Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 70

1.

Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein.

Spadaro M, Winklmeier S, Beltrán E, Macrini C, Höftberger R, Schuh E, Thaler FS, Gerdes LA, Laurent S, Gerhards R, Brändle S, Dornmair K, Breithaupt C, Krumbholz M, Moser M, Krishnamoorthy G, Kamp F, Jenne D, Hohlfeld R, Kümpfel T, Lassmann H, Kawakami N, Meinl E.

Ann Neurol. 2018 Aug;84(2):315-328. doi: 10.1002/ana.25291. Epub 2018 Sep 9.

PMID:
30014603
2.

Front-line imatinib treatment in children and adolescents with chronic myeloid leukemia: results from a phase III trial.

Suttorp M, Schulze P, Glauche I, Göhring G, von Neuhoff N, Metzler M, Sedlacek P, de Bont ESJM, Balduzzi A, Lausen B, Aleinikova O, Sufliarska S, Henze G, Strauss G, Eggert A, Kremens B, Groll AH, Berthold F, Klein C, Groß-Wieltsch U, Sykora KW, Borkhardt A, Kulozik AE, Schrappe M, Nowasz C, Krumbholz M, Tauer JT, Claviez A, Harbott J, Kreipe HH, Schlegelberger B, Thiede C.

Leukemia. 2018 Jul;32(7):1657-1669. doi: 10.1038/s41375-018-0179-9. Epub 2018 Jun 20.

PMID:
29925908
3.

Characterization and diagnostic application of genomic NPM-ALK fusion sequences in anaplastic large-cell lymphoma.

Krumbholz M, Woessmann W, Zierk J, Seniuk D, Ceppi P, Zimmermann M, Singh VK, Metzler M, Damm-Welk C.

Oncotarget. 2018 May 29;9(41):26543-26555. doi: 10.18632/oncotarget.25489. eCollection 2018 May 29.

4.

Nerve Ultrasound Predicts Treatment Response in Chronic Inflammatory Demyelinating Polyradiculoneuropathy-a Prospective Follow-Up.

Härtig F, Ross M, Dammeier NM, Fedtke N, Heiling B, Axer H, Décard BF, Auffenberg E, Koch M, Rattay TW, Krumbholz M, Bornemann A, Lerche H, Winter N, Grimm A.

Neurotherapeutics. 2018 Apr;15(2):439-451. doi: 10.1007/s13311-018-0609-4.

PMID:
29435815
5.

Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response.

Stellmann JP, Krumbholz M, Friede T, Gahlen A, Borisow N, Fischer K, Hellwig K, Pache F, Ruprecht K, Havla J, Kümpfel T, Aktas O, Hartung HP, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Young KL, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker RA, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Zettl U, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C, Kleiter I; NEMOS (Neuromyelitis Optica Study Group).

J Neurol Neurosurg Psychiatry. 2017 Aug;88(8):639-647. doi: 10.1136/jnnp-2017-315603. Epub 2017 Jun 1.

6.

Influence of female sex and fertile age on neuromyelitis optica spectrum disorders.

Borisow N, Kleiter I, Gahlen A, Fischer K, Wernecke KD, Pache F, Ruprecht K, Havla J, Krumbholz M, Kümpfel T, Aktas O, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Weissert R, Stellmann JP, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker RA, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Winkelmann A, Marouf W, Rückriem L, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C, Hellwig K; NEMOS (Neuromyelitis Optica Study Group).

Mult Scler. 2017 Jul;23(8):1092-1103. doi: 10.1177/1352458516671203. Epub 2016 Oct 6.

PMID:
27758954
7.

Autoantibodies to MOG in a distinct subgroup of adult multiple sclerosis.

Spadaro M, Gerdes LA, Krumbholz M, Ertl-Wagner B, Thaler FS, Schuh E, Metz I, Blaschek A, Dick A, Brück W, Hohlfeld R, Meinl E, Kümpfel T.

Neurol Neuroimmunol Neuroinflamm. 2016 Jun 30;3(5):e257. doi: 10.1212/NXI.0000000000000257. eCollection 2016 Oct.

8.

Features of Human CD3+CD20+ T Cells.

Schuh E, Berer K, Mulazzani M, Feil K, Meinl I, Lahm H, Krane M, Lange R, Pfannes K, Subklewe M, Gürkov R, Bradl M, Hohlfeld R, Kümpfel T, Meinl E, Krumbholz M.

J Immunol. 2016 Aug 15;197(4):1111-7. doi: 10.4049/jimmunol.1600089. Epub 2016 Jul 13.

9.

Genomic EWSR1 Fusion Sequence as Highly Sensitive and Dynamic Plasma Tumor Marker in Ewing Sarcoma.

Krumbholz M, Hellberg J, Steif B, Bäuerle T, Gillmann C, Fritscher T, Agaimy A, Frey B, Juengert J, Wardelmann E, Hartmann W, Juergens H, Dirksen U, Metzler M.

Clin Cancer Res. 2016 Sep 1;22(17):4356-65. doi: 10.1158/1078-0432.CCR-15-3028. Epub 2016 Jun 9. Erratum in: Clin Cancer Res. 2017 Jan 15;23 (2):610.

10.

Efficacy of glatiramer acetate in neuromyelitis optica spectrum disorder: a multicenter retrospective study.

Ayzenberg I, Schöllhammer J, Hoepner R, Hellwig K, Ringelstein M, Aktas O, Kümpfel T, Krumbholz M, Trebst C, Paul F, Pache F, Obermann M, Zeltner L, Schwab M, Berthele A, Jarius S, Kleiter I; Neuromyelitis Optica Study Group.

J Neurol. 2016 Mar;263(3):575-82. doi: 10.1007/s00415-015-7991-1. Epub 2016 Jan 25.

PMID:
26810718
11.

Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid.

Wuhrer M, Selman MH, McDonnell LA, Kümpfel T, Derfuss T, Khademi M, Olsson T, Hohlfeld R, Meinl E, Krumbholz M.

J Neuroinflammation. 2015 Dec 18;12:235. doi: 10.1186/s12974-015-0450-1.

12.

Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses.

Kleiter I, Gahlen A, Borisow N, Fischer K, Wernecke KD, Wegner B, Hellwig K, Pache F, Ruprecht K, Havla J, Krumbholz M, Kümpfel T, Aktas O, Hartung HP, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Stellmann JP, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker R, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Winkelmann A, Marouf W, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C; Neuromyelitis Optica Study Group.

Ann Neurol. 2016 Feb;79(2):206-16. doi: 10.1002/ana.24554. Epub 2015 Nov 26.

PMID:
26537743
13.

Fingolimod induces neuroprotective factors in human astrocytes.

Hoffmann FS, Hofereiter J, Rübsamen H, Melms J, Schwarz S, Faber H, Weber P, Pütz B, Loleit V, Weber F, Hohlfeld R, Meinl E, Krumbholz M.

J Neuroinflammation. 2015 Sep 30;12:184. doi: 10.1186/s12974-015-0393-6.

14.

From initiation to eradication: the lifespan of an MLL-rearranged therapy-related paediatric AML.

Krumbholz M, Bradtke J, Stachel D, Peters O, Hero B, Holter W, Slany R, Metzler M.

Bone Marrow Transplant. 2015 Oct;50(10):1382-4. doi: 10.1038/bmt.2015.155. Epub 2015 Jul 6. No abstract available.

PMID:
26146805
15.

γ-Secretase directly sheds the survival receptor BCMA from plasma cells.

Laurent SA, Hoffmann FS, Kuhn PH, Cheng Q, Chu Y, Schmidt-Supprian M, Hauck SM, Schuh E, Krumbholz M, Rübsamen H, Wanngren J, Khademi M, Olsson T, Alexander T, Hiepe F, Pfister HW, Weber F, Jenne D, Wekerle H, Hohlfeld R, Lichtenthaler SF, Meinl E.

Nat Commun. 2015 Jun 11;6:7333. doi: 10.1038/ncomms8333.

16.

Expanding spectrum of neurologic manifestations in patients with NLRP3 low-penetrance mutations.

Schuh E, Lohse P, Ertl-Wagner B, Witt M, Krumbholz M, Frankenberger M, Gerdes LA, Hohlfeld R, Kümpfel T.

Neurol Neuroimmunol Neuroinflamm. 2015 May 14;2(4):e109. doi: 10.1212/NXI.0000000000000109. eCollection 2015 Aug.

17.

Very late-onset neuromyelitis optica spectrum disorder beyond the age of 75.

Krumbholz M, Hofstadt-van Oy U, Angstwurm K, Kleiter I, Jarius S, Paul F, Aktas O, Buchholz G, Kern P, Straube A, Kümpfel T.

J Neurol. 2015 May;262(5):1379-84. doi: 10.1007/s00415-015-7766-8. Epub 2015 May 10.

18.

Histopathology and clinical course of MOG-antibody-associated encephalomyelitis.

Spadaro M, Gerdes LA, Mayer MC, Ertl-Wagner B, Laurent S, Krumbholz M, Breithaupt C, Högen T, Straube A, Giese A, Hohlfeld R, Lassmann H, Meinl E, Kümpfel T.

Ann Clin Transl Neurol. 2015 Mar;2(3):295-301. doi: 10.1002/acn3.164. Epub 2015 Jan 14.

19.

Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination.

Mohan H, Friese A, Albrecht S, Krumbholz M, Elliott CL, Arthur A, Menon R, Farina C, Junker A, Stadelmann C, Barnett SC, Huitinga I, Wekerle H, Hohlfeld R, Lassmann H, Kuhlmann T, Linington C, Meinl E.

Acta Neuropathol Commun. 2014 Dec 11;2:168. doi: 10.1186/s40478-014-0168-9.

20.

Interferon beta and vitamin D synergize to induce immunoregulatory receptors on peripheral blood monocytes of multiple sclerosis patients.

Waschbisch A, Sanderson N, Krumbholz M, Vlad G, Theil D, Schwab S, Mäurer M, Derfuss T.

PLoS One. 2014 Dec 31;9(12):e115488. doi: 10.1371/journal.pone.0115488. eCollection 2014.

21.

The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity.

Hoffmann FS, Kuhn PH, Laurent SA, Hauck SM, Berer K, Wendlinger SA, Krumbholz M, Khademi M, Olsson T, Dreyling M, Pfister HW, Alexander T, Hiepe F, Kümpfel T, Crawford HC, Wekerle H, Hohlfeld R, Lichtenthaler SF, Meinl E.

J Immunol. 2015 Jan 15;194(2):542-52. doi: 10.4049/jimmunol.1402070. Epub 2014 Dec 10.

22.

Response monitoring of infant acute myeloid leukemia treatment by quantification of the tumor specific MLL-FNBP1 fusion gene.

Krumbholz M, Jung R, Bradtke J, Reinhardt D, Stachel D, Metzler M.

Leuk Lymphoma. 2015 Mar;56(3):793-6. doi: 10.3109/10428194.2014.928933. Epub 2014 Jul 17. No abstract available.

PMID:
24884312
23.

B cells in MS and NMO: pathogenesis and therapy.

Krumbholz M, Meinl E.

Semin Immunopathol. 2014 May;36(3):339-50. doi: 10.1007/s00281-014-0424-x. Epub 2014 May 16. Review.

PMID:
24832354
24.

Sustained complete molecular remission after imatinib discontinuation in children with chronic myeloid leukemia.

Moser O, Krumbholz M, Thiede C, Tauer JT, Janz I, Lauten M, Dilloo D, Metzler M, Suttorp M.

Pediatr Blood Cancer. 2014 Nov;61(11):2080-2. doi: 10.1002/pbc.25090. Epub 2014 May 9.

PMID:
24810322
25.

DNA copy number alterations mark disease progression in paediatric chronic myeloid leukaemia.

van der Sligte NE, Krumbholz M, Pastorczak A, Scheijen B, Tauer JT, Nowasz C, Sonneveld E, de Bock GH, Meeuwsen-de Boer TG, van Reijmersdal S, Kuiper RP, Bradtke J, Metzler M, Suttorp M, de Bont ES, van Leeuwen FN.

Br J Haematol. 2014 Jul;166(2):250-3. doi: 10.1111/bjh.12850. Epub 2014 Mar 27. Erratum in: Br J Haematol. 2014 Nov;167(4):584.

PMID:
24673583
26.

Weibull-distributed dyke thickness reflects probabilistic character of host-rock strength.

Krumbholz M, Hieronymus CF, Burchardt S, Troll VR, Tanner DC, Friese N.

Nat Commun. 2014;5:3272. doi: 10.1038/ncomms4272.

27.

Disease-specific molecular events in cortical multiple sclerosis lesions.

Fischer MT, Wimmer I, Höftberger R, Gerlach S, Haider L, Zrzavy T, Hametner S, Mahad D, Binder CJ, Krumbholz M, Bauer J, Bradl M, Lassmann H.

Brain. 2013 Jun;136(Pt 6):1799-815. doi: 10.1093/brain/awt110. Epub 2013 May 17.

28.

Genomic EWS-FLI1 fusion sequences in Ewing sarcoma resemble breakpoint characteristics of immature lymphoid malignancies.

Berger M, Dirksen U, Braeuninger A, Koehler G, Juergens H, Krumbholz M, Metzler M.

PLoS One. 2013;8(2):e56408. doi: 10.1371/journal.pone.0056408. Epub 2013 Feb 18.

29.

Fingolimod reduces recurrence of disease activity after natalizumab withdrawal in multiple sclerosis.

Havla J, Tackenberg B, Hellwig K, Meinl I, Krumbholz M, Seitz F, Eienbröker C, Gold R, Hohlfeld R, Kleiter I, Kümpfel T.

J Neurol. 2013 May;260(5):1382-7. doi: 10.1007/s00415-012-6808-8. Epub 2012 Dec 25.

PMID:
23266894
30.

Identification of the genomic BCR-ABL1 fusion sequence from blood specimen stored on filter paper.

Karl M, Krumbholz M, Tauer JT, Jacobs U, Metzler M, Suttorp M.

Leuk Res. 2013 Jan;37(1):117-9. doi: 10.1016/j.leukres.2012.10.007. Epub 2012 Nov 3.

PMID:
23127356
31.

Co-occurrence of two cases of progressive multifocal leukoencephalopathy in a natalizumab "infusion group".

Havla J, Berthele A, Kümpfel T, Krumbholz M, Jochim A, Kronsbein H, Ryschkewitsch C, Jensen P, Lippmann K, Hemmer B, Major E, Hohlfeld R.

Mult Scler. 2013 Aug;19(9):1213-5. doi: 10.1177/1352458512466165. Epub 2012 Nov 1.

PMID:
23124790
32.

Headache in patients with pituitary adenoma: clinical and paraclinical findings.

Schankin CJ, Reifferscheid AK, Krumbholz M, Linn J, Rachinger W, Langer S, Sostak P, Arzberger T, Kretzschmar H, Straube A.

Cephalalgia. 2012 Dec;32(16):1198-207. doi: 10.1177/0333102412462639. Epub 2012 Oct 11.

PMID:
23059488
33.

B cells and antibodies in multiple sclerosis pathogenesis and therapy.

Krumbholz M, Derfuss T, Hohlfeld R, Meinl E.

Nat Rev Neurol. 2012 Nov 5;8(11):613-23. doi: 10.1038/nrneurol.2012.203. Epub 2012 Oct 9. Review.

PMID:
23045237
34.

Novel MLL2 mutation in Kabuki syndrome with hypogammaglobulinemia and severe chronic thrombopenia.

Brackmann F, Krumbholz M, Langer T, Rascher W, Holter W, Metzler M.

J Pediatr Hematol Oncol. 2013 Oct;35(7):e314-6. doi: 10.1097/MPH.0b013e3182707fa8.

PMID:
23042018
35.

Genomic BCR-ABL1 breakpoints in pediatric chronic myeloid leukemia.

Krumbholz M, Karl M, Tauer JT, Thiede C, Rascher W, Suttorp M, Metzler M.

Genes Chromosomes Cancer. 2012 Nov;51(11):1045-53. doi: 10.1002/gcc.21989. Epub 2012 Aug 9.

PMID:
22887688
36.

Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration.

Colombo E, Cordiglieri C, Melli G, Newcombe J, Krumbholz M, Parada LF, Medico E, Hohlfeld R, Meinl E, Farina C.

J Exp Med. 2012 Mar 12;209(3):521-35. doi: 10.1084/jem.20110698. Epub 2012 Mar 5.

37.

Familial Mediterranean fever-associated mutation pyrin E148Q as a potential risk factor for multiple sclerosis.

Kümpfel T, Gerdes LA, Wacker T, Blaschek A, Havla J, Krumbholz M, Pöllmann W, Feneberg W, Hohlfeld R, Lohse P.

Mult Scler. 2012 Sep;18(9):1229-38. doi: 10.1177/1352458512437813. Epub 2012 Feb 15.

PMID:
22337722
38.

Prospects of transcript profiling for mRNAs and MicroRNAs using formalin-fixed and paraffin-embedded dissected autoptic multiple sclerosis lesions.

Eisele S, Krumbholz M, Fischer MT, Mohan H, Junker A, Arzberger T, Hohlfeld R, Bradl M, Lassmann H, Meinl E.

Brain Pathol. 2012 Sep;22(5):607-18. doi: 10.1111/j.1750-3639.2012.00564.x. Epub 2012 Feb 13.

PMID:
22233114
39.

Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis.

Pröbstel AK, Dornmair K, Bittner R, Sperl P, Jenne D, Magalhaes S, Villalobos A, Breithaupt C, Weissert R, Jacob U, Krumbholz M, Kuempfel T, Blaschek A, Stark W, Gärtner J, Pohl D, Rostasy K, Weber F, Forne I, Khademi M, Olsson T, Brilot F, Tantsis E, Dale RC, Wekerle H, Hohlfeld R, Banwell B, Bar-Or A, Meinl E, Derfuss T.

Neurology. 2011 Aug 9;77(6):580-8. doi: 10.1212/WNL.0b013e318228c0b1. Epub 2011 Jul 27.

PMID:
21795651
40.

Long-term follow-up of patients with neuromyelitis optica after repeated therapy with rituximab.

Pellkofer HL, Krumbholz M, Berthele A, Hemmer B, Gerdes LA, Havla J, Bittner R, Canis M, Meinl E, Hohlfeld R, Kuempfel T.

Neurology. 2011 Apr 12;76(15):1310-5. doi: 10.1212/WNL.0b013e3182152881.

PMID:
21482945
41.

De-escalation from natalizumab in multiple sclerosis: recurrence of disease activity despite switching to glatiramer acetate.

Havla J, Gerdes LA, Meinl I, Krumbholz M, Faber H, Weber F, Pellkofer HL, Hohlfeld R, Kümpfel T.

J Neurol. 2011 Sep;258(9):1665-9. doi: 10.1007/s00415-011-5996-y. Epub 2011 Mar 23.

PMID:
21431380
42.

Humoral autoimmunity in multiple sclerosis.

Meinl E, Derfuss T, Krumbholz M, Pröbstel AK, Hohlfeld R.

J Neurol Sci. 2011 Jul 15;306(1-2):180-2. doi: 10.1016/j.jns.2010.08.009. Epub 2010 Sep 3. Review.

PMID:
20817206
43.

Intracellular ROS level is increased in fibroblasts of triple A syndrome patients.

Kind B, Koehler K, Krumbholz M, Landgraf D, Huebner A.

J Mol Med (Berl). 2010 Dec;88(12):1233-42. doi: 10.1007/s00109-010-0661-y. Epub 2010 Aug 13.

PMID:
20706703
44.

Extracellular matrix in multiple sclerosis lesions: Fibrillar collagens, biglycan and decorin are upregulated and associated with infiltrating immune cells.

Mohan H, Krumbholz M, Sharma R, Eisele S, Junker A, Sixt M, Newcombe J, Wekerle H, Hohlfeld R, Lassmann H, Meinl E.

Brain Pathol. 2010 Sep;20(5):966-75. doi: 10.1111/j.1750-3639.2010.00399.x. Epub 2010 Mar 25.

PMID:
20456365
45.

Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment.

Jung R, Jacobs U, Krumbholz M, Langer T, Keller T, De Lorenzo P, Valsecchi MG, van der Velden VH, Moericke A, Stanulla M, Teigler-Schlegel A, Panzer-Gruemayer ER, van Dongen JJ, Schrappe M, den Boer ML, Pieters R, Rascher W, Metzler M.

Leukemia. 2010 Apr;24(4):903-7. doi: 10.1038/leu.2010.14. Epub 2010 Feb 18. No abstract available.

PMID:
20164851
46.

MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47.

Junker A, Krumbholz M, Eisele S, Mohan H, Augstein F, Bittner R, Lassmann H, Wekerle H, Hohlfeld R, Meinl E.

Brain. 2009 Dec;132(Pt 12):3342-52. doi: 10.1093/brain/awp300.

PMID:
19952055
47.

Headache in patients with a meningioma correlates with a bone-invasive growth pattern but not with cytokine expression.

Schankin CJ, Krumbholz M, Sostak P, Reinisch VM, Goldbrunner R, Straube A.

Cephalalgia. 2010 Apr;30(4):413-24. doi: 10.1111/j.1468-2982.2009.01945.x. Epub 2010 Mar 9.

PMID:
19614683
48.

Netting neutrophils in autoimmune small-vessel vasculitis.

Kessenbrock K, Krumbholz M, Schönermarck U, Back W, Gross WL, Werb Z, Gröne HJ, Brinkmann V, Jenne DE.

Nat Med. 2009 Jun;15(6):623-5. doi: 10.1038/nm.1959.

49.

Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals.

Derfuss T, Parikh K, Velhin S, Braun M, Mathey E, Krumbholz M, Kümpfel T, Moldenhauer A, Rader C, Sonderegger P, Pöllmann W, Tiefenthaller C, Bauer J, Lassmann H, Wekerle H, Karagogeos D, Hohlfeld R, Linington C, Meinl E.

Proc Natl Acad Sci U S A. 2009 May 19;106(20):8302-7. doi: 10.1073/pnas.0901496106. Epub 2009 Apr 28.

50.

Cluster analysis of genomic ETV6-RUNX1 (TEL-AML1) fusion sites in childhood acute lymphoblastic leukemia.

von Goessel H, Jacobs U, Semper S, Krumbholz M, Langer T, Keller T, Schrauder A, van der Velden VH, van Dongen JJ, Harbott J, Panzer-Grümayer ER, Schrappe M, Rascher W, Metzler M.

Leuk Res. 2009 Aug;33(8):1082-8. doi: 10.1016/j.leukres.2008.11.001. Epub 2008 Dec 10.

PMID:
19081626

Supplemental Content

Loading ...
Support Center