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Items: 1 to 50 of 264

1.

Expression of Slc35f1 in the murine brain.

Farenholtz J, Artelt N, Blumenthal A, Endlich K, Kroemer HK, Endlich N, von Bohlen Und Halbach O.

Cell Tissue Res. 2019 Mar 13. doi: 10.1007/s00441-019-03008-8. [Epub ahead of print]

PMID:
30868340
2.

Release of Platelet-Derived Sphingosine-1-Phosphate Involves Multidrug Resistance Protein 4 (MRP4/ABCC4) and Is Inhibited by Statins.

Vogt K, Mahajan-Thakur S, Wolf R, Bröderdorf S, Vogel C, Böhm A, Ritter CA, Gräler M, Oswald S, Greinacher A, Kroemer HK, Jedlitschky G, Rauch BH.

Thromb Haemost. 2018 Jan;118(1):132-142. doi: 10.1160/TH17-04-0291. Epub 2018 Jan 5.

PMID:
29304533
3.

Doxorubicin enhances oxysterol levels resulting in a LXR-mediated upregulation of cardiac cholesterol transporters.

Monzel JV, Budde T, Meyer Zu Schwabedissen HE, Schwebe M, Bien-Möller S, Lütjohann D, Kroemer HK, Jedlitschky G, Grube M.

Biochem Pharmacol. 2017 Nov 15;144:108-119. doi: 10.1016/j.bcp.2017.08.008. Epub 2017 Aug 12.

PMID:
28807695
4.

Open letter on access to the BIA 10-2474 clinical trial data.

Brøsen K, Funck-Brentano C, Kroemer HK, Pirmohamed M, Schwab M.

Lancet. 2017 Jan 14;389(10065):156. doi: 10.1016/S0140-6736(16)32515-6. Epub 2016 Dec 10. No abstract available.

PMID:
27955829
5.

Several adaptor proteins promote intracellular localisation of the transporter MRP4/ABCC4 in platelets and haematopoietic cells.

Schaletzki Y, Kromrey ML, Bröderdorf S, Hammer E, Grube M, Hagen P, Sucic S, Freissmuth M, Völker U, Greinacher A, Rauch BH, Kroemer HK, Jedlitschky G.

Thromb Haemost. 2017 Jan 5;117(1):105-115. doi: 10.1160/TH16-01-0045. Epub 2016 Oct 20.

PMID:
27761583
6.

Expression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial Therapy.

Hubeny A, Keiser M, Oswald S, Jedlitschky G, Kroemer HK, Siegmund W, Grube M.

Drug Metab Dispos. 2016 Oct;44(10):1562-8. doi: 10.1124/dmd.116.069807. Epub 2016 Aug 8.

PMID:
27504015
7.

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.

Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen MH, Pers TH, Johnson AD, Ko YA, Fuchsberger C, Tayo B, Nalls M, Feitosa MF, Isaacs A, Dehghan A, d'Adamo P, Adeyemo A, Dieffenbach AK, Zonderman AB, Nolte IM, van der Most PJ, Wright AF, Shuldiner AR, Morrison AC, Hofman A, Smith AV, Dreisbach AW, Franke A, Uitterlinden AG, Metspalu A, Tonjes A, Lupo A, Robino A, Johansson Å, Demirkan A, Kollerits B, Freedman BI, Ponte B, Oostra BA, Paulweber B, Krämer BK, Mitchell BD, Buckley BM, Peralta CA, Hayward C, Helmer C, Rotimi CN, Shaffer CM, Müller C, Sala C, van Duijn CM, Saint-Pierre A, Ackermann D, Shriner D, Ruggiero D, Toniolo D, Lu Y, Cusi D, Czamara D, Ellinghaus D, Siscovick DS, Ruderfer D, Gieger C, Grallert H, Rochtchina E, Atkinson EJ, Holliday EG, Boerwinkle E, Salvi E, Bottinger EP, Murgia F, Rivadeneira F, Ernst F, Kronenberg F, Hu FB, Navis GJ, Curhan GC, Ehret GB, Homuth G, Coassin S, Thun GA, Pistis G, Gambaro G, Malerba G, Montgomery GW, Eiriksdottir G, Jacobs G, Li G, Wichmann HE, Campbell H, Schmidt H, Wallaschofski H, Völzke H, Brenner H, Kroemer HK, Kramer H, Lin H, Leach IM, Ford I, Guessous I, Rudan I, Prokopenko I, Borecki I, Heid IM, Kolcic I, Persico I, Jukema JW, Wilson JF, Felix JF, Divers J, Lambert JC, Stafford JM, Gaspoz JM, Smith JA, Faul JD, Wang JJ, Ding J, Hirschhorn JN, Attia J, Whitfield JB, Chalmers J, Viikari J, Coresh J, Denny JC, Karjalainen J, Fernandes JK, Endlich K, Butterbach K, Keene KL, Lohman K, Portas L, Launer LJ, Lyytikäinen LP, Yengo L, Franke L, Ferrucci L, Rose LM, Kedenko L, Rao M, Struchalin M, Kleber ME, Cavalieri M, Haun M, Cornelis MC, Ciullo M, Pirastu M, de Andrade M, McEvoy MA, Woodward M, Adam M, Cocca M, Nauck M, Imboden M, Waldenberger M, Pruijm M, Metzger M, Stumvoll M, Evans MK, Sale MM, Kähönen M, Boban M, Bochud M, Rheinberger M, Verweij N, Bouatia-Naji N, Martin NG, Hastie N, Probst-Hensch N, Soranzo N, Devuyst O, Raitakari O, Gottesman O, Franco OH, Polasek O, Gasparini P, Munroe PB, Ridker PM, Mitchell P, Muntner P, Meisinger C, Smit JH; ICBP Consortium; AGEN Consortium; CARDIOGRAM; CHARGe-Heart Failure Group; ECHOGen Consortium, Kovacs P, Wild PS, Froguel P, Rettig R, Mägi R, Biffar R, Schmidt R, Middelberg RP, Carroll RJ, Penninx BW, Scott RJ, Katz R, Sedaghat S, Wild SH, Kardia SL, Ulivi S, Hwang SJ, Enroth S, Kloiber S, Trompet S, Stengel B, Hancock SJ, Turner ST, Rosas SE, Stracke S, Harris TB, Zeller T, Zemunik T, Lehtimäki T, Illig T, Aspelund T, Nikopensius T, Esko T, Tanaka T, Gyllensten U, Völker U, Emilsson V, Vitart V, Aalto V, Gudnason V, Chouraki V, Chen WM, Igl W, März W, Koenig W, Lieb W, Loos RJ, Liu Y, Snieder H, Pramstaller PP, Parsa A, O'Connell JR, Susztak K, Hamet P, Tremblay J, de Boer IH, Böger CA, Goessling W, Chasman DI, Köttgen A, Kao WH, Fox CS.

Nat Commun. 2016 Jan 21;7:10023. doi: 10.1038/ncomms10023.

8.

Protective effects of endothelin receptor A and B inhibitors against doxorubicin-induced cardiomyopathy.

Schwebe M, Ameling S, Hammer E, Monzel JV, Bonitz K, Budde S, Schult K, Oswald S, Scheuch E, Grube M, Poesch A, Budde T, Ewert R, Schroeder HW, Kroemer HK, Bien-Möller S.

Biochem Pharmacol. 2015 Mar 15;94(2):109-29. doi: 10.1016/j.bcp.2015.01.014. Epub 2015 Feb 7.

PMID:
25660617
9.

Function-impairing polymorphisms of the hepatic uptake transporter SLCO1B1 modify the therapeutic efficacy of statins in a population-based cohort.

Meyer zu Schwabedissen HE, Albers M, Baumeister SE, Rimmbach C, Nauck M, Wallaschofski H, Siegmund W, Völzke H, Kroemer HK.

Pharmacogenet Genomics. 2015 Jan;25(1):8-18. doi: 10.1097/FPC.0000000000000098.

PMID:
25379722
10.

Creatine kinase elevation caused by a combination of fluvastatin and telmisartan in a patient heterozygous for the CYP2C9*3 and ABCC2 -24C > T variants: a case report.

Meyer zu Schwabedissen HE, Siegmund W, Kroemer HK, Rollnik JD.

BMC Res Notes. 2014 Oct 3;7:688. doi: 10.1186/1756-0500-7-688.

11.

Transcriptional regulation of urate transportosome member SLC2A9 by nuclear receptor HNF4α.

Prestin K, Wolf S, Feldtmann R, Hussner J, Geissler I, Rimmbach C, Kroemer HK, Zimmermann U, Meyer zu Schwabedissen HE.

Am J Physiol Renal Physiol. 2014 Nov 1;307(9):F1041-51. doi: 10.1152/ajprenal.00640.2013. Epub 2014 Sep 10.

12.

Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival.

Herzog S, Fink MA, Weitmann K, Friedel C, Hadlich S, Langner S, Kindermann K, Holm T, Böhm A, Eskilsson E, Miletic H, Hildner M, Fritsch M, Vogelgesang S, Havemann C, Ritter CA, Meyer zu Schwabedissen HE, Rauch B, Hoffmann W, Kroemer HK, Schroeder H, Bien-Möller S.

Neuro Oncol. 2015 Feb;17(2):223-42. doi: 10.1093/neuonc/nou216. Epub 2014 Aug 25.

13.

cAMP regulates expression of the cyclic nucleotide transporter MRP4 (ABCC4) through the EPAC pathway.

Bröderdorf S, Zang S, Schaletzki Y, Grube M, Kroemer HK, Jedlitschky G.

Pharmacogenet Genomics. 2014 Oct;24(10):522-6. doi: 10.1097/FPC.0000000000000084.

PMID:
25121519
14.

Cohort profile: Greifswald approach to individualized medicine (GANI_MED).

Grabe HJ, Assel H, Bahls T, Dörr M, Endlich K, Endlich N, Erdmann P, Ewert R, Felix SB, Fiene B, Fischer T, Flessa S, Friedrich N, Gadebusch-Bondio M, Salazar MG, Hammer E, Haring R, Havemann C, Hecker M, Hoffmann W, Holtfreter B, Kacprowski T, Klein K, Kocher T, Kock H, Krafczyk J, Kuhn J, Langanke M, Lendeckel U, Lerch MM, Lieb W, Lorbeer R, Mayerle J, Meissner K, zu Schwabedissen HM, Nauck M, Ott K, Rathmann W, Rettig R, Richardt C, Saljé K, Schminke U, Schulz A, Schwab M, Siegmund W, Stracke S, Suhre K, Ueffing M, Ungerer S, Völker U, Völzke H, Wallaschofski H, Werner V, Zygmunt MT, Kroemer HK.

J Transl Med. 2014 May 23;12:144. doi: 10.1186/1479-5876-12-144.

15.

Incidence of all-cause and cardiovascular mortality predicted by symmetric dimethylarginine in the population-based study of health in pomerania.

Schwedhelm E, Wallaschofski H, Atzler D, Dörr M, Nauck M, Völker U, Kroemer HK, Völzke H, Böger RH, Friedrich N.

PLoS One. 2014 May 12;9(5):e96875. doi: 10.1371/journal.pone.0096875. eCollection 2014.

16.

[Cardiology: innovative medicine from molecular diagnosis to modern interventional technology].

Kroemer HK, Hasenfuß G, Erdmann E.

Dtsch Med Wochenschr. 2014 Apr;139(16):821. doi: 10.1055/s-0034-1369978. Epub 2014 Apr 10. German. No abstract available.

PMID:
24722930
17.

[Personalized medicine in cardiology?].

Kroemer HK, Hasenfuß G.

Herz. 2014 Mar;39(2):177. doi: 10.1007/s00059-014-4082-5. German. No abstract available.

PMID:
24623569
18.

Cell-specific expression of uptake transporters--a potential approach for cardiovascular drug delivery devices.

Meyer Zu Schwabedissen HE, Begunk R, Hussner J, Juhnke BO, Gliesche D, Böttcher K, Sternberg K, Schmitz KP, Kroemer HK.

Mol Pharm. 2014 Mar 3;11(3):665-72. doi: 10.1021/mp400245g. Epub 2014 Feb 19.

PMID:
24495124
19.

Antibodies against potassium channel interacting protein 2 induce necrosis in isolated rat cardiomyocytes.

Choudhury S, Schnell M, Bühler T, Reinke Y, Lüdemann J, Nießner F, Brinkmeier H, Herda LR, Staudt A, Kroemer HK, Völker U, Felix SB, Landsberger M.

J Cell Biochem. 2014 Apr;115(4):678-89. doi: 10.1002/jcb.24707.

PMID:
24453044
20.

Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme.

Oberstadt MC, Bien-Möller S, Weitmann K, Herzog S, Hentschel K, Rimmbach C, Vogelgesang S, Balz E, Fink M, Michael H, Zeden JP, Bruckmüller H, Werk AN, Cascorbi I, Hoffmann W, Rosskopf D, Schroeder HW, Kroemer HK.

BMC Cancer. 2013 Dec 31;13:617. doi: 10.1186/1471-2407-13-617.

21.

Tooth loss, periodontitis, and statins in a population-based follow-up study.

Meisel P, Kroemer HK, Nauck M, Holtfreter B, Kocher T.

J Periodontol. 2014 Jun;85(6):e160-8. doi: 10.1902/jop.2013.130456. Epub 2013 Dec 5.

PMID:
24304227
22.

Aspirin inhibits release of platelet-derived sphingosine-1-phosphate in acute myocardial infarction.

Polzin A, Rassaf T, Böhm A, Lüth A, Kleuser B, Zeus T, Kelm M, Kroemer HK, Schrör K, Rauch BH.

Int J Cardiol. 2013 Dec 10;170(2):e23-4. doi: 10.1016/j.ijcard.2013.10.050. Epub 2013 Oct 16. No abstract available.

PMID:
24169533
23.

OATP1B3 is expressed in pancreatic β-islet cells and enhances the insulinotropic effect of the sulfonylurea derivative glibenclamide.

Meyer Zu Schwabedissen HE, Boettcher K, Steiner T, Schwarz UI, Keiser M, Kroemer HK, Siegmund W.

Diabetes. 2014 Feb;63(2):775-84. doi: 10.2337/db13-1005. Epub 2013 Oct 22.

24.

A new, accurate predictive model for incident hypertension.

Völzke H, Fung G, Ittermann T, Yu S, Baumeister SE, Dörr M, Lieb W, Völker U, Linneberg A, Jørgensen T, Felix SB, Rettig R, Rao B, Kroemer HK.

J Hypertens. 2013 Nov;31(11):2142-50; discussion 2150. doi: 10.1097/HJH.0b013e328364a16d.

PMID:
24077244
25.

Common variants in Mendelian kidney disease genes and their association with renal function.

Parsa A, Fuchsberger C, Köttgen A, O'Seaghdha CM, Pattaro C, de Andrade M, Chasman DI, Teumer A, Endlich K, Olden M, Chen MH, Tin A, Kim YJ, Taliun D, Li M, Feitosa M, Gorski M, Yang Q, Hundertmark C, Foster MC, Glazer N, Isaacs A, Rao M, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, Tönjes A, Dehghan A, Couraki V, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Kollerits B, Pistis G, Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Hofer E, Hu F, Demirkan A, Oostra BA, Turner ST, Ding J, Andrews JS, Freedman BI, Giulianini F, Koenig W, Illig T, Döring A, Wichmann HE, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Stengel B, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Colhoun H, Doney A, Robino A, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, van Duijn CM, Borecki I, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman J, Hayward C, Ridker PM, Bochud M, Heid IM, Siscovick DS, Fox CS, Kao WL, Böger CA.

J Am Soc Nephrol. 2013 Dec;24(12):2105-17. doi: 10.1681/ASN.2012100983. Epub 2013 Sep 12.

26.

Genome-wide association study of chronic periodontitis in a general German population.

Teumer A, Holtfreter B, Völker U, Petersmann A, Nauck M, Biffar R, Völzke H, Kroemer HK, Meisel P, Homuth G, Kocher T.

J Clin Periodontol. 2013 Nov;40(11):977-85. doi: 10.1111/jcpe.12154. Epub 2013 Sep 11.

PMID:
24024966
27.

Implant-associated local drug delivery systems based on biodegradable polymers: customized designs for different medical applications.

Sternberg K, Petersen S, Grabow N, Senz V, Meyer zu Schwabedissen H, Kroemer HK, Schmitz KP.

Biomed Tech (Berl). 2013 Oct;58(5):417-27. doi: 10.1515/bmt-2012-0049. Review.

PMID:
23979120
28.

Protease-activated receptor-2 regulates the innate immune response to viral infection in a coxsackievirus B3-induced myocarditis.

Weithauser A, Bobbert P, Antoniak S, Böhm A, Rauch BH, Klingel K, Savvatis K, Kroemer HK, Tschope C, Stroux A, Zeichhardt H, Poller W, Mackman N, Schultheiss HP, Rauch U.

J Am Coll Cardiol. 2013 Nov 5;62(19):1737-45. doi: 10.1016/j.jacc.2013.05.076. Epub 2013 Jul 17.

29.

In vitro study of dual drug-eluting stents with locally focused sirolimus and atorvastatin release.

Petersen S, Hussner J, Reske T, Grabow N, Senz V, Begunk R, Arbeiter D, Kroemer HK, Schmitz KP, Meyer zu Schwabedissen HE, Sternberg K.

J Mater Sci Mater Med. 2013 Nov;24(11):2589-600. doi: 10.1007/s10856-013-5001-7. Epub 2013 Jul 12.

PMID:
23846839
30.

Targeting CNS transporters for treatment of neurodegenerative diseases.

Jedlitschky G, Grube M, Mosyagin I, Kroemer HK, Vogelgesang S.

Curr Pharm Des. 2014;20(10):1523-33.

PMID:
23789959
31.

Identification of genetic loci associated with Helicobacter pylori serologic status.

Mayerle J, den Hoed CM, Schurmann C, Stolk L, Homuth G, Peters MJ, Capelle LG, Zimmermann K, Rivadeneira F, Gruska S, Völzke H, de Vries AC, Völker U, Teumer A, van Meurs JB, Steinmetz I, Nauck M, Ernst F, Weiss FU, Hofman A, Zenker M, Kroemer HK, Prokisch H, Uitterlinden AG, Lerch MM, Kuipers EJ.

JAMA. 2013 May 8;309(18):1912-20. doi: 10.1001/jama.2013.4350. Erratum in: JAMA. 2013 Jul 3;310(1):99. Kuipers, Ernst [corrected to Kuipers, Ernst J].

PMID:
23652523
32.

Personalized cardiovascular medicine: concepts and methodological considerations.

Völzke H, Schmidt CO, Baumeister SE, Ittermann T, Fung G, Krafczyk-Korth J, Hoffmann W, Schwab M, Meyer zu Schwabedissen HE, Dörr M, Felix SB, Lieb W, Kroemer HK.

Nat Rev Cardiol. 2013 Jun;10(6):308-16. doi: 10.1038/nrcardio.2013.35. Epub 2013 Mar 26. Review.

PMID:
23528962
33.

[Research projects for implementation of individualized medicine].

Lieb W, Grabe HJ, Kroemer HK.

Dtsch Med Wochenschr. 2013 Mar;138(13):665-6. doi: 10.1055/s-0032-1332928. Epub 2013 Mar 19. German. No abstract available.

PMID:
23512371
34.

Myocardial gene expression profiles and cardiodepressant autoantibodies predict response of patients with dilated cardiomyopathy to immunoadsorption therapy.

Ameling S, Herda LR, Hammer E, Steil L, Teumer A, Trimpert C, Dörr M, Kroemer HK, Klingel K, Kandolf R, Völker U, Felix SB.

Eur Heart J. 2013 Mar;34(9):666-75. doi: 10.1093/eurheartj/ehs330. Epub 2012 Oct 25.

35.

Advances in coronary stent technology--active drug-loaded stent surfaces for prevention of restenosis and improvement of biocompatibility.

Sternberg K, Grabow N, Petersen S, Weitschies W, Harder C, Ince H, Kroemer HK, Schmitz KP.

Curr Pharm Biotechnol. 2013;14(1):76-90. Review.

PMID:
23092260
36.

In vitro dissolution testing of drug-eluting stents.

Seidlitz A, Nagel S, Semmling B, Sternberg K, Kroemer HK, Weitschies W.

Curr Pharm Biotechnol. 2013;14(1):67-75. Review.

PMID:
23092259
37.

Molecular changes in the early phase of renin-dependent cardiac hypertrophy in hypertensive cyp1a1ren-2 transgenic rats.

Kunert-Keil C, Landsberger M, Jantzen F, Niessner F, Kroemer HK, Felix SB, Brinkmeier H, Peters J.

J Renin Angiotensin Aldosterone Syst. 2013 Mar;14(1):41-50. doi: 10.1177/1470320312460070. Epub 2012 Oct 11.

PMID:
23060473
38.

Steroid hormones specifically modify the activity of organic anion transporting polypeptides.

Koenen A, Köck K, Keiser M, Siegmund W, Kroemer HK, Grube M.

Eur J Pharm Sci. 2012 Nov 20;47(4):774-80. doi: 10.1016/j.ejps.2012.08.017. Epub 2012 Sep 8.

PMID:
22982504
39.

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.

Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Böger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa MF, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, Tönjes A, Dehghan A, Lambert JC, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Coassin S, Pistis G; CARDIoGRAM Consortium; ICBP Consortium; CARe Consortium; WTCCC2, Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu F, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Giulianini F, Koenig W, Illig T, Meisinger C, Gieger C, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Stengel B, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Duijn CM, Borecki IB, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman J, Hayward C, Ridker PM, Parsa A, Bochud M, Heid IM, Kao WH, Fox CS, Köttgen A.

Hum Mol Genet. 2012 Dec 15;21(24):5329-43. doi: 10.1093/hmg/dds369. Epub 2012 Sep 8.

40.

Potentially relevant incidental findings on research whole-body MRI in the general adult population: frequencies and management.

Hegenscheid K, Seipel R, Schmidt CO, Völzke H, Kühn JP, Biffar R, Kroemer HK, Hosten N, Puls R.

Eur Radiol. 2013 Mar;23(3):816-26. doi: 10.1007/s00330-012-2636-6. Epub 2012 Aug 22.

PMID:
22911290
41.

Population imaging as valuable tool for personalized medicine.

Völzke H, Schmidt CO, Hegenscheid K, Kühn JP, Bamberg F, Lieb W, Kroemer HK, Hosten N, Puls R.

Clin Pharmacol Ther. 2012 Oct;92(4):422-4. doi: 10.1038/clpt.2012.100. Epub 2012 Aug 22. Review. Erratum in: Clin Pharmacol Ther. 2013 Jan;93(1):129.

PMID:
22910443
42.

Strategies for personalized medicine-based research and implementation in the clinical workflow.

Lieb W, Völzke H, Pulley JM, Roden DM, Kroemer HK.

Clin Pharmacol Ther. 2012 Oct;92(4):443-5. doi: 10.1038/clpt.2012.119. Epub 2012 Aug 22. Review.

PMID:
22910438
43.

The German Centre for Cardiovascular Research.

Prendergast B, Coope LT, Crijns H, Falkenstein E, Fölsch U, Halvorsen S, Janssens S, Jokinen E, Kroemer HK, Lücke A, Murer H, Nagel E, Neyses L, Perk J, Probst-Hensch N, Rietschel ET, Rütten H, Steingen C, Tedgui A, van Gilst W, Eschenhagen T, Kristensen SD.

Eur Heart J. 2012 May;33(9):1033-36,1036a. No abstract available.

PMID:
22893891
44.

Heart rate reduction by ivabradine improves aortic compliance in apolipoprotein E-deficient mice.

Custodis F, Fries P, Müller A, Stamm C, Grube M, Kroemer HK, Böhm M, Laufs U.

J Vasc Res. 2012;49(5):432-40. doi: 10.1159/000339547. Epub 2012 Jul 3.

45.

Variants of Toll-like receptor 4 predict cardiac recovery in patients with dilated cardiomyopathy.

Riad A, Meyer zu Schwabedissen H, Weitmann K, Herda LR, Dörr M, Empen K, Kieback A, Hummel A, Reinthaler M, Grube M, Klingel K, Nauck M, Kandolf R, Hoffmann W, Kroemer HK, Felix SB.

J Biol Chem. 2012 Aug 3;287(32):27236-43. doi: 10.1074/jbc.M112.369728. Epub 2012 May 29.

46.

Compartment-specific gene regulation of the CAR inducer efavirenz in vivo.

Meyer zu Schwabedissen HE, Oswald S, Bresser C, Nassif A, Modess C, Desta Z, Ogburn ET, Marinova M, Lütjohann D, Spielhagen C, Nauck M, Kroemer HK, Siegmund W.

Clin Pharmacol Ther. 2012 Jul;92(1):103-11. doi: 10.1038/clpt.2012.34. Epub 2012 May 16. Erratum in: Clin Pharmacol Ther. 2013 Jan;93(1):129. Dosage error in article text.

47.

Genome-wide association and functional follow-up reveals new loci for kidney function.

Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, Fuchsberger C, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa M, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson Å, Tönjes A, Dehghan A, Chouraki V, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Kollerits B, Pistis G; CARDIoGRAM Consortium; ICBP Consortium; CARe Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2), Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu FB, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Koenig W, Illig T, Döring A, Wichmann HE, Kolcic I, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Endlich K, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Giulianini F, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Metzger M, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Duijn CM, Borecki I, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman JC, Hayward C, Ridker P, Parsa A, Bochud M, Heid IM, Goessling W, Chasman DI, Kao WH, Fox CS.

PLoS Genet. 2012;8(3):e1002584. doi: 10.1371/journal.pgen.1002584. Epub 2012 Mar 29.

48.

Transporters in human platelets: physiologic function and impact for pharmacotherapy.

Jedlitschky G, Greinacher A, Kroemer HK.

Blood. 2012 Apr 12;119(15):3394-402. doi: 10.1182/blood-2011-09-336933. Epub 2012 Feb 14. Review.

49.

Regulation of interferon-inducible proteins by doxorubicin via interferon γ-Janus tyrosine kinase-signal transducer and activator of transcription signaling in tumor cells.

Hussner J, Ameling S, Hammer E, Herzog S, Steil L, Schwebe M, Niessen J, Schroeder HW, Kroemer HK, Ritter CA, Völker U, Bien S.

Mol Pharmacol. 2012 May;81(5):679-88. doi: 10.1124/mol.111.075994. Epub 2012 Feb 9.

PMID:
22323498
50.

Impact of efavirenz on intestinal metabolism and transport: insights from an interaction study with ezetimibe in healthy volunteers.

Oswald S, Meyer zu Schwabedissen HE, Nassif A, Modess C, Desta Z, Ogburn ET, Mostertz J, Keiser M, Jia J, Hubeny A, Ulrich A, Runge D, Marinova M, Lütjohann D, Kroemer HK, Siegmund W.

Clin Pharmacol Ther. 2012 Mar;91(3):506-13. doi: 10.1038/clpt.2011.255. Epub 2012 Feb 1.

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