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Items: 13

1.

Identification of a Clinically Relevant Signature for Early Progression in KRAS-Driven Lung Adenocarcinoma.

Neidler S, Kruspig B, Hewit K, Monteverde T, Gyuraszova K, Braun A, Clark W, James D, Hedley A, Nieswandt B, Shanks E, Dick C, Murphy DJ.

Cancers (Basel). 2019 Apr 29;11(5). pii: E600. doi: 10.3390/cancers11050600.

2.

A Neuronal Relay Mediates a Nutrient Responsive Gut/Fat Body Axis Regulating Energy Homeostasis in Adult Drosophila.

Scopelliti A, Bauer C, Yu Y, Zhang T, Kruspig B, Murphy DJ, Vidal M, Maddocks ODK, Cordero JB.

Cell Metab. 2019 Feb 5;29(2):269-284.e10. doi: 10.1016/j.cmet.2018.09.021. Epub 2018 Oct 18.

3.

The ERBB network facilitates KRAS-driven lung tumorigenesis.

Kruspig B, Monteverde T, Neidler S, Hock A, Kerr E, Nixon C, Clark W, Hedley A, Laing S, Coffelt SB, Le Quesne J, Dick C, Vousden KH, Martins CP, Murphy DJ.

Sci Transl Med. 2018 Jun 20;10(446). pii: eaao2565. doi: 10.1126/scitranslmed.aao2565. Erratum in: Sci Transl Med. 2018 Nov 21;10(468):.

PMID:
29925636
4.

Author Correction: CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity.

Walton JB, Farquharson M, Mason S, Port J, Kruspig B, Dowson S, Stevenson D, Murphy D, Matzuk M, Kim J, Coffelt S, Blyth K, McNeish IA.

Sci Rep. 2018 Apr 13;8(1):6231. doi: 10.1038/s41598-018-24099-3.

5.

Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress.

Port J, Muthalagu N, Raja M, Ceteci F, Monteverde T, Kruspig B, Hedley A, Kalna G, Lilla S, Neilson L, Brucoli M, Gyuraszova K, Tait-Mulder J, Mezna M, Svambaryte S, Bryson A, Sumpton D, McVie A, Nixon C, Drysdale M, Esumi H, Murray GI, Sansom OJ, Zanivan SR, Murphy DJ.

Cancer Discov. 2018 May;8(5):632-647. doi: 10.1158/2159-8290.CD-17-0533. Epub 2018 Mar 2.

6.

CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity.

Walton JB, Farquharson M, Mason S, Port J, Kruspig B, Dowson S, Stevenson D, Murphy D, Matzuk M, Kim J, Coffelt S, Blyth K, McNeish IA.

Sci Rep. 2017 Dec 4;7(1):16827. doi: 10.1038/s41598-017-17119-1. Erratum in: Sci Rep. 2018 Apr 13;8(1):6231.

7.

Contrasting effects of glutamine deprivation on apoptosis induced by conventionally used anticancer drugs.

Valter K, Chen L, Kruspig B, Maximchik P, Cui H, Zhivotovsky B, Gogvadze V.

Biochim Biophys Acta Mol Cell Res. 2017 Mar;1864(3):498-506. doi: 10.1016/j.bbamcr.2016.12.016. Epub 2016 Dec 18.

8.

Targeting succinate:ubiquinone reductase potentiates the efficacy of anticancer therapy.

Kruspig B, Valter K, Skender B, Zhivotovsky B, Gogvadze V.

Biochim Biophys Acta. 2016 Aug;1863(8):2065-71. doi: 10.1016/j.bbamcr.2016.04.026. Epub 2016 Apr 29.

9.

Mitochondrial substrates in cancer: drivers or passengers?

Kruspig B, Zhivotovsky B, Gogvadze V.

Mitochondrion. 2014 Nov;19 Pt A:8-19. doi: 10.1016/j.mito.2014.08.007. Epub 2014 Aug 30. Review.

PMID:
25179741
10.

Citrate kills tumor cells through activation of apical caspases.

Kruspig B, Nilchian A, Orrenius S, Zhivotovsky B, Gogvadze V.

Cell Mol Life Sci. 2012 Dec;69(24):4229-37. doi: 10.1007/s00018-012-1166-3. Epub 2012 Oct 10.

PMID:
23052210
11.

Contrasting effects of α-tocopheryl succinate on cisplatin- and etoposide-induced apoptosis.

Kruspig B, Zhivotovsky B, Gogvadze V.

Mitochondrion. 2013 Sep;13(5):533-8. doi: 10.1016/j.mito.2012.08.001. Epub 2012 Aug 18.

PMID:
22971517
12.

Targeting mitochondria by α-tocopheryl succinate kills neuroblastoma cells irrespective of MycN oncogene expression.

Kruspig B, Nilchian A, Bejarano I, Orrenius S, Zhivotovsky B, Gogvadze V.

Cell Mol Life Sci. 2012 Jun;69(12):2091-9. doi: 10.1007/s00018-012-0918-4.

PMID:
22286068
13.

Autocrine prostaglandin E2 signaling promotes tumor cell survival and proliferation in childhood neuroblastoma.

Rasmuson A, Kock A, Fuskevåg OM, Kruspig B, Simón-Santamaría J, Gogvadze V, Johnsen JI, Kogner P, Sveinbjörnsson B.

PLoS One. 2012;7(1):e29331. doi: 10.1371/journal.pone.0029331. Epub 2012 Jan 19.

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