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Items: 1 to 20 of 251

1.

Analysis of the genetic basis of height in large Jewish nuclear families.

Zeevi D, Bloom JS, Sadhu MJ, Ben Yehuda A, Zangen D, Levy-Lahad E, Kruglyak L.

PLoS Genet. 2019 Jul 8;15(7):e1008082. doi: 10.1371/journal.pgen.1008082. [Epub ahead of print]

2.

Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk.

Burga A, Ben-David E, Lemus Vergara T, Boocock J, Kruglyak L.

Nat Commun. 2019 Jun 18;10(1):2680. doi: 10.1038/s41467-019-10636-9.

3.

Substrate-Based Allosteric Regulation of a Homodimeric Enzyme.

Mehrabi P, Di Pietrantonio C, Kim TH, Sljoka A, Taverner K, Ing C, Kruglyak N, Pomès R, Pai EF, Prosser RS.

J Am Chem Soc. 2019 Jun 26. doi: 10.1021/jacs.9b03703. [Epub ahead of print]

PMID:
31188575
4.

How Low Can You Go?

Sadhu MJ, Kruglyak L.

CRISPR J. 2018 Oct;1:312-313. doi: 10.1089/crispr.2018.0042. No abstract available.

PMID:
31021269
5.

The Genetic Basis of Mutation Rate Variation in Yeast.

Gou L, Bloom JS, Kruglyak L.

Genetics. 2019 Feb;211(2):731-740. doi: 10.1534/genetics.118.301609. Epub 2018 Nov 30.

6.

Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection.

Lee AY, Ewing AD, Ellrott K, Hu Y, Houlahan KE, Bare JC, Espiritu SMG, Huang V, Dang K, Chong Z, Caloian C, Yamaguchi TN; ICGC-TCGA DREAM Somatic Mutation Calling Challenge Participants, Kellen MR, Chen K, Norman TC, Friend SH, Guinney J, Stolovitzky G, Haussler D, Margolin AA, Stuart JM, Boutros PC.

Genome Biol. 2018 Nov 6;19(1):188. doi: 10.1186/s13059-018-1539-5.

7.

Genetics of trans-regulatory variation in gene expression.

Albert FW, Bloom JS, Siegel J, Day L, Kruglyak L.

Elife. 2018 Jul 17;7. pii: e35471. doi: 10.7554/eLife.35471.

8.

Targeted methylation sequencing of plasma cell-free DNA for cancer detection and classification.

Liu L, Toung JM, Jassowicz AF, Vijayaraghavan R, Kang H, Zhang R, Kruglyak KM, Huang HJ, Hinoue T, Shen H, Salathia NS, Hong DS, Naing A, Subbiah V, Piha-Paul SA, Bibikova M, Granger G, Barnes B, Shen R, Gutekunst K, Fu S, Tsimberidou AM, Lu C, Eng C, Moulder SL, Kopetz ES, Amaria RN, Meric-Bernstam F, Laird PW, Fan JB, Janku F.

Ann Oncol. 2018 Jun 1;29(6):1445-1453. doi: 10.1093/annonc/mdy119.

9.

Highly parallel genome variant engineering with CRISPR-Cas9.

Sadhu MJ, Bloom JS, Day L, Siegel JJ, Kosuri S, Kruglyak L.

Nat Genet. 2018 Apr;50(4):510-514. doi: 10.1038/s41588-018-0087-y. Epub 2018 Apr 9.

10.

Magnonic band spectrum of spin waves in an elliptical helix.

Golovchan AV, Kruglyak VV, Tkachenko VS, Kuchko AN.

R Soc Open Sci. 2018 Jan 31;5(1):172285. doi: 10.1098/rsos.172285. eCollection 2018 Jan.

11.

Genetic variation in adaptability and pleiotropy in budding yeast.

Jerison ER, Kryazhimskiy S, Mitchell JK, Bloom JS, Kruglyak L, Desai MM.

Elife. 2017 Aug 17;6. pii: e27167. doi: 10.7554/eLife.27167.

12.

The genetic basis of natural variation in a phoretic behavior.

Lee D, Yang H, Kim J, Brady S, Zdraljevic S, Zamanian M, Kim H, Paik YK, Kruglyak L, Andersen EC, Lee J.

Nat Commun. 2017 Aug 17;8(1):273. doi: 10.1038/s41467-017-00386-x.

13.

New nanocomposites of polystyrene with polyaniline doped with lauryl sulfuric acid.

Pud AA, Nikolayeva OA, Vretik LO, Noskov YV, Ogurtsov NA, Kruglyak OS, Fedorenko EA.

Nanoscale Res Lett. 2017 Aug 15;12(1):493. doi: 10.1186/s11671-017-2265-8.

14.

A genetic signature of the evolution of loss of flight in the Galapagos cormorant.

Burga A, Wang W, Ben-David E, Wolf PC, Ramey AM, Verdugo C, Lyons K, Parker PG, Kruglyak L.

Science. 2017 Jun 2;356(6341). pii: eaal3345. doi: 10.1126/science.aal3345.

15.

Development and Validation of an Ultradeep Next-Generation Sequencing Assay for Testing of Plasma Cell-Free DNA from Patients with Advanced Cancer.

Janku F, Zhang S, Waters J, Liu L, Huang HJ, Subbiah V, Hong DS, Karp DD, Fu S, Cai X, Ramzanali NM, Madwani K, Cabrilo G, Andrews DL, Zhao Y, Javle M, Kopetz ES, Luthra R, Kim HJ, Gnerre S, Satya RV, Chuang HY, Kruglyak KM, Toung J, Zhao C, Shen R, Heymach JV, Meric-Bernstam F, Mills GB, Fan JB, Salathia NS.

Clin Cancer Res. 2017 Sep 15;23(18):5648-5656. doi: 10.1158/1078-0432.CCR-17-0291. Epub 2017 May 23.

16.

A maternal-effect selfish genetic element in Caenorhabditis elegans.

Ben-David E, Burga A, Kruglyak L.

Science. 2017 Jun 9;356(6342):1051-1055. doi: 10.1126/science.aan0621. Epub 2017 May 11.

17.

Top-down design of magnonic crystals from bottom-up magnetic nanoparticles through protein arrays.

Okuda M, Schwarze T, Eloi JC, Ward Jones SE, Heard PJ, Sarua A, Ahmad E, Kruglyak VV, Grundler D, Schwarzacher W.

Nanotechnology. 2017 Apr 18;28(15):155301. doi: 10.1088/1361-6528/aa62f3. Epub 2017 Mar 15.

PMID:
28294104
18.

Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast.

Forsberg SK, Bloom JS, Sadhu MJ, Kruglyak L, Carlborg Ö.

Nat Genet. 2017 Apr;49(4):497-503. doi: 10.1038/ng.3800. Epub 2017 Feb 27.

19.

Leupeptazin, a highly modified tripeptide isolated from cultures of a Streptomyces sp. inhibits cathepsin K.

Kruglyak N, Williams DE, Chen H, Law S, Kaleta J, Villanueva I, Davies JE, Andersen RJ, Brömme D.

Bioorg Med Chem Lett. 2017 Mar 15;27(6):1397-1400. doi: 10.1016/j.bmcl.2017.02.007. Epub 2017 Feb 5.

PMID:
28228366
20.

Identification of mouse cathepsin K structural elements that regulate the potency of odanacatib.

Law S, Andrault PM, Aguda AH, Nguyen NT, Kruglyak N, Brayer GD, Brömme D.

Biochem J. 2017 Feb 20;474(5):851-864. doi: 10.1042/BCJ20160985.

PMID:
28049758

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