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Items: 1 to 50 of 1137

1.

Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?

Madeo F, Bauer MA, Carmona-Gutierrez D, Kroemer G.

Autophagy. 2018 Oct 11:1-4. doi: 10.1080/15548627.2018.1530929. [Epub ahead of print]

PMID:
30306826
2.

Linking cellular stress responses to systemic homeostasis.

Galluzzi L, Yamazaki T, Kroemer G.

Nat Rev Mol Cell Biol. 2018 Oct 10. doi: 10.1038/s41580-018-0068-0. [Epub ahead of print] Review.

PMID:
30305710
3.

Methionine restriction for improving progeria: another autophagy-inducing anti-aging strategy?

Bárcena C, López-Otín C, Kroemer G.

Autophagy. 2018 Oct 10. doi: 10.1080/15548627.2018.1533059. [Epub ahead of print]

PMID:
30304972
4.

Identification of pharmacological inhibitors of conventional protein secretion.

Zhao L, Liu P, Boncompain G, Loos F, Lachkar S, Bezu L, Chen G, Zhou H, Perez F, Kepp O, Kroemer G.

Sci Rep. 2018 Oct 8;8(1):14966. doi: 10.1038/s41598-018-33378-y.

5.

Impact of chemotactic factors and receptors on the cancer immune infiltrate: a bioinformatics study revealing homogeneity and heterogeneity among patient cohorts.

Stoll G, Pol J, Soumelis V, Zitvogel L, Kroemer G.

Oncoimmunology. 2018 Aug 6;7(10):e1484980. doi: 10.1080/2162402X.2018.1484980. eCollection 2018.

6.

The hallmarks of successful anticancer immunotherapy.

Galluzzi L, Chan TA, Kroemer G, Wolchok JD, López-Soto A.

Sci Transl Med. 2018 Sep 19;10(459). pii: eaat7807. doi: 10.1126/scitranslmed.aat7807. Review.

PMID:
30232229
7.

TumGrowth: An open-access web tool for the statistical analysis of tumor growth curves.

Enot DP, Vacchelli E, Jacquelot N, Zitvogel L, Kroemer G.

Oncoimmunology. 2018 Aug 1;7(9):e1462431. doi: 10.1080/2162402X.2018.1462431. eCollection 2018.

8.

Immune effectors responsible for the elimination of hyperploid cancer cells.

Aranda F, Chaba K, Bloy N, Garcia P, Bordenave C, Martins I, Stoll G, Tesniere A, Kroemer G, Senovilla L.

Oncoimmunology. 2018 May 21;7(8):e1463947. doi: 10.1080/2162402X.2018.1463947. eCollection 2018.

PMID:
30221060
9.

Heating it up: Oncolytic viruses make tumors 'hot' and suitable for checkpoint blockade immunotherapies.

Gujar S, Pol JG, Kroemer G.

Oncoimmunology. 2018 Mar 13;7(8):e1442169. doi: 10.1080/2162402X.2018.1442169. eCollection 2018.

10.

Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles.

Bonora M, Wieckowski MR, Sinclair DA, Kroemer G, Pinton P, Galluzzi L.

Nat Rev Cardiol. 2018 Sep 3. doi: 10.1038/s41569-018-0074-0. [Epub ahead of print] Review.

PMID:
30177752
11.

Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism.

Bárcena C, Quirós PM, Durand S, Mayoral P, Rodríguez F, Caravia XM, Mariño G, Garabaya C, Fernández-García MT, Kroemer G, Freije JMP, López-Otín C.

Cell Rep. 2018 Aug 28;24(9):2392-2403. doi: 10.1016/j.celrep.2018.07.089.

12.

MDM2-TP53 Crossregulation: An Underestimated Target to Promote Loss of TP53 Function and Cell Survival.

Soussi T, Kroemer G.

Trends Cancer. 2018 Sep;4(9):602-605. doi: 10.1016/j.trecan.2018.07.001. Epub 2018 Jul 21.

PMID:
30149877
13.

Redaporfin induces immunogenic cell death by selective destruction of the endoplasmic reticulum and the Golgi apparatus.

Gomes-da-Silva LC, Zhao L, Arnaut LG, Kroemer G, Kepp O.

Oncotarget. 2018 Jul 27;9(58):31169-31170. doi: 10.18632/oncotarget.25798. eCollection 2018 Jul 27. No abstract available.

14.

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing.

Boland B, Yu WH, Corti O, Mollereau B, Henriques A, Bezard E, Pastores GM, Rubinsztein DC, Nixon RA, Duchen MR, Mallucci GR, Kroemer G, Levine B, Eskelinen EL, Mochel F, Spedding M, Louis C, Martin OR, Millan MJ.

Nat Rev Drug Discov. 2018 Sep;17(9):660-688. doi: 10.1038/nrd.2018.109. Epub 2018 Aug 17. Review.

PMID:
30116051
15.

PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism.

Li C, Zhang Y, Cheng X, Yuan H, Zhu S, Liu J, Wen Q, Xie Y, Liu J, Kroemer G, Klionsky DJ, Lotze MT, Zeh HJ, Kang R, Tang D.

Dev Cell. 2018 Aug 20;46(4):441-455.e8. doi: 10.1016/j.devcel.2018.07.012. Epub 2018 Aug 9.

PMID:
30100261
16.

Spermidine delays aging in humans.

Madeo F, Carmona-Gutierrez D, Kepp O, Kroemer G.

Aging (Albany NY). 2018 Aug 6;10(8):2209-2211. doi: 10.18632/aging.101517. No abstract available.

17.

The anticancer peptide RT53 induces immunogenic cell death.

Pasquereau-Kotula E, Habault J, Kroemer G, Poyet JL.

PLoS One. 2018 Aug 6;13(8):e0201220. doi: 10.1371/journal.pone.0201220. eCollection 2018.

18.

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc- Activity.

Song X, Zhu S, Chen P, Hou W, Wen Q, Liu J, Xie Y, Liu J, Klionsky DJ, Kroemer G, Lotze MT, Zeh HJ, Kang R, Tang D.

Curr Biol. 2018 Aug 6;28(15):2388-2399.e5. doi: 10.1016/j.cub.2018.05.094. Epub 2018 Jul 26.

PMID:
30057310
19.

Higher spermidine intake is linked to lower mortality: a prospective population-based study.

Kiechl S, Pechlaner R, Willeit P, Notdurfter M, Paulweber B, Willeit K, Werner P, Ruckenstuhl C, Iglseder B, Weger S, Mairhofer B, Gartner M, Kedenko L, Chmelikova M, Stekovic S, Stuppner H, Oberhollenzer F, Kroemer G, Mayr M, Eisenberg T, Tilg H, Madeo F, Willeit J.

Am J Clin Nutr. 2018 Aug 1;108(2):371-380. doi: 10.1093/ajcn/nqy102.

PMID:
29955838
20.

Reply to 'F508del-CFTR is not corrected by thymosin α1'.

Romani L, Stincardini C, Giovagnoli S, Paci M, Villella VR, Sforna L, Renga G, Bellet MM, Costantini C, Puccetti P, Kroemer G, Maiuri L, Pessia M, Goldstein A, Garaci E.

Nat Med. 2018 Jul;24(7):891-893. doi: 10.1038/s41591-018-0080-0. No abstract available.

PMID:
29942090
21.

Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations.

Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Sklar LA, Allers L, Garcia SA, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, Eskelinen EL, Fourie B, Gozuacik D, Hong W, Hotamisligi G, Jäättelä M, Jo EK, Johansen T, Juhász G, Kimchi A, Ktistakis N, Kroemer G, MIzushima N, Münz C, Reggiori F, Rubinsztein D, Ryan K, Schroder K, Simonsen A, Tooze S, Vaccaro MI, Yoshimori T, Yu L, Zhang H, Klionsky DJ.

Autophagy. 2018;14(6):925-929. doi: 10.1080/15548627.2018.1465784.

PMID:
29938597
22.

Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis.

Kang R, Zeng L, Zhu S, Xie Y, Liu J, Wen Q, Cao L, Xie M, Ran Q, Kroemer G, Wang H, Billiar TR, Jiang J, Tang D.

Cell Host Microbe. 2018 Jul 11;24(1):97-108.e4. doi: 10.1016/j.chom.2018.05.009. Epub 2018 Jun 21.

PMID:
29937272
23.

Publisher Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.

Romani L, Oikonomou V, Moretti S, Iannitti RG, D'Adamo MC, Villella VR, Pariano M, Sforna L, Borghi M, Bellet MM, Fallarino F, Pallotta MT, Servillo G, Ferrari E, Puccetti P, Kroemer G, Pessia M, Maiuri L, Goldstein AL, Garaci E.

Nat Med. 2018 Sep;24(9):1482. doi: 10.1038/s41591-018-0099-2.

PMID:
29934535
24.

Author Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.

Romani L, Oikonomou V, Moretti S, Iannitti RG, D'Adamo MC, Villella VR, Pariano M, Sforna L, Borghi M, Bellet MM, Fallarino F, Pallotta MT, Servillo G, Ferrari E, Puccetti P, Kroemer G, Pessia M, Maiuri L, Goldstein AL, Garaci E.

Nat Med. 2018 Sep;24(9):1481. doi: 10.1038/s41591-018-0100-0.

PMID:
29934534
25.

Aspirin-another caloric-restriction mimetic.

Pietrocola F, Castoldi F, Maiuri MC, Kroemer G.

Autophagy. 2018 Jul 18:1-2. doi: 10.1080/15548627.2018.1454810. [Epub ahead of print]

PMID:
29929449
26.

Author Correction: IMMP2L: a mitochondrial protease suppressing cellular senescence.

Sica V, Kroemer G.

Cell Res. 2018 Jul;28(7):782. doi: 10.1038/s41422-018-0059-x.

27.

Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death.

Martins I, Raza SQ, Voisin L, Dakhli H, Allouch A, Law F, Sabino D, De Jong D, Thoreau M, Mintet E, Dugué D, Piacentini M, Gougeon ML, Jaulin F, Bertrand P, Brenner C, Ojcius DM, Kroemer G, Modjtahedi N, Deutsch E, Perfettini JL.

Cell Death Dis. 2018 Jun 18;9(7):716. doi: 10.1038/s41419-018-0747-y.

28.

Metabolic vulnerability of cisplatin-resistant cancers.

Obrist F, Michels J, Durand S, Chery A, Pol J, Levesque S, Joseph A, Astesana V, Pietrocola F, Wu GS, Castedo M, Kroemer G.

EMBO J. 2018 Jul 13;37(14). pii: e98597. doi: 10.15252/embj.201798597. Epub 2018 Jun 6.

PMID:
29875130
29.

The intestinal microbiota determines the clinical efficacy of immune checkpoint blockers targeting PD-1/PD-L1.

Derosa L, Routy B, Kroemer G, Zitvogel L.

Oncoimmunology. 2018 Apr 18;7(6):e1434468. doi: 10.1080/2162402X.2018.1434468. eCollection 2018.

PMID:
29872574
30.

Trial Watch: Immunostimulation with recombinant cytokines for cancer therapy.

García-Martínez E, Smith M, Buqué A, Aranda F, de la Peña FA, Ivars A, Cánovas MS, Conesa MAV, Fucikova J, Spisek R, Zitvogel L, Kroemer G, Galluzzi L.

Oncoimmunology. 2018 Feb 15;7(6):e1433982. doi: 10.1080/2162402X.2018.1433982. eCollection 2018. Review.

PMID:
29872569
31.

Epigenetic anticancer agents cause HMGB1 release in vivo.

Liu P, Zhao L, Loos F, Iribarren K, Kepp O, Kroemer G.

Oncoimmunology. 2018 Feb 14;7(6):e1431090. doi: 10.1080/2162402X.2018.1431090. eCollection 2018.

PMID:
29872561
32.

eIF2α phosphorylation: A hallmark of immunogenic cell death.

Bezu L, Sauvat A, Humeau J, Leduc M, Kepp O, Kroemer G.

Oncoimmunology. 2018 Feb 14;7(6):e1431089. doi: 10.1080/2162402X.2018.1431089. eCollection 2018.

PMID:
29872560
33.

TFAM is a novel mediator of immunogenic cancer cell death.

Yang M, Li C, Zhu S, Cao L, Kroemer G, Zeh H, Tang D, Kang R.

Oncoimmunology. 2018 Feb 15;7(6):e1431086. doi: 10.1080/2162402X.2018.1431086. eCollection 2018.

34.

Aspirin induces autophagy via inhibition of the acetyltransferase EP300.

Castoldi F, Pietrocola F, Maiuri MC, Kroemer G.

Oncotarget. 2018 May 15;9(37):24574-24575. doi: 10.18632/oncotarget.25364. eCollection 2018 May 15. No abstract available.

35.

IMMP2L: a mitochondrial protease suppressing cellular senescence.

Sica V, Kroemer G.

Cell Res. 2018 Jun;28(6):607-608. doi: 10.1038/s41422-018-0051-5. No abstract available. Erratum in: Cell Res. 2018 Jul;28(7):782.

PMID:
29844577
36.

Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus.

Gomes-da-Silva LC, Zhao L, Bezu L, Zhou H, Sauvat A, Liu P, Durand S, Leduc M, Souquere S, Loos F, Mondragón L, Sveinbjørnsson B, Rekdal Ø, Boncompain G, Perez F, Arnaut LG, Kepp O, Kroemer G.

EMBO J. 2018 Jul 2;37(13). pii: e98354. doi: 10.15252/embj.201798354. Epub 2018 May 28.

PMID:
29807932
37.

The tumor suppressor protein p53 and the ferroptosis network.

Kang R, Kroemer G, Tang D.

Free Radic Biol Med. 2018 May 23. pii: S0891-5849(18)30907-9. doi: 10.1016/j.freeradbiomed.2018.05.074. [Epub ahead of print] Review.

PMID:
29800655
38.

TG2 regulates the heat-shock response by the post-translational modification of HSF1.

Rossin F, Villella VR, D'Eletto M, Farrace MG, Esposito S, Ferrari E, Monzani R, Occhigrossi L, Pagliarini V, Sette C, Cozza G, Barlev NA, Falasca L, Fimia GM, Kroemer G, Raia V, Maiuri L, Piacentini M.

EMBO Rep. 2018 Jul;19(7). pii: e45067. doi: 10.15252/embr.201745067. Epub 2018 May 11.

PMID:
29752334
39.

The gut microbiota influences anticancer immunosurveillance and general health.

Routy B, Gopalakrishnan V, Daillère R, Zitvogel L, Wargo JA, Kroemer G.

Nat Rev Clin Oncol. 2018 Jun;15(6):382-396. doi: 10.1038/s41571-018-0006-2. Review.

PMID:
29636538
40.

Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids.

Sauvat A, Chen G, Müller K, Tong M, Aprahamian F, Durand S, Cerrato G, Bezu L, Leduc M, Franz J, Rockenfeller P, Sadoshima J, Madeo F, Kepp O, Kroemer G.

EBioMedicine. 2018 Apr;30:261-272. doi: 10.1016/j.ebiom.2018.03.028. Epub 2018 Mar 27.

41.

Anti-CTLA-4 immunotherapy: uncoupling toxicity and efficacy.

Pol J, Kroemer G.

Cell Res. 2018 May;28(5):501-502. doi: 10.1038/s41422-018-0031-9. Epub 2018 Mar 28. No abstract available.

PMID:
29593340
42.

The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies.

Zitvogel L, Ma Y, Raoult D, Kroemer G, Gajewski TF.

Science. 2018 Mar 23;359(6382):1366-1370. doi: 10.1126/science.aar6918. Review.

PMID:
29567708
43.

Organoids for Modeling Genetic Diseases.

Perez-Lanzon M, Kroemer G, Maiuri MC.

Int Rev Cell Mol Biol. 2018;337:49-81. doi: 10.1016/bs.ircmb.2017.12.006. Epub 2018 Feb 12.

PMID:
29551162
44.

Aspirin Recapitulates Features of Caloric Restriction.

Pietrocola F, Castoldi F, Markaki M, Lachkar S, Chen G, Enot DP, Durand S, Bossut N, Tong M, Malik SA, Loos F, Dupont N, Mariño G, Abdelkader N, Madeo F, Maiuri MC, Kroemer R, Codogno P, Sadoshima J, Tavernarakis N, Kroemer G.

Cell Rep. 2018 Feb 27;22(9):2395-2407. doi: 10.1016/j.celrep.2018.02.024.

45.

Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere.

Abrahão J, Silva L, Silva LS, Khalil JYB, Rodrigues R, Arantes T, Assis F, Boratto P, Andrade M, Kroon EG, Ribeiro B, Bergier I, Seligmann H, Ghigo E, Colson P, Levasseur A, Kroemer G, Raoult D, La Scola B.

Nat Commun. 2018 Feb 27;9(1):749. doi: 10.1038/s41467-018-03168-1.

46.

The autophagic network and cancer.

Rybstein MD, Bravo-San Pedro JM, Kroemer G, Galluzzi L.

Nat Cell Biol. 2018 Mar;20(3):243-251. doi: 10.1038/s41556-018-0042-2. Epub 2018 Feb 23. Review.

PMID:
29476153
47.

Bax inhibitor-1 protects from nonalcoholic steatohepatitis by limiting inositol-requiring enzyme 1 alpha signaling in mice.

Lebeaupin C, Vallée D, Rousseau D, Patouraux S, Bonnafous S, Adam G, Luciano F, Luci C, Anty R, Iannelli A, Marchetti S, Kroemer G, Lacas-Gervais S, Tran A, Gual P, Bailly-Maitre B.

Hepatology. 2018 Aug;68(2):515-532. doi: 10.1002/hep.29847. Epub 2018 May 18.

PMID:
29457838
48.

Evaluation of autophagy inducers in epithelial cells carrying the ΔF508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR.

Zhang S, Stoll G, Pedro JMBS, Sica V, Sauvat A, Obrist F, Kepp O, Li Y, Maiuri L, Zamzami N, Kroemer G.

Cell Death Dis. 2018 Feb 7;9(2):191. doi: 10.1038/s41419-017-0235-9.

49.

Cancer immunotherapy in 2017: The breakthrough of the microbiota.

Kroemer G, Zitvogel L.

Nat Rev Immunol. 2018 Jan 30;18(2):87-88. doi: 10.1038/nri.2018.4. No abstract available.

PMID:
29379189
50.

Spermidine in health and disease.

Madeo F, Eisenberg T, Pietrocola F, Kroemer G.

Science. 2018 Jan 26;359(6374). pii: eaan2788. doi: 10.1126/science.aan2788. Review.

PMID:
29371440

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