Sort by
Items per page

Send to

Choose Destination

Search results

Items: 17


Optimization of Ligands Using Focused DNA-Encoded Libraries To Develop a Selective, Cell-Permeable CBX8 Chromodomain Inhibitor.

Wang S, Denton KE, Hobbs KF, Weaver T, McFarlane JMB, Connelly KE, Gignac MC, Milosevich N, Hof F, Paci I, Musselman CA, Dykhuizen EC, Krusemark CJ.

ACS Chem Biol. 2020 Jan 17;15(1):112-131. doi: 10.1021/acschembio.9b00654. Epub 2019 Dec 12.


Selection of DNA-Encoded Libraries to Protein Targets within and on Living Cells.

Cai B, Kim D, Akhand S, Sun Y, Cassell RJ, Alpsoy A, Dykhuizen EC, Van Rijn RM, Wendt MK, Krusemark CJ.

J Am Chem Soc. 2019 Oct 30;141(43):17057-17061. doi: 10.1021/jacs.9b08085. Epub 2019 Oct 22.


Application of a Substrate-Mediated Selection with c-Src Tyrosine Kinase to a DNA-Encoded Chemical Library.

Kim D, Sun Y, Xie D, Denton KE, Chen H, Lin H, Wendt MK, Post CB, Krusemark CJ.

Molecules. 2019 Jul 30;24(15). pii: E2764. doi: 10.3390/molecules24152764.


Spleen Tyrosine Kinase-Mediated Autophagy Is Required for Epithelial-Mesenchymal Plasticity and Metastasis in Breast Cancer.

Shinde A, Hardy SD, Kim D, Akhand SS, Jolly MK, Wang WH, Anderson JC, Khodadadi RB, Brown WS, George JT, Liu S, Wan J, Levine H, Willey CD, Krusemark CJ, Geahlen RL, Wendt MK.

Cancer Res. 2019 Apr 15;79(8):1831-1843. doi: 10.1158/0008-5472.CAN-18-2636. Epub 2019 Feb 7.


Robustness of In Vitro Selection Assays of DNA-Encoded Peptidomimetic Ligands to CBX7 and CBX8.

Denton KE, Wang S, Gignac MC, Milosevich N, Hof F, Dykhuizen EC, Krusemark CJ.

SLAS Discov. 2018 Jun;23(5):417-428. doi: 10.1177/2472555217750871. Epub 2018 Jan 8.


Crosslinking of DNA-linked ligands to target proteins for enrichment from DNA-encoded libraries.

Denton KE, Krusemark CJ.

Medchemcomm. 2016 Oct 1;7(10):2020-2027. doi: 10.1039/C6MD00288A. Epub 2016 Aug 2.


A DNA-assisted immunoassay for enzyme activity via a DNA-linked, activity-based probe.

Kim D, Jetson RR, Krusemark CJ.

Chem Commun (Camb). 2017 Aug 22;53(68):9474-9477. doi: 10.1039/c7cc05236g.


Directed Chemical Evolution with an Outsized Genetic Code.

Krusemark CJ, Tilmans NP, Brown PO, Harbury PB.

PLoS One. 2016 Aug 10;11(8):e0154765. doi: 10.1371/journal.pone.0154765. eCollection 2016.


Sensing Enzymatic Activity by Exposure and Selection of DNA-Encoded Probes.

Jetson RR, Krusemark CJ.

Angew Chem Int Ed Engl. 2016 Aug 8;55(33):9562-6. doi: 10.1002/anie.201603387. Epub 2016 Jun 29.


Chemical derivatization of peptide carboxyl groups for highly efficient electron transfer dissociation.

Frey BL, Ladror DT, Sondalle SB, Krusemark CJ, Jue AL, Coon JJ, Smith LM.

J Am Soc Mass Spectrom. 2013 Nov;24(11):1710-21. doi: 10.1007/s13361-013-0701-2. Epub 2013 Aug 6.


Complete chemical modification of amine and acid functional groups of peptides and small proteins.

Krusemark CJ, Frey BL, Smith LM, Belshaw PJ.

Methods Mol Biol. 2011;753:77-91. doi: 10.1007/978-1-61779-148-2_6.


Expedient synthesis of a modular phosphate affinity reagent.

Tilmans NP, Krusemark CJ, Harbury PA.

Bioconjug Chem. 2010 Jun 16;21(6):1010-3. doi: 10.1021/bc900538b.


Ion-Ion Reactions with Fixed-Charge Modified Proteins to Produce Ions in a Single, Very High Charge State.

Frey BL, Krusemark CJ, Ledvina AR, Coon JJ, Belshaw PJ, Smith LM.

Int J Mass Spectrom. 2008 Oct 1;276(2-3):136-143.


Modifying the charge state distribution of proteins in electrospray ionization mass spectrometry by chemical derivatization.

Krusemark CJ, Frey BL, Belshaw PJ, Smith LM.

J Am Soc Mass Spectrom. 2009 Sep;20(9):1617-25. doi: 10.1016/j.jasms.2009.04.017. Epub 2009 May 4.


Global amine and acid functional group modification of proteins.

Krusemark CJ, Ferguson JT, Wenger CD, Kelleher NL, Belshaw PJ.

Anal Chem. 2008 Feb 1;80(3):713-20. doi: 10.1021/ac7019317. Epub 2008 Jan 10.


Covalent labelling of fusion proteins in live cells via an engineered receptor-ligand pair.

Krusemark CJ, Belshaw PJ.

Org Biomol Chem. 2007 Jul 21;5(14):2201-4. Epub 2007 Jun 13.


Mixed isotope photoaffinity reagents for identification of small-molecule targets by mass spectrometry.

Lamos SM, Krusemark CJ, McGee CJ, Scalf M, Smith LM, Belshaw PJ.

Angew Chem Int Ed Engl. 2006 Jun 26;45(26):4329-33. No abstract available.


Supplemental Content

Loading ...
Support Center