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Items: 1 to 50 of 260

1.

Drug permeation against efflux by two transporters.

Saha P, Sikdar S, Krishnamoorthy G, Zgurskaya HI, Rybenkov VV.

ACS Infect Dis. 2020 Feb 10. doi: 10.1021/acsinfecdis.9b00510. [Epub ahead of print]

PMID:
32039579
2.

FX11 limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid through host-directed activity.

Krishnamoorthy G, Kaiser P, Abed UA, Weiner J 3rd, Moura-Alves P, Brinkmann V, Kaufmann SHE.

Dis Model Mech. 2020 Feb 7. pii: dmm.041954. doi: 10.1242/dmm.041954. [Epub ahead of print]

3.

Aryl Hydrocarbon Receptor Modulation by Tuberculosis Drugs Impairs Host Defense and Treatment Outcomes.

Puyskens A, Stinn A, van der Vaart M, Kreuchwig A, Protze J, Pei G, Klemm M, Guhlich-Bornhof U, Hurwitz R, Krishnamoorthy G, Schaaf M, Krause G, Meijer AH, Kaufmann SHE, Moura-Alves P.

Cell Host Microbe. 2020 Feb 12;27(2):238-248.e7. doi: 10.1016/j.chom.2019.12.005. Epub 2019 Dec 31.

PMID:
31901518
4.

Isothermal titration calorimetry and surface plasmon resonance analysis using the dynamic approach.

Krishnamoorthy GK, Alluvada P, Hameed Mohammed Sherieff S, Kwa T, Krishnamoorthy J.

Biochem Biophys Rep. 2019 Dec 17;21:100712. doi: 10.1016/j.bbrep.2019.100712. eCollection 2020 Mar.

5.

Impact of quercetin on tight junctional proteins and BDNF signaling molecules in hippocampus of PCBs-exposed rats.

Selvakumar K, Bavithra S, Krishnamoorthy G, Arunakaran J.

Interdiscip Toxicol. 2018 Dec;11(4):294-305. doi: 10.2478/intox-2018-0029. Epub 2019 Oct 18.

6.

Use of 6-Methylisoxanthopterin, a Fluorescent Guanine Analog, to Probe Fob1-Mediated Dynamics at the Stalling Fork Barrier DNA Sequences.

Mariam J, Krishnamoorthy G, Anand R.

Chem Asian J. 2019 Dec 13;14(24):4760-4766. doi: 10.1002/asia.201901061. Epub 2019 Oct 24.

PMID:
31647188
7.

α-Synuclein Spontaneously Adopts Stable and Reversible α-Helical Structure in Water-Less Environment.

Mukhopadhyay A, Mehra S, Kumar R, Maji SK, Krishnamoorthy G, Sharma KP.

Chemphyschem. 2019 Nov 5;20(21):2783-2790. doi: 10.1002/cphc.201900868. Epub 2019 Oct 14.

PMID:
31515915
8.

To study the effect of Cocos nucifera oil when incorporated into tissue conditioner on its tensile strength and antifungal activity: An in vitro study.

Krishnamoorthy G, Narayana AI, Peralam PY, Balkrishanan D.

J Indian Prosthodont Soc. 2019 Jul-Sep;19(3):225-232. doi: 10.4103/jips.jips_387_18.

9.

Efflux Pumps of Burkholderia thailandensis Control the Permeability Barrier of the Outer Membrane.

Krishnamoorthy G, Weeks JW, Zhang Z, Chandler CE, Xue H, Schweizer HP, Ernst RK, Zgurskaya HI.

Antimicrob Agents Chemother. 2019 Sep 23;63(10). pii: e00956-19. doi: 10.1128/AAC.00956-19. Print 2019 Oct.

PMID:
31383661
10.

Effect of biosurfactant derived from Vibrio natriegens MK3 against Vibrio harveyi biofilm and virulence.

Kannan S, Krishnamoorthy G, Kulanthaiyesu A, Marudhamuthu M.

J Basic Microbiol. 2019 Sep;59(9):936-949. doi: 10.1002/jobm.201800706. Epub 2019 Jul 26.

PMID:
31347191
11.

Observation of Continuous Contraction and a Metastable Misfolded State during the Collapse and Folding of a Small Protein.

Bhatia S, Krishnamoorthy G, Dhar D, Udgaonkar JB.

J Mol Biol. 2019 Sep 6;431(19):3814-3826. doi: 10.1016/j.jmb.2019.07.024. Epub 2019 Jul 19.

PMID:
31330152
12.

Tweaking the proton transfer triggered proton transfer of 3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazole.

Das M, Sahu S, Krishnamoorthy G.

Phys Chem Chem Phys. 2019 Jul 17;21(28):15669-15677. doi: 10.1039/c9cp02281c.

PMID:
31271171
13.

Chlorin e6 decorated doxorubicin encapsulated chitosan nanoparticles for photo-controlled cancer drug delivery.

Bhatta A, Krishnamoorthy G, Marimuthu N, Dihingia A, Manna P, Biswal HT, Das M, Krishnamoorthy G.

Int J Biol Macromol. 2019 Sep 1;136:951-961. doi: 10.1016/j.ijbiomac.2019.06.127. Epub 2019 Jun 19.

PMID:
31226376
14.

Mycofactocin Is Associated with Ethanol Metabolism in Mycobacteria.

Krishnamoorthy G, Kaiser P, Lozza L, Hahnke K, Mollenkopf HJ, Kaufmann SHE.

mBio. 2019 May 21;10(3). pii: e00190-19. doi: 10.1128/mBio.00190-19.

15.

Design of biostable scaffold based on collagen crosslinked by dialdehyde chitosan with presence of gallic acid.

Bam P, Bhatta A, Krishnamoorthy G.

Int J Biol Macromol. 2019 Jun 1;130:836-844. doi: 10.1016/j.ijbiomac.2019.03.017. Epub 2019 Mar 4.

PMID:
30844463
16.

Fusobacterium Septicemia with Liver and Lung Abscesses Due to Diverticulitis.

Sharma A, Goyal S, Arsene C, Krishnamoorthy G, Ehrinpreis M.

ACG Case Rep J. 2018 Dec 19;5:e99. doi: 10.14309/crj.2018.99. eCollection 2018.

17.

Humanized Mouse Model Mimicking Pathology of Human Tuberculosis for in vivo Evaluation of Drug Regimens.

Arrey F, Löwe D, Kuhlmann S, Kaiser P, Moura-Alves P, Krishnamoorthy G, Lozza L, Maertzdorf J, Skrahina T, Skrahina A, Gengenbacher M, Nouailles G, Kaufmann SHE.

Front Immunol. 2019 Jan 31;10:89. doi: 10.3389/fimmu.2019.00089. eCollection 2019.

18.

Complete resolution of erythrodermic psoriasis with first-line apremilast monotherapy.

Krishnamoorthy G, Kotecha A, Pimentel J.

BMJ Case Rep. 2019 Jan 31;12(1). pii: e226959. doi: 10.1136/bcr-2018-226959.

PMID:
30709830
19.

BReDi mouse: A novel transgenic mouse strain to track and deplete B cells.

Mues M, Krishnamoorthy G.

Eur J Immunol. 2019 Mar;49(3):500-503. doi: 10.1002/eji.201847930. Epub 2019 Jan 11.

PMID:
30578685
20.

Conformational flexibility of histone variant CENP-ACse4 is regulated by histone H4: A mechanism to stabilize soluble Cse4.

Malik N, Dantu SC, Shukla S, Kombrabail M, Ghosh SK, Krishnamoorthy G, Kumar A.

J Biol Chem. 2018 Dec 28;293(52):20273-20284. doi: 10.1074/jbc.RA118.004141. Epub 2018 Oct 31.

21.

Comment on "Michael Addition Based Chemodosimeter for Serum Creatinine Detection Using ( E)-3-(Pyren-2-yl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one Chalcone".

Ila, Chipem FAS, Krishnamoorthy G.

ACS Sens. 2018 Nov 26;3(11):2463-2466. doi: 10.1021/acssensors.8b00434. Epub 2018 Oct 31.

PMID:
30345734
22.

Proton transfer triggered proton transfer: a self-assisted twin excited state intramolecular proton transfer.

Sahu S, Das M, Bharti AK, Krishnamoorthy G.

Phys Chem Chem Phys. 2018 Oct 31;20(42):27131-27139. doi: 10.1039/c8cp03835j.

PMID:
30334032
23.

EIF1AX and RAS Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC.

Krishnamoorthy GP, Davidson NR, Leach SD, Zhao Z, Lowe SW, Lee G, Landa I, Nagarajah J, Saqcena M, Singh K, Wendel HG, Dogan S, Tamarapu PP, Blenis J, Ghossein RA, Knauf JA, Rätsch G, Fagin JA.

Cancer Discov. 2019 Feb;9(2):264-281. doi: 10.1158/2159-8290.CD-18-0606. Epub 2018 Oct 10.

24.

Mastication as a tool to prevent cognitive dysfunctions.

Krishnamoorthy G, Narayana AI, Balkrishanan D.

Jpn Dent Sci Rev. 2018 Nov;54(4):169-173. doi: 10.1016/j.jdsr.2018.06.001. Epub 2018 Aug 31. Review.

25.

Emerging Role of Diet and Microbiota Interactions in Neuroinflammation.

Janakiraman M, Krishnamoorthy G.

Front Immunol. 2018 Sep 11;9:2067. doi: 10.3389/fimmu.2018.02067. eCollection 2018. Review.

26.

Bioactive compound from Aspergillus terreusDMTMGK004 synergistically contributes towards potential anti-pathogenicity.

Krishnamoorthy G, Kannan S, Marudhamuthu M.

Lett Appl Microbiol. 2018 Dec;67(6):579-588. doi: 10.1111/lam.13071. Epub 2018 Oct 18.

PMID:
30203855
27.

Log D analysis using dynamic approach.

Krishnamoorthy G, Alluvada P, Alemayehu E, Mohammed Sherieff SH, Addi WA, Kwa T, Krishnamoorthy J.

Biochem Biophys Rep. 2018 Sep 3;16:1-11. doi: 10.1016/j.bbrep.2018.07.006. eCollection 2018 Dec.

28.

Acute Hepatitis due to Garcinia Cambogia Extract, an Herbal Weight Loss Supplement.

Sharma A, Akagi E, Njie A, Goyal S, Arsene C, Krishnamoorthy G, Ehrinpreis M.

Case Rep Gastrointest Med. 2018 Jul 26;2018:9606171. doi: 10.1155/2018/9606171. eCollection 2018.

29.

Phagosomal Copper-Promoted Oxidative Attack on Intracellular Mycobacterium tuberculosis.

Libardo MDJ, de la Fuente-Nuñez C, Anand K, Krishnamoorthy G, Kaiser P, Pringle SC, Dietz C, Pierce S, Smith MB, Barczak A, Kaufmann SHE, Singh A, Angeles-Boza AM.

ACS Infect Dis. 2018 Nov 9;4(11):1623-1634. doi: 10.1021/acsinfecdis.8b00171. Epub 2018 Sep 6.

PMID:
30141623
30.

Site-Specific Fluorescence Dynamics To Probe Polar Arrest by Fob1 in Replication Fork Barrier Sequences.

Biswas A, Mariam J, Kombrabail M, Narayan S, Krishnamoorthy G, Anand R.

ACS Omega. 2017 Oct 31;2(10):7389-7399. doi: 10.1021/acsomega.7b01117. Epub 2017 Oct 30.

31.

Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein.

Spadaro M, Winklmeier S, Beltrán E, Macrini C, Höftberger R, Schuh E, Thaler FS, Gerdes LA, Laurent S, Gerhards R, Brändle S, Dornmair K, Breithaupt C, Krumbholz M, Moser M, Krishnamoorthy G, Kamp F, Jenne D, Hohlfeld R, Kümpfel T, Lassmann H, Kawakami N, Meinl E.

Ann Neurol. 2018 Aug;84(2):315-328. doi: 10.1002/ana.25291. Epub 2018 Sep 9.

PMID:
30014603
32.
33.

Dietary non-fermentable fiber prevents autoimmune neurological disease by changing gut metabolic and immune status.

Berer K, Martínez I, Walker A, Kunkel B, Schmitt-Kopplin P, Walter J, Krishnamoorthy G.

Sci Rep. 2018 Jul 11;8(1):10431. doi: 10.1038/s41598-018-28839-3.

34.

Tipifarnib Inhibits HRAS-Driven Dedifferentiated Thyroid Cancers.

Untch BR, Dos Anjos V, Garcia-Rendueles MER, Knauf JA, Krishnamoorthy GP, Saqcena M, Bhanot UK, Socci ND, Ho AL, Ghossein R, Fagin JA.

Cancer Res. 2018 Aug 15;78(16):4642-4657. doi: 10.1158/0008-5472.CAN-17-1925. Epub 2018 May 14.

35.

Molecular Properties That Define the Activities of Antibiotics in Escherichia coli and Pseudomonas aeruginosa.

Cooper SJ, Krishnamoorthy G, Wolloscheck D, Walker JK, Rybenkov VV, Parks JM, Zgurskaya HI.

ACS Infect Dis. 2018 Aug 10;4(8):1223-1234. doi: 10.1021/acsinfecdis.8b00036. Epub 2018 May 25.

36.

Trans-envelope multidrug efflux pumps of Gram-negative bacteria and their synergism with the outer membrane barrier.

Zgurskaya HI, Rybenkov VV, Krishnamoorthy G, Leus IV.

Res Microbiol. 2018 Sep - Oct;169(7-8):351-356. doi: 10.1016/j.resmic.2018.02.002. Epub 2018 Feb 16. Review.

37.

Kinetic Control of Quorum Sensing in Pseudomonas aeruginosa by Multidrug Efflux Pumps.

Wolloscheck D, Krishnamoorthy G, Nguyen J, Zgurskaya HI.

ACS Infect Dis. 2018 Feb 9;4(2):185-195. doi: 10.1021/acsinfecdis.7b00160. Epub 2017 Nov 10.

38.

Synergy between Active Efflux and Outer Membrane Diffusion Defines Rules of Antibiotic Permeation into Gram-Negative Bacteria.

Krishnamoorthy G, Leus IV, Weeks JW, Wolloscheck D, Rybenkov VV, Zgurskaya HI.

mBio. 2017 Oct 31;8(5). pii: e01172-17. doi: 10.1128/mBio.01172-17.

39.

Site-specific time-resolved FRET reveals local variations in the unfolding mechanism in an apparently two-state protein unfolding transition.

Bhatia S, Krishnamoorthy G, Udgaonkar JB.

Phys Chem Chem Phys. 2018 Jan 31;20(5):3216-3232. doi: 10.1039/c7cp06214a.

PMID:
29085950
40.

Bifurcation kinetics of drug uptake by Gram-negative bacteria.

Westfall DA, Krishnamoorthy G, Wolloscheck D, Sarkar R, Zgurskaya HI, Rybenkov VV.

PLoS One. 2017 Sep 19;12(9):e0184671. doi: 10.1371/journal.pone.0184671. eCollection 2017.

41.

Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice.

Berer K, Gerdes LA, Cekanaviciute E, Jia X, Xiao L, Xia Z, Liu C, Klotz L, Stauffer U, Baranzini SE, Kümpfel T, Hohlfeld R, Krishnamoorthy G, Wekerle H.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10719-10724. doi: 10.1073/pnas.1711233114. Epub 2017 Sep 11.

42.

Perturbation of cationic equilibrium by cucurbit-7-uril.

Behera SK, Krishnamoorthy G.

Phys Chem Chem Phys. 2017 Jul 26;19(29):19234-19242. doi: 10.1039/c7cp03583g.

PMID:
28702607
43.

p53 amyloid formation leading to its loss of function: implications in cancer pathogenesis.

Ghosh S, Salot S, Sengupta S, Navalkar A, Ghosh D, Jacob R, Das S, Kumar R, Jha NN, Sahay S, Mehra S, Mohite GM, Ghosh SK, Kombrabail M, Krishnamoorthy G, Chaudhari P, Maji SK.

Cell Death Differ. 2017 Oct;24(10):1784-1798. doi: 10.1038/cdd.2017.105. Epub 2017 Jun 23.

44.

Optics within life sciences 2016.

Maiti S, Krishnamoorthy G.

Methods Appl Fluoresc. 2017 Apr 4;5(2):020201. doi: 10.1088/2050-6120/aa668d. No abstract available.

PMID:
28374680
45.

Site-specific structural dynamics of α-Synuclein revealed by time-resolved fluorescence spectroscopy: a review.

Sahay S, Krishnamoorthy G, Maji SK.

Methods Appl Fluoresc. 2016 Oct 11;4(4):042002. doi: 10.1088/2050-6120/4/4/042002. Review.

PMID:
28192290
46.

Advanced functional luminogens in the solid-state: general discussion.

Pucci A, Leung N, Hor A, Wu S, Gu Y, Li B, Liu B, Hu R, Qin A, Chen X, Li Z, Zhang D, Krishnamoorthy G, Pasini D, Tsuchiya Y, Wang K, He X, Peng H, Zhao Z, He G, Tang BZ, Rivard E, Ito F, Tian H, Zhu MQ, Sun JZ, Chujo Y, Kuang G, Ma Y, Tian W, Xu B, Tsutsumi O, Duan P.

Faraday Discuss. 2017 Feb 1;196:317-334. doi: 10.1039/C7FD90001E. Epub 2017 Feb 7. No abstract available.

PMID:
28168263
47.

New and efficient fluorescent and phosphorescent luminogens: general discussion.

Leung N, Pucci A, Hu R, Campbell EE, Krishnamoorthy G, Tang BZ, Wu S, Zhang F, Mei J, Bai W, Li B, He X, Tang Y, Liu B, Zhang R, Wang Z, Qin A, Li Z, Zhang D, Pasini D, Tian W, Tsuchiya Y, Jadhav T, Wang Y, Zhao Z, He G, Li K, Rivard E, Zhu MQ, Xu B, Sun JZ, Chujo Y, Hong JL, Kong L, Lu P, Chang CC, Wang K, Singh RA.

Faraday Discuss. 2017 Feb 7. doi: 10.1039/C7FD90003A. [Epub ahead of print] No abstract available.

PMID:
28168261
48.

Biomedical applications of luminogens: general discussion.

Pucci A, Hor A, Gao M, Wu S, Yu Y, Li B, He X, Liu B, Hu R, Lou X, Li Z, Krishnamoorthy G, Zhang D, Pasini D, Tang Y, Tsuchiya Y, Wang Y, Yuan WZ, Tang BZ, Ding D, Tian H, Zhu MQ, Sun JZ, Tian W, Kuang G, Wu L, Chen J, Zhang R, Jadhav T.

Faraday Discuss. 2017 Feb 1;196:403-414. doi: 10.1039/C7FD90002C. Epub 2017 Feb 7. No abstract available.

PMID:
28168247
49.

Optoelectronic devices of highly efficient luminogens in the solid state: general discussion.

Wu S, He X, Liu B, Hu R, Li Z, Krishnamoorthy G, Qin A, Tang Y, Pasini D, Tsuchiya Y, Jadhav T, Zhao Z, Peng H, Tian H, Sun JZ, Zhu MQ, Ma Y, Tang BZ.

Faraday Discuss. 2017 Feb 1;196:455-460. doi: 10.1039/C7FD90004J. Epub 2017 Feb 3. No abstract available.

PMID:
28155965
50.

Depth-Dependent Membrane Ordering by Hemagglutinin Fusion Peptide Promotes Fusion.

Chakraborty H, Lentz BR, Kombrabail M, Krishnamoorthy G, Chattopadhyay A.

J Phys Chem B. 2017 Feb 23;121(7):1640-1648. doi: 10.1021/acs.jpcb.7b00684. Epub 2017 Feb 9.

PMID:
28125233

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