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Items: 1 to 50 of 174

1.

Plasminogen Activator Inhibitor-1 Promotes Neutrophil Infiltration and Tissue Injury on Ischemia-Reperfusion.

Praetner M, Zuchtriegel G, Holzer M, Uhl B, Schaubächer J, Mittmann L, Fabritius M, Fürst R, Zahler S, Funken D, Lerchenberger M, Khandoga A, Kanse S, Lauber K, Krombach F, Reichel CA.

Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):829-842. doi: 10.1161/ATVBAHA.117.309760. Epub 2018 Jan 25.

PMID:
29371242
2.

The surface chemistry determines the spatio-temporal interaction dynamics of quantum dots in atherosclerotic lesions.

Uhl B, Hirn S, Mildner K, Coletti R, Massberg S, Reichel CA, Rehberg M, Zeuschner D, Krombach F.

Nanomedicine (Lond). 2018 Mar;13(6):623-638. doi: 10.2217/nnm-2017-0350. Epub 2018 Jan 15.

PMID:
29334311
3.

Early pulmonary response is critical for extra-pulmonary carbon nanoparticle mediated effects: comparison of inhalation versus intra-arterial infusion exposures in mice.

Ganguly K, Ettehadieh D, Upadhyay S, Takenaka S, Adler T, Karg E, Krombach F, Kreyling WG, Schulz H, Schmid O, Stoeger T.

Part Fibre Toxicol. 2017 Jun 20;14(1):19. doi: 10.1186/s12989-017-0200-x.

4.

Dexamethasone-conjugated DNA nanotubes as anti-inflammatory agents in vivo.

Sellner S, Kocabey S, Zhang T, Nekolla K, Hutten S, Krombach F, Liedl T, Rehberg M.

Biomaterials. 2017 Jul;134:78-90. doi: 10.1016/j.biomaterials.2017.04.031. Epub 2017 Apr 17.

PMID:
28458030
5.

The Endothelial Glycocalyx Controls Interactions of Quantum Dots with the Endothelium and Their Translocation across the Blood-Tissue Border.

Uhl B, Hirn S, Immler R, Mildner K, Möckl L, Sperandio M, Bräuchle C, Reichel CA, Zeuschner D, Krombach F.

ACS Nano. 2017 Feb 28;11(2):1498-1508. doi: 10.1021/acsnano.6b06812. Epub 2017 Feb 7.

PMID:
28135073
6.

The glycocalyx regulates the uptake of nanoparticles by human endothelial cells in vitro.

Möckl L, Hirn S, Torrano AA, Uhl B, Bräuchle C, Krombach F.

Nanomedicine (Lond). 2017 Feb;12(3):207-217. doi: 10.2217/nnm-2016-0332. Epub 2017 Jan 12.

PMID:
28078967
7.

Factor VII-activating protease deficiency promotes neointima formation by enhancing leukocyte accumulation.

Daniel JM, Reichel CA, Schmidt-Woell T, Dutzmann J, Zuchtriegel G, Krombach F, Herold J, Bauersachs J, Sedding DG, Kanse SM.

J Thromb Haemost. 2016 Oct;14(10):2058-2067. doi: 10.1111/jth.13417. Epub 2016 Sep 7.

8.

Aged neutrophils contribute to the first line of defense in the acute inflammatory response.

Uhl B, Vadlau Y, Zuchtriegel G, Nekolla K, Sharaf K, Gaertner F, Massberg S, Krombach F, Reichel CA.

Blood. 2016 Nov 10;128(19):2327-2337. doi: 10.1182/blood-2016-05-718999. Epub 2016 Sep 8.

9.

Platelets Guide Leukocytes to Their Sites of Extravasation.

Zuchtriegel G, Uhl B, Puhr-Westerheide D, Pörnbacher M, Lauber K, Krombach F, Reichel CA.

PLoS Biol. 2016 May 6;14(5):e1002459. doi: 10.1371/journal.pbio.1002459. eCollection 2016 May.

10.

Multiphoton Microscopy of Nonfluorescent Nanoparticles In Vitro and In Vivo.

Dietzel S, Hermann S, Kugel Y, Sellner S, Uhl B, Hirn S, Krombach F, Rehberg M.

Small. 2016 Jun;12(24):3245-57. doi: 10.1002/smll.201503766. Epub 2016 Apr 27.

PMID:
27120195
11.

Influence of Surface Modifications on the Spatiotemporal Microdistribution of Quantum Dots In Vivo.

Nekolla K, Kick K, Sellner S, Mildner K, Zahler S, Zeuschner D, Krombach F, Rehberg M.

Small. 2016 May;12(19):2641-51. doi: 10.1002/smll.201600071. Epub 2016 Mar 29.

PMID:
27028603
12.

Intercellular Transport of Nanomaterials is Mediated by Membrane Nanotubes In Vivo.

Rehberg M, Nekolla K, Sellner S, Praetner M, Mildner K, Zeuschner D, Krombach F.

Small. 2016 Apr 13;12(14):1882-90. doi: 10.1002/smll.201503606. Epub 2016 Feb 8.

PMID:
26854197
13.

DNA nanotubes as intracellular delivery vehicles in vivo.

Sellner S, Kocabey S, Nekolla K, Krombach F, Liedl T, Rehberg M.

Biomaterials. 2015;53:453-63. doi: 10.1016/j.biomaterials.2015.02.099. Epub 2015 Mar 19.

PMID:
25890742
14.

Spatiotemporal expression dynamics of selectins govern the sequential extravasation of neutrophils and monocytes in the acute inflammatory response.

Zuchtriegel G, Uhl B, Hessenauer ME, Kurz AR, Rehberg M, Lauber K, Krombach F, Reichel CA.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):899-910. doi: 10.1161/ATVBAHA.114.305143. Epub 2015 Feb 26.

PMID:
25722429
15.

Proinflammatory and cytotoxic response to nanoparticles in precision-cut lung slices.

Hirn S, Haberl N, Loza K, Epple M, Kreyling WG, Rothen-Rutishauser B, Rehberg M, Krombach F.

Beilstein J Nanotechnol. 2014 Dec 18;5:2440-9. doi: 10.3762/bjnano.5.253. eCollection 2014.

16.

Effects of acute systemic administration of TiO2, ZnO, SiO2, and Ag nanoparticles on hemodynamics, hemostasis and leukocyte recruitment.

Haberl N, Hirn S, Holzer M, Zuchtriegel G, Rehberg M, Krombach F.

Nanotoxicology. 2015;9(8):963-71. doi: 10.3109/17435390.2014.992815. Epub 2015 Feb 11.

PMID:
25670207
17.

Components of the plasminogen activation system promote engraftment of porous polyethylene biomaterial via common and distinct effects.

Reichel CA, Hessenauer ME, Pflieger K, Rehberg M, Kanse SM, Zahler S, Krombach F, Berghaus A, Strieth S.

PLoS One. 2015 Feb 6;10(2):e0116883. doi: 10.1371/journal.pone.0116883. eCollection 2015.

18.

Synchronized renal tubular cell death involves ferroptosis.

Linkermann A, Skouta R, Himmerkus N, Mulay SR, Dewitz C, De Zen F, Prokai A, Zuchtriegel G, Krombach F, Welz PS, Weinlich R, Vanden Berghe T, Vandenabeele P, Pasparakis M, Bleich M, Weinberg JM, Reichel CA, Bräsen JH, Kunzendorf U, Anders HJ, Stockwell BR, Green DR, Krautwald S.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16836-41. doi: 10.1073/pnas.1415518111. Epub 2014 Nov 10.

19.

PVP-coated, negatively charged silver nanoparticles: A multi-center study of their physicochemical characteristics, cell culture and in vivo experiments.

Ahlberg S, Antonopulos A, Diendorf J, Dringen R, Epple M, Flöck R, Goedecke W, Graf C, Haberl N, Helmlinger J, Herzog F, Heuer F, Hirn S, Johannes C, Kittler S, Köller M, Korn K, Kreyling WG, Krombach F, Lademann J, Loza K, Luther EM, Malissek M, Meinke MC, Nordmeyer D, Pailliart A, Raabe J, Rancan F, Rothen-Rutishauser B, Rühl E, Schleh C, Seibel A, Sengstock C, Treuel L, Vogt A, Weber K, Zellner R.

Beilstein J Nanotechnol. 2014 Nov 3;5:1944-65. doi: 10.3762/bjnano.5.205. eCollection 2014. Review.

20.

Tissue plasminogen activator promotes postischemic neutrophil recruitment via its proteolytic and nonproteolytic properties.

Uhl B, Zuchtriegel G, Puhr-Westerheide D, Praetner M, Rehberg M, Fabritius M, Hessenauer M, Holzer M, Khandoga A, Fürst R, Zahler S, Krombach F, Reichel CA.

Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1495-504. doi: 10.1161/ATVBAHA.114.303721. Epub 2014 Apr 24.

PMID:
24764453
21.

Carbon-based nanomaterials accelerate arteriolar thrombus formation in the murine microcirculation independently of their shape.

Holzer M, Bihari P, Praetner M, Uhl B, Reichel C, Fent J, Vippola M, Lakatos S, Krombach F.

J Appl Toxicol. 2014 Nov;34(11):1167-76. doi: 10.1002/jat.2996. Epub 2014 Feb 14.

PMID:
24531921
22.

Cytotoxic and proinflammatory effects of PVP-coated silver nanoparticles after intratracheal instillation in rats.

Haberl N, Hirn S, Wenk A, Diendorf J, Epple M, Johnston BD, Krombach F, Kreyling WG, Schleh C.

Beilstein J Nanotechnol. 2013 Dec 19;4:933-40. doi: 10.3762/bjnano.4.105. eCollection 2013 Dec 19.

23.

Targeting platelet migration in the postischemic liver by blocking protease-activated receptor 4.

Mende K, Reifart J, Rosentreter D, Manukyan D, Mayr D, Krombach F, Rentsch M, Khandoga A.

Transplantation. 2014 Jan 27;97(2):154-60. doi: 10.1097/01.TP.0000437430.89485.a0.

PMID:
24434483
24.

Matrix metalloproteinases modulate ameboid-like migration of neutrophils through inflamed interstitial tissue.

Lerchenberger M, Uhl B, Stark K, Zuchtriegel G, Eckart A, Miller M, Puhr-Westerheide D, Praetner M, Rehberg M, Khandoga AG, Lauber K, Massberg S, Krombach F, Reichel CA.

Blood. 2013 Aug 1;122(5):770-80. doi: 10.1182/blood-2012-12-472944. Epub 2013 Jun 11.

25.

Transient targeting of phosphoinositide 3-kinase acts as a roadblock in mast cells' route to allergy.

Collmann E, Bohnacker T, Marone R, Dawson J, Rehberg M, Stringer R, Krombach F, Burkhart C, Hirsch E, Hollingworth GJ, Thomas M, Wymann MP.

J Allergy Clin Immunol. 2013 Oct;132(4):959-68. doi: 10.1016/j.jaci.2013.03.008. Epub 2013 May 14.

PMID:
23683463
26.

Endogenous and exogenous pentraxin-3 limits postischemic acute and chronic kidney injury.

Lech M, Römmele C, Gröbmayr R, Eka Susanti H, Kulkarni OP, Wang S, Gröne HJ, Uhl B, Reichel C, Krombach F, Garlanda C, Mantovani A, Anders HJ.

Kidney Int. 2013 Apr;83(4):647-61. doi: 10.1038/ki.2012.463. Epub 2013 Jan 16.

27.

Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung.

Ittner A, Block H, Reichel CA, Varjosalo M, Gehart H, Sumara G, Gstaiger M, Krombach F, Zarbock A, Ricci R.

J Exp Med. 2012 Nov 19;209(12):2229-46. doi: 10.1084/jem.20120677. Epub 2012 Nov 5.

28.

At the interface of fibrinolysis and inflammation: the role of urokinase-type plasminogen activator in the leukocyte extravasation cascade.

Reichel CA, Kanse SM, Krombach F.

Trends Cardiovasc Med. 2012 Oct;22(7):192-6. doi: 10.1016/j.tcm.2012.07.019. Epub 2012 Oct 10. Review.

PMID:
23062972
29.

Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4.

Allam R, Scherbaum CR, Darisipudi MN, Mulay SR, Hägele H, Lichtnekert J, Hagemann JH, Rupanagudi KV, Ryu M, Schwarzenberger C, Hohenstein B, Hugo C, Uhl B, Reichel CA, Krombach F, Monestier M, Liapis H, Moreth K, Schaefer L, Anders HJ.

J Am Soc Nephrol. 2012 Aug;23(8):1375-88. doi: 10.1681/ASN.2011111077. Epub 2012 Jun 7.

30.

C-C motif chemokine CCL3 and canonical neutrophil attractants promote neutrophil extravasation through common and distinct mechanisms.

Reichel CA, Puhr-Westerheide D, Zuchtriegel G, Uhl B, Berberich N, Zahler S, Wymann MP, Luckow B, Krombach F.

Blood. 2012 Jul 26;120(4):880-90. doi: 10.1182/blood-2012-01-402164. Epub 2012 Jun 6.

PMID:
22674804
31.

Surface chemistry of quantum dots determines their behavior in postischemic tissue.

Rehberg M, Leite CF, Mildner K, Horstkotte J, Zeuschner D, Krombach F.

ACS Nano. 2012 Feb 28;6(2):1370-9. doi: 10.1021/nn204187c. Epub 2012 Jan 24.

PMID:
22243127
32.

Label-free 3D visualization of cellular and tissue structures in intact muscle with second and third harmonic generation microscopy.

Rehberg M, Krombach F, Pohl U, Dietzel S.

PLoS One. 2011;6(11):e28237. doi: 10.1371/journal.pone.0028237. Epub 2011 Nov 28.

33.

A novel approach to prevent endothelial hyperpermeability: the Crataegus extract WS® 1442 targets the cAMP/Rap1 pathway.

Bubik MF, Willer EA, Bihari P, Jürgenliemk G, Ammer H, Krombach F, Zahler S, Vollmar AM, Fürst R.

J Mol Cell Cardiol. 2012 Jan;52(1):196-205. doi: 10.1016/j.yjmcc.2011.10.020. Epub 2011 Oct 31.

PMID:
22085704
34.

Urokinase-type plasminogen activator promotes paracellular transmigration of neutrophils via Mac-1, but independently of urokinase-type plasminogen activator receptor.

Reichel CA, Uhl B, Lerchenberger M, Puhr-Westerheide D, Rehberg M, Liebl J, Khandoga A, Schmalix W, Zahler S, Deindl E, Lorenzl S, Declerck PJ, Kanse S, Krombach F.

Circulation. 2011 Oct 25;124(17):1848-59. doi: 10.1161/CIRCULATIONAHA.110.017012. Epub 2011 Oct 3.

PMID:
21969013
35.

Inhibitor of apoptosis proteins as novel targets in inflammatory processes.

Mayer BA, Rehberg M, Erhardt A, Wolf A, Reichel CA, Kracht M, Krombach F, Tiegs G, Zahler S, Vollmar AM, Fürst R.

Arterioscler Thromb Vasc Biol. 2011 Oct;31(10):2240-50. doi: 10.1161/ATVBAHA.111.234294. Epub 2011 Aug 4.

PMID:
21817100
36.

Roscovitine blocks leukocyte extravasation by inhibition of cyclin-dependent kinases 5 and 9.

Berberich N, Uhl B, Joore J, Schmerwitz UK, Mayer BA, Reichel CA, Krombach F, Zahler S, Vollmar AM, Fürst R.

Br J Pharmacol. 2011 Jul;163(5):1086-98. doi: 10.1111/j.1476-5381.2011.01309.x.

37.

Plasmin inhibitors prevent leukocyte accumulation and remodeling events in the postischemic microvasculature.

Reichel CA, Lerchenberger M, Uhl B, Rehberg M, Berberich N, Zahler S, Wymann MP, Krombach F.

PLoS One. 2011 Feb 22;6(2):e17229. doi: 10.1371/journal.pone.0017229.

38.

Flavopiridol protects against inflammation by attenuating leukocyte-endothelial interaction via inhibition of cyclin-dependent kinase 9.

Schmerwitz UK, Sass G, Khandoga AG, Joore J, Mayer BA, Berberich N, Totzke F, Krombach F, Tiegs G, Zahler S, Vollmar AM, Fürst R.

Arterioscler Thromb Vasc Biol. 2011 Feb;31(2):280-8. doi: 10.1161/ATVBAHA.110.213934. Epub 2010 Nov 18.

PMID:
21088252
39.

von Willebrand factor promotes leukocyte extravasation.

Petri B, Broermann A, Li H, Khandoga AG, Zarbock A, Krombach F, Goerge T, Schneider SW, Jones C, Nieswandt B, Wild MK, Vestweber D.

Blood. 2010 Nov 25;116(22):4712-9. doi: 10.1182/blood-2010-03-276311. Epub 2010 Aug 17.

PMID:
20716766
40.

Quantum dots modulate leukocyte adhesion and transmigration depending on their surface modification.

Rehberg M, Praetner M, Leite CF, Reichel CA, Bihari P, Mildner K, Duhr S, Zeuschner D, Krombach F.

Nano Lett. 2010 Sep 8;10(9):3656-64. doi: 10.1021/nl102100m.

PMID:
20695477
41.

The contribution of the capillary endothelium to blood clearance and tissue deposition of anionic quantum dots in vivo.

Praetner M, Rehberg M, Bihari P, Lerchenberger M, Uhl B, Holzer M, Eichhorn ME, Fürst R, Perisic T, Reichel CA, Welsch U, Krombach F.

Biomaterials. 2010 Sep;31(26):6692-700. doi: 10.1016/j.biomaterials.2010.05.051. Epub 2010 Jun 17.

PMID:
20619783
42.

CD99 and CD99L2 act at the same site as, but independently of, PECAM-1 during leukocyte diapedesis.

Bixel MG, Li H, Petri B, Khandoga AG, Khandoga A, Zarbock A, Wolburg-Buchholz K, Wolburg H, Sorokin L, Zeuschner D, Maerz S, Butz S, Krombach F, Vestweber D.

Blood. 2010 Aug 19;116(7):1172-84. doi: 10.1182/blood-2009-12-256388. Epub 2010 May 17.

PMID:
20479283
43.

Signal improvement in multiphoton microscopy by reflection with simple mirrors near the sample.

Rehberg M, Krombach F, Pohl U, Dietzel S.

J Biomed Opt. 2010 Mar-Apr;15(2):026017. doi: 10.1117/1.3374337.

44.

Platelet adhesion and fibrinogen deposition in murine microvessels upon inhalation of nanosized carbon particles.

Khandoga A, Stoeger T, Khandoga AG, Bihari P, Karg E, Ettehadieh D, Lakatos S, Fent J, Schulz H, Krombach F.

J Thromb Haemost. 2010 Jul;8(7):1632-40. doi: 10.1111/j.1538-7836.2010.03904.x. Epub 2010 May 4.

45.

Double-stranded DNA activates glomerular endothelial cells and enhances albumin permeability via a toll-like receptor-independent cytosolic DNA recognition pathway.

Hägele H, Allam R, Pawar RD, Reichel CA, Krombach F, Anders HJ.

Am J Pathol. 2009 Nov;175(5):1896-904. doi: 10.2353/ajpath.2009.090182. Epub 2009 Oct 15.

46.

Single-walled carbon nanotubes activate platelets and accelerate thrombus formation in the microcirculation.

Bihari P, Holzer M, Praetner M, Fent J, Lerchenberger M, Reichel CA, Rehberg M, Lakatos S, Krombach F.

Toxicology. 2010 Mar 10;269(2-3):148-54. doi: 10.1016/j.tox.2009.08.011. Epub 2009 Aug 19.

PMID:
19698757
47.

Resident dendritic cells prevent postischemic acute renal failure by help of single Ig IL-1 receptor-related protein.

Lech M, Avila-Ferrufino A, Allam R, Segerer S, Khandoga A, Krombach F, Garlanda C, Mantovani A, Anders HJ.

J Immunol. 2009 Sep 15;183(6):4109-18. doi: 10.4049/jimmunol.0900118. Epub 2009 Aug 19.

48.

Ccl2 and Ccl3 mediate neutrophil recruitment via induction of protein synthesis and generation of lipid mediators.

Reichel CA, Rehberg M, Lerchenberger M, Berberich N, Bihari P, Khandoga AG, Zahler S, Krombach F.

Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1787-93. doi: 10.1161/ATVBAHA.109.193268. Epub 2009 Jul 16.

PMID:
19608967
49.

Beta-arrestin 2 is required for the induction and strengthening of integrin-mediated leukocyte adhesion during CXCR2-driven extravasation.

Molteni R, Crespo CL, Feigelson S, Moser C, Fabbri M, Grabovsky V, Krombach F, Laudanna C, Alon R, Pardi R.

Blood. 2009 Jul 30;114(5):1073-82. doi: 10.1182/blood-2008-10-183699. Epub 2009 May 8.

PMID:
19429870
50.

In vivo imaging and quantitative analysis of leukocyte directional migration and polarization in inflamed tissue.

Khandoga AG, Khandoga A, Reichel CA, Bihari P, Rehberg M, Krombach F.

PLoS One. 2009;4(3):e4693. doi: 10.1371/journal.pone.0004693. Epub 2009 Mar 4.

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