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Correction to: The AHR represses nucleotide excision repair and apoptosis and contributes to UV-induced skin carcinogenesis.

Pollet M, Shaik S, Mescher M, Frauenstein K, Tigges J, Braun SA, Sondenheimer K, Kaveh M, Bruhs A, Meller S, Homey B, Schwarz A, Esser C, Douki T, Vogel CFA, Krutmann J, Haarmann-Stemmann T.

Cell Death Differ. 2019 Oct 22. doi: 10.1038/s41418-019-0440-4. [Epub ahead of print]


Genome-wide scan identified genetic variants associated with skin aging in a Chinese female population.

Liu Y, Gao W, Koellmann C, Le Clerc S, Hüls A, Li B, Peng Q, Wu S, Ding A, Yang Y, Jin L, Krutmann J, Schikowski T, Zagury JF, Wang S.

J Dermatol Sci. 2019 Oct;96(1):42-49. doi: 10.1016/j.jdermsci.2019.08.010. Epub 2019 Sep 6.


Autologous Cell Therapy for Aged Human Skin: A Randomized, Placebo-Controlled, Phase-I Study.

Grether-Beck S, Marini A, Jaenicke T, Goessens-Rück P, McElwee KJ, Hoffmann R, Krutmann J.

Skin Pharmacol Physiol. 2019 Sep 11:1-8. doi: 10.1159/000502240. [Epub ahead of print]


Linear and exponential sunscreen behaviours as an explanation for observed discrepancies in sun protection factor testing.

Trullàs C, Granger C, Lim HW, Krutmann J, Masson P.

Photodermatol Photoimmunol Photomed. 2019 Aug 3. doi: 10.1111/phpp.12500. [Epub ahead of print]


New Methodology to Evaluate Sunscreens Under Outdoor Conditions: A Double-Blind, Randomized Intra-Individual Clinical Study of a Water-Based Broad-Spectrum SPF50+ Versus SPF15 (P3) and SPF50.

Granger C, Krutmann J, Bustos J, Sola Y, Hosenally M, Trullàs C, Andres P, Passeron T.

Dermatol Ther (Heidelb). 2019 Sep;9(3):589-599. doi: 10.1007/s13555-019-00315-4. Epub 2019 Jul 27.


Beyond sequencing: fast and easy microbiome profiling by flow cytometry.

Esser C, Hochrath K, Teichweyde N, Krutmann J, Chang HD.

Arch Toxicol. 2019 Sep;93(9):2703-2704. doi: 10.1007/s00204-019-02527-1. Epub 2019 Jul 20. No abstract available.


Vemurafenib acts as an aryl hydrocarbon receptor antagonist: Implications for inflammatory cutaneous adverse events.

Hawerkamp HC, Kislat A, Gerber PA, Pollet M, Rolfes KM, Soshilov AA, Denison MS, Momin AA, Arold ST, Datsi A, Braun SA, Oláh P, Lacouture ME, Krutmann J, Haarmann-Stemmann T, Homey B, Meller S.

Allergy. 2019 Jul 3. doi: 10.1111/all.13972. [Epub ahead of print]


Photoimmunology: how ultraviolet radiation affects the immune system.

Bernard JJ, Gallo RL, Krutmann J.

Nat Rev Immunol. 2019 Nov;19(11):688-701. doi: 10.1038/s41577-019-0185-9. Epub 2019 Jun 18. Review.


The Toll-like receptor agonist imiquimod is metabolized by aryl hydrocarbon receptor-regulated cytochrome P450 enzymes in human keratinocytes and mouse liver.

Mescher M, Tigges J, Rolfes KM, Shen AL, Yee JS, Vogeley C, Krutmann J, Bradfield CA, Lang D, Haarmann-Stemmann T.

Arch Toxicol. 2019 Jul;93(7):1917-1926. doi: 10.1007/s00204-019-02488-5. Epub 2019 May 20.


[Air pollution and the skin].

Krutmann J.

Hautarzt. 2019 Mar;70(3):156-157. doi: 10.1007/s00105-018-4349-5. German. No abstract available.


Tomato Phytonutrients Balance UV Response: Results from a Double-Blind, Randomized, Placebo-Controlled Study.

Groten K, Marini A, Grether-Beck S, Jaenicke T, Ibbotson SH, Moseley H, Ferguson J, Krutmann J.

Skin Pharmacol Physiol. 2019;32(2):101-108. doi: 10.1159/000497104. Epub 2019 Mar 5.


Tropospheric ozone and skin aging: Results from two German cohort studies.

Fuks KB, Hüls A, Sugiri D, Altug H, Vierkötter A, Abramson MJ, Goebel J, Wagner GG, Demuth I, Krutmann J, Schikowski T.

Environ Int. 2019 Mar;124:139-144. doi: 10.1016/j.envint.2018.12.047. Epub 2019 Jan 11.


[Air pollution (particulate matter and nitrogen dioxide) and skin aging].

Schikowski T, Krutmann J.

Hautarzt. 2019 Mar;70(3):158-162. doi: 10.1007/s00105-018-4338-8. Review. German.


Lentigine Formation in Caucasian Women-Interaction between Particulate Matter and Solar UVR.

Hüls A, Sugiri D, Fuks K, Krutmann J, Schikowski T.

J Invest Dermatol. 2019 Apr;139(4):974-976. doi: 10.1016/j.jid.2018.09.034. Epub 2018 Nov 4. No abstract available.


Nonatopic eczema in elderly women: Effect of air pollution and genes.

Hüls A, Abramson MJ, Sugiri D, Fuks K, Krämer U, Krutmann J, Schikowski T.

J Allergy Clin Immunol. 2019 Jan;143(1):378-385.e9. doi: 10.1016/j.jaci.2018.09.031. Epub 2018 Oct 16.


Correction: SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy.

Lang A, Anand R, Altinoluk-Hambüchen S, Ezzahoini H, Stefanski A, Iram A, Bergmann L, Urbach J, Böhler P, Hänsel J, Franke M, Stühler K, Krutmann J, Scheller J, Stork B, Reichert AS, Piekorz RP.

Aging (Albany NY). 2018 Sep 28;10(9):2536c. doi: 10.18632/aging.101570. No abstract available.


Genome-wide association studies and CRISPR/Cas9-mediated gene editing identify regulatory variants influencing eyebrow thickness in humans.

Wu S, Zhang M, Yang X, Peng F, Zhang J, Tan J, Yang Y, Wang L, Hu Y, Peng Q, Li J, Liu Y, Guan Y, Chen C, Hamer MA, Nijsten T, Zeng C, Adhikari K, Gallo C, Poletti G, Schuler-Faccini L, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, González-José R, Li H, Krutmann J, Liu F, Kayser M, Ruiz-Linares A, Tang K, Xu S, Zhang L, Jin L, Wang S.

PLoS Genet. 2018 Sep 24;14(9):e1007640. doi: 10.1371/journal.pgen.1007640. eCollection 2018 Sep.


Novel Facial Cream Containing Carnosine Inhibits Formation of Advanced Glycation End-Products in Human Skin.

Narda M, Peno-Mazzarino L, Krutmann J, Trullas C, Granger C.

Skin Pharmacol Physiol. 2018;31(6):324-331. doi: 10.1159/000492276. Epub 2018 Sep 10.


Commentary: Usage of Mitogen-Activated Protein Kinase Small Molecule Inhibitors: More Than Just Inhibition!

Pollet M, Krutmann J, Haarmann-Stemmann T.

Front Pharmacol. 2018 Aug 20;9:935. doi: 10.3389/fphar.2018.00935. eCollection 2018. No abstract available.


HDAC inhibition improves autophagic and lysosomal function to prevent loss of subcutaneous fat in a mouse model of Cockayne syndrome.

Majora M, Sondenheimer K, Knechten M, Uthe I, Esser C, Schiavi A, Ventura N, Krutmann J.

Sci Transl Med. 2018 Aug 29;10(456). pii: eaam7510. doi: 10.1126/scitranslmed.aam7510.


The AHR represses nucleotide excision repair and apoptosis and contributes to UV-induced skin carcinogenesis.

Pollet M, Shaik S, Mescher M, Frauenstein K, Tigges J, Braun SA, Sondenheimer K, Kaveh M, Bruhs A, Meller S, Homey B, Schwarz A, Esser C, Douki T, Vogel CFA, Krutmann J, Haarmann-Stemmann T.

Cell Death Differ. 2018 Nov;25(10):1823-1836. doi: 10.1038/s41418-018-0160-1. Epub 2018 Jul 16. Erratum in: Cell Death Differ. 2019 Oct 22;:.


Traffic-related air pollution and eczema in the elderly: Findings from the SALIA cohort.

Schnass W, Hüls A, Vierkötter A, Krämer U, Krutmann J, Schikowski T.

Int J Hyg Environ Health. 2018 Jul;221(6):861-867. doi: 10.1016/j.ijheh.2018.06.002. Epub 2018 Jun 13.


Novel Means for Photoprotection.

Sondenheimer K, Krutmann J.

Front Med (Lausanne). 2018 May 29;5:162. doi: 10.3389/fmed.2018.00162. eCollection 2018. Review.


Commentary on the "Evidence- and Consensus-Based (S3) Guidelines for the Treatment of Actinic Keratosis" Published by the International League of Dermatological Societies in Cooperation with the European Dermatology Forum.

Diepgen TL, Kresken J, Krutmann J, Merk HF, Senger E, Surber C, Szeimies RM; GD Task Force "Licht.Hautkrebs.Prävention" of the Society for Dermopharmacy .

Skin Pharmacol Physiol. 2018;31(3):144-146. doi: 10.1159/000486687. Epub 2018 Apr 3.


Alternative test models for skin ageing research.

Nakamura M, Haarmann-Stemmann T, Krutmann J, Morita A.

Exp Dermatol. 2018 May;27(5):495-500. doi: 10.1111/exd.13519. Epub 2018 Apr 10.


A Time-Series Study of the Effect of Air Pollution on Outpatient Visits for Acne Vulgaris in Beijing.

Liu W, Pan X, Vierkötter A, Guo Q, Wang X, Wang Q, Seité S, Moyal D, Schikowski T, Krutmann J.

Skin Pharmacol Physiol. 2018;31(2):107-113. doi: 10.1159/000484482. Epub 2018 Feb 7.


Laser Scanning Microscopic Investigations of the Decontamination of Soot Nanoparticles from the Skin.

Lademann J, Knorr F, Patzelt A, Meinke MC, Richter H, Krutmann J, Rühl E, Doucet O.

Skin Pharmacol Physiol. 2018;31(2):87-94. doi: 10.1159/000485900. Epub 2018 Jan 20.


Indoor PM2.5 exposure affects skin aging manifestation in a Chinese population.

Ding A, Yang Y, Zhao Z, Hüls A, Vierkötter A, Yuan Z, Cai J, Zhang J, Gao W, Li J, Zhang M, Matsui M, Krutmann J, Kan H, Schikowski T, Jin L, Wang S.

Sci Rep. 2017 Nov 10;7(1):15329. doi: 10.1038/s41598-017-15295-8.


Comparative performance analysis of human iPSC-derived and primary neural progenitor cells (NPC) grown as neurospheres in vitro.

Hofrichter M, Nimtz L, Tigges J, Kabiri Y, Schröter F, Royer-Pokora B, Hildebrandt B, Schmuck M, Epanchintsev A, Theiss S, Adjaye J, Egly JM, Krutmann J, Fritsche E.

Stem Cell Res. 2017 Dec;25:72-82. doi: 10.1016/j.scr.2017.10.013. Epub 2017 Oct 26.


SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy.

Lang A, Anand R, Altinoluk-Hambüchen S, Ezzahoini H, Stefanski A, Iram A, Bergmann L, Urbach J, Böhler P, Hänsel J, Franke M, Stühler K, Krutmann J, Scheller J, Stork B, Reichert AS, Piekorz RP.

Aging (Albany NY). 2017 Oct 29;9(10):2163-2189. doi: 10.18632/aging.101307. Erratum in: Aging (Albany NY). 2018 Sep 28;10(9):2536c.


Diesel engine exhaust accelerates plaque formation in a mouse model of Alzheimer's disease.

Hullmann M, Albrecht C, van Berlo D, Gerlofs-Nijland ME, Wahle T, Boots AW, Krutmann J, Cassee FR, Bayer TA, Schins RPF.

Part Fibre Toxicol. 2017 Aug 30;14(1):35. doi: 10.1186/s12989-017-0213-5.


EPR Technology as Sensitive Method for Oxidative Stress Detection in Primary and Secondary Keratinocytes Induced by Two Selected Nanoparticles.

Lohan SB, Ahlberg S, Mensch A, Höppe D, Giulbudagian M, Calderón M, Grether-Beck S, Krutmann J, Lademann J, Meinke MC.

Cell Biochem Biophys. 2017 Dec;75(3-4):359-367. doi: 10.1007/s12013-017-0823-4. Epub 2017 Aug 28.


Effect of a Blueberry-Derived Antioxidant Matrix on Infrared-A Induced Gene Expression in Human Dermal Fibroblasts.

Grether-Beck S, Krutmann J, Wilkens K, D'Amato K.

J Drugs Dermatol. 2017 Aug 1;16(8):s125-s128.


Pollution and acne: is there a link?

Krutmann J, Moyal D, Liu W, Kandahari S, Lee GS, Nopadon N, Xiang LF, Seité S.

Clin Cosmet Investig Dermatol. 2017 May 19;10:199-204. doi: 10.2147/CCID.S131323. eCollection 2017. Review.


Age, gender and UV-exposition related effects on gene expression in in vivo aged short term cultivated human dermal fibroblasts.

Kaisers W, Boukamp P, Stark HJ, Schwender H, Tigges J, Krutmann J, Schaal H.

PLoS One. 2017 May 5;12(5):e0175657. doi: 10.1371/journal.pone.0175657. eCollection 2017.


[Sun protection].

Krutmann J, Stege H.

Hautarzt. 2017 May;68(5):348. doi: 10.1007/s00105-017-3981-9. German. No abstract available.


[New approaches for the prevention of actinic keratosis].

Stege H, Krutmann J.

Hautarzt. 2017 May;68(5):354-358. doi: 10.1007/s00105-017-3980-x. Review. German.


Genetic variants associated with skin aging in the Chinese Han population.

Gao W, Tan J, Hüls A, Ding A, Liu Y, Matsui MS, Vierkötter A, Krutmann J, Schikowski T, Jin L, Wang S.

J Dermatol Sci. 2017 Apr;86(1):21-29. doi: 10.1016/j.jdermsci.2016.12.017. Epub 2016 Dec 22.


A Genome-Wide Association Study of Basal Transepidermal Water Loss Finds that Variants at 9q34.3 Are Associated with Skin Barrier Function.

Zhang M, Li B, Wu S, Tan J, Yang Y, Marini A, Vierkötter A, Zhang J, Li H, Schikowski T, Jin L, Krutmann J, Wang S.

J Invest Dermatol. 2017 Apr;137(4):979-982. doi: 10.1016/j.jid.2016.11.030. Epub 2016 Dec 21. No abstract available.


Large-scale genome-wide scans do not support petaloid toenail as a Mendelian trait.

Zhang M, Wu S, Zhang J, Yang Y, Tan J, Guan H, Liu Y, Tang K, Krutmann J, Xu S, Jin L, Guan Y, Li H, Wang S.

J Genet Genomics. 2016 Dec 20;43(12):702-704. doi: 10.1016/j.jgg.2016.10.003. Epub 2016 Oct 14. No abstract available.


Reduction of neutrophilic lung inflammation by inhalation of the compatible solute ectoine: a randomized trial with elderly individuals.

Unfried K, Krämer U, Sydlik U, Autengruber A, Bilstein A, Stolz S, Marini A, Schikowski T, Keymel S, Krutmann J.

Int J Chron Obstruct Pulmon Dis. 2016 Oct 18;11:2573-2583. eCollection 2016.


Aryl Hydrocarbon Receptor in Keratinocytes Is Essential for Murine Skin Barrier Integrity.

Haas K, Weighardt H, Deenen R, Köhrer K, Clausen B, Zahner S, Boukamp P, Bloch W, Krutmann J, Esser C.

J Invest Dermatol. 2016 Nov;136(11):2260-2269. doi: 10.1016/j.jid.2016.06.627. Epub 2016 Jul 16.


The skin aging exposome.

Krutmann J, Bouloc A, Sore G, Bernard BA, Passeron T.

J Dermatol Sci. 2017 Mar;85(3):152-161. doi: 10.1016/j.jdermsci.2016.09.015. Epub 2016 Sep 28. Review.


Molecular evidence that oral supplementation with lycopene or lutein protects human skin against ultraviolet radiation: results from a double-blinded, placebo-controlled, crossover study.

Grether-Beck S, Marini A, Jaenicke T, Stahl W, Krutmann J.

Br J Dermatol. 2017 May;176(5):1231-1240. doi: 10.1111/bjd.15080. Epub 2017 Mar 15.


Genome-wide scans reveal variants at EDAR predominantly affecting hair straightness in Han Chinese and Uyghur populations.

Wu S, Tan J, Yang Y, Peng Q, Zhang M, Li J, Lu D, Liu Y, Lou H, Feng Q, Lu Y, Guan Y, Zhang Z, Jiao Y, Sabeti P, Krutmann J, Tang K, Jin L, Xu S, Wang S.

Hum Genet. 2016 Nov;135(11):1279-1286. Epub 2016 Aug 3.


Extrinsic skin ageing in German, Chinese and Japanese women manifests differently in all three groups depending on ethnic background, age and anatomical site.

Vierkötter A, Hüls A, Yamamoto A, Stolz S, Krämer U, Matsui MS, Morita A, Wang S, Li Z, Jin L, Krutmann J, Schikowski T.

J Dermatol Sci. 2016 Sep;83(3):219-25. doi: 10.1016/j.jdermsci.2016.05.011. Epub 2016 May 24.


MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4.

Lang A, Grether-Beck S, Singh M, Kuck F, Jakob S, Kefalas A, Altinoluk-Hambüchen S, Graffmann N, Schneider M, Lindecke A, Brenden H, Felsner I, Ezzahoini H, Marini A, Weinhold S, Vierkötter A, Tigges J, Schmidt S, Stühler K, Köhrer K, Uhrberg M, Haendeler J, Krutmann J, Piekorz RP.

Aging (Albany NY). 2016 Mar;8(3):484-505.


Recommendations for managing cutaneous disorders associated with advancing age.

Humbert P, Dréno B, Krutmann J, Luger TA, Triller R, Meaume S, Seité S.

Clin Interv Aging. 2016 Feb 12;11:141-8. doi: 10.2147/CIA.S96232. eCollection 2016. Review.


Traffic-Related Air Pollution Contributes to Development of Facial Lentigines: Further Epidemiological Evidence from Caucasians and Asians.

Hüls A, Vierkötter A, Gao W, Krämer U, Yang Y, Ding A, Stolz S, Matsui M, Kan H, Wang S, Jin L, Krutmann J, Schikowski T.

J Invest Dermatol. 2016 May;136(5):1053-1056. doi: 10.1016/j.jid.2015.12.045. Epub 2016 Feb 8. Review. No abstract available.


[Environmentally induced (extrinsic) skin aging].

Krutmann J, Schikowski T, Hüls A, Vierkötter A, Grether-Beck S.

Hautarzt. 2016 Feb;67(2):99-102. doi: 10.1007/s00105-015-3750-6. Review. German.


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