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Items: 1 to 50 of 1132

1.

The hallmarks of successful anticancer immunotherapy.

Galluzzi L, Chan TA, Kroemer G, Wolchok JD, López-Soto A.

Sci Transl Med. 2018 Sep 19;10(459). pii: eaat7807. doi: 10.1126/scitranslmed.aat7807. Review.

PMID:
30232229
2.

TumGrowth: An open-access web tool for the statistical analysis of tumor growth curves.

Enot DP, Vacchelli E, Jacquelot N, Zitvogel L, Kroemer G.

Oncoimmunology. 2018 Aug 1;7(9):e1462431. doi: 10.1080/2162402X.2018.1462431. eCollection 2018.

3.

Immune effectors responsible for the elimination of hyperploid cancer cells.

Aranda F, Chaba K, Bloy N, Garcia P, Bordenave C, Martins I, Stoll G, Tesniere A, Kroemer G, Senovilla L.

Oncoimmunology. 2018 May 21;7(8):e1463947. doi: 10.1080/2162402X.2018.1463947. eCollection 2018.

PMID:
30221060
4.

Heating it up: Oncolytic viruses make tumors 'hot' and suitable for checkpoint blockade immunotherapies.

Gujar S, Pol JG, Kroemer G.

Oncoimmunology. 2018 Mar 13;7(8):e1442169. doi: 10.1080/2162402X.2018.1442169. eCollection 2018.

5.

Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles.

Bonora M, Wieckowski MR, Sinclair DA, Kroemer G, Pinton P, Galluzzi L.

Nat Rev Cardiol. 2018 Sep 3. doi: 10.1038/s41569-018-0074-0. [Epub ahead of print] Review.

PMID:
30177752
6.

Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism.

Bárcena C, Quirós PM, Durand S, Mayoral P, Rodríguez F, Caravia XM, Mariño G, Garabaya C, Fernández-García MT, Kroemer G, Freije JMP, López-Otín C.

Cell Rep. 2018 Aug 28;24(9):2392-2403. doi: 10.1016/j.celrep.2018.07.089.

7.

MDM2-TP53 Crossregulation: An Underestimated Target to Promote Loss of TP53 Function and Cell Survival.

Soussi T, Kroemer G.

Trends Cancer. 2018 Sep;4(9):602-605. doi: 10.1016/j.trecan.2018.07.001. Epub 2018 Jul 21.

PMID:
30149877
8.

Redaporfin induces immunogenic cell death by selective destruction of the endoplasmic reticulum and the Golgi apparatus.

Gomes-da-Silva LC, Zhao L, Arnaut LG, Kroemer G, Kepp O.

Oncotarget. 2018 Jul 27;9(58):31169-31170. doi: 10.18632/oncotarget.25798. eCollection 2018 Jul 27. No abstract available.

9.

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing.

Boland B, Yu WH, Corti O, Mollereau B, Henriques A, Bezard E, Pastores GM, Rubinsztein DC, Nixon RA, Duchen MR, Mallucci GR, Kroemer G, Levine B, Eskelinen EL, Mochel F, Spedding M, Louis C, Martin OR, Millan MJ.

Nat Rev Drug Discov. 2018 Sep;17(9):660-688. doi: 10.1038/nrd.2018.109. Epub 2018 Aug 17. Review.

PMID:
30116051
10.

PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism.

Li C, Zhang Y, Cheng X, Yuan H, Zhu S, Liu J, Wen Q, Xie Y, Liu J, Kroemer G, Klionsky DJ, Lotze MT, Zeh HJ, Kang R, Tang D.

Dev Cell. 2018 Aug 20;46(4):441-455.e8. doi: 10.1016/j.devcel.2018.07.012. Epub 2018 Aug 9.

PMID:
30100261
11.

Spermidine delays aging in humans.

Madeo F, Carmona-Gutierrez D, Kepp O, Kroemer G.

Aging (Albany NY). 2018 Aug 6;10(8):2209-2211. doi: 10.18632/aging.101517. No abstract available.

12.

The anticancer peptide RT53 induces immunogenic cell death.

Pasquereau-Kotula E, Habault J, Kroemer G, Poyet JL.

PLoS One. 2018 Aug 6;13(8):e0201220. doi: 10.1371/journal.pone.0201220. eCollection 2018.

13.

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc- Activity.

Song X, Zhu S, Chen P, Hou W, Wen Q, Liu J, Xie Y, Liu J, Klionsky DJ, Kroemer G, Lotze MT, Zeh HJ, Kang R, Tang D.

Curr Biol. 2018 Aug 6;28(15):2388-2399.e5. doi: 10.1016/j.cub.2018.05.094. Epub 2018 Jul 26.

PMID:
30057310
14.

Higher spermidine intake is linked to lower mortality: a prospective population-based study.

Kiechl S, Pechlaner R, Willeit P, Notdurfter M, Paulweber B, Willeit K, Werner P, Ruckenstuhl C, Iglseder B, Weger S, Mairhofer B, Gartner M, Kedenko L, Chmelikova M, Stekovic S, Stuppner H, Oberhollenzer F, Kroemer G, Mayr M, Eisenberg T, Tilg H, Madeo F, Willeit J.

Am J Clin Nutr. 2018 Aug 1;108(2):371-380. doi: 10.1093/ajcn/nqy102.

PMID:
29955838
15.

Reply to 'F508del-CFTR is not corrected by thymosin α1'.

Romani L, Stincardini C, Giovagnoli S, Paci M, Villella VR, Sforna L, Renga G, Bellet MM, Costantini C, Puccetti P, Kroemer G, Maiuri L, Pessia M, Goldstein A, Garaci E.

Nat Med. 2018 Jul;24(7):891-893. doi: 10.1038/s41591-018-0080-0. No abstract available.

PMID:
29942090
16.

Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations.

Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Sklar LA, Allers L, Garcia SA, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, Eskelinen EL, Fourie B, Gozuacik D, Hong W, Hotamisligi G, Jäättelä M, Jo EK, Johansen T, Juhász G, Kimchi A, Ktistakis N, Kroemer G, MIzushima N, Münz C, Reggiori F, Rubinsztein D, Ryan K, Schroder K, Simonsen A, Tooze S, I Vaccaro M, Yoshimori T, Yu L, Zhang H, Klionsky DJ.

Autophagy. 2018;14(6):925-929. doi: 10.1080/15548627.2018.1465784.

PMID:
29938597
17.

Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis.

Kang R, Zeng L, Zhu S, Xie Y, Liu J, Wen Q, Cao L, Xie M, Ran Q, Kroemer G, Wang H, Billiar TR, Jiang J, Tang D.

Cell Host Microbe. 2018 Jul 11;24(1):97-108.e4. doi: 10.1016/j.chom.2018.05.009. Epub 2018 Jun 21.

PMID:
29937272
18.

Publisher Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.

Romani L, Oikonomou V, Moretti S, Iannitti RG, D'Adamo MC, Villella VR, Pariano M, Sforna L, Borghi M, Bellet MM, Fallarino F, Pallotta MT, Servillo G, Ferrari E, Puccetti P, Kroemer G, Pessia M, Maiuri L, Goldstein AL, Garaci E.

Nat Med. 2018 Sep;24(9):1482. doi: 10.1038/s41591-018-0099-2.

PMID:
29934535
19.

Author Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.

Romani L, Oikonomou V, Moretti S, Iannitti RG, D'Adamo MC, Villella VR, Pariano M, Sforna L, Borghi M, Bellet MM, Fallarino F, Pallotta MT, Servillo G, Ferrari E, Puccetti P, Kroemer G, Pessia M, Maiuri L, Goldstein AL, Garaci E.

Nat Med. 2018 Sep;24(9):1481. doi: 10.1038/s41591-018-0100-0.

PMID:
29934534
20.

Aspirin-another caloric-restriction mimetic.

Pietrocola F, Castoldi F, Maiuri MC, Kroemer G.

Autophagy. 2018 Jul 18:1-2. doi: 10.1080/15548627.2018.1454810. [Epub ahead of print]

PMID:
29929449
21.

Author Correction: IMMP2L: a mitochondrial protease suppressing cellular senescence.

Sica V, Kroemer G.

Cell Res. 2018 Jul;28(7):782. doi: 10.1038/s41422-018-0059-x.

22.

Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death.

Martins I, Raza SQ, Voisin L, Dakhli H, Allouch A, Law F, Sabino D, De Jong D, Thoreau M, Mintet E, Dugué D, Piacentini M, Gougeon ML, Jaulin F, Bertrand P, Brenner C, Ojcius DM, Kroemer G, Modjtahedi N, Deutsch E, Perfettini JL.

Cell Death Dis. 2018 Jun 18;9(7):716. doi: 10.1038/s41419-018-0747-y.

23.

Metabolic vulnerability of cisplatin-resistant cancers.

Obrist F, Michels J, Durand S, Chery A, Pol J, Levesque S, Joseph A, Astesana V, Pietrocola F, Wu GS, Castedo M, Kroemer G.

EMBO J. 2018 Jul 13;37(14). pii: e98597. doi: 10.15252/embj.201798597. Epub 2018 Jun 6.

PMID:
29875130
24.

The intestinal microbiota determines the clinical efficacy of immune checkpoint blockers targeting PD-1/PD-L1.

Derosa L, Routy B, Kroemer G, Zitvogel L.

Oncoimmunology. 2018 Apr 18;7(6):e1434468. doi: 10.1080/2162402X.2018.1434468. eCollection 2018.

PMID:
29872574
25.

Trial Watch: Immunostimulation with recombinant cytokines for cancer therapy.

García-Martínez E, Smith M, Buqué A, Aranda F, de la Peña FA, Ivars A, Cánovas MS, Conesa MAV, Fucikova J, Spisek R, Zitvogel L, Kroemer G, Galluzzi L.

Oncoimmunology. 2018 Feb 15;7(6):e1433982. doi: 10.1080/2162402X.2018.1433982. eCollection 2018. Review.

PMID:
29872569
26.

Epigenetic anticancer agents cause HMGB1 release in vivo.

Liu P, Zhao L, Loos F, Iribarren K, Kepp O, Kroemer G.

Oncoimmunology. 2018 Feb 14;7(6):e1431090. doi: 10.1080/2162402X.2018.1431090. eCollection 2018.

PMID:
29872561
27.

eIF2α phosphorylation: A hallmark of immunogenic cell death.

Bezu L, Sauvat A, Humeau J, Leduc M, Kepp O, Kroemer G.

Oncoimmunology. 2018 Feb 14;7(6):e1431089. doi: 10.1080/2162402X.2018.1431089. eCollection 2018.

PMID:
29872560
28.

TFAM is a novel mediator of immunogenic cancer cell death.

Yang M, Li C, Zhu S, Cao L, Kroemer G, Zeh H, Tang D, Kang R.

Oncoimmunology. 2018 Feb 15;7(6):e1431086. doi: 10.1080/2162402X.2018.1431086. eCollection 2018.

29.

Aspirin induces autophagy via inhibition of the acetyltransferase EP300.

Castoldi F, Pietrocola F, Maiuri MC, Kroemer G.

Oncotarget. 2018 May 15;9(37):24574-24575. doi: 10.18632/oncotarget.25364. eCollection 2018 May 15. No abstract available.

30.

IMMP2L: a mitochondrial protease suppressing cellular senescence.

Sica V, Kroemer G.

Cell Res. 2018 Jun;28(6):607-608. doi: 10.1038/s41422-018-0051-5. No abstract available. Erratum in: Cell Res. 2018 Jul;28(7):782.

PMID:
29844577
31.

Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus.

Gomes-da-Silva LC, Zhao L, Bezu L, Zhou H, Sauvat A, Liu P, Durand S, Leduc M, Souquere S, Loos F, Mondragón L, Sveinbjørnsson B, Rekdal Ø, Boncompain G, Perez F, Arnaut LG, Kepp O, Kroemer G.

EMBO J. 2018 Jul 2;37(13). pii: e98354. doi: 10.15252/embj.201798354. Epub 2018 May 28.

PMID:
29807932
32.

The tumor suppressor protein p53 and the ferroptosis network.

Kang R, Kroemer G, Tang D.

Free Radic Biol Med. 2018 May 23. pii: S0891-5849(18)30907-9. doi: 10.1016/j.freeradbiomed.2018.05.074. [Epub ahead of print] Review.

PMID:
29800655
33.

TG2 regulates the heat-shock response by the post-translational modification of HSF1.

Rossin F, Villella VR, D'Eletto M, Farrace MG, Esposito S, Ferrari E, Monzani R, Occhigrossi L, Pagliarini V, Sette C, Cozza G, Barlev NA, Falasca L, Fimia GM, Kroemer G, Raia V, Maiuri L, Piacentini M.

EMBO Rep. 2018 Jul;19(7). pii: e45067. doi: 10.15252/embr.201745067. Epub 2018 May 11.

PMID:
29752334
34.

The gut microbiota influences anticancer immunosurveillance and general health.

Routy B, Gopalakrishnan V, Daillère R, Zitvogel L, Wargo JA, Kroemer G.

Nat Rev Clin Oncol. 2018 Jun;15(6):382-396. doi: 10.1038/s41571-018-0006-2. Review.

PMID:
29636538
35.

Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids.

Sauvat A, Chen G, Müller K, Tong M, Aprahamian F, Durand S, Cerrato G, Bezu L, Leduc M, Franz J, Rockenfeller P, Sadoshima J, Madeo F, Kepp O, Kroemer G.

EBioMedicine. 2018 Apr;30:261-272. doi: 10.1016/j.ebiom.2018.03.028. Epub 2018 Mar 27.

36.

Anti-CTLA-4 immunotherapy: uncoupling toxicity and efficacy.

Pol J, Kroemer G.

Cell Res. 2018 May;28(5):501-502. doi: 10.1038/s41422-018-0031-9. Epub 2018 Mar 28. No abstract available.

PMID:
29593340
37.

The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies.

Zitvogel L, Ma Y, Raoult D, Kroemer G, Gajewski TF.

Science. 2018 Mar 23;359(6382):1366-1370. doi: 10.1126/science.aar6918. Review.

PMID:
29567708
38.

Organoids for Modeling Genetic Diseases.

Perez-Lanzon M, Kroemer G, Maiuri MC.

Int Rev Cell Mol Biol. 2018;337:49-81. doi: 10.1016/bs.ircmb.2017.12.006. Epub 2018 Feb 12.

PMID:
29551162
39.

Aspirin Recapitulates Features of Caloric Restriction.

Pietrocola F, Castoldi F, Markaki M, Lachkar S, Chen G, Enot DP, Durand S, Bossut N, Tong M, Malik SA, Loos F, Dupont N, Mariño G, Abdelkader N, Madeo F, Maiuri MC, Kroemer R, Codogno P, Sadoshima J, Tavernarakis N, Kroemer G.

Cell Rep. 2018 Feb 27;22(9):2395-2407. doi: 10.1016/j.celrep.2018.02.024.

40.

Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere.

Abrahão J, Silva L, Silva LS, Khalil JYB, Rodrigues R, Arantes T, Assis F, Boratto P, Andrade M, Kroon EG, Ribeiro B, Bergier I, Seligmann H, Ghigo E, Colson P, Levasseur A, Kroemer G, Raoult D, La Scola B.

Nat Commun. 2018 Feb 27;9(1):749. doi: 10.1038/s41467-018-03168-1.

41.

The autophagic network and cancer.

Rybstein MD, Bravo-San Pedro JM, Kroemer G, Galluzzi L.

Nat Cell Biol. 2018 Mar;20(3):243-251. doi: 10.1038/s41556-018-0042-2. Epub 2018 Feb 23. Review.

PMID:
29476153
42.

Bax inhibitor-1 protects from nonalcoholic steatohepatitis by limiting inositol-requiring enzyme 1 alpha signaling in mice.

Lebeaupin C, Vallée D, Rousseau D, Patouraux S, Bonnafous S, Adam G, Luciano F, Luci C, Anty R, Iannelli A, Marchetti S, Kroemer G, Lacas-Gervais S, Tran A, Gual P, Bailly-Maitre B.

Hepatology. 2018 Aug;68(2):515-532. doi: 10.1002/hep.29847. Epub 2018 May 18.

PMID:
29457838
43.

Evaluation of autophagy inducers in epithelial cells carrying the ΔF508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR.

Zhang S, Stoll G, Pedro JMBS, Sica V, Sauvat A, Obrist F, Kepp O, Li Y, Maiuri L, Zamzami N, Kroemer G.

Cell Death Dis. 2018 Feb 7;9(2):191. doi: 10.1038/s41419-017-0235-9.

44.

Cancer immunotherapy in 2017: The breakthrough of the microbiota.

Kroemer G, Zitvogel L.

Nat Rev Immunol. 2018 Jan 30;18(2):87-88. doi: 10.1038/nri.2018.4. No abstract available.

PMID:
29379189
45.

Spermidine in health and disease.

Madeo F, Eisenberg T, Pietrocola F, Kroemer G.

Science. 2018 Jan 26;359(6374). pii: eaan2788. doi: 10.1126/science.aan2788. Review.

PMID:
29371440
46.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

47.

eIF2α phosphorylation is pathognomonic for immunogenic cell death.

Bezu L, Sauvat A, Humeau J, Gomes-da-Silva LC, Iribarren K, Forveille S, Garcia P, Zhao L, Liu P, Zitvogel L, Senovilla L, Kepp O, Kroemer G.

Cell Death Differ. 2018 Aug;25(8):1375-1393. doi: 10.1038/s41418-017-0044-9. Epub 2018 Jan 22.

PMID:
29358668
48.

Guidelines and recommendations on yeast cell death nomenclature.

Carmona-Gutierrez D, Bauer MA, Zimmermann A, Aguilera A, Austriaco N, Ayscough K, Balzan R, Bar-Nun S, Barrientos A, Belenky P, Blondel M, Braun RJ, Breitenbach M, Burhans WC, Büttner S, Cavalieri D, Chang M, Cooper KF, Côrte-Real M, Costa V, Cullin C, Dawes I, Dengjel J, Dickman MB, Eisenberg T, Fahrenkrog B, Fasel N, Fröhlich KU, Gargouri A, Giannattasio S, Goffrini P, Gourlay CW, Grant CM, Greenwood MT, Guaragnella N, Heger T, Heinisch J, Herker E, Herrmann JM, Hofer S, Jiménez-Ruiz A, Jungwirth H, Kainz K, Kontoyiannis DP, Ludovico P, Manon S, Martegani E, Mazzoni C, Megeney LA, Meisinger C, Nielsen J, Nyström T, Osiewacz HD, Outeiro TF, Park HO, Pendl T, Petranovic D, Picot S, Polčic P, Powers T, Ramsdale M, Rinnerthaler M, Rockenfeller P, Ruckenstuhl C, Schaffrath R, Segovia M, Severin FF, Sharon A, Sigrist SJ, Sommer-Ruck C, Sousa MJ, Thevelein JM, Thevissen K, Titorenko V, Toledano MB, Tuite M, Vögtle FN, Westermann B, Winderickx J, Wissing S, Wölfl S, Zhang ZJ, Zhao RY, Zhou B, Galluzzi L, Kroemer G, Madeo F.

Microb Cell. 2018 Jan 1;5(1):4-31. doi: 10.15698/mic2018.01.607. Review.

49.

Lysosome-targeting agents in cancer therapy.

Kroemer G, Galluzzi L.

Oncotarget. 2017 Oct 3;8(68):112168-112169. doi: 10.18632/oncotarget.21451. eCollection 2017 Dec 22.

50.

Correction for Gyrd-Hansen et al., "Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway by Caspase-9".

Gyrd-Hansen M, Farkas T, Fehrenbacher N, Bastholm L, Høyer-Hansen M, Elling F, Wallach D, Flavell R, Kroemer G, Nylandsted J, Jäättelä M.

Mol Cell Biol. 2017 Dec 29;38(2). pii: e00563-17. doi: 10.1128/MCB.00563-17. Print 2018 Jan 15. No abstract available.

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