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Items: 1 to 50 of 1176

1.

Failure of immunosurveillance accelerates aging.

Perez-Lanzon M, Zitvogel L, Kroemer G.

Oncoimmunology. 2019 Feb 9;8(4):e1575117. doi: 10.1080/2162402X.2019.1575117. eCollection 2019.

PMID:
30906669
2.

The gliadin-CFTR connection: new perspectives for the treatment of celiac disease.

Maiuri L, Villella VR, Raia V, Kroemer G.

Ital J Pediatr. 2019 Mar 21;45(1):40. doi: 10.1186/s13052-019-0627-9.

3.

Ferroptosis is a type of autophagy-dependent cell death.

Zhou B, Liu J, Kang R, Klionsky DJ, Kroemer G, Tang D.

Semin Cancer Biol. 2019 Mar 14. pii: S1044-579X(19)30006-9. doi: 10.1016/j.semcancer.2019.03.002. [Epub ahead of print] Review.

PMID:
30880243
4.

Autophagy suppresses the pathogenic immune response to dietary antigens in cystic fibrosis.

Villella VR, Esposito S, Ferrari E, Monzani R, Tosco A, Rossin F, Castaldo A, Silano M, Marseglia GL, Romani L, Barlev NA, Piacentini M, Raia V, Kroemer G, Maiuri L.

Cell Death Dis. 2019 Mar 15;10(4):258. doi: 10.1038/s41419-019-1500-x.

5.

Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux.

Zhang S, Wang Y, Xie W, Howe ENW, Busschaert N, Sauvat A, Leduc M, Gomes-da-Silva LC, Chen G, Martins I, Deng X, Maiuri L, Kepp O, Soussi T, Gale PA, Zamzami N, Kroemer G.

Cell Death Dis. 2019 Mar 11;10(3):242. doi: 10.1038/s41419-019-1474-8.

6.

ColocalizR: An open-source application for cell-based high-throughput colocalization analysis.

Sauvat A, Leduc M, Müller K, Kepp O, Kroemer G.

Comput Biol Med. 2019 Mar 2;107:227-234. doi: 10.1016/j.compbiomed.2019.02.024. [Epub ahead of print]

PMID:
30852249
7.

Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential.

Madeo F, Carmona-Gutierrez D, Hofer SJ, Kroemer G.

Cell Metab. 2019 Mar 5;29(3):592-610. doi: 10.1016/j.cmet.2019.01.018. Review.

PMID:
30840912
8.

Luigi Maiuri: un Grande Uomo - a Great Spirit.

Piacentini M, Kroemer G.

Cell Death Dis. 2019 Mar 1;10(3):209. doi: 10.1038/s41419-019-1466-8. No abstract available.

9.

Etiological involvement of CFTR in apparently unrelated human diseases.

Galluzzi L, Kroemer G.

Mol Cell Oncol. 2018 Dec 27;6(1):1558874. doi: 10.1080/23723556.2018.1558874. eCollection 2019. No abstract available.

PMID:
30788425
10.

The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species.

Carmona-Gutierrez D, Zimmermann A, Kainz K, Pietrocola F, Chen G, Maglioni S, Schiavi A, Nah J, Mertel S, Beuschel CB, Castoldi F, Sica V, Trausinger G, Raml R, Sommer C, Schroeder S, Hofer SJ, Bauer MA, Pendl T, Tadic J, Dammbrueck C, Hu Z, Ruckenstuhl C, Eisenberg T, Durand S, Bossut N, Aprahamian F, Abdellatif M, Sedej S, Enot DP, Wolinski H, Dengjel J, Kepp O, Magnes C, Sinner F, Pieber TR, Sadoshima J, Ventura N, Sigrist SJ, Kroemer G, Madeo F.

Nat Commun. 2019 Feb 19;10(1):651. doi: 10.1038/s41467-019-08555-w.

11.

Personalization of therapies in rare diseases: a translational approach for the treatment of cystic fibrosis.

Villella VR, Tosco A, Esposito S, Ferrari E, Bona G, Kroemer G, Raia V, Maiuri L.

Minerva Pediatr. 2019 Feb 13. doi: 10.23736/S0026-4946.19.05511-7. [Epub ahead of print]

PMID:
30761822
12.

Defective proteostasis in celiac disease as a new therapeutic target.

Maiuri L, Villella VR, Piacentini M, Raia V, Kroemer G.

Cell Death Dis. 2019 Feb 8;10(2):114. doi: 10.1038/s41419-019-1392-9. Review.

13.

Therapeutic modulation of autophagy: which disease comes first?

Maiuri MC, Kroemer G.

Cell Death Differ. 2019 Mar;26(4):680-689. doi: 10.1038/s41418-019-0290-0. Epub 2019 Feb 6. Review.

PMID:
30728461
14.

Anticancer effects of anti-CD47 immunotherapy in vivo.

Iribarren K, Buque A, Mondragon L, Xie W, Lévesque S, Pol J, Zitvogel L, Kepp O, Kroemer G.

Oncoimmunology. 2018 Dec 11;8(3):1550619. doi: 10.1080/2162402X.2018.1550619. eCollection 2019.

PMID:
30723582
15.

Biological Functions of Autophagy Genes: A Disease Perspective.

Levine B, Kroemer G.

Cell. 2019 Jan 10;176(1-2):11-42. doi: 10.1016/j.cell.2018.09.048. Review.

PMID:
30633901
16.

Cardioprotective effects of autophagy induction in sepsis.

Abdellatif M, Sedej S, Madeo F, Kroemer G.

Ann Transl Med. 2018 Nov;6(Suppl 1):S61. doi: 10.21037/atm.2018.10.23. No abstract available.

17.

Lack of the brain-specific isoform of apoptosis-inducing factor aggravates cerebral damage in a model of neonatal hypoxia-ischemia.

Rodriguez J, Zhang Y, Li T, Xie C, Sun Y, Xu Y, Zhou K, Huo K, Wang Y, Wang X, Andersson D, Ståhlberg A, Xing Q, Mallard C, Hagberg H, Modjtahedi N, Kroemer G, Blomgren K, Zhu C.

Cell Death Dis. 2018 Dec 18;10(1):3. doi: 10.1038/s41419-018-1250-1.

18.

Reply to Gostner and Fuchs.

Pechlaner R, Madeo F, Eisenberg T, Kroemer G, Tilg H, Willeit J, Kiechl S.

Am J Clin Nutr. 2019 Jan 1;109(1):218-219. doi: 10.1093/ajcn/nqy222. No abstract available.

PMID:
30576412
19.

Autophagy delays progression of the two most frequent human monogenetic lethal diseases: cystic fibrosis and Wilson disease.

Maiuri L, Kroemer G.

Aging (Albany NY). 2018 Dec 19;10(12):3657-3661. doi: 10.18632/aging.101736.

20.

Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells.

Dajon M, Iribarren K, Petitprez F, Marmier S, Lupo A, Gillard M, Ouakrim H, Victor N, Vincenzo DB, Joubert PE, Kepp O, Kroemer G, Alifano M, Damotte D, Cremer I.

Oncoimmunology. 2018 Oct 11;8(1):e1505174. doi: 10.1080/2162402X.2018.1505174. eCollection 2019.

21.

Systemic autophagy in the therapeutic response to anthracycline-based chemotherapy.

Castoldi F, Vacchelli E, Zitvogel L, Maiuri MC, Pietrocola F, Kroemer G.

Oncoimmunology. 2018 Oct 1;8(1):e1498285. doi: 10.1080/2162402X.2018.1498285. eCollection 2019.

22.

Cisplatin resistance coupled to enhanced sensitivity to metabolic interventions.

Castedo M, Obrist F, Kroemer G.

Mol Cell Oncol. 2018 Oct 10;5(6):e1526004. doi: 10.1080/23723556.2018.1526004. eCollection 2018.

PMID:
30525097
23.

Potent immunosuppressive effects of the oncometabolite R-2-hydroxyglutarate.

Galluzzi L, Kroemer G.

Oncoimmunology. 2018 Oct 16;7(12):e1528815. doi: 10.1080/2162402X.2018.1528815. eCollection 2018.

PMID:
30524910
24.

Trial Watch: Toll-like receptor agonists in cancer immunotherapy.

Smith M, García-Martínez E, Pitter MR, Fucikova J, Spisek R, Zitvogel L, Kroemer G, Galluzzi L.

Oncoimmunology. 2018 Oct 11;7(12):e1526250. doi: 10.1080/2162402X.2018.1526250. eCollection 2018. Review.

PMID:
30524908
25.

Trial watch: Peptide-based vaccines in anticancer therapy.

Bezu L, Kepp O, Cerrato G, Pol J, Fucikova J, Spisek R, Zitvogel L, Kroemer G, Galluzzi L.

Oncoimmunology. 2018 Sep 6;7(12):e1511506. doi: 10.1080/2162402X.2018.1511506. eCollection 2018. Review.

26.

Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors.

G Pol J, Lévesque S, Workenhe ST, Gujar S, Le Boeuf F, R Clements D, Fahrner JE, Fend L, C Bell J, L Mossman K, Fucikova J, Spisek R, Zitvogel L, Kroemer G, Galluzzi L.

Oncoimmunology. 2018 Aug 27;7(12):e1503032. doi: 10.1080/2162402X.2018.1503032. eCollection 2018. Review.

PMID:
30524901
27.

Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca2+ levels and tumor growth.

Marchi S, Corricelli M, Branchini A, Vitto VAM, Missiroli S, Morciano G, Perrone M, Ferrarese M, Giorgi C, Pinotti M, Galluzzi L, Kroemer G, Pinton P.

EMBO J. 2019 Jan 15;38(2). pii: e99435. doi: 10.15252/embj.201899435. Epub 2018 Nov 30.

PMID:
30504268
28.

Cancer-Induced Endoplasmic Reticulum Stress in T Cells Subverts Immunosurveillance.

López-Soto A, Kroemer G.

Cell Metab. 2018 Dec 4;28(6):803-805. doi: 10.1016/j.cmet.2018.11.003.

PMID:
30517892
29.

A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease.

Villella VR, Venerando A, Cozza G, Esposito S, Ferrari E, Monzani R, Spinella MC, Oikonomou V, Renga G, Tosco A, Rossin F, Guido S, Silano M, Garaci E, Chao YK, Grimm C, Luciani A, Romani L, Piacentini M, Raia V, Kroemer G, Maiuri L.

EMBO J. 2019 Jan 15;38(2). pii: e100101. doi: 10.15252/embj.2018100101. Epub 2018 Nov 29.

30.

Gold Standard Assessment of Immunogenic Cell Death in Oncological Mouse Models.

Humeau J, Lévesque S, Kroemer G, Pol JG.

Methods Mol Biol. 2019;1884:297-315. doi: 10.1007/978-1-4939-8885-3_21.

PMID:
30465212
31.

Activation of Autophagy, Observed in Liver Tissues From Patients With Wilson Disease and From ATP7B-Deficient Animals, Protects Hepatocytes From Copper-Induced Apoptosis.

Polishchuk EV, Merolla A, Lichtmannegger J, Romano A, Indrieri A, Ilyechova EY, Concilli M, De Cegli R, Crispino R, Mariniello M, Petruzzelli R, Ranucci G, Iorio R, Pietrocola F, Einer C, Borchard S, Zibert A, Schmidt HH, Di Schiavi E, Puchkova LV, Franco B, Kroemer G, Zischka H, Polishchuk RS.

Gastroenterology. 2019 Mar;156(4):1173-1189.e5. doi: 10.1053/j.gastro.2018.11.032. Epub 2018 Nov 17.

PMID:
30452922
32.

Chlamydia trachomatis fails to protect its growth niche against pro-apoptotic insults.

Sixt BS, Núñez-Otero C, Kepp O, Valdivia RH, Kroemer G.

Cell Death Differ. 2018 Oct 30. doi: 10.1038/s41418-018-0224-2. [Epub ahead of print]

PMID:
30375511
33.

Autophagy in Cardiovascular Aging.

Abdellatif M, Sedej S, Carmona-Gutierrez D, Madeo F, Kroemer G.

Circ Res. 2018 Sep 14;123(7):803-824. doi: 10.1161/CIRCRESAHA.118.312208.

PMID:
30355077
34.

Spermidine reduces cancer-related mortality in humans.

Pietrocola F, Castoldi F, Kepp O, Carmona-Gutierrez D, Madeo F, Kroemer G.

Autophagy. 2018 Oct 24:1-4. doi: 10.1080/15548627.2018.1539592. [Epub ahead of print]

PMID:
30354939
35.

Oncolysis with DTT-205 and DTT-304 generates immunological memory in cured animals.

Zhou H, Mondragón L, Xie W, Mauseth B, Leduc M, Sauvat A, Gomes-da-Silva LC, Forveille S, Iribarren K, Souquere S, Bezu L, Liu P, Zhao L, Zitvogel L, Sveinbjørnsson B, Eksteen JJ, Rekdal Ø, Kepp O, Kroemer G.

Cell Death Dis. 2018 Oct 23;9(11):1086. doi: 10.1038/s41419-018-1127-3.

36.

Recruitment of LC3 to damaged Golgi apparatus.

Gomes-da-Silva LC, Jimenez AJ, Sauvat A, Xie W, Souquere S, Divoux S, Storch M, Sveinbjørnsson B, Rekdal Ø, Arnaut LG, Kepp O, Kroemer G, Perez F.

Cell Death Differ. 2018 Oct 22. doi: 10.1038/s41418-018-0221-5. [Epub ahead of print]

PMID:
30349077
37.

Carbotoxicity-Noxious Effects of Carbohydrates.

Kroemer G, López-Otín C, Madeo F, de Cabo R.

Cell. 2018 Oct 18;175(3):605-614. doi: 10.1016/j.cell.2018.07.044. Review.

PMID:
30340032
38.

The intimate relationship between gut microbiota and cancer immunotherapy.

Elkrief A, Derosa L, Zitvogel L, Kroemer G, Routy B.

Gut Microbes. 2018 Oct 19:1-5. doi: 10.1080/19490976.2018.1527167. [Epub ahead of print]

PMID:
30339501
39.

Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?

Madeo F, Bauer MA, Carmona-Gutierrez D, Kroemer G.

Autophagy. 2019 Jan;15(1):165-168. doi: 10.1080/15548627.2018.1530929. Epub 2018 Oct 11.

40.

Linking cellular stress responses to systemic homeostasis.

Galluzzi L, Yamazaki T, Kroemer G.

Nat Rev Mol Cell Biol. 2018 Nov;19(11):731-745. doi: 10.1038/s41580-018-0068-0. Review.

PMID:
30305710
41.

Methionine restriction for improving progeria: another autophagy-inducing anti-aging strategy?

Bárcena C, López-Otín C, Kroemer G.

Autophagy. 2019 Mar;15(3):558-559. doi: 10.1080/15548627.2018.1533059. Epub 2018 Oct 18.

PMID:
30304972
42.

Identification of pharmacological inhibitors of conventional protein secretion.

Zhao L, Liu P, Boncompain G, Loos F, Lachkar S, Bezu L, Chen G, Zhou H, Perez F, Kepp O, Kroemer G.

Sci Rep. 2018 Oct 8;8(1):14966. doi: 10.1038/s41598-018-33378-y.

43.

Impact of chemotactic factors and receptors on the cancer immune infiltrate: a bioinformatics study revealing homogeneity and heterogeneity among patient cohorts.

Stoll G, Pol J, Soumelis V, Zitvogel L, Kroemer G.

Oncoimmunology. 2018 Aug 6;7(10):e1484980. doi: 10.1080/2162402X.2018.1484980. eCollection 2018.

44.

The hallmarks of successful anticancer immunotherapy.

Galluzzi L, Chan TA, Kroemer G, Wolchok JD, López-Soto A.

Sci Transl Med. 2018 Sep 19;10(459). pii: eaat7807. doi: 10.1126/scitranslmed.aat7807. Review.

PMID:
30232229
45.

TumGrowth: An open-access web tool for the statistical analysis of tumor growth curves.

Enot DP, Vacchelli E, Jacquelot N, Zitvogel L, Kroemer G.

Oncoimmunology. 2018 Aug 1;7(9):e1462431. doi: 10.1080/2162402X.2018.1462431. eCollection 2018.

46.

Immune effectors responsible for the elimination of hyperploid cancer cells.

Aranda F, Chaba K, Bloy N, Garcia P, Bordenave C, Martins I, Stoll G, Tesniere A, Kroemer G, Senovilla L.

Oncoimmunology. 2018 May 21;7(8):e1463947. doi: 10.1080/2162402X.2018.1463947. eCollection 2018.

PMID:
30221060
47.

Heating it up: Oncolytic viruses make tumors 'hot' and suitable for checkpoint blockade immunotherapies.

Gujar S, Pol JG, Kroemer G.

Oncoimmunology. 2018 Mar 13;7(8):e1442169. doi: 10.1080/2162402X.2018.1442169. eCollection 2018.

48.

Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles.

Bonora M, Wieckowski MR, Sinclair DA, Kroemer G, Pinton P, Galluzzi L.

Nat Rev Cardiol. 2019 Jan;16(1):33-55. doi: 10.1038/s41569-018-0074-0. Review.

PMID:
30177752
49.

Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism.

Bárcena C, Quirós PM, Durand S, Mayoral P, Rodríguez F, Caravia XM, Mariño G, Garabaya C, Fernández-García MT, Kroemer G, Freije JMP, López-Otín C.

Cell Rep. 2018 Aug 28;24(9):2392-2403. doi: 10.1016/j.celrep.2018.07.089.

50.

MDM2-TP53 Crossregulation: An Underestimated Target to Promote Loss of TP53 Function and Cell Survival.

Soussi T, Kroemer G.

Trends Cancer. 2018 Sep;4(9):602-605. doi: 10.1016/j.trecan.2018.07.001. Epub 2018 Jul 21.

PMID:
30149877

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