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Items: 1 to 50 of 1264

1.

Autophagy induction by thiostrepton improves the efficacy of immunogenic chemotherapy.

Wang Y, Xie W, Humeau J, Chen G, Liu P, Pol J, Zhang Z, Kepp O, Kroemer G.

J Immunother Cancer. 2020 Mar;8(1). pii: e000462. doi: 10.1136/jitc-2019-000462.

2.

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death.

Galluzzi L, Vitale I, Warren S, Adjemian S, Agostinis P, Martinez AB, Chan TA, Coukos G, Demaria S, Deutsch E, Draganov D, Edelson RL, Formenti SC, Fucikova J, Gabriele L, Gaipl US, Gameiro SR, Garg AD, Golden E, Han J, Harrington KJ, Hemminki A, Hodge JW, Hossain DMS, Illidge T, Karin M, Kaufman HL, Kepp O, Kroemer G, Lasarte JJ, Loi S, Lotze MT, Manic G, Merghoub T, Melcher AA, Mossman KL, Prosper F, Rekdal Ø, Rescigno M, Riganti C, Sistigu A, Smyth MJ, Spisek R, Stagg J, Strauss BE, Tang D, Tatsuno K, van Gool SW, Vandenabeele P, Yamazaki T, Zamarin D, Zitvogel L, Cesano A, Marincola FM.

J Immunother Cancer. 2020 Mar;8(1). pii: e000337. doi: 10.1136/jitc-2019-000337. Review.

3.

Autophagy-Dependent Ferroptosis: Machinery and Regulation.

Liu J, Kuang F, Kroemer G, Klionsky DJ, Kang R, Tang D.

Cell Chem Biol. 2020 Mar 3. pii: S2451-9456(20)30069-6. doi: 10.1016/j.chembiol.2020.02.005. [Epub ahead of print] Review.

PMID:
32160513
4.

Antibody-mediated neutralization of ACBP/DBI has anorexigenic and lipolytic effects.

Sica V, Martins I, Motiño O, Bravo-San Pedro JM, Kroemer G.

Adipocyte. 2020 Dec;9(1):116-119. doi: 10.1080/21623945.2020.1736734.

PMID:
32157940
5.

TMEM173 Drives Lethal Coagulation in Sepsis.

Zhang H, Zeng L, Xie M, Liu J, Zhou B, Wu R, Cao L, Kroemer G, Wang H, Billiar TR, Zeh HJ, Kang R, Jiang J, Yu Y, Tang D.

Cell Host Microbe. 2020 Feb 28. pii: S1931-3128(20)30112-8. doi: 10.1016/j.chom.2020.02.004. [Epub ahead of print]

PMID:
32142632
6.

Endoplasmic reticulum stress in the cellular release of damage-associated molecular patterns.

Wu Chuang A, Kepp O, Kroemer G, Bezu L.

Int Rev Cell Mol Biol. 2020;350:1-28. doi: 10.1016/bs.ircmb.2019.11.006. Epub 2019 Dec 4.

PMID:
32138898
7.

A novel platinum-based chemotherapeutic inducing immunogenic cell death.

Kepp O, Kroemer G.

Oncoimmunology. 2020 Feb 15;9(1):1729022. doi: 10.1080/2162402X.2020.1729022. eCollection 2020. No abstract available.

8.

ACBP is an appetite stimulator across phylogenetic barriers.

Madeo F, Tavernarakis N, Pedro JMB, Kroemer G.

Cell Stress. 2020 Jan 20;4(2):27-29. doi: 10.15698/cst2020.02.211. No abstract available.

9.

Secreted calreticulin mutants subvert anticancer immunosurveillance.

Liu P, Zhao L, Kroemer G, Kepp O.

Oncoimmunology. 2019 Dec 28;9(1):1708126. doi: 10.1080/2162402X.2019.1708126. eCollection 2020.

10.

Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology.

Vanmeerbeek I, Sprooten J, De Ruysscher D, Tejpar S, Vandenberghe P, Fucikova J, Spisek R, Zitvogel L, Kroemer G, Galluzzi L, Garg AD.

Oncoimmunology. 2020 Jan 9;9(1):1703449. doi: 10.1080/2162402X.2019.1703449. eCollection 2020. Review.

11.

Comedications influence immune infiltration and pathological response to neoadjuvant chemotherapy in breast cancer.

Hamy AS, Derosa L, Valdelièvre C, Yonekura S, Opolon P, Priour M, Guerin J, Pierga JY, Asselain B, De Croze D, Pinheiro A, Lae M, Talagrand LS, Laas E, Darrigues L, Grandal B, Marangoni E, Montaudon E, Kroemer G, Zitvogel L, Reyal F.

Oncoimmunology. 2019 Nov 14;9(1):1677427. doi: 10.1080/2162402X.2019.1677427. eCollection 2020.

12.

Endogenous and exogenous glucocorticoids abolish the efficacy of immune-dependent cancer therapies.

Ma Y, Yang H, Kroemer G.

Oncoimmunology. 2019 Oct 11;9(1):1673635. doi: 10.1080/2162402X.2019.1673635. eCollection 2020.

13.

Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice.

Li T, Li K, Zhang S, Wang Y, Xu Y, Cronin SJF, Sun Y, Zhang Y, Xie C, Rodriguez J, Zhou K, Hagberg H, Mallard C, Wang X, Penninger JM, Kroemer G, Blomgren K, Zhu C.

Cell Death Dis. 2020 Jan 30;11(1):77. doi: 10.1038/s41419-020-2280-z.

14.

Quantitative determination of phagocytosis by bone marrow-derived dendritic cells via imaging flow cytometry.

Cerrato G, Liu P, Martins I, Kepp O, Kroemer G.

Methods Enzymol. 2020;632:27-37. doi: 10.1016/bs.mie.2019.07.021. Epub 2019 Aug 2.

PMID:
32000900
15.

Side-by-side comparison of flow cytometry and immunohistochemistry for detection of calreticulin exposure in the course of immunogenic cell death.

Kasikova L, Truxova I, Cremer I, Sautes-Fridman C, Kepp O, Kroemer G, Spisek R, Fucikova J.

Methods Enzymol. 2020;632:15-25. doi: 10.1016/bs.mie.2019.05.025. Epub 2019 Jul 8.

PMID:
32000894
16.

Quantitation of calreticulin exposure associated with immunogenic cell death.

Liu P, Zhao L, Kepp O, Kroemer G.

Methods Enzymol. 2020;632:1-13. doi: 10.1016/bs.mie.2019.05.011. Epub 2019 Jun 3.

PMID:
32000891
17.

Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein.

Dai E, Han L, Liu J, Xie Y, Kroemer G, Klionsky DJ, Zeh HJ, Kang R, Wang J, Tang D.

Autophagy. 2020 Jan 16:1-15. doi: 10.1080/15548627.2020.1714209. [Epub ahead of print]

PMID:
31920150
18.

Acyl-CoA-binding protein (ACBP): a phylogenetically conserved appetite stimulator.

Charmpilas N, Ruckenstuhl C, Sica V, Büttner S, Habernig L, Dichtinger S, Madeo F, Tavernarakis N, Bravo-San Pedro JM, Kroemer G.

Cell Death Dis. 2020 Jan 6;11(1):7. doi: 10.1038/s41419-019-2205-x.

19.

Immune contexture of cholangiocarcinoma.

Paillet J, Kroemer G, Pol JG.

Curr Opin Gastroenterol. 2020 Mar;36(2):70-76. doi: 10.1097/MOG.0000000000000613.

PMID:
31895228
20.

Autophagy in hepatic adaptation to stress.

Hazari Y, Bravo-San Pedro JM, Hetz C, Galluzzi L, Kroemer G.

J Hepatol. 2020 Jan;72(1):183-196. doi: 10.1016/j.jhep.2019.08.026. Review.

PMID:
31849347
21.

Immunological Effects of Epigenetic Modifiers.

Bezu L, Chuang AW, Liu P, Kroemer G, Kepp O.

Cancers (Basel). 2019 Dec 1;11(12). pii: E1911. doi: 10.3390/cancers11121911. Review.

22.

Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity.

Bravo-San Pedro JM, Sica V, Martins I, Pol J, Loos F, Maiuri MC, Durand S, Bossut N, Aprahamian F, Anagnostopoulos G, Niso-Santano M, Aranda F, Ramírez-Pardo I, Lallement J, Denom J, Boedec E, Gorwood P, Ramoz N, Clément K, Pelloux V, Rohia A, Pattou F, Raverdy V, Caiazzo R, Denis RGP, Boya P, Galluzzi L, Madeo F, Migrenne-Li S, Cruciani-Guglielmacci C, Tavernarakis N, López-Otín C, Magnan C, Kroemer G.

Cell Metab. 2019 Dec 3;30(6):1171. doi: 10.1016/j.cmet.2019.10.011. No abstract available.

PMID:
31801056
23.

Immunosuppression by Mutated Calreticulin Released from Malignant Cells.

Liu P, Zhao L, Loos F, Marty C, Xie W, Martins I, Lachkar S, Qu B, Waeckel-Énée E, Plo I, Vainchenker W, Perez F, Rodriguez D, López-Otin C, van Endert P, Zitvogel L, Kepp O, Kroemer G.

Mol Cell. 2020 Feb 20;77(4):748-760.e9. doi: 10.1016/j.molcel.2019.11.004. Epub 2019 Nov 27.

PMID:
31785928
24.

Immunostimulatory gut bacteria.

Zitvogel L, Kroemer G.

Science. 2019 Nov 29;366(6469):1077-1078. doi: 10.1126/science.aaz7595. No abstract available.

PMID:
31780546
25.

Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation.

Gehrmann U, Burbage M, Zueva E, Goudot C, Esnault C, Ye M, Carpier JM, Burgdorf N, Hoyler T, Suarez G, Joannas L, Heurtebise-Chrétien S, Durand S, Panes R, Bellemare-Pelletier A, Sáez PJ, Aprahamian F, Lefevre D, Adoue V, Zine El Aabidine A, Muhammad Ahmad M, Hivroz C, Joffre O, Cammas F, Kroemer G, Gagnon E, Andrau JC, Amigorena S.

Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25839-25849. doi: 10.1073/pnas.1901639116. Epub 2019 Nov 27.

26.

Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients.

Kasikova L, Hensler M, Truxova I, Skapa P, Laco J, Belicova L, Praznovec I, Vosahlikova S, Halaska MJ, Brtnicky T, Rob L, Presl J, Kostun J, Cremer I, Ryska A, Kroemer G, Galluzzi L, Spisek R, Fucikova J.

J Immunother Cancer. 2019 Nov 20;7(1):312. doi: 10.1186/s40425-019-0781-z.

27.

Assessment of annexin A1 release during immunogenic cell death.

Baracco EE, Petrazzuolo A, Kroemer G.

Methods Enzymol. 2019;629:71-79. doi: 10.1016/bs.mie.2019.06.010. Epub 2019 Jul 2.

PMID:
31727257
28.

Quantification of eIF2alpha phosphorylation during immunogenic cell death.

Bezu L, Wu Chuang A, Humeau J, Kroemer G, Kepp O.

Methods Enzymol. 2019;629:53-69. doi: 10.1016/bs.mie.2019.04.010. Epub 2019 Apr 27.

PMID:
31727256
29.

Methods for measuring HMGB1 release during immunogenic cell death.

Zhao L, Liu P, Kepp O, Kroemer G.

Methods Enzymol. 2019;629:177-193. doi: 10.1016/bs.mie.2019.05.001. Epub 2019 May 27.

PMID:
31727240
30.

Quinacrine-mediated detection of intracellular ATP.

Forveille S, Humeau J, Sauvat A, Bezu L, Kroemer G, Kepp O.

Methods Enzymol. 2019;629:103-113. doi: 10.1016/bs.mie.2019.05.050. Epub 2019 Jun 17.

PMID:
31727236
31.

Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina.

Notomi S, Ishihara K, Efstathiou NE, Lee JJ, Hisatomi T, Tachibana T, Konstantinou EK, Ueta T, Murakami Y, Maidana DE, Ikeda Y, Kume S, Terasaki H, Sonoda S, Blanz J, Young L, Sakamoto T, Sonoda KH, Saftig P, Ishibashi T, Miller JW, Kroemer G, Vavvas DG.

Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23724-23734. doi: 10.1073/pnas.1906643116. Epub 2019 Nov 7.

32.

The elusive "hunger protein": an appetite-stimulatory factor that is overabundant in human obesity.

Bravo-San Pedro JM, Sica V, Kroemer G.

Mol Cell Oncol. 2019 Oct 15;6(6):e1667193. doi: 10.1080/23723556.2019.1667193. eCollection 2019.

PMID:
31692883
33.

A discovery platform for the identification of caloric restriction mimetics with broad health-improving effects.

Kepp O, Chen G, Carmona-Gutierrez D, Madeo F, Kroemer G.

Autophagy. 2020 Jan;16(1):188-189. doi: 10.1080/15548627.2019.1688984. Epub 2019 Nov 7.

PMID:
31690168
34.

BML-265 and Tyrphostin AG1478 Disperse the Golgi Apparatus and Abolish Protein Transport in Human Cells.

Boncompain G, Gareil N, Tessier S, Lescure A, Jones TR, Kepp O, Kroemer G, Del Nery E, Perez F.

Front Cell Dev Biol. 2019 Oct 11;7:232. doi: 10.3389/fcell.2019.00232. eCollection 2019.

35.

Acyl-CoA-binding protein (ACBP): the elusive 'hunger factor' linking autophagy to food intake.

Pedro JMB, Sica V, Madeo F, Kroemer G.

Cell Stress. 2019 Sep 24;3(10):312-318. doi: 10.15698/cst2019.10.200. Review.

36.

A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice.

Lévesque S, Le Naour J, Pietrocola F, Paillet J, Kremer M, Castoldi F, Baracco EE, Wang Y, Vacchelli E, Stoll G, Jolly A, De La Grange P, Zitvogel L, Kroemer G, Pol JG.

Oncoimmunology. 2019 Sep 7;8(11):e1657375. doi: 10.1080/2162402X.2019.1657375. eCollection 2019.

37.

Lurbinectedin synergizes with immune checkpoint blockade to generate anticancer immunity.

Xie W, Forveille S, Iribarren K, Sauvat A, Senovilla L, Wang Y, Humeau J, Perez-Lanzon M, Zhou H, Martínez-Leal JF, Kroemer G, Kepp O.

Oncoimmunology. 2019 Sep 5;8(11):e1656502. doi: 10.1080/2162402X.2019.1656502. eCollection 2019.

PMID:
31646106
38.

Trial watch: dendritic cell vaccination for cancer immunotherapy.

Sprooten J, Ceusters J, Coosemans A, Agostinis P, De Vleeschouwer S, Zitvogel L, Kroemer G, Galluzzi L, Garg AD.

Oncoimmunology. 2019 Jul 18;8(11):e1638212. doi: 10.1080/2162402X.2019.1638212. eCollection 2019. Review.

PMID:
31646087
39.

Suppression of tumor antigen presentation during aneuploid tumor evolution contributes to immune evasion.

Tripathi R, Modur V, Senovilla L, Kroemer G, Komurov K.

Oncoimmunology. 2019 Sep 6;8(11):1657374. doi: 10.1080/2162402X.2019.1657374. eCollection 2019.

40.

Clinical evidence that immunogenic cell death sensitizes to PD-1/PD-L1 blockade.

Kepp O, Zitvogel L, Kroemer G.

Oncoimmunology. 2019 Jul 22;8(10):e1637188. doi: 10.1080/2162402X.2019.1637188. eCollection 2019.

PMID:
31646079
41.

Caloric restriction promotes the stemness and antitumor activity of T lymphocytes.

Pietrocola F, Kroemer G.

Oncoimmunology. 2019 May 16;8(10):e1616153. doi: 10.1080/2162402X.2019.1616153. eCollection 2019.

PMID:
31646069
42.

Effects of interleukin-2 in immunostimulation and immunosuppression.

Pol JG, Caudana P, Paillet J, Piaggio E, Kroemer G.

J Exp Med. 2020 Jan 6;217(1). pii: e20191247. doi: 10.1084/jem.20191247.

PMID:
31611250
43.

3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB.

Chen G, Xie W, Nah J, Sauvat A, Liu P, Pietrocola F, Sica V, Carmona-Gutierrez D, Zimmermann A, Pendl T, Tadic J, Bergmann M, Hofer SJ, Domuz L, Lachkar S, Markaki M, Tavernarakis N, Sadoshima J, Madeo F, Kepp O, Kroemer G.

EMBO Mol Med. 2019 Nov 7;11(11):e10469. doi: 10.15252/emmm.201910469. Epub 2019 Oct 14.

44.

Pseudodiabetes-not a contraindication for metabolic interventions.

Bravo-San Pedro JM, Sica V, Kroemer G.

Cell Death Dis. 2019 Oct 10;10(10):765. doi: 10.1038/s41419-019-2007-1.

45.

Artificial tethering of LC3 or p62 to organelles is not sufficient to trigger autophagy.

Loos F, Xie W, Sica V, Bravo-San Pedro JM, Souquère S, Pierron G, Lachkar S, Sauvat A, Petrazzuolo A, Jimenez AJ, Perez F, Maiuri MC, Kepp O, Kroemer G.

Cell Death Dis. 2019 Oct 10;10(10):771. doi: 10.1038/s41419-019-2011-5.

46.

Oncolysis without viruses - inducing systemic anticancer immune responses with local therapies.

Kepp O, Marabelle A, Zitvogel L, Kroemer G.

Nat Rev Clin Oncol. 2020 Jan;17(1):49-64. doi: 10.1038/s41571-019-0272-7. Epub 2019 Oct 8. Review.

PMID:
31595049
47.

HIV-1 Envelope Overcomes NLRP3-Mediated Inhibition of F-Actin Polymerization for Viral Entry.

Paoletti A, Allouch A, Caillet M, Saïdi H, Subra F, Nardacci R, Wu Q, Muradova Z, Voisin L, Raza SQ, Law F, Thoreau M, Dakhli H, Delelis O, Poirier-Beaudouin B, Dereuddre-Bosquet N, Le Grand R, Lambotte O, Saez-Cirion A, Pancino G, Ojcius DM, Solary E, Deutsch E, Piacentini M, Gougeon ML, Kroemer G, Perfettini JL.

Cell Rep. 2019 Sep 24;28(13):3381-3394.e7. doi: 10.1016/j.celrep.2019.02.095.

48.

Leptin-Producing Oncolytic Virus Makes Tumor-Infiltrating T Cells Fit, Not Fat.

Kroemer G, Zitvogel L.

Immunity. 2019 Sep 17;51(3):423-425. doi: 10.1016/j.immuni.2019.08.010.

PMID:
31533054
49.

Stress-glucocorticoid-TSC22D3 axis compromises therapy-induced antitumor immunity.

Yang H, Xia L, Chen J, Zhang S, Martin V, Li Q, Lin S, Chen J, Calmette J, Lu M, Fu L, Yang J, Pan Z, Yu K, He J, Morand E, Schlecht-Louf G, Krzysiek R, Zitvogel L, Kang B, Zhang Z, Leader A, Zhou P, Lanfumey L, Shi M, Kroemer G, Ma Y.

Nat Med. 2019 Sep;25(9):1428-1441. doi: 10.1038/s41591-019-0566-4. Epub 2019 Sep 9.

PMID:
31501614
50.

Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade.

Jacquelot N, Yamazaki T, Roberti MP, Duong CPM, Andrews MC, Verlingue L, Ferrere G, Becharef S, Vétizou M, Daillère R, Messaoudene M, Enot DP, Stoll G, Ugel S, Marigo I, Foong Ngiow S, Marabelle A, Prevost-Blondel A, Gaudreau PO, Gopalakrishnan V, Eggermont AM, Opolon P, Klein C, Madonna G, Ascierto PA, Sucker A, Schadendorf D, Smyth MJ, Soria JC, Kroemer G, Bronte V, Wargo J, Zitvogel L.

Cell Res. 2019 Oct;29(10):846-861. doi: 10.1038/s41422-019-0224-x. Epub 2019 Sep 3.

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