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Akt determines cell fate through inhibition of the PERK-eIF2α phosphorylation pathway.

Mounir Z, Krishnamoorthy JL, Wang S, Papadopoulou B, Campbell S, Muller WJ, Hatzoglou M, Koromilas AE.

Sci Signal. 2011 Sep 27;4(192):ra62. doi: 10.1126/scisignal.2001630.


Tumor suppression by PTEN requires the activation of the PKR-eIF2alpha phosphorylation pathway.

Mounir Z, Krishnamoorthy JL, Robertson GP, Scheuner D, Kaufman RJ, Georgescu MM, Koromilas AE.

Sci Signal. 2009 Dec 22;2(102):ra85. doi: 10.1126/scisignal.2000389.


A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway.

Kazemi S, Mounir Z, Baltzis D, Raven JF, Wang S, Krishnamoorthy JL, Pluquet O, Pelletier J, Koromilas AE.

Mol Biol Cell. 2007 Sep;18(9):3635-44. Epub 2007 Jun 27.

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