W, Klochkov V, Pristensky D, Bandaletova T, Chernyshova M, Kyle N, Petyaev I.

Biomed Res Int. 2019 Jun 2;2019:4625279. doi: 10.1155/2019/4625279. eCollection 2019.


Linking cocoa varietals and microbial diversity of Nicaraguan fine cocoa bean fermentations and their impact on final cocoa quality appreciation.

Papalexandratou Z, Kaasik K, Kauffmann LV, Skorstengaard A, Bouillon G, Espensen JL, Hansen LH, Jakobsen RR, Blennow A, Krych L, Castro-Mejía JL, Nielsen DS.

Int J Food Microbiol. 2019 Sep 2;304:106-118. doi: 10.1016/j.ijfoodmicro.2019.05.012. Epub 2019 Jun 2.


Targeting gut microbiota and barrier function with prebiotics to alleviate autoimmune manifestations in NOD mice.

Hansen CHF, Larsen CS, Petersson HO, Zachariassen LF, Vegge A, Lauridsen C, Kot W, Krych Ł, Nielsen DS, Hansen AK.

Diabetologia. 2019 Sep;62(9):1689-1700. doi: 10.1007/s00125-019-4910-5. Epub 2019 May 28.


Bacterial species to be considered in quality assurance of mice and rats.

Hansen AK, Nielsen DS, Krych L, Hansen CHF.

Lab Anim. 2019 Jun;53(3):281-291. doi: 10.1177/0023677219834324. Review.


Impact of Early Exposure to Cefuroxime on the Composition of the Gut Microbiota in Infants Following Cesarean Delivery.

Kamal SS, Hyldig N, Krych Ł, Greisen G, Krogfelt KA, Zachariassen G, Nielsen DS.

J Pediatr. 2019 Jul;210:99-105.e2. doi: 10.1016/j.jpeds.2019.03.001. Epub 2019 Apr 30.


Oral LPS Dosing Induces Local Immunological Changes in the Pancreatic Lymph Nodes in Mice.

Kihl P, Krych L, Deng L, Kildemoes AO, Laigaard A, Hansen LH, Hansen CHF, Buschard K, Nielsen DS, Hansen AK.

J Diabetes Res. 2019 Mar 6;2019:1649279. doi: 10.1155/2019/1649279. eCollection 2019.


Potential of Pectins to Beneficially Modulate the Gut Microbiota Depends on Their Structural Properties.

Larsen N, Bussolo de Souza C, Krych L, Barbosa Cahú T, Wiese M, Kot W, Hansen KM, Blennow A, Venema K, Jespersen L.

Front Microbiol. 2019 Feb 15;10:223. doi: 10.3389/fmicb.2019.00223. eCollection 2019.


Preterm Birth Has Effects on Gut Colonization in Piglets Within the First 4 Weeks of Life.

Kamal SS, Andersen AD, Krych L, Lauridsen C, Sangild PT, Thymann T, Nielsen DS.

J Pediatr Gastroenterol Nutr. 2019 May;68(5):727-733. doi: 10.1097/MPG.0000000000002259.


Cesarean Section Induces Microbiota-Regulated Immune Disturbances in C57BL/6 Mice.

Zachariassen LF, Krych L, Rasmussen SH, Nielsen DS, Kot W, Holm TL, Hansen AK, Hansen CHF.

J Immunol. 2019 Jan 1;202(1):142-150. doi: 10.4049/jimmunol.1800666. Epub 2018 Nov 28.


TL1A Aggravates Cytokine-Induced Acute Gut Inflammation and Potentiates Infiltration of Intraepithelial Natural Killer Cells in Mice.

Tougaard P, Martinsen LO, Zachariassen LF, Krych L, Nielsen DS, Buus TB, Pedersen AE, Hansen AK, Skov S, Hansen CHF.

Inflamm Bowel Dis. 2019 Feb 21;25(3):510-523. doi: 10.1093/ibd/izy351.


Colonization of Cutibacterium avidum during infant gut microbiota establishment.

Rocha Martin VN, Schwab C, Krych L, Voney E, Geirnaert A, Braegger C, Lacroix C.

FEMS Microbiol Ecol. 2019 Jan 1;95(1). doi: 10.1093/femsec/fiy215.


Changes in Gut Microbiota Prior to Influenza A Virus Infection Do Not Affect Immune Responses in Pups or Juvenile Mice.

Fuglsang E, Pizzolla A, Krych L, Nielsen DS, Brooks AG, Frøkiær H, Reading PC.

Front Cell Infect Microbiol. 2018 Sep 12;8:319. doi: 10.3389/fcimb.2018.00319. eCollection 2018.


Lacto-fermented sauerkraut improves symptoms in IBS patients independent of product pasteurisation - a pilot study.

Nielsen ES, Garnås E, Jensen KJ, Hansen LH, Olsen PS, Ritz C, Krych L, Nielsen DS.

Food Funct. 2018 Oct 17;9(10):5323-5335. doi: 10.1039/c8fo00968f.


Postnatal Administration of Lactobacillus rhamnosus HN001 Ameliorates Perinatal Broad-Spectrum Antibiotic-Induced Reduction in Myelopoiesis and T Cell Activation in Mouse Pups.

Fuglsang E, Krych L, Lundsager MT, Nielsen DS, Frøkiaer H.

Mol Nutr Food Res. 2018 Nov;62(22):e1800510. doi: 10.1002/mnfr.201800510. Epub 2018 Oct 4.


Cheese brines from Danish dairies reveal a complex microbiota comprising several halotolerant bacteria and yeasts.

Haastrup MK, Johansen P, Malskær AH, Castro-Mejía JL, Kot W, Krych L, Arneborg N, Jespersen L.

Int J Food Microbiol. 2018 Nov 20;285:173-187. doi: 10.1016/j.ijfoodmicro.2018.08.015. Epub 2018 Aug 23.


Effect of the dietary polyacetylenes falcarinol and falcarindiol on the gut microbiota composition in a rat model of colorectal cancer.

Kobaek-Larsen M, Nielsen DS, Kot W, Krych Ł, Christensen LP, Baatrup G.

BMC Res Notes. 2018 Jun 27;11(1):411. doi: 10.1186/s13104-018-3527-y.


Gut microbiota recovery and immune response in ampicillin-treated mice.

Castro-Mejía JL, Jakesevic M, Fabricius NF, Krych Ł, Nielsen DS, Kot W, Bendtsen KM, Vogensen FK, Hansen CHF, Hansen AK.

Res Vet Sci. 2018 Jun;118:357-364. doi: 10.1016/j.rvsc.2018.03.013. Epub 2018 Mar 27.


Oral insulin does not alter gut microbiota composition of NOD mice.

Kihl P, Krych L, Buschard K, Wesley JD, Kot W, Hansen AK, Nielsen DS, von Herrath MG.

Diabetes Metab Res Rev. 2018 Sep;34(6):e3010. doi: 10.1002/dmrr.3010. Epub 2018 May 1.


Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics.

Rune I, Rolin B, Lykkesfeldt J, Nielsen DS, Krych Ł, Kanter JE, Bornfeldt KE, Kihl P, Buschard K, Josefsen K, Fels JJ, Mortensen A, Christoffersen B, Kirk RK, Hansen AK.

Sci Rep. 2018 Apr 3;8(1):5416. doi: 10.1038/s41598-018-23835-z.


Understanding the prebiotic potential of different dietary fibers using an in vitro continuous adult fermentation model (PolyFermS).

Poeker SA, Geirnaert A, Berchtold L, Greppi A, Krych L, Steinert RE, de Wouters T, Lacroix C.

Sci Rep. 2018 Mar 12;8(1):4318. doi: 10.1038/s41598-018-22438-y.


Have you tried spermine? A rapid and cost-effective method to eliminate dextran sodium sulfate inhibition of PCR and RT-PCR.

Krych Ł, Kot W, Bendtsen KMB, Hansen AK, Vogensen FK, Nielsen DS.

J Microbiol Methods. 2018 Jan;144:1-7. doi: 10.1016/j.mimet.2017.10.015. Epub 2017 Oct 28.


A polyphenol-enriched diet and Ascaris suum infection modulate mucosal immune responses and gut microbiota composition in pigs.

Williams AR, Krych L, Fauzan Ahmad H, Nejsum P, Skovgaard K, Nielsen DS, Thamsborg SM.

PLoS One. 2017 Oct 13;12(10):e0186546. doi: 10.1371/journal.pone.0186546. eCollection 2017.


Whole-Grain Rye and Wheat Affect Some Markers of Gut Health without Altering the Fecal Microbiota in Healthy Overweight Adults: A 6-Week Randomized Trial.

Vuholm S, Nielsen DS, Iversen KN, Suhr J, Westermann P, Krych L, Andersen JR, Kristensen M.

J Nutr. 2017 Nov;147(11):2067-2075. doi: 10.3945/jn.117.250647. Epub 2017 Sep 27.


Effect of Early-life Gut Mucosal Compromise on Disease Progression in NOD Mice.

Bendtsen KM, Hansen CH, Krych L, Buschard K, Farlov H, Hansen AK.

Comp Med. 2017 Oct 1;67(5):388-399.


Metagenomic Analysis of Dairy Bacteriophages: Extraction Method and Pilot Study on Whey Samples Derived from Using Undefined and Defined Mesophilic Starter Cultures.

Muhammed MK, Kot W, Neve H, Mahony J, Castro-Mejía JL, Krych L, Hansen LH, Nielsen DS, Sørensen SJ, Heller KJ, van Sinderen D, Vogensen FK.

Appl Environ Microbiol. 2017 Sep 15;83(19). pii: e00888-17. doi: 10.1128/AEM.00888-17. Print 2017 Oct 1.


Dietary cinnamaldehyde enhances acquisition of specific antibodies following helminth infection in pigs.

Williams AR, Hansen TVA, Krych L, Ahmad HFB, Nielsen DS, Skovgaard K, Thamsborg SM.

Vet Immunol Immunopathol. 2017 Jul;189:43-52. doi: 10.1016/j.vetimm.2017.06.004. Epub 2017 Jun 17.


Immunological effects of reduced mucosal integrity in the early life of BALB/c mice.

Bendtsen KM, Hansen CHF, Krych Ł, Skovgaard K, Kot W, Vogensen FK, Hansen AK.

PLoS One. 2017 May 1;12(5):e0176662. doi: 10.1371/journal.pone.0176662. eCollection 2017.


A high-throughput qPCR system for simultaneous quantitative detection of dairy Lactococcus lactis and Leuconostoc bacteriophages.

Muhammed MK, Krych L, Nielsen DS, Vogensen FK.

PLoS One. 2017 Mar 24;12(3):e0174223. doi: 10.1371/journal.pone.0174223. eCollection 2017.


Sensitivity to oxazolone induced dermatitis is transferable with gut microbiota in mice.

Zachariassen LF, Krych L, Engkilde K, Nielsen DS, Kot W, Hansen CH, Hansen AK.

Sci Rep. 2017 Mar 14;7:44385. doi: 10.1038/srep44385.


Fermentation of African kale (Brassica carinata) using L. plantarum BFE 5092 and L. fermentum BFE 6620 starter strains.

Oguntoyinbo FA, Cho GS, Trierweiler B, Kabisch J, Rösch N, Neve H, Bockelmann W, Frommherz L, Nielsen DS, Krych L, Franz CM.

Int J Food Microbiol. 2016 Dec 5;238:103-112. doi: 10.1016/j.ijfoodmicro.2016.08.030. Epub 2016 Aug 24.


Minimal short-term effect of dietary 2'-fucosyllactose on bacterial colonisation, intestinal function and necrotising enterocolitis in preterm pigs.

Cilieborg MS, Bering SB, Østergaard MV, Jensen ML, Krych Ł, Newburg DS, Sangild PT.

Br J Nutr. 2016 Sep;116(5):834-41. doi: 10.1017/S0007114516002646. Epub 2016 Jul 25.


Treatment with a Monoclonal Anti-IL-12p40 Antibody Induces Substantial Gut Microbiota Changes in an Experimental Colitis Model.

Castro-Mejía J, Jakesevic M, Krych Ł, Nielsen DS, Hansen LH, Sondergaard BC, Kvist PH, Hansen AK, Holm TL.

Gastroenterol Res Pract. 2016;2016:4953120. doi: 10.1155/2016/4953120. Epub 2016 Jan 6.


Colonic Lesions, Cytokine Profiles, and Gut Microbiota in Plasminogen-Deficient Mice.

Vestergaard B, Krych Ł, Lund LR, Jørgensen BP, Hansen L, Jensen HE, Nielsen DS, Hansen AK.

Comp Med. 2015 Oct;65(5):382-97.


A Review of Applied Aspects of Dealing with Gut Microbiota Impact on Rodent Models.

Hansen AK, Krych Ł, Nielsen DS, Hansen CH.

ILAR J. 2015;56(2):250-64. doi: 10.1093/ilar/ilv010. Review.


Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs.

Shen RL, Thymann T, Østergaard MV, Støy AC, Krych Ł, Nielsen DS, Lauridsen C, Hartmann B, Holst JJ, Burrin DG, Sangild PT.

Am J Physiol Gastrointest Liver Physiol. 2015 Sep 1;309(5):G310-23. doi: 10.1152/ajpgi.00163.2015. Epub 2015 Jul 2.


Introducing enteral feeding induces intestinal subclinical inflammation and respective chromatin changes in preterm pigs.

Willems R, Krych L, Rybicki V, Jiang P, Sangild PT, Shen RL, Hensel KO, Wirth S, Postberg J, Jenke AC.

Epigenomics. 2015;7(4):553-65. doi: 10.2217/epi.15.13. Erratum in: Epigenomics. 2015 Aug;7(5):876.


Endocannabinoid-mediated improvement on a test of aversive memory in a mouse model of fragile X syndrome.

Qin M, Zeidler Z, Moulton K, Krych L, Xia Z, Smith CB.

Behav Brain Res. 2015 Sep 15;291:164-171. doi: 10.1016/j.bbr.2015.05.003. Epub 2015 May 12.


Phytase-producing capacity of yeasts isolated from traditional African fermented food products and PHYPk gene expression of Pichia kudriavzevii strains.

Greppi A, Krych Ł, Costantini A, Rantsiou K, Hounhouigan DJ, Arneborg N, Cocolin L, Jespersen L.

Int J Food Microbiol. 2015 Jul 16;205:81-9. doi: 10.1016/j.ijfoodmicro.2015.04.011. Epub 2015 Apr 9.


R-Baclofen Reverses a Social Behavior Deficit and Elevated Protein Synthesis in a Mouse Model of Fragile X Syndrome.

Qin M, Huang T, Kader M, Krych L, Xia Z, Burlin T, Zeidler Z, Zhao T, Smith CB.

Int J Neuropsychopharmacol. 2015 Mar 28;18(9). pii: pyv034. doi: 10.1093/ijnp/pyv034.

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