Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 119

1.

Ultramorphological analysis of plaque advancement and cholesterol crystal formation in Ldlr knockout mouse atherosclerosis.

Baumer Y, McCurdy S, Jin X, Weatherby TM, Dey AK, Mehta NN, Yap JK, Kruth HS, Boisvert WA.

Atherosclerosis. 2019 Jun 12;287:100-111. doi: 10.1016/j.atherosclerosis.2019.05.029. [Epub ahead of print]

PMID:
31247346
2.

Modified LDL Particles Activate Inflammatory Pathways in Monocyte-derived Macrophages: Transcriptome Analysis.

Orekhov AN, Oishi Y, Nikiforov NG, Zhelankin AV, Dubrovsky L, Sobenin IA, Kel A, Stelmashenko D, Makeev VJ, Foxx K, Jin X, Kruth HS, Bukrinsky M.

Curr Pharm Des. 2018;24(26):3143-3151. doi: 10.2174/1381612824666180911120039.

3.

HDL activates expression of genes stimulating cholesterol efflux in human monocyte-derived macrophages.

Orekhov AN, Pushkarsky T, Oishi Y, Nikiforov NG, Zhelankin AV, Dubrovsky L, Makeev VJ, Foxx K, Jin X, Kruth HS, Sobenin IA, Sukhorukov VN, Zakiev ER, Kontush A, Le Goff W, Bukrinsky M.

Exp Mol Pathol. 2018 Oct;105(2):202-207. doi: 10.1016/j.yexmp.2018.08.003. Epub 2018 Aug 16.

PMID:
30118702
4.

A Mouse Model of Schnyder Corneal Dystrophy with the N100S Point Mutation.

Dong F, Jin X, Boettler MA, Sciulli H, Abu-Asab M, Del Greco C, Wang S, Hu YC, Campos MM, Jackson SN, Muller L, Woods AS, Combs CA, Zhang J, Nickerson ML, Kruth HS, Weiss JS, Kao WW.

Sci Rep. 2018 Jul 5;8(1):10219. doi: 10.1038/s41598-018-28545-0.

5.

Two polymorphic cholesterol monohydrate crystal structures form in macrophage culture models of atherosclerosis.

Varsano N, Beghi F, Elad N, Pereiro E, Dadosh T, Pinkas I, Perez-Berna AJ, Jin X, Kruth HS, Leiserowitz L, Addadi L.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7662-7669. doi: 10.1073/pnas.1803119115. Epub 2018 Jul 2.

6.

Macrophages Shed Excess Cholesterol in Unique Extracellular Structures Containing Cholesterol Microdomains.

Jin X, Dimitriadis EK, Liu Y, Combs CA, Chang J, Varsano N, Stempinski E, Flores R, Jackson SN, Muller L, Woods AS, Addadi L, Kruth HS.

Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1504-1518. doi: 10.1161/ATVBAHA.118.311269. Epub 2018 May 31.

7.

Chronic skin inflammation accelerates macrophage cholesterol crystal formation and atherosclerosis.

Baumer Y, Ng Q, Sanda GE, Dey AK, Teague HL, Sorokin AV, Dagur PK, Silverman JI, Harrington CL, Rodante JA, Rose SM, Varghese NJ, Belur AD, Goyal A, Gelfand JM, Springer DA, Bleck CK, Thomas CL, Yu ZX, Winge MC, Kruth HS, Marinkovich MP, Joshi AA, Playford MP, Mehta NN.

JCI Insight. 2018 Jan 11;3(1). pii: 97179. doi: 10.1172/jci.insight.97179. eCollection 2018 Jan 11.

8.

Measurement of Aortic Cell Fluid-Phase Pinocytosis in vivo by Flow Cytometry.

Anzinger JJ, Jin X, Palmer CS, Dagur P, Barthwal MK, Kruth HS.

J Vasc Res. 2017;54(4):195-199. doi: 10.1159/000475934. Epub 2017 Jun 16.

9.

Use of Primary Macrophages for Searching Novel Immunocorrectors.

Nikiforov NG, Elizova NV, Bukrinsky M, Dubrovsky L, Makeev VJ, Wakabayashi Y, Liu P, Foxx KK, Kruth HS, Jin X, Zakiev ER, Orekhov AN.

Curr Pharm Des. 2017;23(6):915-920. doi: 10.2174/1381612823666170125110128. Review.

10.

Development of Correlative Cryo-soft X-ray Tomography and Stochastic Reconstruction Microscopy. A Study of Cholesterol Crystal Early Formation in Cells.

Varsano N, Dadosh T, Kapishnikov S, Pereiro E, Shimoni E, Jin X, Kruth HS, Leiserowitz L, Addadi L.

J Am Chem Soc. 2016 Nov 16;138(45):14931-14940. Epub 2016 Nov 8.

11.

ABCA1 (ATP-Binding Cassette Transporter A1) Mediates ApoA-I (Apolipoprotein A-I) and ApoA-I Mimetic Peptide Mobilization of Extracellular Cholesterol Microdomains Deposited by Macrophages.

Jin X, Sviridov D, Liu Y, Vaisman B, Addadi L, Remaley AT, Kruth HS.

Arterioscler Thromb Vasc Biol. 2016 Dec;36(12):2283-2291. Epub 2016 Oct 6.

12.
13.

ABCA1 contributes to macrophage deposition of extracellular cholesterol.

Jin X, Freeman SR, Vaisman B, Liu Y, Chang J, Varsano N, Addadi L, Remaley A, Kruth HS.

J Lipid Res. 2015 Sep;56(9):1720-6. doi: 10.1194/jlr.M060053. Epub 2015 Jul 22.

14.

Increased plasma cholesterol esterification by LCAT reduces diet-induced atherosclerosis in SR-BI knockout mice.

Thacker SG, Rousset X, Esmail S, Zarzour A, Jin X, Collins HL, Sampson M, Stonik J, Demosky S, Malide DA, Freeman L, Vaisman BL, Kruth HS, Adelman SJ, Remaley AT.

J Lipid Res. 2015 Jul;56(7):1282-95. doi: 10.1194/jlr.M048629. Epub 2015 May 11.

15.

Endotoxin contamination of apolipoprotein A-I: effect on macrophage proliferation--a cautionary tale.

Jin X, Xu Q, Champion K, Kruth HS.

Atherosclerosis. 2015 May;240(1):121-4. doi: 10.1016/j.atherosclerosis.2015.03.007. Epub 2015 Mar 9.

16.

ABCG1-mediated generation of extracellular cholesterol microdomains.

Freeman SR, Jin X, Anzinger JJ, Xu Q, Purushothaman S, Fessler MB, Addadi L, Kruth HS.

J Lipid Res. 2014 Jan;55(1):115-27. doi: 10.1194/jlr.M044552. Epub 2013 Nov 8.

17.

The TERE1 protein interacts with mitochondrial TBL2: regulation of trans-membrane potential, ROS/RNS and SXR target genes.

Fredericks WJ, McGarvey T, Wang H, Zheng Y, Fredericks NJ, Yin H, Wang LP, Hsiao W, Lee R, Weiss JS, Nickerson ML, Kruth HS, Rauscher FJ 3rd, Malkowicz SB.

J Cell Biochem. 2013 Sep;114(9):2170-87. doi: 10.1002/jcb.24567.

PMID:
23564352
18.

Fluid-phase pinocytosis of native low density lipoprotein promotes murine M-CSF differentiated macrophage foam cell formation.

Barthwal MK, Anzinger JJ, Xu Q, Bohnacker T, Wymann MP, Kruth HS.

PLoS One. 2013;8(3):e58054. doi: 10.1371/journal.pone.0058054. Epub 2013 Mar 11.

20.

The UBIAD1 prenyltransferase links menaquinone-4 [corrected] synthesis to cholesterol metabolic enzymes.

Nickerson ML, Bosley AD, Weiss JS, Kostiha BN, Hirota Y, Brandt W, Esposito D, Kinoshita S, Wessjohann L, Morham SG, Andresson T, Kruth HS, Okano T, Dean M.

Hum Mutat. 2013 Feb;34(2):317-29. doi: 10.1002/humu.22230. Epub 2012 Nov 27. Erratum in: Hum Mutat. 2013 Jul;34(7):1046.

21.

Passage of low-density lipoproteins through Bruch's membrane and choroid.

Cankova Z, Huang JD, Kruth HS, Johnson M.

Exp Eye Res. 2011 Dec;93(6):947-55. doi: 10.1016/j.exer.2011.10.016. Epub 2011 Nov 3.

22.

Murine bone marrow-derived macrophages differentiated with GM-CSF become foam cells by PI3Kγ-dependent fluid-phase pinocytosis of native LDL.

Anzinger JJ, Chang J, Xu Q, Barthwal MK, Bohnacker T, Wymann MP, Kruth HS.

J Lipid Res. 2012 Jan;53(1):34-42. doi: 10.1194/jlr.M018887. Epub 2011 Nov 4.

23.
24.

Phospholipase A2 mediates apolipoprotein-independent uptake of chylomicron remnant-like particles by human macrophages.

Napolitano M, Kruth HS, Bravo E.

Int J Vasc Med. 2012;2012:501954. doi: 10.1155/2012/501954. Epub 2011 Aug 21.

25.

Triglycidyl amine crosslinking combined with ethanol inhibits bioprosthetic heart valve calcification.

Connolly JM, Bakay MA, Alferiev IS, Gorman RC, Gorman JH 3rd, Kruth HS, Ashworth PE, Kutty JK, Schoen FJ, Bianco RW, Levy RJ.

Ann Thorac Surg. 2011 Sep;92(3):858-65. doi: 10.1016/j.athoracsur.2011.04.104.

26.

The bladder tumor suppressor protein TERE1 (UBIAD1) modulates cell cholesterol: implications for tumor progression.

Fredericks WJ, McGarvey T, Wang H, Lal P, Puthiyaveettil R, Tomaszewski J, Sepulveda J, Labelle E, Weiss JS, Nickerson ML, Kruth HS, Brandt W, Wessjohann LA, Malkowicz SB.

DNA Cell Biol. 2011 Nov;30(11):851-64. doi: 10.1089/dna.2011.1315. Epub 2011 Jul 8.

27.

Evaluation of transduction efficiency in macrophage colony-stimulating factor differentiated human macrophages using HIV-1 based lentiviral vectors.

Leyva FJ, Anzinger JJ, McCoy JP Jr, Kruth HS.

BMC Biotechnol. 2011 Jan 31;11:13. doi: 10.1186/1472-6750-11-13.

28.

Native low-density lipoprotein uptake by macrophage colony-stimulating factor-differentiated human macrophages is mediated by macropinocytosis and micropinocytosis.

Anzinger JJ, Chang J, Xu Q, Buono C, Li Y, Leyva FJ, Park BC, Greene LE, Kruth HS.

Arterioscler Thromb Vasc Biol. 2010 Oct;30(10):2022-31. doi: 10.1161/ATVBAHA.110.210849. Epub 2010 Jul 15.

29.

UBIAD1 mutation alters a mitochondrial prenyltransferase to cause Schnyder corneal dystrophy.

Nickerson ML, Kostiha BN, Brandt W, Fredericks W, Xu KP, Yu FS, Gold B, Chodosh J, Goldberg M, Lu DW, Yamada M, Tervo TM, Grutzmacher R, Croasdale C, Hoeltzenbein M, Sutphin J, Malkowicz SB, Wessjohann L, Kruth HS, Dean M, Weiss JS.

PLoS One. 2010 May 21;5(5):e10760. doi: 10.1371/journal.pone.0010760.

30.

Extracellular cholesterol-rich microdomains generated by human macrophages and their potential function in reverse cholesterol transport.

Ong DS, Anzinger JJ, Leyva FJ, Rubin N, Addadi L, Kruth HS.

J Lipid Res. 2010 Aug;51(8):2303-13. doi: 10.1194/jlr.M005660. Epub 2010 Apr 26.

31.

Fluorescent pegylated nanoparticles demonstrate fluid-phase pinocytosis by macrophages in mouse atherosclerotic lesions.

Buono C, Anzinger JJ, Amar M, Kruth HS.

J Clin Invest. 2009 May;119(5):1373-81. doi: 10.1172/JCI35548. Epub 2009 Apr 13.

32.

Heterogeneity of human macrophages in culture and in atherosclerotic plaques.

Waldo SW, Li Y, Buono C, Zhao B, Billings EM, Chang J, Kruth HS.

Am J Pathol. 2008 Apr;172(4):1112-26. doi: 10.2353/ajpath.2008.070513. Epub 2008 Mar 5.

33.

Genetic analysis of 14 families with Schnyder crystalline corneal dystrophy reveals clues to UBIAD1 protein function.

Weiss JS, Kruth HS, Kuivaniemi H, Tromp G, Karkera J, Mahurkar S, Lisch W, Dupps WJ Jr, White PS, Winters RS, Kim C, Rapuano CJ, Sutphin J, Reidy J, Hu FR, Lu DW, Ebenezer N, Nickerson ML.

Am J Med Genet A. 2008 Feb 1;146A(3):271-83. doi: 10.1002/ajmg.a.32201.

PMID:
18176953
34.

Mutations in the UBIAD1 gene on chromosome short arm 1, region 36, cause Schnyder crystalline corneal dystrophy.

Weiss JS, Kruth HS, Kuivaniemi H, Tromp G, White PS, Winters RS, Lisch W, Henn W, Denninger E, Krause M, Wasson P, Ebenezer N, Mahurkar S, Nickerson ML.

Invest Ophthalmol Vis Sci. 2007 Nov;48(11):5007-12.

PMID:
17962451
35.

Liver X receptors inhibit human monocyte-derived macrophage foam cell formation by inhibiting fluid-phase pinocytosis of LDL.

Buono C, Li Y, Waldo SW, Kruth HS.

J Lipid Res. 2007 Nov;48(11):2411-8. Epub 2007 Aug 10.

36.

Protein kinase C beta and delta isoenzymes mediate cholesterol accumulation in PMA-activated macrophages.

Ma HT, Lin WW, Zhao B, Wu WT, Huang W, Li Y, Jones NL, Kruth HS.

Biochem Biophys Res Commun. 2006 Oct 13;349(1):214-20. Epub 2006 Aug 11.

PMID:
16930534
37.
38.

Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy.

Curcio CA, Presley JB, Malek G, Medeiros NE, Avery DV, Kruth HS.

Exp Eye Res. 2005 Dec;81(6):731-41. Epub 2005 Jul 11.

PMID:
16005869
39.

Lipoprotein-like particles and cholesteryl esters in human Bruch's membrane: initial characterization.

Li CM, Chung BH, Presley JB, Malek G, Zhang X, Dashti N, Li L, Chen J, Bradley K, Kruth HS, Curcio CA.

Invest Ophthalmol Vis Sci. 2005 Jul;46(7):2576-86.

PMID:
15980251
40.

Macropinocytosis is the endocytic pathway that mediates macrophage foam cell formation with native low density lipoprotein.

Kruth HS, Jones NL, Huang W, Zhao B, Ishii I, Chang J, Combs CA, Malide D, Zhang WY.

J Biol Chem. 2005 Jan 21;280(3):2352-60. Epub 2004 Nov 8.

41.

Retention of aggregated LDL by cultured human coronary artery endothelial cells.

Zhao B, Huang W, Zhang WY, Ishii I, Kruth HS.

Biochem Biophys Res Commun. 2004 Aug 27;321(3):728-35.

PMID:
15358167
42.

Accumulation of cholesterol in the lesions of focal segmental glomerulosclerosis.

Lee HS, Kruth HS.

Nephrology (Carlton). 2003 Oct;8(5):224-3.

PMID:
15012708
43.

Intraplaque hemorrhage and progression of coronary atheroma.

Kolodgie FD, Gold HK, Burke AP, Fowler DR, Kruth HS, Weber DK, Farb A, Guerrero LJ, Hayase M, Kutys R, Narula J, Finn AV, Virmani R.

N Engl J Med. 2003 Dec 11;349(24):2316-25.

44.

Histopathology and regression of retinal hard exudates in diabetic retinopathy after reduction of elevated serum lipid levels.

Cusick M, Chew EY, Chan CC, Kruth HS, Murphy RP, Ferris FL 3rd.

Ophthalmology. 2003 Nov;110(11):2126-33.

PMID:
14597519
45.

Structural information about organized cholesterol domains from specific antibody recognition.

Addadi L, Geva M, Kruth HS.

Biochim Biophys Acta. 2003 Mar 10;1610(2):208-16. Review.

46.

Sequestration of aggregated low-density lipoproteins by macrophages.

Kruth HS.

Curr Opin Lipidol. 2002 Oct;13(5):483-8. Review.

PMID:
12352011
47.

PMA activation of macrophages alters macrophage metabolism of aggregated LDL.

Huang W, Ishii I, Zhang WY, Sonobe M, Kruth HS.

J Lipid Res. 2002 Aug;43(8):1275-82.

48.

Macrophage foam cell formation with native low density lipoprotein.

Kruth HS, Huang W, Ishii I, Zhang WY.

J Biol Chem. 2002 Sep 13;277(37):34573-80. Epub 2002 Jul 12.

49.

Lipoprotein cholesterol and atherosclerosis.

Kruth HS.

Curr Mol Med. 2001 Dec;1(6):633-53. Review.

PMID:
11899253
50.

Monoclonal antibody detection of plasma membrane cholesterol microdomains responsive to cholesterol trafficking.

Kruth HS, Ifrim I, Chang J, Addadi L, Perl-Treves D, Zhang WY.

J Lipid Res. 2001 Sep;42(9):1492-500.

Supplemental Content

Loading ...
Support Center