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Items: 1 to 50 of 1245

1.

Immunological Effects of Epigenetic Modifiers.

Bezu L, Chuang AW, Liu P, Kroemer G, Kepp O.

Cancers (Basel). 2019 Dec 1;11(12). pii: E1911. doi: 10.3390/cancers11121911. Review.

2.

Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity.

Bravo-San Pedro JM, Sica V, Martins I, Pol J, Loos F, Maiuri MC, Durand S, Bossut N, Aprahamian F, Anagnostopoulos G, Niso-Santano M, Aranda F, Ramírez-Pardo I, Lallement J, Denom J, Boedec E, Gorwood P, Ramoz N, Clément K, Pelloux V, Rohia A, Pattou F, Raverdy V, Caiazzo R, Denis RGP, Boya P, Galluzzi L, Madeo F, Migrenne-Li S, Cruciani-Guglielmacci C, Tavernarakis N, López-Otín C, Magnan C, Kroemer G.

Cell Metab. 2019 Dec 3;30(6):1171. doi: 10.1016/j.cmet.2019.10.011. No abstract available.

PMID:
31801056
3.

Immunosuppression by Mutated Calreticulin Released from Malignant Cells.

Liu P, Zhao L, Loos F, Marty C, Xie W, Martins I, Lachkar S, Qu B, Waeckel-Énée E, Plo I, Vainchenker W, Perez F, Rodriguez D, López-Otin C, van Endert P, Zitvogel L, Kepp O, Kroemer G.

Mol Cell. 2019 Nov 23. pii: S1097-2765(19)30833-0. doi: 10.1016/j.molcel.2019.11.004. [Epub ahead of print]

PMID:
31785928
4.

Immunostimulatory gut bacteria.

Zitvogel L, Kroemer G.

Science. 2019 Nov 29;366(6469):1077-1078. doi: 10.1126/science.aaz7595. No abstract available.

PMID:
31780546
5.

Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation.

Gehrmann U, Burbage M, Zueva E, Goudot C, Esnault C, Ye M, Carpier JM, Burgdorf N, Hoyler T, Suarez G, Joannas L, Heurtebise-Chrétien S, Durand S, Panes R, Bellemare-Pelletier A, Sáez PJ, Aprahamian F, Lefevre D, Adoue V, Zine El Aabidine A, Muhammad Ahmad M, Hivroz C, Joffre O, Cammas F, Kroemer G, Gagnon E, Andrau JC, Amigorena S.

Proc Natl Acad Sci U S A. 2019 Nov 27. pii: 201901639. doi: 10.1073/pnas.1901639116. [Epub ahead of print]

6.

Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients.

Kasikova L, Hensler M, Truxova I, Skapa P, Laco J, Belicova L, Praznovec I, Vosahlikova S, Halaska MJ, Brtnicky T, Rob L, Presl J, Kostun J, Cremer I, Ryska A, Kroemer G, Galluzzi L, Spisek R, Fucikova J.

J Immunother Cancer. 2019 Nov 20;7(1):312. doi: 10.1186/s40425-019-0781-z.

7.

Assessment of annexin A1 release during immunogenic cell death.

Baracco EE, Petrazzuolo A, Kroemer G.

Methods Enzymol. 2019;629:71-79. doi: 10.1016/bs.mie.2019.06.010. Epub 2019 Jul 2.

PMID:
31727257
8.

Quantification of eIF2alpha phosphorylation during immunogenic cell death.

Bezu L, Wu Chuang A, Humeau J, Kroemer G, Kepp O.

Methods Enzymol. 2019;629:53-69. doi: 10.1016/bs.mie.2019.04.010. Epub 2019 Apr 27.

PMID:
31727256
9.

Methods for measuring HMGB1 release during immunogenic cell death.

Zhao L, Liu P, Kepp O, Kroemer G.

Methods Enzymol. 2019;629:177-193. doi: 10.1016/bs.mie.2019.05.001. Epub 2019 May 27.

PMID:
31727240
10.

Quinacrine-mediated detection of intracellular ATP.

Forveille S, Humeau J, Sauvat A, Bezu L, Kroemer G, Kepp O.

Methods Enzymol. 2019;629:103-113. doi: 10.1016/bs.mie.2019.05.050. Epub 2019 Jun 17.

PMID:
31727236
11.

Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina.

Notomi S, Ishihara K, Efstathiou NE, Lee JJ, Hisatomi T, Tachibana T, Konstantinou EK, Ueta T, Murakami Y, Maidana DE, Ikeda Y, Kume S, Terasaki H, Sonoda S, Blanz J, Young L, Sakamoto T, Sonoda KH, Saftig P, Ishibashi T, Miller JW, Kroemer G, Vavvas DG.

Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23724-23734. doi: 10.1073/pnas.1906643116. Epub 2019 Nov 7.

12.

The elusive "hunger protein": an appetite-stimulatory factor that is overabundant in human obesity.

Bravo-San Pedro JM, Sica V, Kroemer G.

Mol Cell Oncol. 2019 Oct 15;6(6):e1667193. doi: 10.1080/23723556.2019.1667193. eCollection 2019.

PMID:
31692883
13.

A discovery platform for the identification of caloric restriction mimetics with broad health-improving effects.

Kepp O, Chen G, Carmona-Gutierrez D, Madeo F, Kroemer G.

Autophagy. 2019 Nov 7:1-2. doi: 10.1080/15548627.2019.1688984. [Epub ahead of print]

PMID:
31690168
14.

BML-265 and Tyrphostin AG1478 Disperse the Golgi Apparatus and Abolish Protein Transport in Human Cells.

Boncompain G, Gareil N, Tessier S, Lescure A, Jones TR, Kepp O, Kroemer G, Del Nery E, Perez F.

Front Cell Dev Biol. 2019 Oct 11;7:232. doi: 10.3389/fcell.2019.00232. eCollection 2019.

15.

Acyl-CoA-binding protein (ACBP): the elusive 'hunger factor' linking autophagy to food intake.

Pedro JMB, Sica V, Madeo F, Kroemer G.

Cell Stress. 2019 Sep 24;3(10):312-318. doi: 10.15698/cst2019.10.200. Review.

16.

A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice.

Lévesque S, Le Naour J, Pietrocola F, Paillet J, Kremer M, Castoldi F, Baracco EE, Wang Y, Vacchelli E, Stoll G, Jolly A, De La Grange P, Zitvogel L, Kroemer G, Pol JG.

Oncoimmunology. 2019 Sep 7;8(11):e1657375. doi: 10.1080/2162402X.2019.1657375. eCollection 2019.

17.

Lurbinectedin synergizes with immune checkpoint blockade to generate anticancer immunity.

Xie W, Forveille S, Iribarren K, Sauvat A, Senovilla L, Wang Y, Humeau J, Perez-Lanzon M, Zhou H, Martínez-Leal JF, Kroemer G, Kepp O.

Oncoimmunology. 2019 Sep 5;8(11):e1656502. doi: 10.1080/2162402X.2019.1656502. eCollection 2019.

PMID:
31646106
18.

Trial watch: dendritic cell vaccination for cancer immunotherapy.

Sprooten J, Ceusters J, Coosemans A, Agostinis P, De Vleeschouwer S, Zitvogel L, Kroemer G, Galluzzi L, Garg AD.

Oncoimmunology. 2019 Jul 18;8(11):e1638212. doi: 10.1080/2162402X.2019.1638212. eCollection 2019. Review.

PMID:
31646087
19.

Suppression of tumor antigen presentation during aneuploid tumor evolution contributes to immune evasion.

Tripathi R, Modur V, Senovilla L, Kroemer G, Komurov K.

Oncoimmunology. 2019 Sep 6;8(11):1657374. doi: 10.1080/2162402X.2019.1657374. eCollection 2019.

20.

Clinical evidence that immunogenic cell death sensitizes to PD-1/PD-L1 blockade.

Kepp O, Zitvogel L, Kroemer G.

Oncoimmunology. 2019 Jul 22;8(10):e1637188. doi: 10.1080/2162402X.2019.1637188. eCollection 2019.

PMID:
31646079
21.

Caloric restriction promotes the stemness and antitumor activity of T lymphocytes.

Pietrocola F, Kroemer G.

Oncoimmunology. 2019 May 16;8(10):e1616153. doi: 10.1080/2162402X.2019.1616153. eCollection 2019.

PMID:
31646069
22.

Effects of interleukin-2 in immunostimulation and immunosuppression.

Pol JG, Caudana P, Paillet J, Piaggio E, Kroemer G.

J Exp Med. 2020 Jan 6;217(1). pii: e20191247. doi: 10.1084/jem.20191247.

PMID:
31611250
23.

3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB.

Chen G, Xie W, Nah J, Sauvat A, Liu P, Pietrocola F, Sica V, Carmona-Gutierrez D, Zimmermann A, Pendl T, Tadic J, Bergmann M, Hofer SJ, Domuz L, Lachkar S, Markaki M, Tavernarakis N, Sadoshima J, Madeo F, Kepp O, Kroemer G.

EMBO Mol Med. 2019 Nov 7;11(11):e10469. doi: 10.15252/emmm.201910469. Epub 2019 Oct 14.

24.

Pseudodiabetes-not a contraindication for metabolic interventions.

Bravo-San Pedro JM, Sica V, Kroemer G.

Cell Death Dis. 2019 Oct 10;10(10):765. doi: 10.1038/s41419-019-2007-1.

25.

Artificial tethering of LC3 or p62 to organelles is not sufficient to trigger autophagy.

Loos F, Xie W, Sica V, Bravo-San Pedro JM, Souquère S, Pierron G, Lachkar S, Sauvat A, Petrazzuolo A, Jimenez AJ, Perez F, Maiuri MC, Kepp O, Kroemer G.

Cell Death Dis. 2019 Oct 10;10(10):771. doi: 10.1038/s41419-019-2011-5.

26.

Oncolysis without viruses - inducing systemic anticancer immune responses with local therapies.

Kepp O, Marabelle A, Zitvogel L, Kroemer G.

Nat Rev Clin Oncol. 2019 Oct 8. doi: 10.1038/s41571-019-0272-7. [Epub ahead of print] Review.

PMID:
31595049
27.

HIV-1 Envelope Overcomes NLRP3-Mediated Inhibition of F-Actin Polymerization for Viral Entry.

Paoletti A, Allouch A, Caillet M, Saïdi H, Subra F, Nardacci R, Wu Q, Muradova Z, Voisin L, Raza SQ, Law F, Thoreau M, Dakhli H, Delelis O, Poirier-Beaudouin B, Dereuddre-Bosquet N, Le Grand R, Lambotte O, Saez-Cirion A, Pancino G, Ojcius DM, Solary E, Deutsch E, Piacentini M, Gougeon ML, Kroemer G, Perfettini JL.

Cell Rep. 2019 Sep 24;28(13):3381-3394.e7. doi: 10.1016/j.celrep.2019.02.095.

28.

Leptin-Producing Oncolytic Virus Makes Tumor-Infiltrating T Cells Fit, Not Fat.

Kroemer G, Zitvogel L.

Immunity. 2019 Sep 17;51(3):423-425. doi: 10.1016/j.immuni.2019.08.010.

PMID:
31533054
29.

Stress-glucocorticoid-TSC22D3 axis compromises therapy-induced antitumor immunity.

Yang H, Xia L, Chen J, Zhang S, Martin V, Li Q, Lin S, Chen J, Calmette J, Lu M, Fu L, Yang J, Pan Z, Yu K, He J, Morand E, Schlecht-Louf G, Krzysiek R, Zitvogel L, Kang B, Zhang Z, Leader A, Zhou P, Lanfumey L, Shi M, Kroemer G, Ma Y.

Nat Med. 2019 Sep;25(9):1428-1441. doi: 10.1038/s41591-019-0566-4. Epub 2019 Sep 9.

PMID:
31501614
30.

Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade.

Jacquelot N, Yamazaki T, Roberti MP, Duong CPM, Andrews MC, Verlingue L, Ferrere G, Becharef S, Vétizou M, Daillère R, Messaoudene M, Enot DP, Stoll G, Ugel S, Marigo I, Foong Ngiow S, Marabelle A, Prevost-Blondel A, Gaudreau PO, Gopalakrishnan V, Eggermont AM, Opolon P, Klein C, Madonna G, Ascierto PA, Sucker A, Schadendorf D, Smyth MJ, Soria JC, Kroemer G, Bronte V, Wargo J, Zitvogel L.

Cell Res. 2019 Oct;29(10):846-861. doi: 10.1038/s41422-019-0224-x. Epub 2019 Sep 3.

PMID:
31481761
31.

Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans.

Stekovic S, Hofer SJ, Tripolt N, Aon MA, Royer P, Pein L, Stadler JT, Pendl T, Prietl B, Url J, Schroeder S, Tadic J, Eisenberg T, Magnes C, Stumpe M, Zuegner E, Bordag N, Riedl R, Schmidt A, Kolesnik E, Verheyen N, Springer A, Madl T, Sinner F, de Cabo R, Kroemer G, Obermayer-Pietsch B, Dengjel J, Sourij H, Pieber TR, Madeo F.

Cell Metab. 2019 Sep 3;30(3):462-476.e5. doi: 10.1016/j.cmet.2019.07.016. Epub 2019 Aug 27.

PMID:
31471173
32.

Cell-autonomous, paracrine and neuroendocrine feedback regulation of autophagy by DBI/ACBP (diazepam binding inhibitor, acyl-CoA binding protein): the obesity factor.

Bravo-San Pedro JM, Sica V, Martins I, Anagnostopoulos G, Maiuri C, Kroemer G.

Autophagy. 2019 Nov;15(11):2036-2038. doi: 10.1080/15548627.2019.1662585. Epub 2019 Sep 5.

PMID:
31470770
33.

A strategy for poisoning cancer cell metabolism: Inhibition of oxidative phosphorylation coupled to anaplerotic saturation.

Sica V, Bravo-San Pedro JM, Kroemer G.

Int Rev Cell Mol Biol. 2019;347:27-37. doi: 10.1016/bs.ircmb.2019.07.002. Epub 2019 Jul 29.

PMID:
31451215
34.

Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity.

Bravo-San Pedro JM, Sica V, Martins I, Pol J, Loos F, Maiuri MC, Durand S, Bossut N, Aprahamian F, Anagnostopoulos G, Niso-Santano M, Aranda F, Ramírez-Pardo I, Lallement J, Denom J, Boedec E, Gorwood P, Ramoz N, Clément K, Pelloux V, Rohia A, Pattou F, Raverdy V, Caiazzo R, Denis RGP, Boya P, Galluzzi L, Madeo F, Migrenne-Li S, Cruciani-Guglielmacci C, Tavernarakis N, López-Otín C, Magnan C, Kroemer G.

Cell Metab. 2019 Oct 1;30(4):754-767.e9. doi: 10.1016/j.cmet.2019.07.010. Epub 2019 Aug 15. Erratum in: Cell Metab. 2019 Dec 3;30(6):1171.

PMID:
31422903
35.

A fluorescent biosensor-based platform for the discovery of immunogenic cancer cell death inducers.

Kepp O, Sauvat A, Leduc M, Forveille S, Liu P, Zhao L, Bezu L, Xie W, Zitvogel L, Kroemer G.

Oncoimmunology. 2019 Apr 26;8(8):1606665. doi: 10.1080/2162402X.2019.1606665. eCollection 2019. Review.

PMID:
31413915
36.

Oxidative phosphorylation as a potential therapeutic target for cancer therapy.

Sica V, Bravo-San Pedro JM, Stoll G, Kroemer G.

Int J Cancer. 2020 Jan 1;146(1):10-17. doi: 10.1002/ijc.32616. Epub 2019 Sep 11. Review.

PMID:
31396957
37.

Optimising efficacy and reducing toxicity of anticancer radioimmunotherapy.

Deutsch E, Chargari C, Galluzzi L, Kroemer G.

Lancet Oncol. 2019 Aug;20(8):e452-e463. doi: 10.1016/S1470-2045(19)30171-8. Epub 2019 Jul 29. Review.

PMID:
31364597
38.

Clockophagy is a novel selective autophagy process favoring ferroptosis.

Yang M, Chen P, Liu J, Zhu S, Kroemer G, Klionsky DJ, Lotze MT, Zeh HJ, Kang R, Tang D.

Sci Adv. 2019 Jul 24;5(7):eaaw2238. doi: 10.1126/sciadv.aaw2238. eCollection 2019 Jul.

39.

The metabolomic signature of extreme longevity: naked mole rats versus mice.

Viltard M, Durand S, Pérez-Lanzón M, Aprahamian F, Lefevre D, Leroy C, Madeo F, Kroemer G, Friedlander G.

Aging (Albany NY). 2019 Jul 24;11(14):4783-4800. doi: 10.18632/aging.102116.

40.

Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice.

Bárcena C, Valdés-Mas R, Mayoral P, Garabaya C, Durand S, Rodríguez F, Fernández-García MT, Salazar N, Nogacka AM, Garatachea N, Bossut N, Aprahamian F, Lucia A, Kroemer G, Freije JMP, Quirós PM, López-Otín C.

Nat Med. 2019 Aug;25(8):1234-1242. doi: 10.1038/s41591-019-0504-5. Epub 2019 Jul 22.

PMID:
31332389
41.

The Molecular Hallmarks of the Serrated Pathway in Colorectal Cancer.

De Palma FDE, D'Argenio V, Pol J, Kroemer G, Maiuri MC, Salvatore F.

Cancers (Basel). 2019 Jul 20;11(7). pii: E1017. doi: 10.3390/cancers11071017. Review.

42.

Cystic fibrosis transmembrane conductance regulator (CFTR) and autophagy: hereditary defects in cystic fibrosis versus gluten-mediated inhibition in celiac disease.

Maiuri L, Raia V, Piacentini M, Tosco A, Villella VR, Kroemer G.

Oncotarget. 2019 Jul 8;10(43):4492-4500. doi: 10.18632/oncotarget.27037. eCollection 2019 Jul 8. Review.

43.

Macrophages and Metabolism in the Tumor Microenvironment.

Vitale I, Manic G, Coussens LM, Kroemer G, Galluzzi L.

Cell Metab. 2019 Jul 2;30(1):36-50. doi: 10.1016/j.cmet.2019.06.001. Review.

PMID:
31269428
44.

The negative impact of antibiotics on outcomes in cancer patients treated with immunotherapy: a new independent prognostic factor?

Elkrief A, Derosa L, Kroemer G, Zitvogel L, Routy B.

Ann Oncol. 2019 Oct 1;30(10):1572-1579. doi: 10.1093/annonc/mdz206.

PMID:
31268133
45.

4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects.

Zimmermann A, Kainz K, Hofer SJ, Bauer MA, Schroeder S, Dengjel J, Pietrocola F, Kepp O, Ruckenstuhl C, Eisenberg T, Sigrist SJ, Madeo F, Carmona-Gutierrez D, Kroemer G.

Autophagy. 2019 Sep;15(9):1662-1664. doi: 10.1080/15548627.2019.1632623. Epub 2019 Jun 28.

46.

Autophagy, Inflammation, and Metabolism (AIM) Center in its second year.

Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Liu M, Hall P, Sklar LA, Allers L, Mariscal L, Garcia SA, Weaver J, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, Eskelinen EL, Fourie B, Gozuacik D, Hong W, Jo EK, Johansen T, Juhász G, Kimchi A, Ktistakis N, Kroemer G, Mizushima N, Münz C, Reggiori F, Rubinsztein D, Ryan K, Schroder K, Shen HM, Simonsen A, Tooze SA, Vaccaro M, Yoshimori T, Yu L, Zhang H, Klionsky DJ.

Autophagy. 2019 Oct;15(10):1829-1833. doi: 10.1080/15548627.2019.1634444. Epub 2019 Jul 15.

PMID:
31234750
47.

Autophagy represses hepatic carcinogenesis.

Paillet J, Kroemer G.

Mol Cell Oncol. 2019 May 13;6(4):1573080. doi: 10.1080/23723556.2019.1573080. eCollection 2019. Review.

PMID:
31211229
48.

Publisher Correction: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.

Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, Sagredo A, Bustos G, Hazari Y, Ramos-Fernández E, Sassano ML, Pihán P, van Vliet AR, González-Quiroz M, Torres AK, Tapia-Rojas C, Kerkhofs M, Vicente R, Kaufman RJ, Inestrosa NC, Gonzalez-Billault C, Wiseman RL, Agostinis P, Bultynck G, Court FA, Kroemer G, Cárdenas JC, Hetz C.

Nat Cell Biol. 2019 Jul;21(7):913. doi: 10.1038/s41556-019-0355-9.

PMID:
31201389
49.

A transcriptional signature associated with non-Hodgkin lymphoma in the blood of patients with Q fever.

Melenotte C, Mezouar S, Ben Amara A, Benatti S, Chiaroni J, Devaux C, Costello R, Kroemer G, Mege JL, Raoult D.

PLoS One. 2019 Jun 10;14(6):e0217542. doi: 10.1371/journal.pone.0217542. eCollection 2019.

50.

α-Ketoglutarate inhibits autophagy.

Baracco EE, Castoldi F, Durand S, Enot DP, Tadic J, Kainz K, Madeo F, Chery A, Izzo V, Maiuri MC, Pietrocola F, Kroemer G.

Aging (Albany NY). 2019 Jun 7;11(11):3418-3431. doi: 10.18632/aging.102001.

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