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Items: 12

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1.

Bioelectronic modulation of carotid sinus nerve activity in the rat: a potential therapeutic approach for type 2 diabetes.

Sacramento JF, Chew DJ, Melo BF, Donegá M, Dopson W, Guarino MP, Robinson A, Prieto-Lloret J, Patel S, Holinski BJ, Ramnarain N, Pikov V, Famm K, Conde SV.

Diabetologia. 2018 Mar;61(3):700-710. doi: 10.1007/s00125-017-4533-7. Epub 2018 Jan 14.

PMID:
29332196
2.

Catalytic in vivo protein knockdown by small-molecule PROTACs.

Bondeson DP, Mares A, Smith IE, Ko E, Campos S, Miah AH, Mulholland KE, Routly N, Buckley DL, Gustafson JL, Zinn N, Grandi P, Shimamura S, Bergamini G, Faelth-Savitski M, Bantscheff M, Cox C, Gordon DA, Willard RR, Flanagan JJ, Casillas LN, Votta BJ, den Besten W, Famm K, Kruidenier L, Carter PS, Harling JD, Churcher I, Crews CM.

Nat Chem Biol. 2015 Aug;11(8):611-7. doi: 10.1038/nchembio.1858. Epub 2015 Jun 10.

3.

Bioelectronic medicines: a research roadmap.

Birmingham K, Gradinaru V, Anikeeva P, Grill WM, Pikov V, McLaughlin B, Pasricha P, Weber D, Ludwig K, Famm K.

Nat Rev Drug Discov. 2014 Jun;13(6):399-400. doi: 10.1038/nrd4351. No abstract available.

PMID:
24875080
4.

Drug discovery: a jump-start for electroceuticals.

Famm K, Litt B, Tracey KJ, Boyden ES, Slaoui M.

Nature. 2013 Apr 11;496(7444):159-61. doi: 10.1038/496159a. No abstract available.

5.

Selection of human VH single domains with improved biophysical properties by phage display.

Dudgeon K, Rouet R, Famm K, Christ D.

Methods Mol Biol. 2012;911:383-97. doi: 10.1007/978-1-61779-968-6_23.

PMID:
22886264
6.

Sequence determinants of protein aggregation in human VH domains.

Dudgeon K, Famm K, Christ D.

Protein Eng Des Sel. 2009 Mar;22(3):217-20. doi: 10.1093/protein/gzn059. Epub 2008 Oct 28.

PMID:
18957405
7.

Thermodynamically stable aggregation-resistant antibody domains through directed evolution.

Famm K, Hansen L, Christ D, Winter G.

J Mol Biol. 2008 Feb 29;376(4):926-31. doi: 10.1016/j.jmb.2007.10.075. Epub 2007 Nov 4.

PMID:
18199455
8.

Repertoires of aggregation-resistant human antibody domains.

Christ D, Famm K, Winter G.

Protein Eng Des Sel. 2007 Aug;20(8):413-6. Epub 2007 Aug 24.

PMID:
17720749
9.

Beta-edge interactions in a pentadecameric human antibody V kappa domain.

James LC, Jones PC, McCoy A, Tennent GA, Pepys MB, Famm K, Winter G.

J Mol Biol. 2007 Mar 30;367(3):603-8. Epub 2006 Nov 3.

PMID:
17292396
10.

Tapping diversity lost in transformations--in vitro amplification of ligation reactions.

Christ D, Famm K, Winter G.

Nucleic Acids Res. 2006;34(16):e108. Epub 2006 Aug 31.

11.

Aggregation-resistant domain antibodies selected on phage by heat denaturation.

Jespers L, Schon O, Famm K, Winter G.

Nat Biotechnol. 2004 Sep;22(9):1161-5. Epub 2004 Aug 8.

PMID:
15300256
12.

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