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Items: 1 to 50 of 1222

1.

Pseudodiabetes-not a contraindication for metabolic interventions.

Bravo-San Pedro JM, Sica V, Kroemer G.

Cell Death Dis. 2019 Oct 10;10(10):765. doi: 10.1038/s41419-019-2007-1.

PMID:
31601789
2.

Artificial tethering of LC3 or p62 to organelles is not sufficient to trigger autophagy.

Loos F, Xie W, Sica V, Bravo-San Pedro JM, Souquère S, Pierron G, Lachkar S, Sauvat A, Petrazzuolo A, Jimenez AJ, Perez F, Maiuri MC, Kepp O, Kroemer G.

Cell Death Dis. 2019 Oct 10;10(10):771. doi: 10.1038/s41419-019-2011-5.

PMID:
31601788
3.

Oncolysis without viruses - inducing systemic anticancer immune responses with local therapies.

Kepp O, Marabelle A, Zitvogel L, Kroemer G.

Nat Rev Clin Oncol. 2019 Oct 8. doi: 10.1038/s41571-019-0272-7. [Epub ahead of print] Review.

PMID:
31595049
4.

HIV-1 Envelope Overcomes NLRP3-Mediated Inhibition of F-Actin Polymerization for Viral Entry.

Paoletti A, Allouch A, Caillet M, Saïdi H, Subra F, Nardacci R, Wu Q, Muradova Z, Voisin L, Raza SQ, Law F, Thoreau M, Dakhli H, Delelis O, Poirier-Beaudouin B, Dereuddre-Bosquet N, Le Grand R, Lambotte O, Saez-Cirion A, Pancino G, Ojcius DM, Solary E, Deutsch E, Piacentini M, Gougeon ML, Kroemer G, Perfettini JL.

Cell Rep. 2019 Sep 24;28(13):3381-3394.e7. doi: 10.1016/j.celrep.2019.02.095.

5.

Leptin-Producing Oncolytic Virus Makes Tumor-Infiltrating T Cells Fit, Not Fat.

Kroemer G, Zitvogel L.

Immunity. 2019 Sep 17;51(3):423-425. doi: 10.1016/j.immuni.2019.08.010.

PMID:
31533054
6.

Stress-glucocorticoid-TSC22D3 axis compromises therapy-induced antitumor immunity.

Yang H, Xia L, Chen J, Zhang S, Martin V, Li Q, Lin S, Chen J, Calmette J, Lu M, Fu L, Yang J, Pan Z, Yu K, He J, Morand E, Schlecht-Louf G, Krzysiek R, Zitvogel L, Kang B, Zhang Z, Leader A, Zhou P, Lanfumey L, Shi M, Kroemer G, Ma Y.

Nat Med. 2019 Sep;25(9):1428-1441. doi: 10.1038/s41591-019-0566-4. Epub 2019 Sep 9.

PMID:
31501614
7.

Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade.

Jacquelot N, Yamazaki T, Roberti MP, Duong CPM, Andrews MC, Verlingue L, Ferrere G, Becharef S, Vétizou M, Daillère R, Messaoudene M, Enot DP, Stoll G, Ugel S, Marigo I, Foong Ngiow S, Marabelle A, Prevost-Blondel A, Gaudreau PO, Gopalakrishnan V, Eggermont AM, Opolon P, Klein C, Madonna G, Ascierto PA, Sucker A, Schadendorf D, Smyth MJ, Soria JC, Kroemer G, Bronte V, Wargo J, Zitvogel L.

Cell Res. 2019 Oct;29(10):846-861. doi: 10.1038/s41422-019-0224-x. Epub 2019 Sep 3.

PMID:
31481761
8.

Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans.

Stekovic S, Hofer SJ, Tripolt N, Aon MA, Royer P, Pein L, Stadler JT, Pendl T, Prietl B, Url J, Schroeder S, Tadic J, Eisenberg T, Magnes C, Stumpe M, Zuegner E, Bordag N, Riedl R, Schmidt A, Kolesnik E, Verheyen N, Springer A, Madl T, Sinner F, de Cabo R, Kroemer G, Obermayer-Pietsch B, Dengjel J, Sourij H, Pieber TR, Madeo F.

Cell Metab. 2019 Sep 3;30(3):462-476.e5. doi: 10.1016/j.cmet.2019.07.016. Epub 2019 Aug 27.

PMID:
31471173
9.

Cell-autonomous, paracrine and neuroendocrine feedback regulation of autophagy by DBI/ACBP (diazepam binding inhibitor, acyl-CoA binding protein): the obesity factor.

Bravo-San Pedro JM, Sica V, Martins I, Anagnostopoulos G, Maiuri C, Kroemer G.

Autophagy. 2019 Nov;15(11):2036-2038. doi: 10.1080/15548627.2019.1662585. Epub 2019 Sep 5.

PMID:
31470770
10.

A strategy for poisoning cancer cell metabolism: Inhibition of oxidative phosphorylation coupled to anaplerotic saturation.

Sica V, Bravo-San Pedro JM, Kroemer G.

Int Rev Cell Mol Biol. 2019;347:27-37. doi: 10.1016/bs.ircmb.2019.07.002. Epub 2019 Jul 29.

PMID:
31451215
11.

Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity.

Bravo-San Pedro JM, Sica V, Martins I, Pol J, Loos F, Maiuri MC, Durand S, Bossut N, Aprahamian F, Anagnostopoulos G, Niso-Santano M, Aranda F, Ramírez-Pardo I, Lallement J, Denom J, Boedec E, Gorwood P, Ramoz N, Clément K, Pelloux V, Rohia A, Pattou F, Raverdy V, Caiazzo R, Denis RGP, Boya P, Galluzzi L, Madeo F, Migrenne-Li S, Cruciani-Guglielmacci C, Tavernarakis N, López-Otín C, Magnan C, Kroemer G.

Cell Metab. 2019 Oct 1;30(4):754-767.e9. doi: 10.1016/j.cmet.2019.07.010. Epub 2019 Aug 15.

PMID:
31422903
12.

A fluorescent biosensor-based platform for the discovery of immunogenic cancer cell death inducers.

Kepp O, Sauvat A, Leduc M, Forveille S, Liu P, Zhao L, Bezu L, Xie W, Zitvogel L, Kroemer G.

Oncoimmunology. 2019 Apr 26;8(8):1606665. doi: 10.1080/2162402X.2019.1606665. eCollection 2019. Review.

PMID:
31413915
13.

Oxidative phosphorylation as a potential therapeutic target for cancer therapy.

Sica V, Bravo-San Pedro JM, Stoll G, Kroemer G.

Int J Cancer. 2019 Aug 9. doi: 10.1002/ijc.32616. [Epub ahead of print] Review.

PMID:
31396957
14.

Optimising efficacy and reducing toxicity of anticancer radioimmunotherapy.

Deutsch E, Chargari C, Galluzzi L, Kroemer G.

Lancet Oncol. 2019 Aug;20(8):e452-e463. doi: 10.1016/S1470-2045(19)30171-8. Epub 2019 Jul 29. Review.

PMID:
31364597
15.

Clockophagy is a novel selective autophagy process favoring ferroptosis.

Yang M, Chen P, Liu J, Zhu S, Kroemer G, Klionsky DJ, Lotze MT, Zeh HJ, Kang R, Tang D.

Sci Adv. 2019 Jul 24;5(7):eaaw2238. doi: 10.1126/sciadv.aaw2238. eCollection 2019 Jul.

16.

The metabolomic signature of extreme longevity: naked mole rats versus mice.

Viltard M, Durand S, Pérez-Lanzón M, Aprahamian F, Lefevre D, Leroy C, Madeo F, Kroemer G, Friedlander G.

Aging (Albany NY). 2019 Jul 24;11(14):4783-4800. doi: 10.18632/aging.102116.

17.

Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice.

Bárcena C, Valdés-Mas R, Mayoral P, Garabaya C, Durand S, Rodríguez F, Fernández-García MT, Salazar N, Nogacka AM, Garatachea N, Bossut N, Aprahamian F, Lucia A, Kroemer G, Freije JMP, Quirós PM, López-Otín C.

Nat Med. 2019 Aug;25(8):1234-1242. doi: 10.1038/s41591-019-0504-5. Epub 2019 Jul 22.

PMID:
31332389
18.

The Molecular Hallmarks of the Serrated Pathway in Colorectal Cancer.

De Palma FDE, D'Argenio V, Pol J, Kroemer G, Maiuri MC, Salvatore F.

Cancers (Basel). 2019 Jul 20;11(7). pii: E1017. doi: 10.3390/cancers11071017. Review.

19.

Cystic fibrosis transmembrane conductance regulator (CFTR) and autophagy: hereditary defects in cystic fibrosis versus gluten-mediated inhibition in celiac disease.

Maiuri L, Raia V, Piacentini M, Tosco A, Villella VR, Kroemer G.

Oncotarget. 2019 Jul 8;10(43):4492-4500. doi: 10.18632/oncotarget.27037. eCollection 2019 Jul 8. Review.

20.

Macrophages and Metabolism in the Tumor Microenvironment.

Vitale I, Manic G, Coussens LM, Kroemer G, Galluzzi L.

Cell Metab. 2019 Jul 2;30(1):36-50. doi: 10.1016/j.cmet.2019.06.001. Review.

PMID:
31269428
21.

The negative impact of antibiotics on outcomes in cancer patients treated with immunotherapy: a new independent prognostic factor?

Elkrief A, Derosa L, Kroemer G, Zitvogel L, Routy B.

Ann Oncol. 2019 Jul 3. pii: mdz206. doi: 10.1093/annonc/mdz206. [Epub ahead of print]

PMID:
31268133
22.

4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects.

Zimmermann A, Kainz K, Hofer SJ, Bauer MA, Schroeder S, Dengjel J, Pietrocola F, Kepp O, Ruckenstuhl C, Eisenberg T, Sigrist SJ, Madeo F, Carmona-Gutierrez D, Kroemer G.

Autophagy. 2019 Sep;15(9):1662-1664. doi: 10.1080/15548627.2019.1632623. Epub 2019 Jun 28.

23.

Autophagy, Inflammation, and Metabolism (AIM) Center in its second year.

Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Liu M, Hall P, Sklar LA, Allers L, Mariscal L, Garcia SA, Weaver J, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, Eskelinen EL, Fourie B, Gozuacik D, Hong W, Jo EK, Johansen T, Juhász G, Kimchi A, Ktistakis N, Kroemer G, Mizushima N, Münz C, Reggiori F, Rubinsztein D, Ryan K, Schroder K, Shen HM, Simonsen A, Tooze SA, Vaccaro M, Yoshimori T, Yu L, Zhang H, Klionsky DJ.

Autophagy. 2019 Oct;15(10):1829-1833. doi: 10.1080/15548627.2019.1634444. Epub 2019 Jul 15.

PMID:
31234750
24.

Autophagy represses hepatic carcinogenesis.

Paillet J, Kroemer G.

Mol Cell Oncol. 2019 May 13;6(4):1573080. doi: 10.1080/23723556.2019.1573080. eCollection 2019. Review.

PMID:
31211229
25.

Publisher Correction: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.

Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, Sagredo A, Bustos G, Hazari Y, Ramos-Fernández E, Sassano ML, Pihán P, van Vliet AR, González-Quiroz M, Torres AK, Tapia-Rojas C, Kerkhofs M, Vicente R, Kaufman RJ, Inestrosa NC, Gonzalez-Billault C, Wiseman RL, Agostinis P, Bultynck G, Court FA, Kroemer G, Cárdenas JC, Hetz C.

Nat Cell Biol. 2019 Jul;21(7):913. doi: 10.1038/s41556-019-0355-9.

PMID:
31201389
26.

A transcriptional signature associated with non-Hodgkin lymphoma in the blood of patients with Q fever.

Melenotte C, Mezouar S, Ben Amara A, Benatti S, Chiaroni J, Devaux C, Costello R, Kroemer G, Mege JL, Raoult D.

PLoS One. 2019 Jun 10;14(6):e0217542. doi: 10.1371/journal.pone.0217542. eCollection 2019.

27.

α-Ketoglutarate inhibits autophagy.

Baracco EE, Castoldi F, Durand S, Enot DP, Tadic J, Kainz K, Madeo F, Chery A, Izzo V, Maiuri MC, Pietrocola F, Kroemer G.

Aging (Albany NY). 2019 Jun 7;11(11):3418-3431. doi: 10.18632/aging.102001.

28.

Decelerating ageing and biological clocks by autophagy.

Lopez-Otín C, Kroemer G.

Nat Rev Mol Cell Biol. 2019 Jul;20(7):385-386. doi: 10.1038/s41580-019-0149-8. No abstract available.

PMID:
31164727
29.

Interferon-γ induces cancer cell ferroptosis.

Zitvogel L, Kroemer G.

Cell Res. 2019 Sep;29(9):692-693. doi: 10.1038/s41422-019-0186-z. No abstract available.

PMID:
31160718
30.

Crizotinib - a tyrosine kinase inhibitor that stimulates immunogenic cell death.

Liu P, Zhao L, Kepp O, Kroemer G.

Oncoimmunology. 2019 Apr 13;8(7):1596652. doi: 10.1080/2162402X.2019.1596652. eCollection 2019.

PMID:
31143519
31.

Tumor lysis with LTX-401 creates anticancer immunity.

Xie W, Mondragón L, Mauseth B, Wang Y, Pol J, Lévesque S, Zhou H, Yamazaki T, Eksteen JJ, Zitvogel L, Sveinbjørnsson B, Rekdal Ø, Kepp O, Kroemer G.

Oncoimmunology. 2019 Apr 13;8(7):1594555. doi: 10.1080/2162402X.2019.1594555. eCollection 2019.

PMID:
31143516
32.

Trial watch: dietary interventions for cancer therapy.

Lévesque S, Pol JG, Ferrere G, Galluzzi L, Zitvogel L, Kroemer G.

Oncoimmunology. 2019 Apr 3;8(7):1591878. doi: 10.1080/2162402X.2019.1591878. eCollection 2019. Review.

33.

AIF-regulated oxidative phosphorylation supports lung cancer development.

Rao S, Mondragón L, Pranjic B, Hanada T, Stoll G, Köcher T, Zhang P, Jais A, Lercher A, Bergthaler A, Schramek D, Haigh K, Sica V, Leduc M, Modjtahedi N, Pai TP, Onji M, Uribesalgo I, Hanada R, Kozieradzki I, Koglgruber R, Cronin SJ, She Z, Quehenberger F, Popper H, Kenner L, Haigh JJ, Kepp O, Rak M, Cai K, Kroemer G, Penninger JM.

Cell Res. 2019 Jul;29(7):579-591. doi: 10.1038/s41422-019-0181-4. Epub 2019 May 27.

PMID:
31133695
34.

cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis.

Chen R, Zeng L, Zhu S, Liu J, Zeh HJ, Kroemer G, Wang H, Billiar TR, Jiang J, Tang D, Kang R.

Sci Adv. 2019 May 22;5(5):eaav5562. doi: 10.1126/sciadv.aav5562. eCollection 2019 May.

35.

Targeting GATA transcription factors - a novel strategy for anti-aging interventions?

Zimmermann A, Kainz K, Hofer SJ, Bauer MA, Schroeder S, Dengjel J, Pietrocola F, Kepp O, Ruckenstuhl C, Eisenberg T, Sigrist SJ, Madeo F, Kroemer G, Carmona-Gutierrez D.

Microb Cell. 2019 May 6;6(5):212-216. doi: 10.15698/mic2019.05.676.

36.

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.

Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, Sagredo A, Bustos G, Hazari Y, Ramos-Fernández E, Sassano ML, Pihán P, van Vliet AR, González-Quiroz M, Torres AK, Tapia-Rojas C, Kerkhofs M, Vicente R, Kaufman RJ, Inestrosa NC, Gonzalez-Billault C, Wiseman RL, Agostinis P, Bultynck G, Court FA, Kroemer G, Cárdenas JC, Hetz C.

Nat Cell Biol. 2019 Jun;21(6):755-767. doi: 10.1038/s41556-019-0329-y. Epub 2019 May 20. Erratum in: Nat Cell Biol. 2019 Jun 14;:.

PMID:
31110288
37.

Metabolic enzymes expressed by cancer cells impact the immune infiltrate.

Stoll G, Kremer M, Bloy N, Joseph A, Castedo M, Meurice G, Klein C, Galluzzi L, Michels J, Kroemer G.

Oncoimmunology. 2019 Mar 30;8(6):e1571389. doi: 10.1080/2162402X.2019.1571389. eCollection 2019.

PMID:
31069148
38.

Author Correction: Crizotinib-induced immunogenic cell death in non-small cell lung cancer.

Liu P, Zhao L, Pol J, Levesque S, Petrazzuolo A, Pfirschke C, Engblom C, Rickelt S, Yamazaki T, Iribarren K, Senovilla L, Bezu L, Vacchelli E, Sica V, Melis A, Martin T, Xia L, Yang H, Li Q, Chen J, Durand S, Aprahamian F, Lefevre D, Broutin S, Paci A, Bongers A, Minard-Colin V, Tartour E, Zitvogel L, Apetoh L, Ma Y, Pittet MJ, Kepp O, Kroemer G.

Nat Commun. 2019 Apr 17;10(1):1883. doi: 10.1038/s41467-019-09838-y.

39.

Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate.

Sica V, Bravo-San Pedro JM, Izzo V, Pol J, Pierredon S, Enot D, Durand S, Bossut N, Chery A, Souquere S, Pierron G, Vartholomaiou E, Zamzami N, Soussi T, Sauvat A, Mondragón L, Kepp O, Galluzzi L, Martinou JC, Hess-Stumpp H, Ziegelbauer K, Kroemer G, Maiuri MC.

Cell Rep. 2019 Apr 16;27(3):820-834.e9. doi: 10.1016/j.celrep.2019.03.058.

40.

Genistein antagonizes gliadin-induced CFTR malfunction in models of celiac disease.

Esposito S, Villella VR, Ferrari E, Monzani R, Tosco A, Rossin F, D'Eletto M, Castaldo A, Luciani A, Silano M, Bona G, Marseglia GL, Romani L, Piacentini M, Raia V, Kroemer G, Maiuri L.

Aging (Albany NY). 2019 Apr 12;11(7):2003-2019. doi: 10.18632/aging.101888.

41.

Cancer Cells Thrive on Stress.

Galluzzi L, Kroemer G.

Trends Cell Biol. 2019 Jun;29(6):447-449. doi: 10.1016/j.tcb.2019.03.005. Epub 2019 Apr 5.

PMID:
30962044
42.

The molecular machinery of regulated cell death.

Tang D, Kang R, Berghe TV, Vandenabeele P, Kroemer G.

Cell Res. 2019 May;29(5):347-364. doi: 10.1038/s41422-019-0164-5. Epub 2019 Apr 4. Review.

PMID:
30948788
43.

Author Correction: Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux.

Zhang S, Wang Y, Xie W, Howe ENW, Busschaert N, Sauvat A, Leduc M, Gomes-da-Silva LC, Chen G, Martins I, Deng X, Maiuri L, Kepp O, Soussi T, Gale PA, Zamzami N, Kroemer G.

Cell Death Dis. 2019 Apr 3;10(4):301. doi: 10.1038/s41419-019-1536-y.

44.

Crizotinib-induced immunogenic cell death in non-small cell lung cancer.

Liu P, Zhao L, Pol J, Levesque S, Petrazzuolo A, Pfirschke C, Engblom C, Rickelt S, Yamazaki T, Iribarren K, Senovilla L, Bezu L, Vacchelli E, Sica V, Melis A, Martin T, Xia L, Yang H, Li Q, Chen J, Durand S, Aprahamian F, Lefevre D, Broutin S, Paci A, Bongers A, Minard-Colin V, Tartour E, Zitvogel L, Apetoh L, Ma Y, Pittet MJ, Kepp O, Kroemer G.

Nat Commun. 2019 Apr 2;10(1):1486. doi: 10.1038/s41467-019-09415-3. Erratum in: Nat Commun. 2019 Apr 17;10(1):1883.

45.

T cell Bispecific Antibodies in Node-Positive Breast Cancer: Novel Therapeutic Avenue for MHC class I Loss Variants.

Messaoudene M, Mourikis TP, Michels J, Fu Y, Bonvalet M, Lacroix-Trikki M, Routy B, Fluckiger A, Rusakiewicz S, Roberti MP, Cotteret S, Flament C, Poirier-Colame V, Jacquelot N, Ghiringhelli F, Caignard A, Eggermont AMM, Kroemer G, Marabelle A, Arnedos M, Vicier C, Dogan S, Jaulin F, Sammut SJ, Cope W, Caldas C, Delaloge S, McGranahan N, André F, Zitvogel L.

Ann Oncol. 2019 Mar 29. pii: mdz112. doi: 10.1093/annonc/mdz112. [Epub ahead of print]

PMID:
30924846
46.

Failure of immunosurveillance accelerates aging.

Perez-Lanzon M, Zitvogel L, Kroemer G.

Oncoimmunology. 2019 Feb 9;8(4):e1575117. doi: 10.1080/2162402X.2019.1575117. eCollection 2019.

47.

The gliadin-CFTR connection: new perspectives for the treatment of celiac disease.

Maiuri L, Villella VR, Raia V, Kroemer G.

Ital J Pediatr. 2019 Mar 21;45(1):40. doi: 10.1186/s13052-019-0627-9.

48.

Ferroptosis is a type of autophagy-dependent cell death.

Zhou B, Liu J, Kang R, Klionsky DJ, Kroemer G, Tang D.

Semin Cancer Biol. 2019 Mar 14. pii: S1044-579X(19)30006-9. doi: 10.1016/j.semcancer.2019.03.002. [Epub ahead of print] Review.

PMID:
30880243
49.

Autophagy suppresses the pathogenic immune response to dietary antigens in cystic fibrosis.

Villella VR, Esposito S, Ferrari E, Monzani R, Tosco A, Rossin F, Castaldo A, Silano M, Marseglia GL, Romani L, Barlev NA, Piacentini M, Raia V, Kroemer G, Maiuri L.

Cell Death Dis. 2019 Mar 15;10(4):258. doi: 10.1038/s41419-019-1500-x.

50.

Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux.

Zhang S, Wang Y, Xie W, Howe ENW, Busschaert N, Sauvat A, Leduc M, Gomes-da-Silva LC, Chen G, Martins I, Deng X, Maiuri L, Kepp O, Soussi T, Gale PA, Zamzami N, Kroemer G.

Cell Death Dis. 2019 Mar 11;10(3):242. doi: 10.1038/s41419-019-1474-8. Erratum in: Cell Death Dis. 2019 Apr 3;10(4):301.

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