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Age-Related Dopaminergic Innervation Augments T Helper 2-Type Allergic Inflammation in the Postnatal Lung.

Wang W, Cohen JA, Wallrapp A, Trieu KG, Barrios J, Shao F, Krishnamoorthy N, Kuchroo VK, Jones MR, Fine A, Bai Y, Ai X.

Immunity. 2019 Nov 18. pii: S1074-7613(19)30446-7. doi: 10.1016/j.immuni.2019.10.002. [Epub ahead of print]


Leukocyte function assessed via serial microlitre sampling of peripheral blood from sepsis patients correlates with disease severity.

Jundi B, Ryu H, Lee DH, Abdulnour RE, Engstrom BD, Duvall MG, Higuera A, Pinilla-Vera M, Benson ME, Lee J, Krishnamoorthy N, Baron RM, Han J, Voldman J, Levy BD.

Nat Biomed Eng. 2019 Dec;3(12):961-973. doi: 10.1038/s41551-019-0473-5. Epub 2019 Nov 11.


Next Generation Sequencing and Animal Models Reveal SLC9A3R1 as a New Gene Involved in Human Age-Related Hearing Loss.

Girotto G, Morgan A, Krishnamoorthy N, Cocca M, Brumat M, Bassani S, La Bianca M, Di Stazio M, Gasparini P.

Front Genet. 2019 Feb 26;10:142. doi: 10.3389/fgene.2019.00142. eCollection 2019.


Non-type 2 inflammation in severe asthma is propelled by neutrophil cytoplasts and maintained by defective resolution.

Duvall MG, Krishnamoorthy N, Levy BD.

Allergol Int. 2019 Apr;68(2):143-149. doi: 10.1016/j.alit.2018.11.006. Epub 2018 Dec 17. Review.


Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interaction.

Da'as SI, Fakhro K, Thanassoulas A, Krishnamoorthy N, Saleh A, Calver BL, Safieh-Garabedian B, Toft E, Nounesis G, Lai FA, Nomikos M.

Biochem J. 2018 Dec 14;475(24):3933-3948. doi: 10.1042/BCJ20180685.


In silico and in vivo models for Qatari-specific classical homocystinuria as basis for development of novel therapies.

Ismail HM, Krishnamoorthy N, Al-Dewik N, Zayed H, Mohamed NA, Giacomo VD, Gupta S, Häberle J, Thöny B, Blom HJ, Kruger WD, Ben-Omran T, Nasrallah GK.

Hum Mutat. 2019 Feb;40(2):230-240. doi: 10.1002/humu.23682. Epub 2018 Nov 23.


Next-generation sequencing identified SPATC1L as a possible candidate gene for both early-onset and age-related hearing loss.

Morgan A, Vuckovic D, Krishnamoorthy N, Rubinato E, Ambrosetti U, Castorina P, Franzè A, Vozzi D, La Bianca M, Cappellani S, Di Stazio M, Gasparini P, Girotto G.

Eur J Hum Genet. 2019 Jan;27(1):70-79. doi: 10.1038/s41431-018-0229-9. Epub 2018 Sep 3.


Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma.

Krishnamoorthy N, Douda DN, Brüggemann TR, Ricklefs I, Duvall MG, Abdulnour RE, Martinod K, Tavares L, Wang X, Cernadas M, Israel E, Mauger DT, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Wenzel S, Dunican E, Fahy JV, Irimia D, Wagner DD, Levy BD; National Heart, Lung, and Blood Institute Severe Asthma Research Program-3 Investigators.

Sci Immunol. 2018 Aug 3;3(26). pii: eaao4747. doi: 10.1126/sciimmunol.aao4747.


Specialized Proresolving Mediators in Innate and Adaptive Immune Responses in Airway Diseases.

Krishnamoorthy N, Abdulnour RE, Walker KH, Engstrom BD, Levy BD.

Physiol Rev. 2018 Jul 1;98(3):1335-1370. doi: 10.1152/physrev.00026.2017. Review.


15-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 Induce NF-κB Regulators in Bacterial Pneumonia.

Sham HP, Walker KH, Abdulnour RE, Krishnamoorthy N, Douda DN, Norris PC, Barkas I, Benito-Figueroa S, Colby JK, Serhan CN, Levy BD.

J Immunol. 2018 Apr 15;200(8):2757-2766. doi: 10.4049/jimmunol.1602090. Epub 2018 Mar 9.


Towards developing a vaccine for rheumatic heart disease.

Gandhi GD, Krishnamoorthy N, Motal UMA, Yacoub M.

Glob Cardiol Sci Pract. 2017 Mar 31;2017(1):e201704. doi: 10.21542/gcsp.2017.4. Review.


Augmented Responses to Ozone in Obese Mice Require IL-17A and Gastrin-Releasing Peptide.

Mathews JA, Krishnamoorthy N, Kasahara DI, Hutchinson J, Cho Y, Brand JD, Williams AS, Wurmbrand AP, Ribeiro L, Cuttitta F, Sunday ME, Levy BD, Shore SA.

Am J Respir Cell Mol Biol. 2018 Mar;58(3):341-351. doi: 10.1165/rcmb.2017-0071OC.


Natural killer cell-mediated inflammation resolution is disabled in severe asthma.

Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Israel E, Levy BD; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators.

Sci Immunol. 2017 Mar 10;2(9). pii: eaam5446. doi: 10.1126/sciimmunol.aam5446.


Targeted sequencing identifies novel variants involved in autosomal recessive hereditary hearing loss in Qatari families.

Alkowari MK, Vozzi D, Bhagat S, Krishnamoorthy N, Morgan A, Hayder Y, Logendra B, Najjar N, Gandin I, Gasparini P, Badii R, Girotto G, Abdulhadi K.

Mutat Res. 2017 Aug;800-802:29-36. doi: 10.1016/j.mrfmmm.2017.05.001. Epub 2017 May 4.


A Strategy to Enhance Secretion of Extracellular Matrix Components by Stem Cells: Relevance to Tissue Engineering.

Krishnamoorthy N, Tseng YT, Gajendrarao P, Sarathchandra P, McCormack A, Carubelli I, Sohier J, Latif N, Chester AH, Yacoub MH.

Tissue Eng Part A. 2018 Jan;24(1-2):145-156. doi: 10.1089/ten.TEA.2017.0060. Epub 2017 Jul 19.


Bionomics of Anopheles fluviatilis and Anopheles culicifacies (Diptera: Culicidae) in Relation to Malaria Transmission in East-Central India.

Sahu SS, Gunasekaran K, Krishnamoorthy N, Vanamail P, Mathivanan A, Manonmani A, Jambulingam P.

J Med Entomol. 2017 Jul 1;54(4):821-830. doi: 10.1093/jme/tjx065.


Improving iodine nutritional status and increasing prevalence of autoimmune thyroiditis in children.

Palaniappan S, Shanmughavelu L, Prasad HK, Subramaniam S, Krishnamoorthy N, Lakkappa L.

Indian J Endocrinol Metab. 2017 Jan-Feb;21(1):85-89. doi: 10.4103/2230-8210.195996.


The Role of Cardiac Myosin Binding Protein C3 in Hypertrophic Cardiomyopathy-Progress and Novel Therapeutic Opportunities.

Mohamed IA, Krishnamoorthy NT, Nasrallah GK, Da'as SI.

J Cell Physiol. 2017 Jul;232(7):1650-1659. doi: 10.1002/jcp.25639. Epub 2017 Feb 16. Review.


Two patients with Canavan disease and structural modeling of a novel mutation.

Zaki OK, Krishnamoorthy N, El Abd HS, Harche SA, Mattar RA, Al Disi RS, Nofal MY, El Bekay R, Ahmed KA, George Priya Doss C, Zayed H.

Metab Brain Dis. 2017 Feb;32(1):171-177. doi: 10.1007/s11011-016-9896-9. Epub 2016 Aug 17.


IL-33 Drives Augmented Responses to Ozone in Obese Mice.

Mathews JA, Krishnamoorthy N, Kasahara DI, Cho Y, Wurmbrand AP, Ribeiro L, Smith D, Umetsu D, Levy BD, Shore SA.

Environ Health Perspect. 2017 Feb;125(2):246-253. doi: 10.1289/EHP272. Epub 2016 Jul 29.


Glioblastoma with signet ring cell morphology: A diagnostic challenge.

Krishnamoorthy N, Veldore V, Sridhar PS, Govindrajan MJ, Prabhudesai S, Hazarika D, Ajaikumar BS.

Asian J Neurosurg. 2016 Jul-Sep;11(3):319-20. doi: 10.4103/1793-5482.149998.


Impact of disease-causing mutations on inter-domain interactions in cMyBP-C: a steered molecular dynamics study.

Krishnamoorthy N, Gajendrarao P, Olivotto I, Yacoub M.

J Biomol Struct Dyn. 2017 Jul;35(9):1916-1922. doi: 10.1080/07391102.2016.1199329. Epub 2016 Jun 30.


Hashimoto's Thyroiditis in South Indian Centre.

Rajamanickam R, Shanmugavelu L, Subramanian S, Prasad HK, Krishnamoorthy N.

Indian J Pediatr. 2016 Nov;83(11):1227-1231. Epub 2016 Apr 20.


Mast cell-derived neurotrophin 4 mediates allergen-induced airway hyperinnervation in early life.

Patel KR, Aven L, Shao F, Krishnamoorthy N, Duvall MG, Levy BD, Ai X.

Mucosal Immunol. 2016 Nov;9(6):1466-1476. doi: 10.1038/mi.2016.11. Epub 2016 Feb 10.


Genomic profiling in a homogeneous molecular subtype of non-small cell lung cancer: An effort to explore new drug targets.

Veldore VH, Patil S, Satheesh CT, Shashidhara HP, Tejaswi R, Prabhudesai SA, Krishnamoorthy N, Hazarika D, Naik R, Rao RM, Ajai Kumar BS.

Indian J Cancer. 2015 Apr-Jun;52(2):243-8. doi: 10.4103/0019-509X.175843.


Structural modeling of p.V31F variant in the aspartoacylase gene.

Krishnamoorthy N, Zayed H.

Metab Brain Dis. 2016 Jun;31(3):723-6. doi: 10.1007/s11011-016-9796-z. Epub 2016 Jan 21.


Targeted Therapy Management in NSCLC Patients Using Cytology: Experience from a Tertiary Care Cancer Center.

Veldore VH, Patil S, Prabhudesai S, Satheesh CT, Shashidhara HP, Krishnamoorthy N, Hazarika D, Tejaswi R, Prabhudev A, Naik R, Rao RM, Kumar BS.

Mol Diagn Ther. 2016 Apr;20(2):119-23. doi: 10.1007/s40291-015-0180-1.


NaNog: A pluripotency homeobox (master) molecule.

Allouba MH, ElGuindy AM, Krishnamoorthy N, Yacoub MH, Aguib YE.

Glob Cardiol Sci Pract. 2015 Oct 15;2015(3):36. doi: 10.5339/gcsp.2015.36. eCollection 2015.


Cryopreserved Human Precision-Cut Lung Slices as a Bioassay for Live Tissue Banking. A Viability Study of Bronchodilation with Bitter-Taste Receptor Agonists.

Bai Y, Krishnamoorthy N, Patel KR, Rosas I, Sanderson MJ, Ai X.

Am J Respir Cell Mol Biol. 2016 May;54(5):656-63. doi: 10.1165/rcmb.2015-0290MA.


Genetic modifiers to the PLN L39X mutation in a patient with DCM and sustained ventricular tachycardia?

Sanoudou D, Kolokathis F, Arvanitis D, Al-Shafai K, Krishnamoorthy N, Buchan RJ, Walsh R, Tsiapras D, Barton PJ, Cook SA, Kremastinos D, Yacoub M.

Glob Cardiol Sci Pract. 2015 Jul 3;2015(2):29. doi: 10.5339/gcsp.2015.29. eCollection 2015. No abstract available.


Deltamethrin induced functional mortality of Anopheles stephensi, the urban malaria vector, in relation to resistance development.

Aarumugam P, Krishnamoorthy N, Gunasekaran K.

J Vector Borne Dis. 2015 Sep;52(3):261-4. No abstract available.


Superficial temporal artery pseudoaneurysm presenting as extradural hematoma: A case report and review of literature.

Madhusudan HV, Krishnamoorthy N, Suresh PK, Subramaniam V.

Asian J Neurosurg. 2015 Apr-Jun;10(2):63-5. doi: 10.4103/1793-5482.154870. Review.


An Investigation of the Molecular Mechanism of Double cMyBP-C Mutation in a Patient with End-Stage Hypertrophic Cardiomyopathy.

Gajendrarao P, Krishnamoorthy N, Selvaraj S, Girolami F, Cecchi F, Olivotto I, Yacoub M.

J Cardiovasc Transl Res. 2015 Jun;8(4):232-43. doi: 10.1007/s12265-015-9624-6. Epub 2015 May 14.


Cutting edge: maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation.

Krishnamoorthy N, Burkett PR, Dalli J, Abdulnour RE, Colas R, Ramon S, Phipps RP, Petasis NA, Kuchroo VK, Serhan CN, Levy BD.

J Immunol. 2015 Feb 1;194(3):863-7. doi: 10.4049/jimmunol.1402534. Epub 2014 Dec 24.


Maresin 1 biosynthesis during platelet-neutrophil interactions is organ-protective.

Abdulnour RE, Dalli J, Colby JK, Krishnamoorthy N, Timmons JY, Tan SH, Colas RA, Petasis NA, Serhan CN, Levy BD.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16526-31. doi: 10.1073/pnas.1407123111. Epub 2014 Nov 4.


Prevalence of KRAS mutations in metastatic colorectal cancer: A retrospective observational study from India.

Veldore VH, Rao MR, Prabhudesai SA, Tejaswi R, Kakara S, Pattanayak S, Krishnamoorthy N, Tejaswini BN, Hazarika D, Gangoli A, Rahman SM, Dixit J, Naik R, Diwakar RB, Satheesh CT, Shashidhara HP, Patil S, Gopinath KS, Kumar BS.

Indian J Cancer. 2014 Oct-Dec;51(4):531-7. doi: 10.4103/0019-509X.175371.


Management of Hodgkin's lymphoma with midbrain involvement: A case report and review of literature.

Maka VV, Chitrapur R, Kilara N, Prabhu VM, Krishnamoorthy N.

Hematology. 2015 Jun;20(5):272-5. doi: 10.1179/1607845414Y.0000000190. Epub 2014 Aug 18. Review.


Cutting Edge: MMP-9 inhibits IL-23p19 expression in dendritic cells by targeting membrane stem cell factor affecting lung IL-17 response.

Oriss TB, Krishnamoorthy N, Raundhal M, Morse C, Chakraborty K, Khare A, Huff R, Ray P, Ray A.

J Immunol. 2014 Jun 15;192(12):5471-5475. doi: 10.4049/jimmunol.1303183. Epub 2014 May 14.


Isolated nasopharyngeal metastasis from hepatocellular carcinoma.

Kattepur AK, Patil DB, Krishnamoorthy N, Srinivas KG, Swamy S, Amarendra S, Gopinath KS.

Int J Surg Case Rep. 2014;5(3):115-7. doi: 10.1016/j.ijscr.2013.12.009. Epub 2014 Jan 3.


Evaluation of natural radioactivity and its associated health hazard indices of a South Indian river.

Krishnamoorthy N, Mullainathan S, Mehra R, Chaparro MA, Chaparro MA.

Radiat Prot Dosimetry. 2014 Dec;162(3):364-74. doi: 10.1093/rpd/nct288. Epub 2013 Dec 6.


Dendritic cell c-kit signaling and adaptive immunity: implications for the upper airways.

Oriss TB, Krishnamoorthy N, Ray P, Ray A.

Curr Opin Allergy Clin Immunol. 2014 Feb;14(1):7-12. doi: 10.1097/ACI.0000000000000019. Review.


Epidermal growth factor receptor mutation in non-small-cell lung carcinomas: a retrospective analysis of 1036 lung cancer specimens from a network of tertiary cancer care centers in India.

Veldore VH, Rao RM, Kakara S, Pattanayak S, Tejaswi R, Sahoo R, Venkataswamy E, Prabhudesai SA, Krishnamoorthy N, Tejaswini BN, Hazarika D, Gangoli SA, Rahman SM, Naik R, Diwakar RB, Satheesh CT, Shashidhar SP, Patil SG, Ajai Kumar BS.

Indian J Cancer. 2013 Apr-Jun;50(2):87-93. doi: 10.4103/0019-509X.117013.


Cutting edge: inhaled antigen upregulates retinaldehyde dehydrogenase in lung CD103+ but not plasmacytoid dendritic cells to induce Foxp3 de novo in CD4+ T cells and promote airway tolerance.

Khare A, Krishnamoorthy N, Oriss TB, Fei M, Ray P, Ray A.

J Immunol. 2013 Jul 1;191(1):25-9. doi: 10.4049/jimmunol.1300193. Epub 2013 Jun 3.


Molecular modeling of disease causing mutations in domain C1 of cMyBP-C.

Gajendrarao P, Krishnamoorthy N, Kassem HSh, Moharem-Elgamal S, Cecchi F, Olivotto I, Yacoub MH.

PLoS One. 2013;8(3):e59206. doi: 10.1371/journal.pone.0059206. Epub 2013 Mar 19.


DNA Barcodes indicate members of the Anopheles fluviatilis (Diptera: Culicidae) species complex to be conspecific in India.

Pradeep Kumar N, Krishnamoorthy N, Sahu SS, Rajavel AR, Sabesan S, Jambulingam P.

Mol Ecol Resour. 2013 May;13(3):354-61. doi: 10.1111/1755-0998.12076. Epub 2013 Feb 11.


Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma.

Krishnamoorthy N, Khare A, Oriss TB, Raundhal M, Morse C, Yarlagadda M, Wenzel SE, Moore ML, Peebles RS Jr, Ray A, Ray P.

Nat Med. 2012 Oct;18(10):1525-30. doi: 10.1038/nm.2896. Epub 2012 Sep 9.


Glycogen storage disease type V (Mc Ardle's disease): a report on three cases.

Krishnamoorthy N, Santosh V, Yasha TC, Mahadevan A, Shankar SK, Jethwani D, Taly AB, Bhanu K, Gayathri N.

Neurol India. 2011 Nov-Dec;59(6):884-6. doi: 10.4103/0028-3886.91370.


Lymphangiosarcoma arising after 33 years within a background of chronic filariasis: a case report with review of literature.

Krishnamoorthy N, Viswanathan S, Rekhi B, Jambhekar NA.

J Cutan Pathol. 2012 Jan;39(1):52-5. doi: 10.1111/j.1600-0560.2011.01785.x. Review.


A clinico-morphological study of 95 cases of sarcomas with metastases to the lungs.

Krishnamoorthy N, Desai SS, Rekhi B, Jambhekar NA.

Indian J Cancer. 2011 Jul-Sep;48(3):335-8. doi: 10.4103/0019-509X.84942.


A computational modeling approach for enhancing self-assembly and biofunctionalisation of collagen biomimetic peptides.

Krishnamoorthy N, Yacoub MH, Yaliraki SN.

Biomaterials. 2011 Oct;32(30):7275-85. doi: 10.1016/j.biomaterials.2011.06.074. Epub 2011 Jul 26.


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